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Breadcrumb Katie Bentley Bentley lab Cellular Adaptive Behaviour Laboratory : Publications Lab contentLab contentIn this section Overview Areas of interest Members Publications Software Vacancies PublicationsYear published2022 (2)2021 (2)2020 (1)2019 (1)2016 (1)2014 (1) Facet Year publishedResearch topicsCell Biology (7)Chemical Biology & High Throughput (7)Developmental Biology (7)Imaging (7) Facet Research topicsCrick/Pre-CrickCrick publications (8)Pre-Crick publications (16) Facet Crick/Pre-CrickPublication typeJournal article (8)Primary research (8) Facet Publication typeJournaleLife (3)Cell Reports (1)iScience (1)Nature Cell Biology (1)Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences (1)PLoS Computational Biology (1) Facet Journal Publicatons Displaying 1 - 20 of 25Last updated : 09 December 2023 03:39 Engineered patterns of Notch ligands Jag1 and Dll4 elicit differential spatial control of endothelial sprouting Authors (9) Laura A Tiemeijer Tommaso Ristori Oscar MJA Stassen Jaakko J Ahlberg Jonne JJ de Bijl Christopher S ChenKatie Bentley Carlijn VC Bouten Cecilia M Sahlgren iScience Published 20 May 2022 Crick labsKatie BentleyFull details Notch controls the cell cycle to define leader versus follower identities during collective cell migration Authors (16)Zain AlhashemDylan Feldner-BusztinChristopher RevellMacarena Alvarez-Garcillan PortilloKaren Camargo-SosaJoanna Richardson[...]Natascia TisoRobert N KelshVictoria E PrinceKatie BentleyClaudia Linker eLife Published 19 April 2022 Crick labsKatie BentleyFull details OpenABM-Covid19-An agent-based model for non-pharmaceutical interventions against COVID-19 including contact tracing Authors (26) Robert Hinch William JM Probert Anel Nurtay Michelle Kendall Chris Wymant Matthew Hall[...] Tommaso Ristori Anthony Finkelstein David G Bonsall Lucie Abeler-Dörner Christophe Fraser PLoS Computational Biology Published 12 July 2021 Crick labsKatie BentleyFull details Active perception during angiogenesis: filopodia speed up Notch selection of tip cells in silico and in vivo Authors (10)Bahti Zakirov Georgios Charalambous Raphael ThuretIrene Aspalter Kelvin Van-Vuuren Thomas Mead Kyle Harrington Erzsébet Ravasz Regan Shane Paul HerbertKatie Bentley Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences Published 29 March 2021 Crick labsKatie BentleyFull details Blocking endothelial apoptosis revascularises the retina in a model of ischemic retinopathy Authors (13) Zoe L Grant Lachlan Whitehead Vickie HY Wong Zheng He Richard Y Yan Abigail R Miles[...] Claudia PrahstKatie Bentley Bang V Bui Robert CA Symons Leigh Coultas Journal of Clinical Investigation Published 3 August 2020 Crick labsKatie BentleyFull details Mouse retinal cell behaviour in space and time using light sheet fluorescence microscopy Authors (17) Claudia Prahst Parham Ashrafzadeh Thomas Mead Ana Figueiredo Karen Chang Douglas Richardson[...] Dong Feng Chen Lena Claesson-Welsh Kin-Sang Cho Claudio A FrancoKatie Bentley eLife Published 19 February 2020 Crick labs/ facilitiesKatie BentleyLight MicroscopyElectron MicroscopyFull details PKM2 regulates endothelial cell junction dynamics and angiogenesis via ATP production Authors (9) Jesús Gómez-Escudero Cristina Clemente Diego García-Weber Rebeca Acín-Pérez Jaime Millán José A EnríquezKatie Bentley Peter Carmeliet Alicia G Arroyo Scientific Reports Published 21 October 2019 Crick labsKatie BentleyFull details Positive feedback defines the timing, magnitude, and robustness of angiogenesis Authors (6) Donna J Page Raphael Thuret Lakshmi Venkatraman Tokiharu TakahashiKatie Bentley Shane P Herbert Cell Reports Published 11 June 2019 Crick labsKatie BentleyFull details NOTCH1 signaling induces pathological vascular permeability in diabetic retinopathy Authors (22) Khalil Miloudi Malika Oubaha Catherine Ménard Agnieszka Dejda Vera Guber Gael Cagnone[...] Jean-Sebastien Joyal Frédérick A Mallette Jean-Philippe Gratton Bruno Larrivée Przemyslaw Sapieha Proceedings of the National Academy of Sciences of the United States of America Published 5 March 2019 Crick labsKatie BentleyFull details Defective endothelial cell migration in the absence of Cdc42 leads to capillary-venous malformations Authors (10) Bàrbara Laviña Marco Castro Colin Niaudet Bert Cruys Alberto Álvarez-Aznar Peter CarmelietKatie Bentley Cord Brakebusch Christer Betsholtz Konstantin Gaengel Development Published 2 July 2018 Crick labsKatie BentleyFull details The temporal basis of angiogenesis Authors (2)Katie Bentley Shilpa Chakravartula Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences Published 19 May 2017 Crick labsKatie BentleyFull details Asymmetric division coordinates collective cell migration in angiogenesis Authors (7) Guilherme Costa Kyle I Harrington Holly E Lovegrove Donna J Page Shilpa ChakravartulaKatie Bentley Shane P Herbert Nature Cell Biology Published 1 December 2016 Crick labsKatie BentleyFull details Time to decide? Dynamical analysis predicts partial tip/stalk patterning states arise during angiogenesis Authors (3) Lakshmi Venkatraman Erzsébet Ravasz ReganKatie Bentley PLOS ONE Published 15 November 2016 Crick labsKatie BentleyFull details Glycolytic regulation of cell rearrangement in angiogenesis Authors (16) Bert Cruys Brian W Wong Anna Kuchnio Dries Verdegem Anna Rita Cantelmo Lena-Christin Conradi[...] Elisabetta Dejana Holger Gerhardt Mieke DewerchinKatie Bentley Peter Carmeliet Nature Communications Published 20 July 2016 Crick labsKatie BentleyFull details The endothelial adaptor molecule TSAd is required for VEGF-induced angiogenic sprouting through junctional c-Src activation Authors (12) Emma J Gordon Daisuke Fukuhara Simone Weström Narendra Padhan Elisabet O Sjöström Laurens van Meeteren[...] Fabrizio Orsenigo Elisabetta DejanaKatie Bentley Anne Spurkland Lena Claesson-Welsh Science Signaling Published 19 July 2016 Crick labsKatie BentleyFull details Synchronization of endothelial Dll4-Notch dynamics switches blood vessels from branching to expansion Authors (9) Benedetta Ubezio Raquel Agudo Blanco Ilse Geudens Fabio Stanchi Thomas MathivetMartin Jones Anan RagabKatie Bentley Holger Gerhardt eLife Published 13 April 2016 Crick labs/ facilitiesKatie BentleyElectron MicroscopyLight MicroscopyGenetic Modification ServiceBiological Research FacilityFull details VEGFR2 pY949 signalling regulates adherens junction integrity and metastatic spread Authors (19) Xiujuan Li Narendra Padhan Elisabet O Sjöström Francis P Roche Chiara Testini Naoki Honkura[...] Kurt Ballmer-Hofer Christer Betsholtz Kristian Pietras Leif Jansson Lena Claesson-Welsh Nature Communications Published 23 March 2016 Crick labsKatie BentleyFull details Temporal modulation of collective cell behavior controls vascular network topology Authors (8) Esther Kur Jiha Kim Aleksandra Tata Cesar H Comin Kyle I Harrington Luciano da F CostaKatie Bentley Chenghua Gu eLife Published 24 February 2016 Crick labsKatie BentleyFull details Formin-mediated actin polymerization at endothelial junctions is required for vessel lumen formation and stabilization Authors (11) Li-Kun Phng Véronique GebalaKatie Bentley Andrew Philippides Andrin Wacker Thomas Mathivet Loïc Sauteur Fabio Stanchi Heinz-Georg Belting Markus Affolter Holger Gerhardt Developmental Cell Published 12 January 2015 Crick labsKatie BentleyFull details Can active perception generate bistability? Heterogeneous collective dynamics and vascular patterning Authors (3)Katie Bentley Kyle Harrington Erzsébet Regan ALIFE 2014: The Fourteenth International Conference on the Synthesis and Simulation of Living Systems Published 1 July 2014 Crick labsKatie BentleyFull details Pagination Current page 1 Page 2 Next page Next Last page Last Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Engineered patterns of Notch ligands Jag1 and Dll4 elicit differential spatial control of endothelial sprouting Authors (9) Laura A Tiemeijer Tommaso Ristori Oscar MJA Stassen Jaakko J Ahlberg Jonne JJ de Bijl Christopher S ChenKatie Bentley Carlijn VC Bouten Cecilia M Sahlgren iScience Published 20 May 2022 Crick labsKatie BentleyFull details
Notch controls the cell cycle to define leader versus follower identities during collective cell migration Authors (16)Zain AlhashemDylan Feldner-BusztinChristopher RevellMacarena Alvarez-Garcillan PortilloKaren Camargo-SosaJoanna Richardson[...]Natascia TisoRobert N KelshVictoria E PrinceKatie BentleyClaudia Linker eLife Published 19 April 2022 Crick labsKatie BentleyFull details
OpenABM-Covid19-An agent-based model for non-pharmaceutical interventions against COVID-19 including contact tracing Authors (26) Robert Hinch William JM Probert Anel Nurtay Michelle Kendall Chris Wymant Matthew Hall[...] Tommaso Ristori Anthony Finkelstein David G Bonsall Lucie Abeler-Dörner Christophe Fraser PLoS Computational Biology Published 12 July 2021 Crick labsKatie BentleyFull details
Active perception during angiogenesis: filopodia speed up Notch selection of tip cells in silico and in vivo Authors (10)Bahti Zakirov Georgios Charalambous Raphael ThuretIrene Aspalter Kelvin Van-Vuuren Thomas Mead Kyle Harrington Erzsébet Ravasz Regan Shane Paul HerbertKatie Bentley Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences Published 29 March 2021 Crick labsKatie BentleyFull details
Blocking endothelial apoptosis revascularises the retina in a model of ischemic retinopathy Authors (13) Zoe L Grant Lachlan Whitehead Vickie HY Wong Zheng He Richard Y Yan Abigail R Miles[...] Claudia PrahstKatie Bentley Bang V Bui Robert CA Symons Leigh Coultas Journal of Clinical Investigation Published 3 August 2020 Crick labsKatie BentleyFull details
Mouse retinal cell behaviour in space and time using light sheet fluorescence microscopy Authors (17) Claudia Prahst Parham Ashrafzadeh Thomas Mead Ana Figueiredo Karen Chang Douglas Richardson[...] Dong Feng Chen Lena Claesson-Welsh Kin-Sang Cho Claudio A FrancoKatie Bentley eLife Published 19 February 2020 Crick labs/ facilitiesKatie BentleyLight MicroscopyElectron MicroscopyFull details
PKM2 regulates endothelial cell junction dynamics and angiogenesis via ATP production Authors (9) Jesús Gómez-Escudero Cristina Clemente Diego García-Weber Rebeca Acín-Pérez Jaime Millán José A EnríquezKatie Bentley Peter Carmeliet Alicia G Arroyo Scientific Reports Published 21 October 2019 Crick labsKatie BentleyFull details
Positive feedback defines the timing, magnitude, and robustness of angiogenesis Authors (6) Donna J Page Raphael Thuret Lakshmi Venkatraman Tokiharu TakahashiKatie Bentley Shane P Herbert Cell Reports Published 11 June 2019 Crick labsKatie BentleyFull details
NOTCH1 signaling induces pathological vascular permeability in diabetic retinopathy Authors (22) Khalil Miloudi Malika Oubaha Catherine Ménard Agnieszka Dejda Vera Guber Gael Cagnone[...] Jean-Sebastien Joyal Frédérick A Mallette Jean-Philippe Gratton Bruno Larrivée Przemyslaw Sapieha Proceedings of the National Academy of Sciences of the United States of America Published 5 March 2019 Crick labsKatie BentleyFull details
Defective endothelial cell migration in the absence of Cdc42 leads to capillary-venous malformations Authors (10) Bàrbara Laviña Marco Castro Colin Niaudet Bert Cruys Alberto Álvarez-Aznar Peter CarmelietKatie Bentley Cord Brakebusch Christer Betsholtz Konstantin Gaengel Development Published 2 July 2018 Crick labsKatie BentleyFull details
The temporal basis of angiogenesis Authors (2)Katie Bentley Shilpa Chakravartula Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences Published 19 May 2017 Crick labsKatie BentleyFull details
Asymmetric division coordinates collective cell migration in angiogenesis Authors (7) Guilherme Costa Kyle I Harrington Holly E Lovegrove Donna J Page Shilpa ChakravartulaKatie Bentley Shane P Herbert Nature Cell Biology Published 1 December 2016 Crick labsKatie BentleyFull details
Time to decide? Dynamical analysis predicts partial tip/stalk patterning states arise during angiogenesis Authors (3) Lakshmi Venkatraman Erzsébet Ravasz ReganKatie Bentley PLOS ONE Published 15 November 2016 Crick labsKatie BentleyFull details
Glycolytic regulation of cell rearrangement in angiogenesis Authors (16) Bert Cruys Brian W Wong Anna Kuchnio Dries Verdegem Anna Rita Cantelmo Lena-Christin Conradi[...] Elisabetta Dejana Holger Gerhardt Mieke DewerchinKatie Bentley Peter Carmeliet Nature Communications Published 20 July 2016 Crick labsKatie BentleyFull details
The endothelial adaptor molecule TSAd is required for VEGF-induced angiogenic sprouting through junctional c-Src activation Authors (12) Emma J Gordon Daisuke Fukuhara Simone Weström Narendra Padhan Elisabet O Sjöström Laurens van Meeteren[...] Fabrizio Orsenigo Elisabetta DejanaKatie Bentley Anne Spurkland Lena Claesson-Welsh Science Signaling Published 19 July 2016 Crick labsKatie BentleyFull details
Synchronization of endothelial Dll4-Notch dynamics switches blood vessels from branching to expansion Authors (9) Benedetta Ubezio Raquel Agudo Blanco Ilse Geudens Fabio Stanchi Thomas MathivetMartin Jones Anan RagabKatie Bentley Holger Gerhardt eLife Published 13 April 2016 Crick labs/ facilitiesKatie BentleyElectron MicroscopyLight MicroscopyGenetic Modification ServiceBiological Research FacilityFull details
VEGFR2 pY949 signalling regulates adherens junction integrity and metastatic spread Authors (19) Xiujuan Li Narendra Padhan Elisabet O Sjöström Francis P Roche Chiara Testini Naoki Honkura[...] Kurt Ballmer-Hofer Christer Betsholtz Kristian Pietras Leif Jansson Lena Claesson-Welsh Nature Communications Published 23 March 2016 Crick labsKatie BentleyFull details
Temporal modulation of collective cell behavior controls vascular network topology Authors (8) Esther Kur Jiha Kim Aleksandra Tata Cesar H Comin Kyle I Harrington Luciano da F CostaKatie Bentley Chenghua Gu eLife Published 24 February 2016 Crick labsKatie BentleyFull details
Formin-mediated actin polymerization at endothelial junctions is required for vessel lumen formation and stabilization Authors (11) Li-Kun Phng Véronique GebalaKatie Bentley Andrew Philippides Andrin Wacker Thomas Mathivet Loïc Sauteur Fabio Stanchi Heinz-Georg Belting Markus Affolter Holger Gerhardt Developmental Cell Published 12 January 2015 Crick labsKatie BentleyFull details
Can active perception generate bistability? Heterogeneous collective dynamics and vascular patterning Authors (3)Katie Bentley Kyle Harrington Erzsébet Regan ALIFE 2014: The Fourteenth International Conference on the Synthesis and Simulation of Living Systems Published 1 July 2014 Crick labsKatie BentleyFull details