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Breadcrumb Katrin Rittinger Rittinger lab Molecular Structure of Cell Signalling Laboratory : Publications Lab contentLab contentIn this section Overview Areas of interest Publications Members Vacancies Two different representations of tetra-ubiquitin - a molecular 'tag' used to mark proteins inside cells. Toggle to view hero caption PublicationsYear published2023 (6)2022 (3)2020 (4)2019 (3)2018 (6)2017 (5)2016 (6)2015 (2) Facet Year publishedResearch topicsBiochemistry & Proteomics (35)Immunology (35)Infectious Disease (35)Signalling & Oncogenes (35)Structural Biology & Biophysics (35)Computational & Systems Biology (4)Metabolism (2)Model Organisms (2)Tumour Biology (2)Cell Biology (1)Developmental Biology (1)Genetics & Genomics (1)Human Biology & Physiology (1)Imaging (1) (-)Chemical Biology & High Throughput (35) Facet Research topicsPublication typeJournal article (35)Primary research (24)Review (7)Commentary (2)Editorial (1)Method (1) Facet Publication typeJournalScientific Reports (3)ACS Chemical Biology (2)Biochemical Society Transactions (2)Cell Reports (2)EMBO Journal (2)EMBO Reports (2)Frontiers in Molecular Biosciences (2)Journal of Biological Chemistry (2)Nature Communications (2)Biophysical Journal (1)Cell Chemical Biology (1)Cell Reports Physical Science (1)Frontiers in Molecular Neuroscience (1)Journal of the American Chemical Society (1)Life Science Alliance (1)Methods in Molecular Biology (1)Microbiology (1)Nature Chemical Biology (1)Nature Structural & Molecular Biology (1)Open Biology (1)PLOS ONE (1)RNA Biology (1)Royal Society Open Science (1)Science Signaling (1)Structure (1) Facet Journal Publications Displaying 1 - 20 of 35Last updated : 29 March 2024 02:11 It’s a TRIM-endous view from the top: the varied roles of TRIpartite Motif proteins in brain development and disease Authors (2)Jane DudleyKatrin Rittinger Frontiers in Molecular Neuroscience Published 5 December 2023 Crick labsKatrin RittingerFull details A chemoproteomic platform for selective deubiquitinase inhibitor discovery Authors (12)Rosa Cookson Aini Vuorinen Jonathan PettingerCassandra KennedyJoanna Kirkpatrick Rachel E Peltier-Heap[...]Bram SnijdersMark Skehel David HouseKatrin Rittinger Jacob T Bush Cell Reports Physical Science Published 18 October 2023 Crick labs/ facilitiesKatrin RittingerProteomicsFull details Speaking the host language: how Salmonella effector proteins manipulate the host Authors (8)Timesh Pillay Sahampath U Hettiarachchi Jiyao Gan Ines Diaz-Del-Olmo Xiu-Jun YuJanina MuenchTeresa Thurston Jaclyn S Pearson Microbiology Published 6 June 2023 Crick labsKatrin RittingerFull details Efficient ligand discovery using sulfur(VI) fluoride reactive fragments Authors (12) Arron Aatkar Aini Vuorinen Oliver E Longfield Katharine Gilbert Rachel Peltier-Heap Craig D Wagner[...]Katrin Rittinger Chun-Wa ChungDavid House Nicholas CO Tomkinson Jacob T Bush ACS Chemical Biology Published 15 September 2023 Crick labs/ facilitiesKatrin RittingerTranslation teamFull details Profiling sulfur(VI) fluorides as reactive functionalities for chemical biology tools and expansion of the ligandable proteome Authors (11) Katharine E Gilbert Aini Vuorinen Arron Aatkar Peter Pogány Jonathan Pettinger Emma K GrantJoanna KirkpatrickKatrin Rittinger David House Glenn A Burley Jacob T Bush ACS Chemical Biology Published 17 February 2023 Crick labs/ facilitiesKatrin RittingerProteomicsFull details Structural basis for ubiquitylation by HOIL-1 Authors (4) Qilong Wu Marios G KoliopoulosKatrin Rittinger Benjamin Stieglitz Frontiers in Molecular Biosciences Published 6 January 2023 Crick labs/ facilitiesKatrin RittingerStructural BiologyFull details Divergent self-association properties of paralogous proteins TRIM2 and TRIM3 regulate their E3 ligase activity Authors (4)Diego EspositoJane DudleyAcely Garza-GarciaKatrin Rittinger Nature Communications Published 8 December 2022 Crick labs/ facilitiesKatrin RittingerLuiz Pedro CarvalhoStructural BiologyMRC Biomedical NMR CentreFull details Targeting the ubiquitin system by fragment-based drug discovery Authors (3)Cassandra KennedyKatherine McPhieKatrin Rittinger Frontiers in Molecular Biosciences Published 27 September 2022 Crick labsKatrin RittingerFull details Characterisation of HOIP RBR E3 ligase conformational dynamics using integrative modelling Authors (4)Marius KausasDiego EspositoKatrin Rittinger Franca Fraternali Scientific Reports Published 8 September 2022 Crick labsKatrin RittingerFull details Does it take two to tango? RING domain self-association and activity in TRIM E3 ubiquitin ligases Authors (3)Filippo FiorentiniDiego EspositoKatrin Rittinger Biochemical Society Transactions Published 1 December 2020 Crick labsKatrin RittingerFull details Advanced rules of relays Authors (2) Sonja LorenzKatrin Rittinger Nature Chemical Biology Published 1 November 2020 Crick labsKatrin RittingerFull details Structural dynamics in the La-module of La-related proteins Authors (4) Javier Lizarrondo Anne-Catherine Dock-BregeonLuigi Martino Maria R Conte RNA Biology Published 18 March 2020 Crick labs/ facilitiesKatrin RittingerStructural BiologyFull details The parkin-coregulated gene product PACRG promotes TNF signaling by stabilizing LUBAC Authors (18) Jens Meschede Maria Šadić Nikolas Furthmann Tim Miedema Dominik A Sehr A Kathrin Müller-Rischart[...] Fumiyo Ikeda Katrin Marcus Liliana Schaefer Jörg Tatzelt Konstanze F Winklhofer Science Signaling Published 4 February 2020 Crick labsKatrin RittingerFull details Single-domain antibodies as crystallization chaperones to enable structure-based inhibitor development for RBR E3 ubiquitin ligases Authors (8)Yi-Chun TsaiKarl Johansson David Dixon Stephen Martin Chun-Wa Chung Jane ClarksonDavid HouseKatrin Rittinger Cell Chemical Biology Published 16 January 2020 Crick labs/ facilitiesKatrin RittingerStructural BiologyProteomicsFull details Characterisation of class VI TRIM RING domains: linking RING activity to C-terminal domain identity Authors (3)Rebecca StevensDiego EspositoKatrin Rittinger Life Science Alliance Published 1 June 2019 Crick labs/ facilitiesKatrin RittingerStructural BiologyMRC Biomedical NMR CentreFull details Fragment-based covalent ligand screening enables rapid discovery of inhibitors for the RBR E3 ubiquitin ligase HOIP Authors (11) Henrik JohanssonYi-Chun Tsai Ken Fantom Chun-Wa Chung Sandra Kümper Luigi Martino Daniel A Thomas H Christian Eberl Marcel MuelbaierDavid HouseKatrin Rittinger Journal of the American Chemical Society Published 18 January 2019 Crick labs/ facilitiesKatrin RittingerStructural BiologyFull details Structure-function analyses of the bacterial zinc metalloprotease effector protein GtgA uncovers key residues required for deactivating NF-κB Authors (4) Elliott JenningsDiego EspositoKatrin Rittinger Teresa LM Thurston Journal of Biological Chemistry Published 26 July 2018 Crick labs/ facilitiesKatrin RittingerStructural BiologyFull details Dynamic allostery in PLCγ1 and its modulation by a cancer mutation revealed by MD simulation and NMR Authors (6) H Koss TD BunneyDiego Esposito M Martins M KatanPaul Driscoll Biophysical Journal Published 3 July 2018 Crick labs/ facilitiesKatrin RittingerMetabolomicsMRC Biomedical NMR CentreFull details Molecular mechanism of influenza A NS1-mediated TRIM25 recognition and inhibition Authors (11) Marios G Koliopoulos Mathilde Lethier Annemarthe G van der Veen Kevin Haubrich Janosch Hennig Eva KowalinskiRebecca Stevens Stephen R MartinCaetano Reis e Sousa Stephen CusackKatrin Rittinger Nature Communications Published 8 May 2018 Crick labs/ facilitiesKatrin RittingerCaetano Reis e SousaStructural BiologyProteomicsFull details RBR ligase-mediated ubiquitin transfer: a tale with many twists and turns Authors (2) Helen WaldenKatrin Rittinger Nature Structural & Molecular Biology Published 7 May 2018 Crick labsKatrin RittingerFull details Pagination Current page 1 Page 2 Next page Next Last page Last Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
It’s a TRIM-endous view from the top: the varied roles of TRIpartite Motif proteins in brain development and disease Authors (2)Jane DudleyKatrin Rittinger Frontiers in Molecular Neuroscience Published 5 December 2023 Crick labsKatrin RittingerFull details
A chemoproteomic platform for selective deubiquitinase inhibitor discovery Authors (12)Rosa Cookson Aini Vuorinen Jonathan PettingerCassandra KennedyJoanna Kirkpatrick Rachel E Peltier-Heap[...]Bram SnijdersMark Skehel David HouseKatrin Rittinger Jacob T Bush Cell Reports Physical Science Published 18 October 2023 Crick labs/ facilitiesKatrin RittingerProteomicsFull details
Speaking the host language: how Salmonella effector proteins manipulate the host Authors (8)Timesh Pillay Sahampath U Hettiarachchi Jiyao Gan Ines Diaz-Del-Olmo Xiu-Jun YuJanina MuenchTeresa Thurston Jaclyn S Pearson Microbiology Published 6 June 2023 Crick labsKatrin RittingerFull details
Efficient ligand discovery using sulfur(VI) fluoride reactive fragments Authors (12) Arron Aatkar Aini Vuorinen Oliver E Longfield Katharine Gilbert Rachel Peltier-Heap Craig D Wagner[...]Katrin Rittinger Chun-Wa ChungDavid House Nicholas CO Tomkinson Jacob T Bush ACS Chemical Biology Published 15 September 2023 Crick labs/ facilitiesKatrin RittingerTranslation teamFull details
Profiling sulfur(VI) fluorides as reactive functionalities for chemical biology tools and expansion of the ligandable proteome Authors (11) Katharine E Gilbert Aini Vuorinen Arron Aatkar Peter Pogány Jonathan Pettinger Emma K GrantJoanna KirkpatrickKatrin Rittinger David House Glenn A Burley Jacob T Bush ACS Chemical Biology Published 17 February 2023 Crick labs/ facilitiesKatrin RittingerProteomicsFull details
Structural basis for ubiquitylation by HOIL-1 Authors (4) Qilong Wu Marios G KoliopoulosKatrin Rittinger Benjamin Stieglitz Frontiers in Molecular Biosciences Published 6 January 2023 Crick labs/ facilitiesKatrin RittingerStructural BiologyFull details
Divergent self-association properties of paralogous proteins TRIM2 and TRIM3 regulate their E3 ligase activity Authors (4)Diego EspositoJane DudleyAcely Garza-GarciaKatrin Rittinger Nature Communications Published 8 December 2022 Crick labs/ facilitiesKatrin RittingerLuiz Pedro CarvalhoStructural BiologyMRC Biomedical NMR CentreFull details
Targeting the ubiquitin system by fragment-based drug discovery Authors (3)Cassandra KennedyKatherine McPhieKatrin Rittinger Frontiers in Molecular Biosciences Published 27 September 2022 Crick labsKatrin RittingerFull details
Characterisation of HOIP RBR E3 ligase conformational dynamics using integrative modelling Authors (4)Marius KausasDiego EspositoKatrin Rittinger Franca Fraternali Scientific Reports Published 8 September 2022 Crick labsKatrin RittingerFull details
Does it take two to tango? RING domain self-association and activity in TRIM E3 ubiquitin ligases Authors (3)Filippo FiorentiniDiego EspositoKatrin Rittinger Biochemical Society Transactions Published 1 December 2020 Crick labsKatrin RittingerFull details
Advanced rules of relays Authors (2) Sonja LorenzKatrin Rittinger Nature Chemical Biology Published 1 November 2020 Crick labsKatrin RittingerFull details
Structural dynamics in the La-module of La-related proteins Authors (4) Javier Lizarrondo Anne-Catherine Dock-BregeonLuigi Martino Maria R Conte RNA Biology Published 18 March 2020 Crick labs/ facilitiesKatrin RittingerStructural BiologyFull details
The parkin-coregulated gene product PACRG promotes TNF signaling by stabilizing LUBAC Authors (18) Jens Meschede Maria Šadić Nikolas Furthmann Tim Miedema Dominik A Sehr A Kathrin Müller-Rischart[...] Fumiyo Ikeda Katrin Marcus Liliana Schaefer Jörg Tatzelt Konstanze F Winklhofer Science Signaling Published 4 February 2020 Crick labsKatrin RittingerFull details
Single-domain antibodies as crystallization chaperones to enable structure-based inhibitor development for RBR E3 ubiquitin ligases Authors (8)Yi-Chun TsaiKarl Johansson David Dixon Stephen Martin Chun-Wa Chung Jane ClarksonDavid HouseKatrin Rittinger Cell Chemical Biology Published 16 January 2020 Crick labs/ facilitiesKatrin RittingerStructural BiologyProteomicsFull details
Characterisation of class VI TRIM RING domains: linking RING activity to C-terminal domain identity Authors (3)Rebecca StevensDiego EspositoKatrin Rittinger Life Science Alliance Published 1 June 2019 Crick labs/ facilitiesKatrin RittingerStructural BiologyMRC Biomedical NMR CentreFull details
Fragment-based covalent ligand screening enables rapid discovery of inhibitors for the RBR E3 ubiquitin ligase HOIP Authors (11) Henrik JohanssonYi-Chun Tsai Ken Fantom Chun-Wa Chung Sandra Kümper Luigi Martino Daniel A Thomas H Christian Eberl Marcel MuelbaierDavid HouseKatrin Rittinger Journal of the American Chemical Society Published 18 January 2019 Crick labs/ facilitiesKatrin RittingerStructural BiologyFull details
Structure-function analyses of the bacterial zinc metalloprotease effector protein GtgA uncovers key residues required for deactivating NF-κB Authors (4) Elliott JenningsDiego EspositoKatrin Rittinger Teresa LM Thurston Journal of Biological Chemistry Published 26 July 2018 Crick labs/ facilitiesKatrin RittingerStructural BiologyFull details
Dynamic allostery in PLCγ1 and its modulation by a cancer mutation revealed by MD simulation and NMR Authors (6) H Koss TD BunneyDiego Esposito M Martins M KatanPaul Driscoll Biophysical Journal Published 3 July 2018 Crick labs/ facilitiesKatrin RittingerMetabolomicsMRC Biomedical NMR CentreFull details
Molecular mechanism of influenza A NS1-mediated TRIM25 recognition and inhibition Authors (11) Marios G Koliopoulos Mathilde Lethier Annemarthe G van der Veen Kevin Haubrich Janosch Hennig Eva KowalinskiRebecca Stevens Stephen R MartinCaetano Reis e Sousa Stephen CusackKatrin Rittinger Nature Communications Published 8 May 2018 Crick labs/ facilitiesKatrin RittingerCaetano Reis e SousaStructural BiologyProteomicsFull details
RBR ligase-mediated ubiquitin transfer: a tale with many twists and turns Authors (2) Helen WaldenKatrin Rittinger Nature Structural & Molecular Biology Published 7 May 2018 Crick labsKatrin RittingerFull details