Downward lab

Oncogene Biology Laboratory

 Publications

Mass cytometry images of carcinogen induced lung tumours in mice.

Publications

Year published

Research topics

Publication type

Journal

Displaying 1 - 20 of 21
Last updated : 24 April 2024 02:57

Antibodies against endogenous retroviruses promote lung cancer immunotherapy

Authors (51)
Nature
Published
Crick labs/ facilities
Full details

Genomic-transcriptomic evolution in lung cancer and metastasis

Authors (47)
Nature
Published
Crick labs/ facilities
Full details

Lung adenocarcinoma promotion by air pollutants

Authors (72)
Nature
Published
Crick labs/ facilities
Full details

Lysosomal damage drives mitochondrial proteome remodelling and reprograms macrophage immunometabolism

Authors (17)
Nature Communications
Published
Crick labs/ facilities
Full details

An immunogenic model of KRAS-mutant lung cancer enables evaluation of targeted therapy and immunotherapy combinations

Authors (26)
Cancer Research
Published
Crick labs/ facilities
Full details

Therapeutic KRASG12C inhibition drives effective interferon-mediated antitumor immunity in immunogenic lung cancers

Authors (14)
Science advances
Published
Crick labs/ facilities
Full details

Characterisation of tumour microenvironment remodelling following oncogene inhibition in preclinical studies with imaging mass cytometry

Authors (18)
Nature Communications
Published
Crick labs/ facilities
Full details

Combined targeting of G protein-coupled receptor and EGF receptor signaling overcomes resistance to PI3K pathway inhibitors in PTEN-null triple negative breast cancer

Authors (7)
EMBO Molecular Medicine
Published
Crick labs/ facilities
Full details

IGF1-mediated human embryonic stem cell self-renewal recapitulates the embryonic niche

Authors (17)
Nature Communications
Published
Crick labs/ facilities
Full details

Development of combination therapies to maximize the impact of KRAS-G12C inhibitors in lung cancer

Authors (12)
Science Translational Medicine
Published
Crick labs/ facilities
Full details

RAC1P29S induces a mesenchymal phenotypic switch via serum response factor to promote melanoma development and therapy resistance

Authors (17)
Cancer Cell
Published
Crick labs/ facilities
Full details