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Breadcrumb Maximiliano Gutierrez Gutierrez lab Host-Pathogen Interactions in Tuberculosis Laboratory : Publications Lab contentLab contentIn this section Overview Areas of interest Publications Lab news Members Vacancies Human cells infected with Mycobacterium tuberculosis (credit: Tom Lerner). White is actin cytoskeleton, red is ubiquitin, bacteria is green and nuclei are blue. Toggle to view hero caption PublicationsYear published2024 (1)2022 (1)2020 (1)2019 (1)2016 (1) Facet Year publishedResearch topicsBiochemistry & Proteomics (5)Cell Biology (5)Computational & Systems Biology (5)Human Biology & Physiology (5)Immunology (5)Infectious Disease (5)Model Organisms (5)Tumour Biology (5)Chemical Biology & High Throughput (4)Developmental Biology (4)Genetics & Genomics (4)Genome Integrity & Repair (4)Imaging (3)Metabolism (3)Gene Expression (2)Cell Cycle & Chromosomes (1)Microfabrication & Bioengineering (1)Neurosciences (1)Stem Cells (1)Structural Biology & Biophysics (1)Synthetic Biology (1) (-)Signalling & Oncogenes (5) Facet Research topicsCrick/Pre-CrickCrick publications (5) Facet Crick/Pre-CrickPublication typeJournal article (5)Primary research (4)Review (1) Facet Publication typeJournalAutophagy (1)Nature Communications (1)Science (1)Science Translational Medicine (1)The Lancet (1) Facet Journal Publications Displaying 1 - 5 of 5Last updated : 29 March 2024 02:25 Increased dosage of DYRK1A leads to congenital heart defects in a mouse model of Down syndrome Authors (20)Eva Lana-ElolaRifdat Aoidi Miriam LlorianDorota GibbinsCallan BuechsenschuetzClaudio Bussi[...] Laurent MeijerBram SnijdersMaximiliano Gutierrez Elizabeth MC FisherVictor Tybulewicz Science Translational Medicine Published 24 January 2024 Crick labs/ facilitiesVictor TybulewiczMaximiliano GutierrezProteomicsHigh Throughput ScreeningBioinformatics and BiostatisticsFull details Lysosomal damage drives mitochondrial proteome remodelling and reprograms macrophage immunometabolism Authors (17)Claudio Bussi Tiaan HeunisEnrica PellegrinoElliott Bernard Nourdine BahMariana Silva Dos Santos[...]James MacraeMaria Greco Thomas Reinheckel Matthias TrostMaximiliano Gutierrez Nature Communications Published 28 November 2022 Crick labs/ facilitiesMaximiliano GutierrezJulian DownwardMetabolomicsBioinformatics and BiostatisticsAdvanced SequencingLight MicroscopyHuman Embryonic Stem CellElectron MicroscopyAdvanced SequencingFull details Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers Authors (341) Catherine F Houlihan Nina Vora Thomas Byrne Dan LewerGavin Kelly Judith Heaney[...] Andrew Hayward Richard Gilson Gavin KellyFiona Roberts Emine Hatipoglu The Lancet Published 25 July 2020 Crick labs/ facilitiesAndreas WackKaren VousdenJernej UleJames TurnerMoritz TreeckCharles SwantonAdam SaterialeErik SahaiCaetano Reis e SousaPeter RatcliffeLucia Prieto-GodinoVenizelos PapayannopoulosAnne O’GarraPaul NurseGeorge KassiotisMaximiliano GutierrezSonia GandhiSteve GamblinPeter Cherepanov Luiz Pedro CarvalhoDominique BonnetMike BlackmanRupert BealeWorldwide Influenza CentreStructural BiologyMetabolomicsHuman Embryonic Stem CellHigh Throughput ScreeningGenetic Modification ServiceFlow CytometryFermentationExperimental HistopathologyElectron MicroscopyCell ServicesBiological Research FacilityBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details Subcellular antibiotic visualization reveals a dynamic drug reservoir in infected macrophages Authors (9)Daniel GreenwoodMariana Silva Dos Santos Song HuangMatt RussellLucy CollinsonJames Macrae Andy West Haibo JiangMaximiliano Gutierrez Science Published 28 June 2019 Crick labs/ facilitiesMaximiliano GutierrezMetabolomicsElectron MicroscopyBioinformatics and BiostatisticsFull details Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) Authors (10) Daniel J Klionsky Kotb Abdelmohsen ...Rupert Beale ...Maximiliano Gutierrez ...Charles Swanton ...Sharon Tooze Autophagy Published 2 January 2016 Crick labsSharon ToozeCharles SwantonMaximiliano GutierrezRupert BealeFull details Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Increased dosage of DYRK1A leads to congenital heart defects in a mouse model of Down syndrome Authors (20)Eva Lana-ElolaRifdat Aoidi Miriam LlorianDorota GibbinsCallan BuechsenschuetzClaudio Bussi[...] Laurent MeijerBram SnijdersMaximiliano Gutierrez Elizabeth MC FisherVictor Tybulewicz Science Translational Medicine Published 24 January 2024 Crick labs/ facilitiesVictor TybulewiczMaximiliano GutierrezProteomicsHigh Throughput ScreeningBioinformatics and BiostatisticsFull details
Lysosomal damage drives mitochondrial proteome remodelling and reprograms macrophage immunometabolism Authors (17)Claudio Bussi Tiaan HeunisEnrica PellegrinoElliott Bernard Nourdine BahMariana Silva Dos Santos[...]James MacraeMaria Greco Thomas Reinheckel Matthias TrostMaximiliano Gutierrez Nature Communications Published 28 November 2022 Crick labs/ facilitiesMaximiliano GutierrezJulian DownwardMetabolomicsBioinformatics and BiostatisticsAdvanced SequencingLight MicroscopyHuman Embryonic Stem CellElectron MicroscopyAdvanced SequencingFull details
Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers Authors (341) Catherine F Houlihan Nina Vora Thomas Byrne Dan LewerGavin Kelly Judith Heaney[...] Andrew Hayward Richard Gilson Gavin KellyFiona Roberts Emine Hatipoglu The Lancet Published 25 July 2020 Crick labs/ facilitiesAndreas WackKaren VousdenJernej UleJames TurnerMoritz TreeckCharles SwantonAdam SaterialeErik SahaiCaetano Reis e SousaPeter RatcliffeLucia Prieto-GodinoVenizelos PapayannopoulosAnne O’GarraPaul NurseGeorge KassiotisMaximiliano GutierrezSonia GandhiSteve GamblinPeter Cherepanov Luiz Pedro CarvalhoDominique BonnetMike BlackmanRupert BealeWorldwide Influenza CentreStructural BiologyMetabolomicsHuman Embryonic Stem CellHigh Throughput ScreeningGenetic Modification ServiceFlow CytometryFermentationExperimental HistopathologyElectron MicroscopyCell ServicesBiological Research FacilityBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details
Subcellular antibiotic visualization reveals a dynamic drug reservoir in infected macrophages Authors (9)Daniel GreenwoodMariana Silva Dos Santos Song HuangMatt RussellLucy CollinsonJames Macrae Andy West Haibo JiangMaximiliano Gutierrez Science Published 28 June 2019 Crick labs/ facilitiesMaximiliano GutierrezMetabolomicsElectron MicroscopyBioinformatics and BiostatisticsFull details
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) Authors (10) Daniel J Klionsky Kotb Abdelmohsen ...Rupert Beale ...Maximiliano Gutierrez ...Charles Swanton ...Sharon Tooze Autophagy Published 2 January 2016 Crick labsSharon ToozeCharles SwantonMaximiliano GutierrezRupert BealeFull details