Publications

Vitamin B5 supports MYC oncogenic metabolism and tumor progression in breast cancer

Authors (40)

Peter Kreuzaler
Paolo Inglese
Avinash Ghanate
Ersa Gjelaj
Vincen Wu
Yulia Panina
[...]
George Poulogiannis
Greg McMahon
Zoltan Takats
Josephine Bunch
Mariia Yuneva

Nature Metabolism

Published 1 November 2023

Crick labs/ facilities

Full details

Metabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeutic target

Authors (54)

Johan Vande Voorde
Rory T Steven
Arafath K Najumudeen
Catriona A Ford
Alex Dexter
Ariadna Gonzalez-Fernandez
[...]
David Sumpton
Zoltan Takats
Andrew D Campbell
Josephine Bunch
Owen J Sansom

Nature Metabolism

Published 1 August 2023

Crick labs/ facilities

Full details

ALDH1L2 regulation of formate, formyl-methionine, and ROS controls cancer cell migration and metastasis

Authors (20)

Cell Reports

Published 26 May 2023

Crick labs/ facilities

Full details

Cold exposure as anti-cancer therapy

Authors (1)

Mariia Yuneva

Cancer Cell

Published 10 October 2022

Crick labs

Mariia Yuneva

Full details

[18F]-(2S,4R)4-fluoroglutamine PET imaging of glutamine metabolism in murine models of hepatocellular carcinoma (HCC)

Authors (6)

Youngho Seo
Miranda C Craig
Stephanie T Murphy
Jinjin Feng
Xin Chen
Mariia Yuneva

Molecular Imaging

Published 25 July 2022

Crick labs

Mariia Yuneva

Full details

Dinner is served, sir: Fighting cancer with the right diet

Authors (2)

Andrés Méndez-Lucas
Mariia Yuneva

Cell

Published 22 December 2021

Crick labs

Mariia Yuneva

Full details

Constitutive activation of the PI3K-Akt-mTORC1 pathway sustains the m.3243 A > G mtDNA mutation

Authors (13)

Chih-Yao Chung
Kritarth Singh
Vassilios N Kotiadis
Gabriel E Valdebenito
Jee Hwan Ahn
Emilie Topley
[...]
Benoit Bilanges
Robert DS Pitceathly
Gyorgy Szabadkai
Mariia Yuneva
Michael R Duchen

Nature Communications

Published 4 November 2021

Crick labs/ facilities

Full details

Cysteine and folate metabolism are targetable vulnerabilities of metastatic colorectal cancer

Authors (13)

Josep Tarrago Celada
Carles Foguet
Míriam Tarrado-Castellarnau
Silvia Marin
Xavier Hernández-Alias
Jordi Perarnau
[...]
Roger R Gomis
Eytan Ruppin
Mariia Yuneva
Pedro de Atauri
Marta Cascante

Cancers

Published 23 January 2021

Crick labs

Mariia Yuneva

Full details

The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancer

Authors (93)

AK Najumudeen
F Ceteci
SK Fey
G Hamm
RT Steven
H Hall
[...]
RJA Goodwin
J Bunch
M Bushell
AD Campbell
OJ Sansom

Nature Genetics

Published 1 January 2021

Crick labs

Mariia Yuneva

Full details

Identifying strategies to target the metabolic flexibility of tumours

Authors (16)

Nature Metabolism

Published 1 April 2020

Crick labs/ facilities

Full details

Defining a metabolic landscape of tumours: genome meets metabolism

Authors (4)

British Journal of Cancer

Published 21 January 2020

Crick labs

Mariia Yuneva

Full details

Adapt and conquer: Metabolic flexibility in cancer growth, invasion and evasion

Authors (4)

Peter Kreuzaler
Yulia Panina
Joanna Segal
Mariia Yuneva

Molecular Metabolism

Published 1 March 2020

Crick labs

Mariia Yuneva

Full details

Metabolic reprogramming and Notch activity distinguish between non-small cell lung cancer subtypes

Authors (13)

Katherine Sellers
Thaddeus D Allen
Michael Bousamra
JinLian Tan
Andres Mendez-Lucas
Wei Lin
[...]
James Macrae
Richard M Higashi
Andrew N Lane
Teresa W-M Fan
Mariia Yuneva

British Journal of Cancer

Published 1 July 2019

Crick labs/ facilities

Full details

Low catalytic activity is insufficient to induce disease pathology in triosephosphate isomerase deficiency

Authors (32)

Joanna Segal
Michael Muelleder
Antje Krüger
Thure Adler
Manuela Scholze-Wittler
Lore Becker
[...]
Helmut Fuchs
Martin H de Angelis
Heinrich Schrewe
Mariia Yuneva
Markus Ralser

Journal of Inherited Metabolic Disease

Published 1 September 2019

Crick labs/ facilities

Full details

Hyperpolarised 13C MRI: a new horizon for non-invasive diagnosis of aggressive breast cancer

Authors (24)

Oshaani Abeyakoon
Arash Latifoltojar
Fiona Gong
Marianthi-Vasiliki Papoutsaki
Rafat Chowdhury
Matthias Glaser
[...]
Rob Stein
Mariia Yuneva
Gyorgi Szabadkai
Steve Halligan
Shonit Punwani

BJR Case Reports

Published 1 September 2019

Crick labs

Mariia Yuneva

Full details

Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity

Authors (46)

Kim Vriens
Stefan Christen
Sweta Parik
Dorien Broekaert
Kazuaki Yoshinaga
Ali Talebi
[...]
Chris Verslype
Sven Christian
Sylvia Grünewald
Thomas GP Grünewald
Sarah-Maria Fendt

Nature

Published 6 February 2019

Crick labs

Mariia Yuneva

Full details

The big picture: exploring the metabolic cross-talk in cancer

Authors (2)

Almut Schulze
Mariia Yuneva

Disease Models & Mechanisms

Published 1 August 2018

Crick labs

Mariia Yuneva

Full details

De novo MYC addiction as an adaptive response of cancer cells to CDK4/6 inhibition

Authors (7)

Míriam Tarrado-Castellarnau
Pedro de Atauri
Josep Tarrago Celada
Jordi Perarnau
Mariia Yuneva
Timothy M Thomson
Marta Cascante

Molecular Systems Biology

Published 1 October 2017

Crick labs

Mariia Yuneva

Full details

Glucose catabolism in liver tumors induced by c-MYC can be sustained by various PKM1/PKM2 ratios and pyruvate kinase activities

Authors (13)

Andres Mendez-Lucas
Xiaolei Li
Junjie Hu
Li Che
Xinhua Song
Jiaoyuan Jia
[...]
Paul Driscoll
Darjus F Tschaharganeh
Diego F Calvisi
Mariia Yuneva
Xin Chen

Cancer Research

Published 1 August 2017

Crick labs/ facilities

Full details

Hopefully devoted to Q: targeting glutamine addiction in cancer

Authors (2)

Emma R Still
Mariia Yuneva

British Journal of Cancer

Published 25 April 2017

Crick labs

Mariia Yuneva

Full details

Research case studies

Postdoctoral clinical fellows

Hello Brain!

News and reports

About us

Yuneva lab
Oncogenes and Tumour Metabolism Laboratory
: Publications

Lab content

Publications

Year published

Research topics

Publication type

Journal

Vitamin B5 supports MYC oncogenic metabolism and tumor progression in breast cancer

Metabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeutic target

ALDH1L2 regulation of formate, formyl-methionine, and ROS controls cancer cell migration and metastasis

Cold exposure as anti-cancer therapy

[18F]-(2S,4R)4-fluoroglutamine PET imaging of glutamine metabolism in murine models of hepatocellular carcinoma (HCC)

Dinner is served, sir: Fighting cancer with the right diet

Constitutive activation of the PI3K-Akt-mTORC1 pathway sustains the m.3243 A > G mtDNA mutation

Cysteine and folate metabolism are targetable vulnerabilities of metastatic colorectal cancer

The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancer

Identifying strategies to target the metabolic flexibility of tumours

Defining a metabolic landscape of tumours: genome meets metabolism

Adapt and conquer: Metabolic flexibility in cancer growth, invasion and evasion

Metabolic reprogramming and Notch activity distinguish between non-small cell lung cancer subtypes

Low catalytic activity is insufficient to induce disease pathology in triosephosphate isomerase deficiency

Hyperpolarised 13C MRI: a new horizon for non-invasive diagnosis of aggressive breast cancer

Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity

The big picture: exploring the metabolic cross-talk in cancer

De novo MYC addiction as an adaptive response of cancer cells to CDK4/6 inhibition

Glucose catabolism in liver tumors induced by c-MYC can be sustained by various PKM1/PKM2 ratios and pyruvate kinase activities

Hopefully devoted to Q: targeting glutamine addiction in cancer

The Francis Crick Institute is a unique partnership between

Research case studies

Postdoctoral clinical fellows

Hello Brain!

News and reports

About us

Lab content

Publications

Year published

Research topics

Publication type

Journal

Publications

Share the page

The Francis Crick Institute is a unique partnership between