Publications

Regeneration of actin filament branches from the same Arp2/3 complex

Authors (7)

Foad Ghasemi
LuYan Cao
Miroslav Mladenov
Bérengère Guichard
Michael Way
Antoine Jégou
Guillaume Romet-Lemonne

Science advances

Published 26 January 2024

Crick labs

Michael Way

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Cortactin stabilizes actin branches by bridging activated Arp2/3 to its nucleated actin filament

Authors (6)

Tianyang Liu
Luyan Cao
Miroslav Mladenov
Antoine Jegou
Michael Way
Carolyn A Moores

Nature Structural and Molecular Biology

Published 24 January 2024

Crick labs

Michael Way

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Palisade structure in intact vaccinia virions

Authors (5)

mBio

Published 1 February 2024

Crick labs/ facilities

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The amount of Nck rather than N-WASP correlates with the rate of actin-based motility of Vaccinia virus

Authors (2)

Microbiology Spectrum

Published 1 December 2023

Crick labs/ facilities

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ARPC5 deficiency leads to severe early-onset systemic inflammation and mortality

Authors (11)

Elena Sindram
Andrés Caballero-Oteyza
Naoko Kogata
Shaina Chor Mei Huang
Zahra Alizadeh
Laura Gámez-Díaz
Mohammad Reza Fazlollhi
Xiao Peng
Bodo Grimbacher
Michael Way
Michele Proietti

Disease Models and Mechanisms

Published 1 July 2023

Crick labs/ facilities

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ARPC5 isoforms and their regulation by calcium-calmodulin-N-WASP drive distinct Arp2/3-dependent actin remodeling events in CD4 T cells

Authors (6)

Lopamudra Sadhu
Nikolaos Tsopoulidis
Md Hasanuzzaman
Vibor Laketa
Michael Way
Oliver T Fackler

eLife

Published 10 May 2023

Crick labs

Michael Way

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Regulation of branched versus linear Arp2/3-generated actin filaments

Authors (5)

Luyan Cao
Foad Ghasemi
Michael Way
Antoine Jégou
Guillaume Romet-Lemonne

The EMBO Journal

Published 2 May 2023

Crick labs

Michael Way

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A succession of two viral lattices drives vaccinia virus assembly

Authors (5)

PLOS Biology

Published 2 March 2023

Crick labs/ facilities

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Kinesin-1 transports morphologically distinct intracellular virions during vaccinia infection

Authors (5)

Amadeus Xu
Angika Basant
Sibylle Schleich
Timothy P Newsome
Michael Way

Journal of Cell Science

Published 1 March 2023

Crick labs/ facilities

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The relative binding position of Nck and Grb2 adaptors impacts actin-based motility of Vaccinia virus

Authors (2)

eLife

Published 7 July 2022

Crick labs/ facilities

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MICAL2 enhances branched actin network disassembly by oxidizing Arp3B-containing Arp2/3 complexes

Authors (10)

Chiara Galloni
Davide Carra
Jasmine VG Abella
Svend Kjaer
Pavithra Singaravelu
David Barry
Naoko Kogata
Christophe Guérin
Laurent Blanchoin
Michael Way

Journal of Cell Biology

Published 2 August 2021

Crick labs/ facilities

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Cryo-EM of human Arp2/3 complexes provides structural insights into actin nucleation modulation by ARPC5 isoforms

Authors (8)

Ottilie von Loeffelholz
Andrew Purkiss
Luyan Cao
Svend Kjaer
Naoko Kogata
Guillaume Romet-Lemonne
Michael Way
Carolyn A Moores

Biology Open

Published 31 July 2020

Crick labs/ facilities

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Lamellipodin tunes cell migration by stabilizing protrusions and promoting adhesion formation

Authors (11)

Georgi Dimchev
Behnam Amiri
Ashley C Humphries
Matthias Schaks
Vanessa Dimchev
Theresia EB Stradal
Jan Faix
Matthias Krause
Michael Way
Martin Falcke
Klemens Rottner

Journal of Cell Science

Published 9 April 2020

Crick labs

Michael Way

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B cells extract antigens at Arp2/3-generated actin foci interspersed with linear filaments

Authors (6)

eLife

Published 9 December 2019

Crick labs

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Deletion of apoptosis inhibitor F1L in vaccinia virus increases safety and oncolysis for cancer therapy

Authors (17)

Adrian Pelin
Johann Foloppe
Julia Petryk
Ragunath Singaravelu
Marian Hussein
Florian Gossart
[...]
Brian Laight
Michael Way
Philippe Erbs
Fabrice Le Boeuf
John C Bell

Molecular Therapy - Oncolytics

Published 27 September 2019

Crick labs

Michael Way

Full details

Insights into kinesin-1 activation from the crystal structure of KLC2 bound to JIP3

Authors (6)

Joseph JB Cockburn
Sophie J Hesketh
Peter Mulhair
Maren Thomsen
Mary J O'Connell
Michael Way

Structure

Published 6 November 2018

Crick labs

Michael Way

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Septins suppress the release of vaccinia virus from infected cells

Authors (3)

Julia Pfanzelter
Serge Mostowy
Michael Way

Journal of Cell Biology

Published 19 June 2018

Crick labs

Michael Way

Full details

Tuning of in vivo cognate B-T cell interactions by Intersectin 2 is required for effective anti-viral B cell immunity

Authors (9)

Marianne Burbage
Francesca Gasparrini
Shweta Aggarwal
Mauro Gaya
Johan Arnold
Usha Nair
Michael Way
Andreas Bruckbauer
Facundo D Batista

eLife

Published 16 January 2018

Crick labs/ facilities

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Myofibril contraction and crosslinking drive nuclear movement to the periphery of skeletal muscle

Authors (9)

William Roman
João P Martins
Filomena A Carvalho
Raphael Voituriez
Jasmine VG Abella
Nuno C Santos
Bruno Cadot
Michael Way
Edgar R Gomes

Nature Cell Biology

Published 1 October 2017

Crick labs

Michael Way

Full details

Correlative super-resolution fluorescence and electron microscopy using conventional fluorescent proteins in vacuo

Authors (8)

Chris Peddie
Marie-Charlotte Domart
Xenia Snetkov
Peter O'Toole
Banafshe Larijani
Michael Way
Susan Cox
Lucy Collinson

Journal of Structural Biology

Published 1 August 2017

Crick labs/ facilities

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: Publications

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Publications

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Journal

Regeneration of actin filament branches from the same Arp2/3 complex

Cortactin stabilizes actin branches by bridging activated Arp2/3 to its nucleated actin filament

Palisade structure in intact vaccinia virions

The amount of Nck rather than N-WASP correlates with the rate of actin-based motility of Vaccinia virus

ARPC5 deficiency leads to severe early-onset systemic inflammation and mortality

ARPC5 isoforms and their regulation by calcium-calmodulin-N-WASP drive distinct Arp2/3-dependent actin remodeling events in CD4 T cells

Regulation of branched versus linear Arp2/3-generated actin filaments

A succession of two viral lattices drives vaccinia virus assembly

Kinesin-1 transports morphologically distinct intracellular virions during vaccinia infection

The relative binding position of Nck and Grb2 adaptors impacts actin-based motility of Vaccinia virus

MICAL2 enhances branched actin network disassembly by oxidizing Arp3B-containing Arp2/3 complexes

Cryo-EM of human Arp2/3 complexes provides structural insights into actin nucleation modulation by ARPC5 isoforms

Lamellipodin tunes cell migration by stabilizing protrusions and promoting adhesion formation

B cells extract antigens at Arp2/3-generated actin foci interspersed with linear filaments

Deletion of apoptosis inhibitor F1L in vaccinia virus increases safety and oncolysis for cancer therapy

Insights into kinesin-1 activation from the crystal structure of KLC2 bound to JIP3

Septins suppress the release of vaccinia virus from infected cells

Tuning of in vivo cognate B-T cell interactions by Intersectin 2 is required for effective anti-viral B cell immunity

Myofibril contraction and crosslinking drive nuclear movement to the periphery of skeletal muscle

Correlative super-resolution fluorescence and electron microscopy using conventional fluorescent proteins in vacuo

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Hello Brain!

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Research topics

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