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Breadcrumb Mike Blackman Blackman lab Malaria Biochemistry Laboratory : Publications Lab contentLab contentIn this section Overview Vacancies Areas of interest Publications Members Clusters of malaria parasites growing inside human red blood cells. 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(1)Parasitology International (1)PLOS Genetics (1)PLoS Neglected Tropical Diseases (1)RSC Advances (1)Science advances (1)The EMBO Journal (1)The Lancet (1)Traffic (1) Facet Journal Publications Displaying 1 - 20 of 93Last updated : 29 March 2023 02:34 ProteInfer, deep neural networks for protein functional inference Authors (4)Theo Sanderson Maxwell L Bileschi David Belanger Lucy J Colwell eLife Published 27 February 2023 Crick labsMike BlackmanFull details A choline-releasing glycerophosphodiesterase essential for phosphatidylcholine biosynthesis and blood stage development in the malaria parasite Authors (11)Abhinay Ramaprasad Paul-Christian BurdaEnrica CalvaniAaron SaitSusana Alejandra Palma DuranChrislaine Withers-Martinez Fiona HackettJames MacraeLucy Collinson Tim Wolf GilbergerMichael Blackman eLife Published 28 December 2022 Crick labs/ facilitiesMike BlackmanMetabolomicsElectron MicroscopyLight MicroscopyFull details Integrative genetic manipulation of Plasmodium cynomolgi reveals multidrug resistance-1 Y976F associated with increased in vitro susceptibility to mefloquine Authors (18) Kurt E Ward Peter Christensen Annie Racklyeft Satish K Dhingra Adeline CY Chua Caroline Remmert[...] Georges Snounou Laurent Rénia David A Fidock Bruce Russell Pablo Bifani Journal of Infectious Diseases Published 7 December 2022 Crick labsMike BlackmanFull details Treenome Browser: co-visualization of enormous phylogenies and millions of genomes Authors (3) Alexander M KramerTheo Sanderson Russell Corbett-Detig Bioinformatics Published 1 January 2023 Crick labsMike BlackmanFull details Taxonium, a web-based tool for exploring large phylogenetic trees Authors (1)Theo Sanderson eLife Published 15 November 2022 Crick labsMike BlackmanFull details Subtilisin-like serine protease 1 (SUB1) as an emerging antimalarial drug target: Current achievements in inhibitor discovery Authors (5) Elina LidumnieceChrislaine Withers-Martinez Fiona HackettMichael Blackman Aigars Jirgensons Journal of Medicinal Chemistry Published 13 October 2022 Crick labsMike BlackmanFull details A song for the unsung: The relevance of Plasmodium vinckei as a laboratory rodent malaria system Authors (2)Abhinay Ramaprasad Richard Culleton Parasitology International Published 1 February 2023 Crick labsMike BlackmanFull details CDC50 orthologues in Plasmodium falciparum have distinct roles in merozoite egress and trophozoite maturation Authors (4) Avnish Patel Stephanie D NofalMichael Blackman David A Baker mBio Published 1 August 2022 Crick labsMike BlackmanFull details CRISPR/Cas9 and genetic screens in malaria parasites: small genomes, big impact Authors (5) Takahiro Ishizaki Sophia Hernandez Martina S PaolettaTheo Sanderson Ellen SC Bushell Biochemical Society Transactions Published 1 June 2022 Crick labsMike BlackmanFull details Variation at Spike position 142 in SARS-CoV-2 Delta genomes is a technical artifact caused by dropout of a sequencing amplicon Authors (2)Theo Sanderson Jeffrey C Barrett Wellcome Open Research Published 10 November 2021 Crick labsMike BlackmanFull details Inhibition of protein N-myristoylation blocks Plasmodium falciparum intraerythrocytic development, egress and invasion Authors (12) Anja C SchlottEllen KnuepferJudith GreenPhilip Hobson Aaron J Borg Julia Morales-Sanfrutos[...]Catherine MaclachlanLucy CollinsonBram Snijders Edward W TateAnthony Holder PLOS Biology Published 25 October 2021 Crick labs/ facilitiesEd TateTony HolderMike BlackmanProteomicsFlow CytometryElectron MicroscopyAdvanced SequencingFull details Synchrony between daily rhythms of malaria parasites and hosts is driven by an essential amino acid Authors (9) Kimberley F Prior Benita Middleton Alíz TY Owolabi Mary L Westwood Jacob Holland Aidan J O'DonnellMichael Blackman Debra J Skene Sarah E Reece Wellcome Open Research Published 20 October 2021 Crick labsMike BlackmanFull details Mixology: A tool for calculating required masses and volumes for laboratory solutions Authors (1)Theo Sanderson Wellcome Open Research Published 26 May 2021 Crick labsMike BlackmanFull details Peptidic boronic acids are potent cell-permeable inhibitors of the malaria parasite egress serine protease SUB1 Authors (9) Elina LidumnieceChrislaine Withers-Martinez Fiona Hackett Christine R CollinsAbi PerrinKostas Kousis Claudine BissonMichael Blackman Aigars Jirgensons Proceedings of the National Academy of Sciences of USA Published 18 May 2021 Crick labsMike BlackmanFull details Autocatalytic activation of a malarial egress protease is druggable and requires a protein cofactor Authors (11)Michele TanKostas KousisChrislaine Withers-Martinez Steven A Howell James A Thomas Fiona HackettEllen Knuepfer Min Shen Matthew D HallBram SnijdersMichael Blackman The EMBO Journal Published 1 June 2021 Crick labs/ facilitiesMike BlackmanProteomicsFull details Ca2+ signals critical for egress and gametogenesis in malaria parasites depend on a multipass membrane protein that interacts with PKG Authors (19) Aurélia C BalestraKostas Kousis Natacha Klages Steven A Howell Helen R Flynn Marcus Bantscheff[...] Sonja Ghidelli-DisseBram Snijders David A BakerMichael Blackman Mathieu Brochet Science advances Published 24 March 2021 Crick labs/ facilitiesMike BlackmanProteomicsFull details Malaria parasite schizont egress antigen-1 plays an essential role in nuclear segregation during schizogony Authors (10)Abi Perrin Claudine BissonPeter FaullMatt Renshaw Rebecca A Lees Roland A Fleck Helen R SaibilBram Snijders David A BakerMichael Blackman mBio Published 1 March 2021 Crick labs/ facilitiesMike BlackmanProteomicsLight MicroscopyFull details Malaria parasite egress at a glance Authors (2)Michele TanMichael Blackman Journal of Cell Science Published 8 March 2021 Crick labsMike BlackmanFull details Plasmodium falciparum guanylyl cyclase-alpha and the activity of its appended P4-ATPase domain are essential for cGMP synthesis and blood-stage egress Authors (5) Stephanie D Nofal Avnish PatelMichael Blackman Christian Flueck David A Baker mBio Published 1 January 2021 Crick labsMike BlackmanFull details The malaria parasite sheddase SUB2 governs host red blood cell membrane sealing at invasion Authors (7) Christine R Collins Fiona Hackett Steven A HowellBram SnijdersMatt RussellLucy CollinsonMichael Blackman eLife Published 8 December 2020 Crick labs/ facilitiesMike BlackmanProteomicsElectron MicroscopyFull details Pagination Current page 1 Page 2 Page 3 Page 4 Page 5 Next page Next Last page Last Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
ProteInfer, deep neural networks for protein functional inference Authors (4)Theo Sanderson Maxwell L Bileschi David Belanger Lucy J Colwell eLife Published 27 February 2023 Crick labsMike BlackmanFull details
A choline-releasing glycerophosphodiesterase essential for phosphatidylcholine biosynthesis and blood stage development in the malaria parasite Authors (11)Abhinay Ramaprasad Paul-Christian BurdaEnrica CalvaniAaron SaitSusana Alejandra Palma DuranChrislaine Withers-Martinez Fiona HackettJames MacraeLucy Collinson Tim Wolf GilbergerMichael Blackman eLife Published 28 December 2022 Crick labs/ facilitiesMike BlackmanMetabolomicsElectron MicroscopyLight MicroscopyFull details
Integrative genetic manipulation of Plasmodium cynomolgi reveals multidrug resistance-1 Y976F associated with increased in vitro susceptibility to mefloquine Authors (18) Kurt E Ward Peter Christensen Annie Racklyeft Satish K Dhingra Adeline CY Chua Caroline Remmert[...] Georges Snounou Laurent Rénia David A Fidock Bruce Russell Pablo Bifani Journal of Infectious Diseases Published 7 December 2022 Crick labsMike BlackmanFull details
Treenome Browser: co-visualization of enormous phylogenies and millions of genomes Authors (3) Alexander M KramerTheo Sanderson Russell Corbett-Detig Bioinformatics Published 1 January 2023 Crick labsMike BlackmanFull details
Taxonium, a web-based tool for exploring large phylogenetic trees Authors (1)Theo Sanderson eLife Published 15 November 2022 Crick labsMike BlackmanFull details
Subtilisin-like serine protease 1 (SUB1) as an emerging antimalarial drug target: Current achievements in inhibitor discovery Authors (5) Elina LidumnieceChrislaine Withers-Martinez Fiona HackettMichael Blackman Aigars Jirgensons Journal of Medicinal Chemistry Published 13 October 2022 Crick labsMike BlackmanFull details
A song for the unsung: The relevance of Plasmodium vinckei as a laboratory rodent malaria system Authors (2)Abhinay Ramaprasad Richard Culleton Parasitology International Published 1 February 2023 Crick labsMike BlackmanFull details
CDC50 orthologues in Plasmodium falciparum have distinct roles in merozoite egress and trophozoite maturation Authors (4) Avnish Patel Stephanie D NofalMichael Blackman David A Baker mBio Published 1 August 2022 Crick labsMike BlackmanFull details
CRISPR/Cas9 and genetic screens in malaria parasites: small genomes, big impact Authors (5) Takahiro Ishizaki Sophia Hernandez Martina S PaolettaTheo Sanderson Ellen SC Bushell Biochemical Society Transactions Published 1 June 2022 Crick labsMike BlackmanFull details
Variation at Spike position 142 in SARS-CoV-2 Delta genomes is a technical artifact caused by dropout of a sequencing amplicon Authors (2)Theo Sanderson Jeffrey C Barrett Wellcome Open Research Published 10 November 2021 Crick labsMike BlackmanFull details
Inhibition of protein N-myristoylation blocks Plasmodium falciparum intraerythrocytic development, egress and invasion Authors (12) Anja C SchlottEllen KnuepferJudith GreenPhilip Hobson Aaron J Borg Julia Morales-Sanfrutos[...]Catherine MaclachlanLucy CollinsonBram Snijders Edward W TateAnthony Holder PLOS Biology Published 25 October 2021 Crick labs/ facilitiesEd TateTony HolderMike BlackmanProteomicsFlow CytometryElectron MicroscopyAdvanced SequencingFull details
Synchrony between daily rhythms of malaria parasites and hosts is driven by an essential amino acid Authors (9) Kimberley F Prior Benita Middleton Alíz TY Owolabi Mary L Westwood Jacob Holland Aidan J O'DonnellMichael Blackman Debra J Skene Sarah E Reece Wellcome Open Research Published 20 October 2021 Crick labsMike BlackmanFull details
Mixology: A tool for calculating required masses and volumes for laboratory solutions Authors (1)Theo Sanderson Wellcome Open Research Published 26 May 2021 Crick labsMike BlackmanFull details
Peptidic boronic acids are potent cell-permeable inhibitors of the malaria parasite egress serine protease SUB1 Authors (9) Elina LidumnieceChrislaine Withers-Martinez Fiona Hackett Christine R CollinsAbi PerrinKostas Kousis Claudine BissonMichael Blackman Aigars Jirgensons Proceedings of the National Academy of Sciences of USA Published 18 May 2021 Crick labsMike BlackmanFull details
Autocatalytic activation of a malarial egress protease is druggable and requires a protein cofactor Authors (11)Michele TanKostas KousisChrislaine Withers-Martinez Steven A Howell James A Thomas Fiona HackettEllen Knuepfer Min Shen Matthew D HallBram SnijdersMichael Blackman The EMBO Journal Published 1 June 2021 Crick labs/ facilitiesMike BlackmanProteomicsFull details
Ca2+ signals critical for egress and gametogenesis in malaria parasites depend on a multipass membrane protein that interacts with PKG Authors (19) Aurélia C BalestraKostas Kousis Natacha Klages Steven A Howell Helen R Flynn Marcus Bantscheff[...] Sonja Ghidelli-DisseBram Snijders David A BakerMichael Blackman Mathieu Brochet Science advances Published 24 March 2021 Crick labs/ facilitiesMike BlackmanProteomicsFull details
Malaria parasite schizont egress antigen-1 plays an essential role in nuclear segregation during schizogony Authors (10)Abi Perrin Claudine BissonPeter FaullMatt Renshaw Rebecca A Lees Roland A Fleck Helen R SaibilBram Snijders David A BakerMichael Blackman mBio Published 1 March 2021 Crick labs/ facilitiesMike BlackmanProteomicsLight MicroscopyFull details
Malaria parasite egress at a glance Authors (2)Michele TanMichael Blackman Journal of Cell Science Published 8 March 2021 Crick labsMike BlackmanFull details
Plasmodium falciparum guanylyl cyclase-alpha and the activity of its appended P4-ATPase domain are essential for cGMP synthesis and blood-stage egress Authors (5) Stephanie D Nofal Avnish PatelMichael Blackman Christian Flueck David A Baker mBio Published 1 January 2021 Crick labsMike BlackmanFull details
The malaria parasite sheddase SUB2 governs host red blood cell membrane sealing at invasion Authors (7) Christine R Collins Fiona Hackett Steven A HowellBram SnijdersMatt RussellLucy CollinsonMichael Blackman eLife Published 8 December 2020 Crick labs/ facilitiesMike BlackmanProteomicsElectron MicroscopyFull details