Downward lab

Oncogene Biology Laboratory

 Publications

Mass cytometry images of carcinogen induced lung tumours in mice.

Publications

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Displaying 1 - 19 of 19
Last updated : 24 April 2024 03:40

Spatial architecture of myeloid and T cells orchestrates immune evasion and clinical outcome in lung cancer

Authors (35)
Cancer Discovery
Published
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Antibodies against endogenous retroviruses promote lung cancer immunotherapy

Authors (51)
Nature
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Genomic-transcriptomic evolution in lung cancer and metastasis

Authors (47)
Nature
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Lung adenocarcinoma promotion by air pollutants

Authors (72)
Nature
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Lysosomal damage drives mitochondrial proteome remodelling and reprograms macrophage immunometabolism

Authors (17)
Nature Communications
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An immunogenic model of KRAS-mutant lung cancer enables evaluation of targeted therapy and immunotherapy combinations

Authors (26)
Cancer Research
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Therapeutic KRASG12C inhibition drives effective interferon-mediated antitumor immunity in immunogenic lung cancers

Authors (14)
Science advances
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Characterisation of tumour microenvironment remodelling following oncogene inhibition in preclinical studies with imaging mass cytometry

Authors (18)
Nature Communications
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Combined targeting of G protein-coupled receptor and EGF receptor signaling overcomes resistance to PI3K pathway inhibitors in PTEN-null triple negative breast cancer

Authors (7)
EMBO Molecular Medicine
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Development of combination therapies to maximize the impact of KRAS-G12C inhibitors in lung cancer

Authors (12)
Science Translational Medicine
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RAC1P29S induces a mesenchymal phenotypic switch via serum response factor to promote melanoma development and therapy resistance

Authors (17)
Cancer Cell
Published
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