Publications

Attenuation of reverse transcriptase facilitates SAMHD1 restriction of HIV-1 in cycling cells

Authors (9)

Chloe Tsai
Sarah Caswell
Liz Morris
Melanie C Mann
Simon Pennell
Geoff Kelly
Harriet CT Groom
Ian Taylor
Kate Bishop

Retrovirology

Published 1 May 2023

Crick labs/ facilities

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SARS-CoV-2 ORF6 disrupts innate immune signalling by inhibiting cellular mRNA export

Authors (7)

PLOS Pathogens

Published 25 August 2022

Crick labs/ facilities

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HIV-1 requires capsid remodelling at the nuclear pore for nuclear entry and integration

Authors (6)

Anabel Guedan
Callum D Donaldson
Eve Caroe
Ophélie Cosnefroy
Ian Taylor
Kate Bishop

PLOS Pathogens

Published 20 September 2021

Crick labs/ facilities

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The role of capsid in HIV-1 nuclear entry

Authors (4)

Viruses

Published 1 August 2021

Crick labs

Kate Bishop

Full details

Analysis of SAMHD1 restriction by flow cytometry in human myeloid U937 cells

Authors (4)

Paula Ordonez Suarez
Kate Bishop
Jonathan Stoye
Harriet Cordelia Theed Groom

Journal of Visualized Experiments

Published 13 June 2021

Crick labs

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HIV-1 Gag recruits oligomeric Vpr via two binding sites in p6, but both mature p6 and Vpr are rapidly lost upon target cell entry

Authors (2)

Journal of Virology

Published 1 September 2021

Crick labs

Kate Bishop

Full details

Positive selection in dNTPase SAMHD1 throughout mammalian evolution

Authors (12)

Christopher Monit
Liz Morris
Christopher Ruis
Bart Szafran
Grant Thiltgen
Chloe Tsai
[...]
Kate Bishop
Jonathan Stoye
Ian Taylor
Ariberto Fassati
Richard A Goldstein

Proceedings of the National Academy of Sciences of the United States of America

Published 10 September 2019

Crick labs

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Gammaretroviruses tether to mitotic chromatin by directly binding nucleosomal histone proteins

Authors (2)

Microbial Cell

Published 1 August 2018

Crick labs

Kate Bishop

Full details

Murine leukemia virus p12 tethers the capsid-containing pre-integration complex to chromatin by binding directly to host nucleosomes in mitosis

Authors (5)

PLOS Pathogens

Published 15 June 2018

Crick labs/ facilities

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SAMHD1 enhances nucleoside-analogue efficacy against HIV-1 in myeloid cells

Authors (9)

Scientific Reports

Published 21 February 2017

Crick labs/ facilities

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HIV-1 capsid uncoating initiates after the first strand transfer of reverse transcription

Authors (3)

Ophélie Cosnefroy
Philip J Murray
Kate Bishop

Retrovirology

Published 22 August 2016

Crick labs

Kate Bishop

Full details

Phospho-dependent regulation of SAMHD1 oligomerisation couples catalysis and restriction

Authors (15)

Laurence H Arnold
Harriet CT Groom
Simone Kunzelmann
David Schwefel
Sarah Caswell
Paula Ordonez Suarez
[...]
Steven A Howell
Jonathan Stoye
Michelle Webb
Ian Taylor
Kate Bishop

PLOS Pathogens

Published 2 October 2015

Crick labs/ facilities

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Molecular determinants for recognition of divergent SAMHD1 proteins by the lentiviral accessory protein Vpx

Authors (7)

David Schwefel
Virginie C Boucherit
Evangelos Christodoulou
Philip Walker
Jonathan Stoye
Kate Bishop
Ian Taylor

Cell Host & Microbe

Published 8 April 2015

Crick labs/ facilities

Full details

Cell culture

Authors (2)

Cd Donaldson
Kate Bishop

British Journal of Hospital Medicine

Published 1 January 2015

Crick labs

Kate Bishop

Full details

Structural basis of lentiviral subversion of a cellular protein degradation pathway

Authors (8)

David Schwefel
Harriet CT Groom
Virginie C Boucherit
Evangelos Christodoulou
Philip Walker
Jonathan Stoye
Kate Bishop
Ian Taylor

Nature

Published 15 December 2014

Crick labs/ facilities

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The N-terminus of murine leukaemia virus p12 protein is required for mature core stability

Authors (9)

Darren J Wight
Virginie C Boucherit
Madushi Wanaguru
Efrat Elis
Elizabeth MA Hirst
Wilson Li
Marcelo Ehrlich
Eran Bacharach
Kate Bishop

PLOS Pathogens

Published 1 October 2014

Crick labs/ facilities

Full details

Chronic fatigue syndrome, the immune system and viral infection

Authors (5)

AS Bansal
AS Bradley
Kate Bishop
S Kiani-Alikhan
B Ford

Brain, Behavior, and Immunity

Published 2 July 2012

Crick labs

Kate Bishop

Full details

No evidence for infection of UK prostate cancer patients with XMRV, BK virus, Trichomonas vaginalis or human papilloma viruses

Authors (4)

Harriet CT Groom
Anne Y Warren
David E Neal
Kate Bishop

PLOS ONE

Published 1 January 2012

Crick labs

Kate Bishop

Full details

The gammaretroviral p12 protein has multiple domains that function during the early stages of replication

Authors (6)

Darren J Wight
Virginie C Boucherit
Mirella Nader
David J Allen
Ian Taylor
Kate Bishop

Retrovirology

Published 1 January 2012

Crick labs

Full details

The tale of xenotropic murine leukemia virus-related virus

Authors (2)

Harriet CT Groom
Kate Bishop

Journal of General Virology

Published 1 January 2012

Crick labs

Kate Bishop

Full details

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Retroviral Replication Laboratory
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Journal

Attenuation of reverse transcriptase facilitates SAMHD1 restriction of HIV-1 in cycling cells

SARS-CoV-2 ORF6 disrupts innate immune signalling by inhibiting cellular mRNA export

HIV-1 requires capsid remodelling at the nuclear pore for nuclear entry and integration

The role of capsid in HIV-1 nuclear entry

Analysis of SAMHD1 restriction by flow cytometry in human myeloid U937 cells

HIV-1 Gag recruits oligomeric Vpr via two binding sites in p6, but both mature p6 and Vpr are rapidly lost upon target cell entry

Positive selection in dNTPase SAMHD1 throughout mammalian evolution

Gammaretroviruses tether to mitotic chromatin by directly binding nucleosomal histone proteins

Murine leukemia virus p12 tethers the capsid-containing pre-integration complex to chromatin by binding directly to host nucleosomes in mitosis

SAMHD1 enhances nucleoside-analogue efficacy against HIV-1 in myeloid cells

HIV-1 capsid uncoating initiates after the first strand transfer of reverse transcription

Phospho-dependent regulation of SAMHD1 oligomerisation couples catalysis and restriction

Molecular determinants for recognition of divergent SAMHD1 proteins by the lentiviral accessory protein Vpx

Cell culture

Structural basis of lentiviral subversion of a cellular protein degradation pathway

The N-terminus of murine leukaemia virus p12 protein is required for mature core stability

Chronic fatigue syndrome, the immune system and viral infection

No evidence for infection of UK prostate cancer patients with XMRV, BK virus, Trichomonas vaginalis or human papilloma viruses

The gammaretroviral p12 protein has multiple domains that function during the early stages of replication

The tale of xenotropic murine leukemia virus-related virus

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