Publications

A patatin-like phospholipase is important for mitochondrial function in malaria parasites

Authors (13)

Emma Pietsch
Abhinay Ramaprasad
Sabrina Bielfeld
Yvonne Wohlfarter
Bohumil Maco
Korbinian Niedermüller
[...]
Markus A Keller
Dominique Soldati-Favre
Michael Blackman
Tim-Wolf Gilberger
Paul-Christian Burda

mBio

Published 26 October 2023

Crick labs

Mike Blackman

Full details

A molnupiravir-associated mutational signature in global SARS-CoV-2 genomes

Authors (7)

Theo Sanderson
Ryan Hisner
I’ah Donovan-Banfield
Hassan Hartman
Alessandra Løchen
Thomas P Peacock
Christopher Ruis

Nature

Published 16 November 2023

Crick labs

Mike Blackman

Full details

Macrocyclic peptidomimetic plasmepsin X inhibitors with potent in vitro and in vivo antimalarial activity

Authors (16)

Vadims Kovada
Chrislaine Withers-Martinez
Raitis Bobrovs
Hele̅na Ce̅rule
Edgars Liepins
Solveiga Grinberga
[...]
Dace Rasina
Edgars Suna
Kristaps Jaudzems
Michael Blackman
Aigars Jirgensons

Journal of Medicinal Chemistry

Published 10 August 2023

Crick labs

Mike Blackman

Full details

Global analysis of putative phospholipases in Plasmodium falciparum reveals an essential role of the phosphoinositide-specific phospholipase C in parasite maturation

Authors (13)

Paul-Christian Burda
Abhinay Ramaprasad
Sabrina Bielfeld
Emma Pietsch
Anna Woitalla
Christoph Söhnchen
[...]
Aaron Sait
Lucy Collinson
Dominik Schwudke
Michael Blackman
Tim-Wolf Gilberger

mBio

Published 31 August 2023

Crick labs/ facilities

Full details

The role of Plasmodium V-ATPase in vacuolar physiology and antimalarial drug uptake

Authors (8)

Arne Alder
Cecilia P Sanchez
Matt Russell
Lucy Collinson
Michael Lanzer
Michael Blackman
Tim-Wolf Gilberger
Joachim M Matz

Proceedings of the National Academy of Sciences of USA

Published 25 July 2023

Crick labs/ facilities

Full details

A malaria parasite phospholipase facilitates efficient asexual blood stage egress

Authors (11)

Abhinay Ramaprasad
Paul-Christian Burda
Kostas Kousis
James A Thomas
Emma Pietsch
Enrica Calvani
Steven A Howell
James Macrae
Bram Snijders
Tim-Wolf Gilberger
Michael Blackman

PLOS Pathogens

Published 23 June 2023

Crick labs/ facilities

Full details

Independent SARS-CoV-2 staff testing protected academic and health-care institutions in northwest London

Authors (54)

Chris Bailey
Theo Sanderson
Hermaleigh Townsley
Jacki Goldman
James RM Black
George Young
[...]
Jerome Nicod
Sonia Gandhi
David LV Bauer
Emma C Wall
Charles Swanton

The Lancet

Published 1 July 2023

Crick labs/ facilities

Full details

ProteInfer, deep neural networks for protein functional inference

Authors (4)

Theo Sanderson
Maxwell L Bileschi
David Belanger
Lucy J Colwell

eLife

Published 27 February 2023

Crick labs

Mike Blackman

Full details

A choline-releasing glycerophosphodiesterase essential for phosphatidylcholine biosynthesis and blood stage development in the malaria parasite

Authors (11)

eLife

Published 28 December 2022

Crick labs/ facilities

Full details

Integrative genetic manipulation of Plasmodium cynomolgi reveals multidrug resistance-1 Y976F associated with increased in vitro susceptibility to mefloquine

Authors (18)

Kurt E Ward
Peter Christensen
Annie Racklyeft
Satish K Dhingra
Adeline CY Chua
Caroline Remmert
[...]
Georges Snounou
Laurent Rénia
David A Fidock
Bruce Russell
Pablo Bifani

Journal of Infectious Diseases

Published 15 May 2023

Crick labs

Mike Blackman

Full details

Treenome Browser: co-visualization of enormous phylogenies and millions of genomes

Authors (3)

Alexander M Kramer
Theo Sanderson
Russell Corbett-Detig

Bioinformatics

Published 1 January 2023

Crick labs

Mike Blackman

Full details

Taxonium, a web-based tool for exploring large phylogenetic trees

Authors (1)

Theo Sanderson

eLife

Published 15 November 2022

Crick labs

Mike Blackman

Full details

Subtilisin-like serine protease 1 (SUB1) as an emerging antimalarial drug target: Current achievements in inhibitor discovery

Authors (5)

Elina Lidumniece
Chrislaine Withers-Martinez
Fiona Hackett
Michael Blackman
Aigars Jirgensons

Journal of Medicinal Chemistry

Published 13 October 2022

Crick labs

Mike Blackman

Full details

A song for the unsung: The relevance of Plasmodium vinckei as a laboratory rodent malaria system

Authors (2)

Abhinay Ramaprasad
Richard Culleton

Parasitology International

Published 1 February 2023

Crick labs

Mike Blackman

Full details

CDC50 orthologues in Plasmodium falciparum have distinct roles in merozoite egress and trophozoite maturation

Authors (4)

Avnish Patel
Stephanie Nofal
Michael Blackman
David A Baker

mBio

Published 1 August 2022

Crick labs

Mike Blackman

Full details

CRISPR/Cas9 and genetic screens in malaria parasites: small genomes, big impact

Authors (5)

Takahiro Ishizaki
Sophia Hernandez
Martina S Paoletta
Theo Sanderson
Ellen SC Bushell

Biochemical Society Transactions

Published 1 June 2022

Crick labs

Mike Blackman

Full details

Variation at Spike position 142 in SARS-CoV-2 Delta genomes is a technical artifact caused by dropout of a sequencing amplicon

Authors (2)

Theo Sanderson
Jeffrey C Barrett

Wellcome Open Research

Published 10 November 2021

Crick labs

Mike Blackman

Full details

Inhibition of protein N-myristoylation blocks Plasmodium falciparum intraerythrocytic development, egress and invasion

Authors (12)

Anja C Schlott
Ellen Knuepfer
Judith Green
Philip Hobson
Aaron J Borg
Julia Morales-Sanfrutos
[...]
Catherine Maclachlan
Lucy Collinson
Bram Snijders
Edward W Tate
Anthony Holder

PLOS Biology

Published 25 October 2021

Crick labs/ facilities

Full details

Synchrony between daily rhythms of malaria parasites and hosts is driven by an essential amino acid

Authors (9)

Kimberley F Prior
Benita Middleton
Alíz TY Owolabi
Mary L Westwood
Jacob Holland
Aidan J O'Donnell
Michael Blackman
Debra J Skene
Sarah E Reece

Wellcome Open Research

Published 20 October 2021

Crick labs

Mike Blackman

Full details

Mixology: A tool for calculating required masses and volumes for laboratory solutions

Authors (1)

Theo Sanderson

Wellcome Open Research

Published 26 May 2021

Crick labs

Mike Blackman

Full details

Research case studies

Doctoral clinical fellows

Cut + Paste exhibition

News and reports

About us

Blackman lab
Malaria Biochemistry Laboratory
: Publications

Lab content

Publications

Year published

Research topics

Publication type

Journal

A patatin-like phospholipase is important for mitochondrial function in malaria parasites

A molnupiravir-associated mutational signature in global SARS-CoV-2 genomes

Macrocyclic peptidomimetic plasmepsin X inhibitors with potent in vitro and in vivo antimalarial activity

Global analysis of putative phospholipases in Plasmodium falciparum reveals an essential role of the phosphoinositide-specific phospholipase C in parasite maturation

The role of Plasmodium V-ATPase in vacuolar physiology and antimalarial drug uptake

A malaria parasite phospholipase facilitates efficient asexual blood stage egress

Independent SARS-CoV-2 staff testing protected academic and health-care institutions in northwest London

ProteInfer, deep neural networks for protein functional inference

A choline-releasing glycerophosphodiesterase essential for phosphatidylcholine biosynthesis and blood stage development in the malaria parasite

Integrative genetic manipulation of Plasmodium cynomolgi reveals multidrug resistance-1 Y976F associated with increased in vitro susceptibility to mefloquine

Treenome Browser: co-visualization of enormous phylogenies and millions of genomes

Taxonium, a web-based tool for exploring large phylogenetic trees

Subtilisin-like serine protease 1 (SUB1) as an emerging antimalarial drug target: Current achievements in inhibitor discovery

A song for the unsung: The relevance of Plasmodium vinckei as a laboratory rodent malaria system

CDC50 orthologues in Plasmodium falciparum have distinct roles in merozoite egress and trophozoite maturation

CRISPR/Cas9 and genetic screens in malaria parasites: small genomes, big impact

Variation at Spike position 142 in SARS-CoV-2 Delta genomes is a technical artifact caused by dropout of a sequencing amplicon

Inhibition of protein N-myristoylation blocks Plasmodium falciparum intraerythrocytic development, egress and invasion

Synchrony between daily rhythms of malaria parasites and hosts is driven by an essential amino acid

Mixology: A tool for calculating required masses and volumes for laboratory solutions

The Francis Crick Institute is a unique partnership between

Research case studies

Doctoral clinical fellows

Cut + Paste exhibition

News and reports

About us

Lab content

Publications

Year published

Research topics

Publication type

Journal

Publications

Share the page

The Francis Crick Institute is a unique partnership between