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Breadcrumb Michele Mishto Mishto lab Molecular Immunology Laboratory : Publications Lab contentLab contentIn this section Overview Members Publications Publications Displaying 1 - 20 of 30Last updated : 19 April 2024 03:00 Protein degradation by human 20S proteasomes elucidates the interplay between peptide hydrolysis and splicing Authors (14) Wai Tuck SohHanna Roetschke John A CormicanBei Fang Teo Nyet Cheng Chiam Monika Raabe[...] Ashwin Chari Haiyan Liu Henning Urlaub Juliane LiepeMichele Mishto Nature Communications Published 7 February 2024 Crick labsMichele MishtoFull details InvitroSPI and a large database of proteasome-generated spliced and non-spliced peptides Authors (7) Hanna P RoetschkeGuillermo RodriguezHernandez John A Cormican Xiaoping Yang Steven LynhamMichele Mishto Juliane Liepe Scientific Data Published 10 January 2023 Crick labsMichele MishtoFull details inSPIRE: An open-source tool for increased mass spectrometry identification rates using Prosit spectral prediction Authors (5) John A Cormican Yehor Horokhovskyi Wai Tuck SohMichele Mishto Juliane Liepe Molecular and Cellular Proteomics Published 1 December 2022 Crick labsMichele MishtoFull details iBench: A ground truth approach for advanced validation of mass spectrometry identification method Authors (4) John A Cormican Wai Tuck SohMichele Mishto Juliane Liepe Proteomics Published 1 January 2023 Crick labsMichele MishtoFull details Predicting the success of Fmoc-based peptide synthesis Authors (12) Ilanit Gutman Ron Gutman John Sidney Leila ChihabMichele Mishto Juliane Liepe[...] Jason Greenbaum Zhen Yan Alessandro Sette Zeynep Koşaloğlu-Yalçın Bjoern Peters ACS Omega Published 12 July 2022 Crick labsMichele MishtoFull details Database search engines and target database features impinge upon the identification of post-translationally cis-spliced peptides in HLA class I immunopeptidomes Authors (7)Michele Mishto Yehor Horokhovskyi John A Cormican Xiaoping Yang Steven Lynham Henning Urlaub Juliane Liepe Proteomics Published 1 May 2022 Crick labsMichele MishtoFull details Mechanistic diversity in MHC class I antigen recognition Authors (4)Camila Barbosa Justin Barton Adrian J ShepherdMichele Mishto Biochemical Journal Published 15 December 2021 Crick labsMichele MishtoFull details Commentary: Are there indeed spliced peptides in the immunopeptidome? Authors (1)Michele Mishto Molecular and Cellular Proteomics Published 2 October 2021 Crick labsMichele MishtoFull details Response: Commentary: An In Silico-In Vitro pipeline identifying an HLA-A*02:01+ KRAS G12V+ spliced epitope candidate for a broad tumor-immune response in cancer patients Authors (5)Michele Mishto Guillermo Rodriguez-Hernandez Jacques Neefjes Henning Urlaub Juliane Liepe Frontiers in Immunology Published 13 July 2021 Crick labsMichele MishtoFull details Identification of a class of non-conventional ER-stress-response-derived immunogenic peptides Authors (12) Alessia Melacarne Valentina Ferrari Luca TiraboschiMichele Mishto Juliane Liepe Marina Aralla[...] Michela Lizier Chiara Pozzi Offer Zeira Giuseppe Penna Maria Rescigno Cell Reports Published 6 July 2021 Crick labsMichele MishtoFull details Potential mimicry of viral and pancreatic β cell antigens through non-spliced and cis-spliced zwitter epitope candidates in type 1 diabetes Authors (4)Michele Mishto Artem Mansurkhodzhaev Teresa Rodriguez-Calvo Juliane Liepe Frontiers in Immunology Published 15 April 2021 Crick labsMichele MishtoFull details Proteasome-generated cis-spliced peptides and their potential role in CD8+ T cell tolerance Authors (4) Artem Mansurkhodzhaev Camila RR BarbosaMichele Mishto Juliane Liepe Frontiers in Immunology Published 24 February 2021 Crick labsMichele MishtoFull details What we see, what we do not see, and what we do not want to see in HLA class I immunopeptidomes Authors (1)Michele Mishto Proteomics Published 1 August 2020 Crick labsMichele MishtoFull details Large database for the analysis and prediction of spliced and non-spliced peptide generation by proteasomes Authors (8) Gerd Specht Hanna P Roetschke Artem Mansurkhodzhaev Petra Henklein Kathrin Textoris-Taube Henning UrlaubMichele Mishto Juliane Liepe Scientific Data Published 15 May 2020 Crick labsMichele MishtoFull details An in silico-in vitro pipeline identifying an HLA-A*02:01+ KRAS G12V+ spliced epitope candidate for a broad tumor-immune response in cancer patients Authors (13)Michele Mishto Artem Mansurkhodzhaev Ge Ying Aruna Bitra Robert A Cordfunke Sarah Henze[...] Henning Urlaub Jacques Neefjes Alessandro Sette Dirk M Zajonc Juliane Liepe Frontiers in Immunology Published 15 November 2019 Crick labsMichele MishtoFull details ER-aminopeptidase 1 determines the processing and presentation of an immunotherapy-relevant melanoma epitope Authors (14) Kathrin Textoris-Taube Clemens Cammann Petra Henklein Eylin Topfstedt Frédéric Ebstein Sarah Henze[...] Burkhardt Dahlmann Wolfgang Uckert Annette PaschenMichele Mishto Ulrike Seifert European Journal of Immunology Published 1 February 2020 Crick labsMichele MishtoFull details Proteolytic dynamics of human 20S thymoproteasome Authors (10) Ulrike Kuckelkorn Sabine Stübler Kathrin Textoris-Taube Christiane Kilian Agathe Niewienda Petra Henklein Katharina Janek Michael PH StumpfMichele Mishto Juliane Liepe Journal of Biological Chemistry Published 10 May 2019 Crick labsMichele MishtoFull details Untangling extracellular proteasome-osteopontin circuit dynamics in multiple sclerosis Authors (10) C Dianzani D Vecchio N Clemente A Chiocchetti FM Boneschi D Galimberti U Dianzani C ComiMichele Mishto J Liepe Cells Published 20 March 2019 Crick labsMichele MishtoFull details Mapping the MHC class I-spliced immunopeptidome of cancer cells Authors (5) Juliane Liepe John Sidney Felix KM Lorenz Alessandro SetteMichele Mishto Cancer Immunology Research Published 1 January 2019 Crick labsMichele MishtoFull details NMDA-receptor inhibition and oxidative stress during hippocampal maturation differentially alter parvalbumin expression and gamma-band activity Authors (7) Luisa A Hasam-Henderson Grace C GottiMichele Mishto Constantin Klisch Zoltan Gerevich Jörg RP Geiger Richard Kovács Scientific Reports Published 22 June 2018 Crick labsMichele MishtoFull details Pagination Current page 1 Page 2 Next page Next Last page Last Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Protein degradation by human 20S proteasomes elucidates the interplay between peptide hydrolysis and splicing Authors (14) Wai Tuck SohHanna Roetschke John A CormicanBei Fang Teo Nyet Cheng Chiam Monika Raabe[...] Ashwin Chari Haiyan Liu Henning Urlaub Juliane LiepeMichele Mishto Nature Communications Published 7 February 2024 Crick labsMichele MishtoFull details
InvitroSPI and a large database of proteasome-generated spliced and non-spliced peptides Authors (7) Hanna P RoetschkeGuillermo RodriguezHernandez John A Cormican Xiaoping Yang Steven LynhamMichele Mishto Juliane Liepe Scientific Data Published 10 January 2023 Crick labsMichele MishtoFull details
inSPIRE: An open-source tool for increased mass spectrometry identification rates using Prosit spectral prediction Authors (5) John A Cormican Yehor Horokhovskyi Wai Tuck SohMichele Mishto Juliane Liepe Molecular and Cellular Proteomics Published 1 December 2022 Crick labsMichele MishtoFull details
iBench: A ground truth approach for advanced validation of mass spectrometry identification method Authors (4) John A Cormican Wai Tuck SohMichele Mishto Juliane Liepe Proteomics Published 1 January 2023 Crick labsMichele MishtoFull details
Predicting the success of Fmoc-based peptide synthesis Authors (12) Ilanit Gutman Ron Gutman John Sidney Leila ChihabMichele Mishto Juliane Liepe[...] Jason Greenbaum Zhen Yan Alessandro Sette Zeynep Koşaloğlu-Yalçın Bjoern Peters ACS Omega Published 12 July 2022 Crick labsMichele MishtoFull details
Database search engines and target database features impinge upon the identification of post-translationally cis-spliced peptides in HLA class I immunopeptidomes Authors (7)Michele Mishto Yehor Horokhovskyi John A Cormican Xiaoping Yang Steven Lynham Henning Urlaub Juliane Liepe Proteomics Published 1 May 2022 Crick labsMichele MishtoFull details
Mechanistic diversity in MHC class I antigen recognition Authors (4)Camila Barbosa Justin Barton Adrian J ShepherdMichele Mishto Biochemical Journal Published 15 December 2021 Crick labsMichele MishtoFull details
Commentary: Are there indeed spliced peptides in the immunopeptidome? Authors (1)Michele Mishto Molecular and Cellular Proteomics Published 2 October 2021 Crick labsMichele MishtoFull details
Response: Commentary: An In Silico-In Vitro pipeline identifying an HLA-A*02:01+ KRAS G12V+ spliced epitope candidate for a broad tumor-immune response in cancer patients Authors (5)Michele Mishto Guillermo Rodriguez-Hernandez Jacques Neefjes Henning Urlaub Juliane Liepe Frontiers in Immunology Published 13 July 2021 Crick labsMichele MishtoFull details
Identification of a class of non-conventional ER-stress-response-derived immunogenic peptides Authors (12) Alessia Melacarne Valentina Ferrari Luca TiraboschiMichele Mishto Juliane Liepe Marina Aralla[...] Michela Lizier Chiara Pozzi Offer Zeira Giuseppe Penna Maria Rescigno Cell Reports Published 6 July 2021 Crick labsMichele MishtoFull details
Potential mimicry of viral and pancreatic β cell antigens through non-spliced and cis-spliced zwitter epitope candidates in type 1 diabetes Authors (4)Michele Mishto Artem Mansurkhodzhaev Teresa Rodriguez-Calvo Juliane Liepe Frontiers in Immunology Published 15 April 2021 Crick labsMichele MishtoFull details
Proteasome-generated cis-spliced peptides and their potential role in CD8+ T cell tolerance Authors (4) Artem Mansurkhodzhaev Camila RR BarbosaMichele Mishto Juliane Liepe Frontiers in Immunology Published 24 February 2021 Crick labsMichele MishtoFull details
What we see, what we do not see, and what we do not want to see in HLA class I immunopeptidomes Authors (1)Michele Mishto Proteomics Published 1 August 2020 Crick labsMichele MishtoFull details
Large database for the analysis and prediction of spliced and non-spliced peptide generation by proteasomes Authors (8) Gerd Specht Hanna P Roetschke Artem Mansurkhodzhaev Petra Henklein Kathrin Textoris-Taube Henning UrlaubMichele Mishto Juliane Liepe Scientific Data Published 15 May 2020 Crick labsMichele MishtoFull details
An in silico-in vitro pipeline identifying an HLA-A*02:01+ KRAS G12V+ spliced epitope candidate for a broad tumor-immune response in cancer patients Authors (13)Michele Mishto Artem Mansurkhodzhaev Ge Ying Aruna Bitra Robert A Cordfunke Sarah Henze[...] Henning Urlaub Jacques Neefjes Alessandro Sette Dirk M Zajonc Juliane Liepe Frontiers in Immunology Published 15 November 2019 Crick labsMichele MishtoFull details
ER-aminopeptidase 1 determines the processing and presentation of an immunotherapy-relevant melanoma epitope Authors (14) Kathrin Textoris-Taube Clemens Cammann Petra Henklein Eylin Topfstedt Frédéric Ebstein Sarah Henze[...] Burkhardt Dahlmann Wolfgang Uckert Annette PaschenMichele Mishto Ulrike Seifert European Journal of Immunology Published 1 February 2020 Crick labsMichele MishtoFull details
Proteolytic dynamics of human 20S thymoproteasome Authors (10) Ulrike Kuckelkorn Sabine Stübler Kathrin Textoris-Taube Christiane Kilian Agathe Niewienda Petra Henklein Katharina Janek Michael PH StumpfMichele Mishto Juliane Liepe Journal of Biological Chemistry Published 10 May 2019 Crick labsMichele MishtoFull details
Untangling extracellular proteasome-osteopontin circuit dynamics in multiple sclerosis Authors (10) C Dianzani D Vecchio N Clemente A Chiocchetti FM Boneschi D Galimberti U Dianzani C ComiMichele Mishto J Liepe Cells Published 20 March 2019 Crick labsMichele MishtoFull details
Mapping the MHC class I-spliced immunopeptidome of cancer cells Authors (5) Juliane Liepe John Sidney Felix KM Lorenz Alessandro SetteMichele Mishto Cancer Immunology Research Published 1 January 2019 Crick labsMichele MishtoFull details
NMDA-receptor inhibition and oxidative stress during hippocampal maturation differentially alter parvalbumin expression and gamma-band activity Authors (7) Luisa A Hasam-Henderson Grace C GottiMichele Mishto Constantin Klisch Zoltan Gerevich Jörg RP Geiger Richard Kovács Scientific Reports Published 22 June 2018 Crick labsMichele MishtoFull details
