Publications

ATG7 and ATG14 restrict cytosolic and phagosomal Mycobacterium tuberculosis replication in human macrophages

Authors (9)

Nature Microbiology

Published 1 May 2023

Crick labs/ facilities

Full details

A terpene nucleoside from M. tuberculosis induces lysosomal lipid storage in foamy macrophages

Authors (23)

Melissa Bedard
Sanne van der Niet
Elliott Bernard
Gregory Babunovic
Tan-Yun Cheng
Beren Aylan
[...]
Joseph Keane
Sho Yamasaki
Maximiliano Gutierrez
Nicole van der Wel
D Branch Moody

Journal of Clinical Investigation

Published 15 March 2023

Crick labs

Maximiliano Gutierrez

Full details

High content quantitative imaging of Mycobacterium tuberculosis responses to acidic microenvironments within human macrophages

Authors (4)

FEBS Open Bio

Published 15 December 2022

Crick labs/ facilities

Full details

Lysosomal damage drives mitochondrial proteome remodelling and reprograms macrophage immunometabolism

Authors (17)

Nature Communications

Published 28 November 2022

Crick labs/ facilities

Full details

Intracellular niche switching as host subversion strategy of bacterial pathogens

Authors (2)

Maximiliano Gutierrez
Jost Enninga

Current Opinion in Cell Biology

Published 1 June 2022

Crick labs

Maximiliano Gutierrez

Full details

Visualizing pyrazinamide action by live single-cell imaging of phagosome acidification and Mycobacterium tuberculosis pH homeostasis

Authors (8)

mBio

Published 1 April 2022

Crick labs

Maximiliano Gutierrez

Full details

Cell wall architecture and function in microbial physiology

Authors (1)

Pierre Santucci

Molecular Microbiology

Published 1 April 2022

Crick labs

Maximiliano Gutierrez

Full details

A sandPIT for Salmonella to play with efferosomes

Authors (3)

Cell Host and Microbe

Published 9 February 2022

Crick labs

Maximiliano Gutierrez

Full details

Intracellular localisation of Mycobacterium tuberculosis affects efficacy of the antibiotic pyrazinamide

Authors (6)

Nature Communications

Published 21 June 2021

Crick labs/ facilities

Full details

Human stem cell-based models for studying host-pathogen interactions

Authors (2)

Cellular Microbiology

Published 1 July 2021

Crick labs

Maximiliano Gutierrez

Full details

Progress in robotics for combating infectious diseases

Authors (15)

Anzhu Gao
Robin R Murphy
Weidong Chen
Giulio Dagnino
Peer Fischer
Maximiliano Gutierrez
[...]
Jingen Xia
Ajmal Zemmar
Dandan Zhang
Chen Wang
Guang-Zhong Yang

Science Robotics

Published 31 March 2021

Crick labs

Maximiliano Gutierrez

Full details

Macrophage-specific responses to human- and animal-adapted tubercle bacilli reveal pathogen and host factors driving multinucleated cell formation

Authors (15)

Christophe Queval
Tony Fearns
Laure Botella
Alicia Smyth
Laura Schnettger
Morgane Mitermite
[...]
Matthias Trost
Dirk Werling
Francisco J Salguero
Stephen V Gordon
Maximiliano Gutierrez

PLOS Pathogens

Published 15 March 2021

Crick labs/ facilities

Full details

First person – Elliott Bernard

Authors (1)

Elliott Bernard

Journal of Cell Science

Published 1 March 2021

Crick labs

Maximiliano Gutierrez

Full details

Correlative light electron ion microscopy reveals in vivo localisation of bedaquiline in Mycobacterium tuberculosis-infected lungs

Authors (5)

PLOS Biology

Published 31 December 2020

Crick labs/ facilities

Full details

Intracellular pathogens, membrane damage and cytosolic access

Authors (1)

Pierre Santucci

Cellular Microbiology

Published 1 April 2021

Crick labs

Maximiliano Gutierrez

Full details

Rv2577 of Mycobacterium tuberculosis is a virulence factor with dual phosphatase and phosphodiesterase functions

Authors (10)

Marina Andrea Forrellad
Federico Carlos Blanco
Rubén Marrero Diaz de Villegas
Cristina Lourdes Vázquez
Agustín Yaneff
Elizabeth Andrea García
Maximiliano Gutierrez
Rosario Durán
Andrea Villarino
Fabiana Bigi

Frontiers in Microbiology

Published 22 October 2020

Crick labs

Maximiliano Gutierrez

Full details

M. tuberculosis infection of human iPSC-derived macrophages reveals complex membrane dynamics during xenophagy evasion

Authors (8)

Journal of Cell Science

Published 1 March 2021

Crick labs/ facilities

Full details

The great host-pathogen war: U.K. cellular microbiology meeting 2020

Authors (6)

Jason S King
Daniel Humphreys
Jennifer L Rohn
Meera Unnikrishnan
Maximiliano Gutierrez
Serge Mostowy

Cellular Microbiology

Published 1 November 2020

Crick labs

Maximiliano Gutierrez

Full details

LRRK2 activation controls the repair of damaged endomembranes in macrophages

Authors (8)

Susanne Herbst
Philip Campbell
John Harvey
Elliott Bernard
Venizelos Papayannopoulos
Nicholas W Wood
Huw R Morris
Maximiliano Gutierrez

The EMBO Journal

Published 15 September 2020

Crick labs/ facilities

Full details

Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers

Authors (341)

Catherine F Houlihan
Nina Vora
Thomas Byrne
Dan Lewer
Gavin Kelly
Judith Heaney
[...]
Andrew Hayward
Richard Gilson
Gavin Kelly
Fiona Roberts
Emine Hatipoglu

Research case studies

Vacancies

Cut + Paste exhibition

Coronavirus (COVID-19) research

About us

Gutierrez lab
Host-Pathogen Interactions in Tuberculosis Laboratory
: Publications

Lab content

Publications

Year published

Research topics

Crick/Pre-Crick

Publication type

Journal

ATG7 and ATG14 restrict cytosolic and phagosomal Mycobacterium tuberculosis replication in human macrophages

A terpene nucleoside from M. tuberculosis induces lysosomal lipid storage in foamy macrophages

High content quantitative imaging of Mycobacterium tuberculosis responses to acidic microenvironments within human macrophages

Lysosomal damage drives mitochondrial proteome remodelling and reprograms macrophage immunometabolism

Intracellular niche switching as host subversion strategy of bacterial pathogens

Visualizing pyrazinamide action by live single-cell imaging of phagosome acidification and Mycobacterium tuberculosis pH homeostasis

Cell wall architecture and function in microbial physiology

A sandPIT for Salmonella to play with efferosomes

Intracellular localisation of Mycobacterium tuberculosis affects efficacy of the antibiotic pyrazinamide

Human stem cell-based models for studying host-pathogen interactions

Progress in robotics for combating infectious diseases

Macrophage-specific responses to human- and animal-adapted tubercle bacilli reveal pathogen and host factors driving multinucleated cell formation

First person – Elliott Bernard

Correlative light electron ion microscopy reveals in vivo localisation of bedaquiline in Mycobacterium tuberculosis-infected lungs

Intracellular pathogens, membrane damage and cytosolic access

Rv2577 of Mycobacterium tuberculosis is a virulence factor with dual phosphatase and phosphodiesterase functions

M. tuberculosis infection of human iPSC-derived macrophages reveals complex membrane dynamics during xenophagy evasion

The great host-pathogen war: U.K. cellular microbiology meeting 2020

LRRK2 activation controls the repair of damaged endomembranes in macrophages

Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers

The Francis Crick Institute is a unique partnership between

Research case studies

Vacancies

Cut + Paste exhibition

Coronavirus (COVID-19) research

About us

Lab content

Publications

Year published

Research topics

Crick/Pre-Crick

Publication type

Journal

Publications

Share the page

The Francis Crick Institute is a unique partnership between