Publications

LRRK2 in infection: Friend or foe?

Authors (2)

Susanne Herbst
Maximiliano Gutierrez

ACS Infectious Diseases

Published 14 June 2019

Crick labs

Maximiliano Gutierrez

Full details

Mycobacterium tuberculosis infection of host cells in space and time

Authors (2)

FEMS Microbiology Reviews

Published 1 July 2019

Crick labs

Maximiliano Gutierrez

Full details

Structure-based design of MptpB inhibitors that reduce multidrug-resistant Mycobacterium tuberculosis survival and infection burden in vivo

Authors (16)

Clare F Vickers
Ana PG Silva
Ajanta Chakraborty
Paulina Fernandez
Natalia Kurepina
Charis Saville
[...]
Barry N Kreiswith
David S Perlin
Eric J Thomas
Jennifer S Cavet
Lydia Tabernero

Journal of Medicinal Chemistry

Published 27 September 2018

Crick labs

Maximiliano Gutierrez

Full details

LRRK2 is a negative regulator of Mycobacterium tuberculosis phagosome maturation in macrophages

Authors (18)

Anetta Härtlova
Susanne Herbst
Julien Peltier
Angela Rodgers
Orsolya Bilkei‐Gorzo
Tony Fearns
[...]
Jennifer Martinez
Dario R Alessi
Alastair D Reith
Matthias Trost
Maximiliano Gutierrez

EMBO Journal

Published 15 June 2018

Crick labs

Maximiliano Gutierrez

Full details

ESCRTs offer repair service

Authors (2)

Science

Published 6 April 2018

Crick labs

Full details

Phthiocerol dimycocerosates promote access to the cytosol and intracellular burden of Mycobacterium tuberculosis in lymphatic endothelial cells

Authors (6)

Thomas R Lerner
Christophe Queval
Tony Fearns
Urska Repnik
Gareth Griffiths
Maximiliano Gutierrez

BMC Biology

Published 4 January 2018

Crick labs

Maximiliano Gutierrez

Full details

Mycobacterium tuberculosis modulates miR-106b-5p to control cathepsin S expression resulting in higher pathogen survival and poor T-cell activation

Authors (8)

D Pires
Elliott Bernard
JP Pombo
N Carmo
C Fialho
Maximiliano Gutierrez
P Bettencourt
E Anes

Frontiers in Immunology

Published 18 December 2017

Crick labs

Maximiliano Gutierrez

Full details

Rab GTPases in immunity and inflammation

Authors (4)

A Prashar
L Schnettger
Elliott Bernard
Maximiliano Gutierrez

Frontiers in Cellular and Infection Microbiology

Published 1 September 2017

Crick labs

Maximiliano Gutierrez

Full details

A Rab20-dependent membrane trafficking pathway controls M. tuberculosis replication by regulating phagosome spaciousness and integrity

Authors (9)

Laura Schnettger
Angela Rodgers
Urska Repnik
Rachel Lai
Gang Pei
Martijn Verdoes
Robert Wilkinson
Douglas B Young
Maximiliano Gutierrez

Cell Host & Microbe

Published 10 May 2017

Crick labs/ facilities

Full details

Reactive oxygen species localization programs inflammation to clear microbes of different size

Authors (8)

Annika Warnatsch
Theodora-Dorita Tsourouktsoglou
Nora Branzk
Qian Wang
Susanna Reincke
Susanne Herbst
Maximiliano Gutierrez
Venizelos Papayannopoulos

Immunity

Published 21 March 2017

Crick labs

Full details

Mycobacterium tuberculosis replicates within necrotic human macrophages

Authors (10)

Thomas R Lerner
Sophie Borel
Daniel Greenwood
Urska Repnik
Matt Russell
Susanne Herbst
Martin Jones
Lucy Collinson
Gareth Griffiths
Maximiliano Gutierrez

Journal of Cell Biology

Published 27 February 2017

Crick labs/ facilities

Full details

Mycobacterium bovis requires P27 (LprG) to arrest phagosome maturation and replicate within bovine macrophages

Authors (6)

Cristina Lourdes Vázquez
María Verónica Bianco
Federico Carlos Blanco
Marina Forrellad
Maximiliano Gutierrez
Fabiana Bigi

Infection and Immunity

Published 1 March 2017

Crick labs

Maximiliano Gutierrez

Full details

Quantitative spatiotemporal analysis of phagosome maturation in live cells

Authors (2)

Laura Schnettger
Maximiliano Gutierrez

Methods in Molecular Biology

Published 1 January 2017

Crick labs

Maximiliano Gutierrez

Full details

Relationship between HIV coinfection, interleukin 10 production, and Mycobacterium tuberculosis in human lymph node granulomas

Authors (9)

CR Diedrich
J O'Hern
Maximiliano Gutierrez
N Allie
P Papier
G Meintjes
AK Coussens
H Wainwright
Robert Wilkinson

Journal of Infectious Diseases

Published 1 November 2016

Crick labs

Full details

3D correlative light and electron microscopy of cultured cells using serial blockface scanning electron microscopy

Authors (15)

Matt Russell
Thomas R Lerner
Jemima J Burden
David O Nkwe
Annegret Pelchen-Matthews
Marie-Charlotte Domart
[...]
Raffaella Carzaniga
Oliver Florey
Mark Marsh
Maximiliano Gutierrez
Lucy Collinson

Journal of Cell Science

Published 2 January 2017

Crick labs/ facilities

Full details

The proneurotrophin receptor sortilin is required for Mycobacterium tuberculosis control by macrophages

Authors (10)

Cristina L Vázquez
Angela Rodgers
Susanne Herbst
Stephen Coade
Achim Gronow
Carlos A Guzman
Mark S Wilson
Makoto Kanzaki
Anders Nykjaer
Maximiliano Gutierrez

Scientific Reports

Published 8 July 2016

Crick labs/ facilities

Full details

Cell-envelope remodeling as a determinant of phenotypic antibacterial tolerance in Mycobacterium tuberculosis

Authors (10)

Gérald Larrouy-Maumus
Leonardo B Marino
Ashoka VR Madduri
TJ Ragan
Debbie M Hunt
Lucrezia Bassano
Maximiliano Gutierrez
D Branch Moody
Fernando R Pavan
Luiz Pedro Carvalho

ACS Infectious Diseases

Published 13 May 2016

Crick labs/ facilities

Full details

Lymphatic endothelial cells are a replicative niche for Mycobacterium tuberculosis

Authors (12)

Thomas R Lerner
Cristiane de Souza Carvalho-Wodarz
Urska Repnik
Matt Russell
Sophie Borel
Collin R Diedrich
[...]
Helen Wainwright
Lucy Collinson
Robert Wilkinson
Gareth Griffiths
Maximiliano Gutierrez

Journal of Clinical Investigation

Published 1 March 2016

Crick labs/ facilities

Full details

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Authors (10)

Daniel J Klionsky
Kotb Abdelmohsen
...
Rupert Beale
...
Maximiliano Gutierrez
...
Charles Swanton
...
Sharon Tooze

Autophagy

Published 2 January 2016

Crick labs

Full details

Interferon-γ-inducible Rab20 regulates endosomal morphology and EGFR degradation in macrophages

Authors (6)

Gang Pei
Laura Schnettger
Marc Bronietzki
Urska Repnik
Gareth Griffiths
Maximiliano Gutierrez

Molecular Biology of the Cell

Published 1 September 2015

Crick labs

Maximiliano Gutierrez

Full details

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LRRK2 in infection: Friend or foe?

Mycobacterium tuberculosis infection of host cells in space and time

Structure-based design of MptpB inhibitors that reduce multidrug-resistant Mycobacterium tuberculosis survival and infection burden in vivo

LRRK2 is a negative regulator of Mycobacterium tuberculosis phagosome maturation in macrophages

ESCRTs offer repair service

Phthiocerol dimycocerosates promote access to the cytosol and intracellular burden of Mycobacterium tuberculosis in lymphatic endothelial cells

Mycobacterium tuberculosis modulates miR-106b-5p to control cathepsin S expression resulting in higher pathogen survival and poor T-cell activation

Rab GTPases in immunity and inflammation

A Rab20-dependent membrane trafficking pathway controls M. tuberculosis replication by regulating phagosome spaciousness and integrity

Reactive oxygen species localization programs inflammation to clear microbes of different size

Mycobacterium tuberculosis replicates within necrotic human macrophages

Mycobacterium bovis requires P27 (LprG) to arrest phagosome maturation and replicate within bovine macrophages

Quantitative spatiotemporal analysis of phagosome maturation in live cells

Relationship between HIV coinfection, interleukin 10 production, and Mycobacterium tuberculosis in human lymph node granulomas

3D correlative light and electron microscopy of cultured cells using serial blockface scanning electron microscopy

The proneurotrophin receptor sortilin is required for Mycobacterium tuberculosis control by macrophages

Cell-envelope remodeling as a determinant of phenotypic antibacterial tolerance in Mycobacterium tuberculosis

Lymphatic endothelial cells are a replicative niche for Mycobacterium tuberculosis

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Interferon-γ-inducible Rab20 regulates endosomal morphology and EGFR degradation in macrophages

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