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Breadcrumb Julian Downward Downward lab Oncogene Biology Laboratory : Publications Lab contentLab contentIn this section Overview Areas of interest Publications Members Vacancies Lab news Mass cytometry images of carcinogen induced lung tumours in mice. Toggle to view hero caption PublicationsYear published (-)2014 (7) Facet Year publishedPublication typeJournal article (7)Primary research (5)Commentary (1)Review (1) Facet Publication typeJournalBritish Journal of Cancer (1)Cancer Cell (1)Cancer Discovery (1)Cancer Research (1)Carcinogenesis (1)Journal of Clinical Investigation (1)Nature Cell Biology (1) Facet Journal Publications Displaying 1 - 7 of 7Last updated : 16 April 2024 03:52 ASPP2 controls epithelial plasticity and inhibits metastasis through β-catenin-dependent regulation of ZEB1 Authors (24) Yihua Wang Fangfang Bu Christophe Royer Sébastien Serres James R Larkin Manuel Sarmiento Soto[...] Robert D Goldin Jian Zhao Xin Tong Yajun Guo Xin Lu Nature Cell Biology Published 1 November 2014 Crick labsJulian DownwardFull details Chromosomal instability selects gene copy-number variants encoding core regulators of proliferation in ER+ breast cancer Authors (9) David Endesfelder Rebecca A Burrell Nnennaya Kanu Nicholas McGranahanMichael HowellPeter ParkerJulian DownwardCharles Swanton Maik Kschischo Cancer Research Published 1 September 2014 Crick labs/ facilitiesCharles SwantonPeter ParkerJulian DownwardHigh Throughput ScreeningFull details Guidelines for the use of cell lines in biomedical research Authors (12) RJ Geraghty A Capes-Davis JM DavisJulian Downward RI Freshney I Knezevic[...] JRW Masters J Meredith GN Stacey P Thraves M Vias British Journal of Cancer Published 12 August 2014 Crick labsRobin Lovell-BadgeJulian DownwardFull details RAS interaction with PI3K p110α is required for tumor-induced angiogenesis Authors (7) Miguel Manuel Murillo Santiago ZelenayEmma Nye Esther Castellano François Lassailly Gordon StampJulian Downward Journal of Clinical Investigation Published 1 August 2014 Crick labs/ facilitiesJulian DownwardLight MicroscopyExperimental HistopathologyFull details Reduced NF1 expression confers resistance to EGFR inhibition in lung cancer Authors (20) Elza C de Bruin Catherine Cowell Patricia H Warne Ming Jiang Rebecca E Saunders Mary Ann Melnick[...] Harold Varmus René Bernards Egbert F Smit Katerina PolitiJulian Downward Cancer Discovery Published 1 May 2014 Crick labs/ facilitiesJulian DownwardHigh Throughput ScreeningFull details Regulation of polarized morphogenesis by protein kinase C iota in oncogenic epithelial spheroids Authors (13) Mark Linch Marta Sanz-Garcia Carine Rosse Philippe Riou Nick Peel Chris D Madsen[...] Asim Khwaja Christian Dillon Jon Roffey Angus JM CameronPeter Parker Carcinogenesis Published 1 February 2014 Crick labsErik SahaiPeter ParkerJulian DownwardFull details RAS's cloak of invincibility slips at last? Authors (1)Julian Downward Cancer Cell Published 13 January 2014 Crick labsJulian DownwardFull details Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
ASPP2 controls epithelial plasticity and inhibits metastasis through β-catenin-dependent regulation of ZEB1 Authors (24) Yihua Wang Fangfang Bu Christophe Royer Sébastien Serres James R Larkin Manuel Sarmiento Soto[...] Robert D Goldin Jian Zhao Xin Tong Yajun Guo Xin Lu Nature Cell Biology Published 1 November 2014 Crick labsJulian DownwardFull details
Chromosomal instability selects gene copy-number variants encoding core regulators of proliferation in ER+ breast cancer Authors (9) David Endesfelder Rebecca A Burrell Nnennaya Kanu Nicholas McGranahanMichael HowellPeter ParkerJulian DownwardCharles Swanton Maik Kschischo Cancer Research Published 1 September 2014 Crick labs/ facilitiesCharles SwantonPeter ParkerJulian DownwardHigh Throughput ScreeningFull details
Guidelines for the use of cell lines in biomedical research Authors (12) RJ Geraghty A Capes-Davis JM DavisJulian Downward RI Freshney I Knezevic[...] JRW Masters J Meredith GN Stacey P Thraves M Vias British Journal of Cancer Published 12 August 2014 Crick labsRobin Lovell-BadgeJulian DownwardFull details
RAS interaction with PI3K p110α is required for tumor-induced angiogenesis Authors (7) Miguel Manuel Murillo Santiago ZelenayEmma Nye Esther Castellano François Lassailly Gordon StampJulian Downward Journal of Clinical Investigation Published 1 August 2014 Crick labs/ facilitiesJulian DownwardLight MicroscopyExperimental HistopathologyFull details
Reduced NF1 expression confers resistance to EGFR inhibition in lung cancer Authors (20) Elza C de Bruin Catherine Cowell Patricia H Warne Ming Jiang Rebecca E Saunders Mary Ann Melnick[...] Harold Varmus René Bernards Egbert F Smit Katerina PolitiJulian Downward Cancer Discovery Published 1 May 2014 Crick labs/ facilitiesJulian DownwardHigh Throughput ScreeningFull details
Regulation of polarized morphogenesis by protein kinase C iota in oncogenic epithelial spheroids Authors (13) Mark Linch Marta Sanz-Garcia Carine Rosse Philippe Riou Nick Peel Chris D Madsen[...] Asim Khwaja Christian Dillon Jon Roffey Angus JM CameronPeter Parker Carcinogenesis Published 1 February 2014 Crick labsErik SahaiPeter ParkerJulian DownwardFull details
RAS's cloak of invincibility slips at last? Authors (1)Julian Downward Cancer Cell Published 13 January 2014 Crick labsJulian DownwardFull details
