Publications

Embracing cancer complexity: Hallmarks of systemic disease

Authors (33)

Charles Swanton
Elsa Bernard
Chris Abbosh
Fabrice André
Johan Auwerx
Allan Balmain
[...]
Eileen White
Frank Winkler
John N Wood
Karen Vousden
Douglas Hanahan

Cell

Published 28 March 2024

Crick labs

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Recovering from the stress of the COVID-19 pandemic

Authors (6)

Samantha C Lewis
Alexis A Jourdain
Brenda A Schulman
Karen Vousden
Jacqueline M Fabius
Haipeng Liu

Molecular Cell

Published 4 January 2024

Crick labs

Karen Vousden

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Phenotypic profiling of solute carriers characterizes serine transport in cancer

Authors (12)

Vassilis Papalazarou
Alice C Newman
Alejandro Huerta-Uribe
Nathalie Legrave
Mattia Falcone
Tong Zhang
[...]
Dimitris Athineos
Emma Shanks
Karen Blyth
Karen Vousden
Oliver DK Maddocks

Nature Metabolism

Published 1 December 2023

Crick labs/ facilities

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The role of APOBEC3B in lung tumor evolution and targeted cancer therapy resistance

Authors (85)

Deborah Caswell
Philippe Gui
Manasi K Mayekar
Emily K Law
Oriol Pich
Chris Bailey
[...]
Nnennaya Kanu
Reuben S Harris
Julian Downward
Trever G Bivona
Charles Swanton

Nature Genetics

Published 1 January 2024

Crick labs/ facilities

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A century of the Warburg effect

Authors (11)

Craig B Thompson
Karen Vousden
Randall S Johnson
Willem H Koppenol
Helmut Sies
Zhimin Lu
Lydia WS Finley
Christian Frezza
Jiyeon Kim
Zeping Hu
Caroline R Bartman

Nature Metabolism

Published 1 November 2023

Crick labs

Karen Vousden

Full details

Loss of attachment promotes proline accumulation and excretion in cancer cells

Authors (8)

Steven Pilley
Marc Hennequart
Anke Vandekeere
Julianna Blagih
Nathalie Legrave
Sarah-Maria Fendt
Karen Vousden
Christiaan F Labuschagne

Science advances

Published 6 September 2023

Crick labs/ facilities

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ALDH1L2 regulation of formate, formyl-methionine, and ROS controls cancer cell migration and metastasis

Authors (20)

Cell Reports

Published 26 May 2023

Crick labs/ facilities

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Canagliflozin impairs T cell effector function via metabolic suppression in autoimmunity

Authors (23)

Benjamin J Jenkins
Julianna Blagih
Fernando M Ponce-Garcia
Mary Canavan
Nancy Gudgeon
Simon Eastham
[...]
Ursula Fearon
Gareth W Jones
Linda V Sinclair
Emma E Vincent
Nicholas Jones

Cell Metabolism

Published 11 July 2023

Crick labs/ facilities

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Apoptotic cell death in disease-Current understanding of the NCCD 2023

Authors (228)

Ilio Vitale
Federico Pietrocola
Emma Guilbaud
Stuart A Aaronson
John M Abrams
Dieter Adam
[...]
Boris Zhivotovsky
Wenzhao Zhou
Mauro Piacentini
Guido Kroemer
Lorenzo Galluzzi

Cell Death and Differentiation

Published 1 May 2023

Crick labs

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The dietary sweetener sucralose is a negative modulator of T cell-mediated responses

Authors (16)

Fabio Zani
Julianna Blagih
Tim Gruber
Michael Buck
Nicholas Jones
Marc Hennequart
[...]
Eric Cheung
Ian S Gilmore
Alex Gould
Cristina Garcia-Caceres
Karen Vousden

Nature

Published 23 March 2023

Crick labs/ facilities

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Reflections on Terri

Authors (1)

Karen Vousden

Genes and Development

Published 1 January 2023

Crick labs

Karen Vousden

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B-cell receptor signaling induced metabolic alterations in chronic lymphocytic leukemia can be partially bypassed by TP53 abnormalities

Authors (7)

Katarina Kluckova
Andrew J Clear
Annalisa D'Avola
Laura Z Rassenti
Thomas J Kipps
John G Gribben
John Riches

HemaSphere

Published 1 June 2022

Crick labs

Karen Vousden

Full details

PHGDH is required for germinal center formation and is a therapeutic target in MYC-driven lymphoma

Authors (17)

Annalisa D'Avola
Nathalie Legrave
Mylene Tajan
Probir Chakravarty
Ryan L Shearer
Hamish W King
[...]
James Macrae
John G Gribben
Dinis Calado
Karen Vousden
John Riches

Journal of Clinical Investigation

Published 2 May 2022

Crick labs/ facilities

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A noninvasive iRFP713 p53 reporter reveals dynamic p53 activity in response to irradiation and liver regeneration in vivo

Authors (12)

Tim Humpton
Andreas K Hock
Christos Kiourtis
Marco De Donatis
Frédéric Fercoq
Colin Nixon
[...]
Douglas Strathdee
Leo M Carlin
Thomas G Bird
Karen Blyth
Karen Vousden

Science Signaling

Published 8 February 2022

Crick labs/ facilities

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The role of ROS in tumour development and progression

Authors (2)

Nature Reviews Cancer

Published 1 May 2022

Crick labs

Karen Vousden

Full details

A celebration of the life of George Vande Woude

Authors (2)

Sue VandeWoude
Karen Vousden

Proceedings of the National Academy of Sciences of USA

Published 7 December 2021

Crick labs

Karen Vousden

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The impact of physiological metabolite levels on serine uptake, synthesis and utilization in cancer cells

Authors (8)

Nature Communications

Published 26 October 2021

Crick labs/ facilities

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p53-mediated redox control promotes liver regeneration and maintains liver function in response to CCl4

Authors (10)

Tim Humpton
Holly Hall
Christos Kiourtis
Colin Nixon
William Clark
Ann Hedley
Robin Shaw
Thomas G Bird
Karen Blyth
Karen Vousden

Cell Death and Differentiation

Published 1 March 2022

Crick labs

Karen Vousden

Full details

More Metabolism!

Authors (11)

James A Olzmann
Sarah-Maria Fendt
Yatrik Shah
Karen Vousden
Navdeep Chandel
Tiffany Horng
Nika Danial
Benjamin Tu
Heather Christofk
Matthew G Vander Heiden
Kathryn Wellen

Molecular Cell

Published 16 September 2021

Crick labs

Karen Vousden

Full details

Tissue nutrient environments and their effect on regulatory T cell biology

Authors (3)

Frontiers in Immunology

Published 1 April 2021

Crick labs

Karen Vousden

Full details

Research case studies

Postdoctoral clinical fellows

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p53 and Metabolism Laboratory
: Publications

Lab content

Publications

Year published

Research topics

Publication type

Journal

Embracing cancer complexity: Hallmarks of systemic disease

Recovering from the stress of the COVID-19 pandemic

Phenotypic profiling of solute carriers characterizes serine transport in cancer

The role of APOBEC3B in lung tumor evolution and targeted cancer therapy resistance

A century of the Warburg effect

Loss of attachment promotes proline accumulation and excretion in cancer cells

ALDH1L2 regulation of formate, formyl-methionine, and ROS controls cancer cell migration and metastasis

Canagliflozin impairs T cell effector function via metabolic suppression in autoimmunity

Apoptotic cell death in disease-Current understanding of the NCCD 2023

The dietary sweetener sucralose is a negative modulator of T cell-mediated responses

Reflections on Terri

B-cell receptor signaling induced metabolic alterations in chronic lymphocytic leukemia can be partially bypassed by TP53 abnormalities

PHGDH is required for germinal center formation and is a therapeutic target in MYC-driven lymphoma

A noninvasive iRFP713 p53 reporter reveals dynamic p53 activity in response to irradiation and liver regeneration in vivo

The role of ROS in tumour development and progression

A celebration of the life of George Vande Woude

The impact of physiological metabolite levels on serine uptake, synthesis and utilization in cancer cells

p53-mediated redox control promotes liver regeneration and maintains liver function in response to CCl4

More Metabolism!

Tissue nutrient environments and their effect on regulatory T cell biology

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Research case studies

Postdoctoral clinical fellows

Hello Brain!

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