Research case studies Explore a selection of reports that spotlight particular areas of research at the Crick over the past five years.
Postdoctoral clinical fellows Opportunities for postdoctoral clinicians to consolidate their research experience.
Breadcrumb Kate Bishop Bishop lab Retroviral Replication Laboratory : Publications Lab contentLab contentIn this section Overview Vacancies Areas of interest Publications Members Electron microscope image of mouse leukaemia virus-like particles containing a faulty p12 protein. Toggle to view hero caption PublicationsYear published2022 (1)2021 (1)2018 (1)2015 (1)2014 (1) Facet Year publishedResearch topicsBiochemistry & Proteomics (4)Cell Biology (4)Infectious Disease (4)Model Organisms (4)Structural Biology & Biophysics (4)Chemical Biology & High Throughput (3)Cell Cycle & Chromosomes (2)Computational & Systems Biology (2)Genetics & Genomics (2)Genome Integrity & Repair (2)Metabolism (1)Signalling & Oncogenes (1)Tumour Biology (1) Facet Research topicsPublication typeJournal article (5)Primary research (5) Facet Publication typeJournal (-)PLOS Pathogens (5) Facet Journal Publications Displaying 1 - 5 of 5Last updated : 24 April 2024 02:21 SARS-CoV-2 ORF6 disrupts innate immune signalling by inhibiting cellular mRNA export Authors (7)Ross HallAnabel GuedanMelvyn YapGeorge Young Ruth HarveyJonathan StoyeKate Bishop PLOS Pathogens Published 25 August 2022 Crick labs/ facilitiesJonathan StoyeKate BishopWorldwide Influenza CentreBioinformatics and BiostatisticsAdvanced SequencingFull details HIV-1 requires capsid remodelling at the nuclear pore for nuclear entry and integration Authors (6)Anabel Guedan Callum D DonaldsonEve Caroe Ophélie CosnefroyIan TaylorKate Bishop PLOS Pathogens Published 20 September 2021 Crick labs/ facilitiesIan TaylorKate BishopLight MicroscopyFull details Murine leukemia virus p12 tethers the capsid-containing pre-integration complex to chromatin by binding directly to host nucleosomes in mitosis Authors (5)Madushi WanaguruDavid BarryDonald BentonNicola O'ReillyKate Bishop PLOS Pathogens Published 15 June 2018 Crick labs/ facilitiesSteve GamblinKate BishopLight MicroscopyStructural BiologyFull details Phospho-dependent regulation of SAMHD1 oligomerisation couples catalysis and restriction Authors (15) Laurence H Arnold Harriet CT GroomSimone Kunzelmann David SchwefelSarah CaswellPaula Ordonez Suarez[...] Steven A HowellJonathan Stoye Michelle WebbIan TaylorKate Bishop PLOS Pathogens Published 2 October 2015 Crick labs/ facilitiesIan TaylorJonathan StoyeSteve SmerdonKate BishopStructural BiologyProteomicsFull details The N-terminus of murine leukaemia virus p12 protein is required for mature core stability Authors (9) Darren J Wight Virginie C Boucherit Madushi Wanaguru Efrat Elis Elizabeth MA Hirst Wilson Li Marcelo Ehrlich Eran BacharachKate Bishop PLOS Pathogens Published 1 October 2014 Crick labs/ facilitiesKate BishopElectron MicroscopyFull details Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
SARS-CoV-2 ORF6 disrupts innate immune signalling by inhibiting cellular mRNA export Authors (7)Ross HallAnabel GuedanMelvyn YapGeorge Young Ruth HarveyJonathan StoyeKate Bishop PLOS Pathogens Published 25 August 2022 Crick labs/ facilitiesJonathan StoyeKate BishopWorldwide Influenza CentreBioinformatics and BiostatisticsAdvanced SequencingFull details
HIV-1 requires capsid remodelling at the nuclear pore for nuclear entry and integration Authors (6)Anabel Guedan Callum D DonaldsonEve Caroe Ophélie CosnefroyIan TaylorKate Bishop PLOS Pathogens Published 20 September 2021 Crick labs/ facilitiesIan TaylorKate BishopLight MicroscopyFull details
Murine leukemia virus p12 tethers the capsid-containing pre-integration complex to chromatin by binding directly to host nucleosomes in mitosis Authors (5)Madushi WanaguruDavid BarryDonald BentonNicola O'ReillyKate Bishop PLOS Pathogens Published 15 June 2018 Crick labs/ facilitiesSteve GamblinKate BishopLight MicroscopyStructural BiologyFull details
Phospho-dependent regulation of SAMHD1 oligomerisation couples catalysis and restriction Authors (15) Laurence H Arnold Harriet CT GroomSimone Kunzelmann David SchwefelSarah CaswellPaula Ordonez Suarez[...] Steven A HowellJonathan Stoye Michelle WebbIan TaylorKate Bishop PLOS Pathogens Published 2 October 2015 Crick labs/ facilitiesIan TaylorJonathan StoyeSteve SmerdonKate BishopStructural BiologyProteomicsFull details
The N-terminus of murine leukaemia virus p12 protein is required for mature core stability Authors (9) Darren J Wight Virginie C Boucherit Madushi Wanaguru Efrat Elis Elizabeth MA Hirst Wilson Li Marcelo Ehrlich Eran BacharachKate Bishop PLOS Pathogens Published 1 October 2014 Crick labs/ facilitiesKate BishopElectron MicroscopyFull details