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Breadcrumb Mariya Moosajee Moosajee lab Ocular Genomics and Therapeutics Laboratory : Publications Lab contentLab contentIn this section Overview Vacancies Members Areas of interest Publications PublicationsCrick/Pre-CrickCrick publications (46)Pre-Crick publications (73) Facet Crick/Pre-Crick Publications Displaying 1 - 20 of 119Last updated : 30 November 2023 02:38 Loss of REP1 impacts choroidal melanogenesis and vasculogenesis in choroideremia Authors (8) Hajrah Sakar Dhani Tracey-White Ahmed M Hagag Thomas Burgoyne Neelima Nair Lasse D Jensen Malia M EdwardsMariya Moosajee BBA: Molecular Basis of Disease Published 20 November 2023 Crick labsMariya MoosajeeFull details Longitudinal structure-function analysis of molecularly-confirmed CYP4V2 Bietti Crystalline Dystrophy Authors (4) Riccardo Cheloni Neil Clough Daniel JacksonMariya Moosajee Eye Published 28 October 2023 Crick labsMariya MoosajeeFull details Identification of the regulatory circuit governing corneal epithelial fate determination and disease Authors (17) Jos GA Smits Dulce Lima Cunha Maryam Amini Marina Bertolin Camille Laberthonnière Jieqiong Qu[...]Mariya Moosajee Daniel Aberdam Nora Szentmary Simon J van Heeringen Huiqing Zhou PLOS Biology Published 19 October 2023 Crick labsMariya MoosajeeFull details Gene augmentation of CHM using non-viral episomal vectors in models of choroideremia Authors (5)Lyes Toualbi Maria Toms Patrick Vingadas Almeida Richard HarbottleMariya Moosajee International Journal of Molecular Sciences Published 16 October 2023 Crick labsMariya MoosajeeFull details Foveal hypoplasia in CRB1-related retinopathies Authors (9) Ana Catalina Rodriguez-Martinez Bethany Elora Higgins Vijay Tailor-Hamblin Samantha Malka Riccardo Cheloni Alexander Mark Collins John Bladen Robert HendersonMariya Moosajee International Journal of Molecular Sciences Published 11 September 2023 Crick labsMariya MoosajeeFull details Oxidative and endoplasmic reticulum stress represent novel therapeutic targets for choroideremia Authors (4)Hajrah Sarkar Manuela Lahne Neelima NairMariya Moosajee Antioxidants Published 30 August 2023 Crick labsMariya MoosajeeFull details The genetic determinants of axial length: From microphthalmia to high myopia in childhood Authors (2) Daniel JacksonMariya Moosajee Annual Review of Genomics and Human Genetics Published 1 August 2023 Crick labsMariya MoosajeeFull details Restoration of functional PAX6 in aniridia patient iPSC-derived ocular tissue models using repurposed nonsense suppression drugs Authors (6) Dulce Lima CunhaHajrah Sarkar Jonathan Eintracht Philippa Harding Jo Huiqing ZhouMariya Moosajee Molecular Therapy : Nucleic Acids Published 12 September 2023 Crick labsMariya MoosajeeFull details Nuclear receptor subfamily 2 group E member 3 (NR2E3): Role in retinal development and disease Authors (3) Maria Toms Natasha WardMariya Moosajee Genes Published 23 June 2023 Crick labsMariya MoosajeeFull details Successful large gene augmentation of USH2A with non-viral episomal vectors Authors (5) Maria TomsLyes Toualbi Patrick V Almeida Richard HarbottleMariya Moosajee Molecular Therapy Published 6 September 2023 Crick labs/ facilitiesMariya MoosajeeBiological Research FacilityFull details Establishment and characterization of an iPSC line (UCLi023-A) derived from a Late-Onset Retinal Degeneration patient carrying a founder mutation in C1QTNF5 Authors (5) Ana Alonso-Carriazo Fernández Phoebe Ashley-Norman Zaynab ButtMariya Moosajee Amanda-Jayne Francis Carr Stem Cell Research Published 1 June 2023 Crick labsMariya MoosajeeFull details OPA1 dominant optic atrophy: Pathogenesis and therapeutic targets Authors (7) David CS Wong Joshua P Harvey Neringa Jurkute Sara M ThomasyMariya Moosajee Patrick Yu-Wai-Man Michael J Gilhooley Journal of Neuro-Ophthalmology Published 1 December 2023 Crick labsMariya MoosajeeFull details Identification of novel coloboma candidate genes through conserved gene expression analyses across four vertebrate species Authors (7) Violeta Trejo-RevelesNicholas Owen Brian Ho Ching Chan Maria Toms Jeffrey J SchoenebeckMariya Moosajee Joe Rainger Biomolecules Published 4 February 2023 Crick labsMariya MoosajeeFull details Loss of the crumbs cell polarity complex disrupts epigenetic transcriptional control and cell cycle progression in the developing retina Authors (10)Nicholas Owen Maria Toms Yuan TianLyes Toualbi Rose Richardson Rodrigo Young Dhani Tracey-White Pawan Dhami Stephan BeckMariya Moosajee Journal of Pathology Published 1 April 2023 Crick labsMariya MoosajeeFull details PAX6 disease models for aniridia Authors (4) Dorsa Abdolkarimi Dulce Lima Cunha Manuela LahneMariya Moosajee Indian Journal of Ophthalmology Published 1 December 2022 Crick labsMariya MoosajeeFull details A natural history study of RP2-related retinopathy Authors (3) Riccardo Cheloni Daniel JacksonMariya Moosajee Journal of Clinical Medicine Published 22 November 2022 Crick labsMariya MoosajeeFull details Changes in mitochondrial size and morphology in the RPE and photoreceptors of the developing and ageing zebrafish Authors (6) Thomas Burgoyne Maria Toms Chris Way Dhani Tracey-White Clare E FutterMariya Moosajee Cells Published 9 November 2022 Crick labsMariya MoosajeeFull details Impact of the COVID-19 pandemic on the research activities of UK ophthalmologists Authors (5) HDJ Hogg L Low JE Self Royal College of Ophthalmologists’ Academic and Research Subcommittee JS Rahi Eye Published 1 July 2023 Crick labsMariya MoosajeeFull details Real-world clinical and molecular management of 50 prospective patients with microphthalmia, anophthalmia and/or ocular coloboma Authors (6) Philippa Harding Sri Gore Samantha Malka Jayashree Rajkumar Ngozi OluonyeMariya Moosajee British Journal of Ophthalmology Published 1 December 2023 Crick labsMariya MoosajeeFull details Prospective study of pediatric patients presenting with idiopathic infantile nystagmus-Management and molecular diagnostics Authors (8) Nancy Aychoua Elena Schiff Samantha Malka Vijay K Tailor Hwei Wuen Chan Ngozi Oluonye Maria TheodorouMariya Moosajee Frontiers in Genetics Published 22 August 2022 Crick labsMariya MoosajeeFull details Pagination Current page 1 Page 2 Page 3 Page 4 Page 5 Page 6 Next page Next Last page Last Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Loss of REP1 impacts choroidal melanogenesis and vasculogenesis in choroideremia Authors (8) Hajrah Sakar Dhani Tracey-White Ahmed M Hagag Thomas Burgoyne Neelima Nair Lasse D Jensen Malia M EdwardsMariya Moosajee BBA: Molecular Basis of Disease Published 20 November 2023 Crick labsMariya MoosajeeFull details
Longitudinal structure-function analysis of molecularly-confirmed CYP4V2 Bietti Crystalline Dystrophy Authors (4) Riccardo Cheloni Neil Clough Daniel JacksonMariya Moosajee Eye Published 28 October 2023 Crick labsMariya MoosajeeFull details
Identification of the regulatory circuit governing corneal epithelial fate determination and disease Authors (17) Jos GA Smits Dulce Lima Cunha Maryam Amini Marina Bertolin Camille Laberthonnière Jieqiong Qu[...]Mariya Moosajee Daniel Aberdam Nora Szentmary Simon J van Heeringen Huiqing Zhou PLOS Biology Published 19 October 2023 Crick labsMariya MoosajeeFull details
Gene augmentation of CHM using non-viral episomal vectors in models of choroideremia Authors (5)Lyes Toualbi Maria Toms Patrick Vingadas Almeida Richard HarbottleMariya Moosajee International Journal of Molecular Sciences Published 16 October 2023 Crick labsMariya MoosajeeFull details
Foveal hypoplasia in CRB1-related retinopathies Authors (9) Ana Catalina Rodriguez-Martinez Bethany Elora Higgins Vijay Tailor-Hamblin Samantha Malka Riccardo Cheloni Alexander Mark Collins John Bladen Robert HendersonMariya Moosajee International Journal of Molecular Sciences Published 11 September 2023 Crick labsMariya MoosajeeFull details
Oxidative and endoplasmic reticulum stress represent novel therapeutic targets for choroideremia Authors (4)Hajrah Sarkar Manuela Lahne Neelima NairMariya Moosajee Antioxidants Published 30 August 2023 Crick labsMariya MoosajeeFull details
The genetic determinants of axial length: From microphthalmia to high myopia in childhood Authors (2) Daniel JacksonMariya Moosajee Annual Review of Genomics and Human Genetics Published 1 August 2023 Crick labsMariya MoosajeeFull details
Restoration of functional PAX6 in aniridia patient iPSC-derived ocular tissue models using repurposed nonsense suppression drugs Authors (6) Dulce Lima CunhaHajrah Sarkar Jonathan Eintracht Philippa Harding Jo Huiqing ZhouMariya Moosajee Molecular Therapy : Nucleic Acids Published 12 September 2023 Crick labsMariya MoosajeeFull details
Nuclear receptor subfamily 2 group E member 3 (NR2E3): Role in retinal development and disease Authors (3) Maria Toms Natasha WardMariya Moosajee Genes Published 23 June 2023 Crick labsMariya MoosajeeFull details
Successful large gene augmentation of USH2A with non-viral episomal vectors Authors (5) Maria TomsLyes Toualbi Patrick V Almeida Richard HarbottleMariya Moosajee Molecular Therapy Published 6 September 2023 Crick labs/ facilitiesMariya MoosajeeBiological Research FacilityFull details
Establishment and characterization of an iPSC line (UCLi023-A) derived from a Late-Onset Retinal Degeneration patient carrying a founder mutation in C1QTNF5 Authors (5) Ana Alonso-Carriazo Fernández Phoebe Ashley-Norman Zaynab ButtMariya Moosajee Amanda-Jayne Francis Carr Stem Cell Research Published 1 June 2023 Crick labsMariya MoosajeeFull details
OPA1 dominant optic atrophy: Pathogenesis and therapeutic targets Authors (7) David CS Wong Joshua P Harvey Neringa Jurkute Sara M ThomasyMariya Moosajee Patrick Yu-Wai-Man Michael J Gilhooley Journal of Neuro-Ophthalmology Published 1 December 2023 Crick labsMariya MoosajeeFull details
Identification of novel coloboma candidate genes through conserved gene expression analyses across four vertebrate species Authors (7) Violeta Trejo-RevelesNicholas Owen Brian Ho Ching Chan Maria Toms Jeffrey J SchoenebeckMariya Moosajee Joe Rainger Biomolecules Published 4 February 2023 Crick labsMariya MoosajeeFull details
Loss of the crumbs cell polarity complex disrupts epigenetic transcriptional control and cell cycle progression in the developing retina Authors (10)Nicholas Owen Maria Toms Yuan TianLyes Toualbi Rose Richardson Rodrigo Young Dhani Tracey-White Pawan Dhami Stephan BeckMariya Moosajee Journal of Pathology Published 1 April 2023 Crick labsMariya MoosajeeFull details
PAX6 disease models for aniridia Authors (4) Dorsa Abdolkarimi Dulce Lima Cunha Manuela LahneMariya Moosajee Indian Journal of Ophthalmology Published 1 December 2022 Crick labsMariya MoosajeeFull details
A natural history study of RP2-related retinopathy Authors (3) Riccardo Cheloni Daniel JacksonMariya Moosajee Journal of Clinical Medicine Published 22 November 2022 Crick labsMariya MoosajeeFull details
Changes in mitochondrial size and morphology in the RPE and photoreceptors of the developing and ageing zebrafish Authors (6) Thomas Burgoyne Maria Toms Chris Way Dhani Tracey-White Clare E FutterMariya Moosajee Cells Published 9 November 2022 Crick labsMariya MoosajeeFull details
Impact of the COVID-19 pandemic on the research activities of UK ophthalmologists Authors (5) HDJ Hogg L Low JE Self Royal College of Ophthalmologists’ Academic and Research Subcommittee JS Rahi Eye Published 1 July 2023 Crick labsMariya MoosajeeFull details
Real-world clinical and molecular management of 50 prospective patients with microphthalmia, anophthalmia and/or ocular coloboma Authors (6) Philippa Harding Sri Gore Samantha Malka Jayashree Rajkumar Ngozi OluonyeMariya Moosajee British Journal of Ophthalmology Published 1 December 2023 Crick labsMariya MoosajeeFull details
Prospective study of pediatric patients presenting with idiopathic infantile nystagmus-Management and molecular diagnostics Authors (8) Nancy Aychoua Elena Schiff Samantha Malka Vijay K Tailor Hwei Wuen Chan Ngozi Oluonye Maria TheodorouMariya Moosajee Frontiers in Genetics Published 22 August 2022 Crick labsMariya MoosajeeFull details