Publications

The molecular evolution of vertebrate organs

Authors (1)

Margarida Cardoso Moreira

Nature Ecology and Evolution

Published 1 April 2026

Crick labs

Margarida Cardoso-Moreira

Full details

The evolution of gene regulation in mammalian cerebellum development

Authors (27)

Ioannis Sarropoulos
Mari Sepp
Tetsuya Yamada
Philipp SL Schäfer
Nils Trost
Julia Schmidt
[...]
Lena M Kutscher
Rüdiger Behr
Stefan M Pfister
Stein Aerts
Henrik Kaessmann

Science

Published 29 January 2026

Crick labs

Margarida Cardoso-Moreira

Full details

The origin and molecular evolution of the mammalian liver cell architecture

Preprint

Authors (21)

Xuefei Yuan
Leticia Rodríguez-Montes
Bastienne Zaremba
Nils Trost
Céline Schneider
Julia Schmidt
[...]
Athanasia C Tzika
Michel C Milinkovitch
Svante Pääbo
Margarida Cardoso Moreira
Henrik Kaessmann

bioRxiv

Published 14 October 2025

Crick labs

Margarida Cardoso-Moreira

Full details

A male-essential miRNA is key for avian sex chromosome dosage compensation

Authors (24)

Amir Fallahshahroudi
Sara Yousefi Taemeh
Leticia Rodríguez-Montes
Nils Trost
Dana Frank
Pascal Lafrenz
[...]
Guenter Kramer
Carl-Johan Rubin
Margarida Cardoso Moreira
Mike J McGrew
Henrik Kaessmann

Nature

Published 4 September 2025

Crick labs

Margarida Cardoso-Moreira

Full details

The evolution of gene regulatory programs controlling gonadal development in primates

Preprint

Authors (15)

Nils Trost
Amir Fallahshahroudi
Ioannis Sarropoulos
Céline Schneider
Julia Schmidt
Noe Mbengue
[...]
Florent Murat
Mari Sepp
Margarida Cardoso Moreira
Rüdiger Behr
Henrik Kaessmann

bioRxiv

Published 19 June 2025

Crick labs

Margarida Cardoso-Moreira

Full details

Cellular development and evolution of the mammalian cerebellum

Authors (22)

Mari Sepp
Kevin Leiss
Florent Murat
Konstantin Okonechnikov
Piyush Joshi
Evgeny Leushkin
[...]
Simon Anders
Margarida Cardoso Moreira
Ioannis Sarropoulos
Stefan M Pfister
Henrik Kaessmann

Nature

Published 25 January 2024

Crick labs

Margarida Cardoso-Moreira

Full details

Sex-biased gene expression across mammalian organ development and evolution

Authors (8)

Leticia Rodríguez-Montes
Svetlana Ovchinnikova
Xuefei Yuan
Tania Studer
Ioannis Sarropoulos
Simon Anders
Henrik Kaessmann
Margarida Cardoso Moreira

Science

Published 3 November 2023

Crick labs

Margarida Cardoso-Moreira

Full details

Single-nucleus RNA-seq of adult female and male mouse livers for sex-biased gene expression analyses

Authors (1)

Margarida Cardoso Moreira

BioStudies

Published 3 August 2023

Crick labs

Margarida Cardoso-Moreira

Full details

Zenodo deposit: Analysis code for Sex-biased gene expression across mammalian organ development and evolution

Authors (1)

Margarida Cardoso Moreira

Zenodo

Published 31 July 2023

Crick labs

Margarida Cardoso-Moreira

Full details

The molecular evolution of spermatogenesis across mammals

Authors (24)

Florent Murat
Noe Mbengue
Sofia Boeg Winge
Timo Trefzer
Evgeny Leushkin
Mari Sepp
[...]
Tomas Marques-Bonet
Frank Grützner
Kristian Almstrup
Mikkel Heide Schierup
Henrik Kaessmann

Nature

Published 12 January 2023

Crick labs

Margarida Cardoso-Moreira

Full details

NIMA-related kinase 9 regulates the phosphorylation of the essential myosin light chain in the heart

Authors (26)

Marion Müller
Rose Eghbalian
Jes-Niels Boeckel
Karen S Frese
Jan Haas
Elham Kayvanpour
[...]
Henrik Kaessmann
Hugo A Katus
Norbert Frey
Lars M Steinmetz
Benjamin Meder

Nature Communications

Published 20 October 2022

Crick labs

Margarida Cardoso-Moreira

Full details

ExoPLOT: Representation of alternative splicing in human tissues and developmental stages with transposed element (TE) involvement

Authors (6)

Fengjun Zhang
Carsten Alexander Raabe
Margarida Cardoso Moreira
Jürgen Brosius
Henrik Kaessmann
Jürgen Schmitz

Genomics

Published 1 July 2022

Crick labs

Margarida Cardoso-Moreira

Full details

TRIM7 restricts Coxsackievirus and norovirus infection by detecting the C-terminal glutamine generated by 3C protease processing

Preprint

Authors (9)

Jakub Luptak
Donna Mallery
Aminu S Jahun
Anna Albecka
Dean Clift
Osaid Ather
Greg Slodkowicz
Ian Goodfellow
Leo James

bioRxiv

Published 5 July 2022

Crick labs

Margarida Cardoso-Moreira

Full details

Developmental and evolutionary dynamics of cis-regulatory elements in mouse cerebellar cells

Authors (13)

Ioannis Sarropoulos
Mari Sepp
Robert Frömel
Kevin Leiss
Nils Trost
Evgeny Leushkin
[...]
Peter Giere
Lena M Kutscher
Margarida Cardoso Moreira
Stefan M Pfister
Henrik Kaessmann

Science

Published 27 August 2021

Crick labs

Margarida Cardoso-Moreira

Full details

Alternative splicing during mammalian organ development

Authors (4)

Pavel V Mazin
Philipp Khaitovich
Margarida Cardoso Moreira
Henrik Kaessmann

Nature Genetics

Published 1 June 2021

Crick labs

Margarida Cardoso-Moreira

Full details

Transcriptome and translatome co-evolution in mammals

Authors (17)

Zhong-Yi Wang
Evgeny Leushkin
Angélica Liechti
Svetlana Ovchinnikova
Katharina Mößinger
Thoomke Brüning
[...]
Bernard de Massy
Mark E Gill
Antoine HFM Peters
Simon Anders
Henrik Kaessmann

Nature

Published 24 December 2020

Crick labs

Margarida Cardoso-Moreira

Full details

Developmental gene expression differences between humans and mammalian models

Authors (7)

Margarida Cardoso Moreira
Ioannis Sarropoulos
Britta Velten
Matthew Mort
David N Cooper
Wolfgang Huber
Henrik Kaessmann

Cell Reports

Published 27 October 2020

Crick labs

Margarida Cardoso-Moreira

Full details

Developmental dynamics of lncRNAs across mammalian organs and species

Authors (4)

Ioannis Sarropoulos
Ray Marin
Margarida Cardoso Moreira
Henrik Kaessmann

Nature

Published 25 July 2019

Crick labs

Margarida Cardoso-Moreira

Full details

Gene expression across mammalian organ development

Authors (33)

Margarida Cardoso Moreira
Jean Halbert
Delphine Valloton
Britta Velten
Chunyan Chen
Yi Shao
[...]
Wolfgang Huber
Julie Baker
Simon Anders
Yong E Zhang
Henrik Kaessmann

Nature

Published 1 July 2019

Crick labs

Full details

Investigating human placentation and pregnancy using first trimester chorionic villi

Authors (10)

Roberta L Hannibal
Margarida Cardoso Moreira
Shilpa P Chetty
Joanne Lau
Zhongxia Qi
Eduardo Gonzalez-Maldonado
Athena M Cherry
Jingwei Yu
Mary E Norton
Julie C Baker

Placenta

Published 1 May 2018

Crick labs

Margarida Cardoso-Moreira

Full details

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: Publications

Lab content

The molecular evolution of vertebrate organs

The evolution of gene regulation in mammalian cerebellum development

The origin and molecular evolution of the mammalian liver cell architecture

A male-essential miRNA is key for avian sex chromosome dosage compensation

The evolution of gene regulatory programs controlling gonadal development in primates

Cellular development and evolution of the mammalian cerebellum

Sex-biased gene expression across mammalian organ development and evolution

Single-nucleus RNA-seq of adult female and male mouse livers for sex-biased gene expression analyses

Zenodo deposit: Analysis code for Sex-biased gene expression across mammalian organ development and evolution

The molecular evolution of spermatogenesis across mammals

NIMA-related kinase 9 regulates the phosphorylation of the essential myosin light chain in the heart

ExoPLOT: Representation of alternative splicing in human tissues and developmental stages with transposed element (TE) involvement

TRIM7 restricts Coxsackievirus and norovirus infection by detecting the C-terminal glutamine generated by 3C protease processing

Developmental and evolutionary dynamics of cis-regulatory elements in mouse cerebellar cells

Alternative splicing during mammalian organ development

Transcriptome and translatome co-evolution in mammals

Developmental gene expression differences between humans and mammalian models

Developmental dynamics of lncRNAs across mammalian organs and species

Gene expression across mammalian organ development

Investigating human placentation and pregnancy using first trimester chorionic villi

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Research partnerships

PhD students

We Go Way Back

About us

The Crick magazine

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Publications

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