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Breadcrumb Mike Blackman Blackman lab Malaria Biochemistry Laboratory : Publications Lab contentLab contentIn this section Overview Vacancies Areas of interest Publications Members Clusters of malaria parasites growing inside human red blood cells. Toggle to view hero caption PublicationsYear published2023 (3)2022 (1)2021 (2)2020 (3)2019 (1)2018 (1) Facet Year publishedResearch topicsBiochemistry & Proteomics (11)Cell Biology (11)Immunology (11)Infectious Disease (11)Model Organisms (11)Structural Biology & Biophysics (11)Computational & Systems Biology (6)Chemical Biology & High Throughput (5)Human Biology & Physiology (4)Tumour Biology (4)Cell Cycle & Chromosomes (3)Developmental Biology (3)Metabolism (3)Signalling & Oncogenes (3)Stem Cells (3)Gene Expression (2)Genetics & Genomics (2)Genome Integrity & Repair (2)Microfabrication & Bioengineering (2)Neurosciences (2)Synthetic Biology (2) (-)Imaging (11) Facet Research topicsPublication typeJournal article (11)Primary research (10)Letter (1) Facet Publication typeJournalmBio (3)eLife (2)Proceedings of the National Academy of Sciences of USA (2)The Lancet (2)PLOS Biology (1)PLOS Pathogens (1) Facet Journal Publications Displaying 1 - 11 of 11Last updated : 23 April 2024 02:46 Global analysis of putative phospholipases in Plasmodium falciparum reveals an essential role of the phosphoinositide-specific phospholipase C in parasite maturation Authors (13) Paul-Christian BurdaAbhinay Ramaprasad Sabrina Bielfeld Emma Pietsch Anna Woitalla Christoph Söhnchen[...]Aaron SaitLucy Collinson Dominik SchwudkeMichael Blackman Tim-Wolf Gilberger mBio Published 31 August 2023 Crick labs/ facilitiesMike BlackmanElectron MicroscopyFull details The role of Plasmodium V-ATPase in vacuolar physiology and antimalarial drug uptake Authors (8) Arne Alder Cecilia P SanchezMatt RussellLucy Collinson Michael LanzerMichael Blackman Tim-Wolf Gilberger Joachim M Matz Proceedings of the National Academy of Sciences of USA Published 25 July 2023 Crick labs/ facilitiesMike BlackmanElectron MicroscopyFull details Independent SARS-CoV-2 staff testing protected academic and health-care institutions in northwest London Authors (54) Chris BaileyTheo Sanderson Hermaleigh Townsley Jacki Goldman James RM BlackGeorge Young[...]Jerome NicodSonia GandhiDavid LV Bauer Emma C WallCharles Swanton The Lancet Published 1 July 2023 Crick labs/ facilitiesSamra TurajlicCharles SwantonSam RodriquesSonia GandhiSteve GamblinMike BlackmanRupert BealeDavid LV BauerWorldwide Influenza CentreStructural BiologyMetabolomicsHigh Throughput ScreeningFlow CytometryBioinformatics and BiostatisticsAdvanced SequencingScientific computingBiological Research FacilityFull details A choline-releasing glycerophosphodiesterase essential for phosphatidylcholine biosynthesis and blood stage development in the malaria parasite Authors (11)Abhinay Ramaprasad Paul-Christian BurdaEnrica CalvaniAaron SaitSusana Palma-DuranChrislaine Withers-Martinez Fiona HackettJames MacraeLucy Collinson Tim Wolf GilbergerMichael Blackman eLife Published 28 December 2022 Crick labs/ facilitiesMike BlackmanMetabolomicsElectron MicroscopyLight MicroscopyFull details Inhibition of protein N-myristoylation blocks Plasmodium falciparum intraerythrocytic development, egress and invasion Authors (12) Anja C SchlottEllen KnuepferJudith GreenPhilip Hobson Aaron J Borg Julia Morales-Sanfrutos[...]Catherine MaclachlanLucy CollinsonBram Snijders Edward W TateAnthony Holder PLOS Biology Published 25 October 2021 Crick labs/ facilitiesEd TateTony HolderMike BlackmanProteomicsFlow CytometryElectron MicroscopyAdvanced SequencingFull details Malaria parasite schizont egress antigen-1 plays an essential role in nuclear segregation during schizogony Authors (10)Abigail Perrin Claudine BissonPeter FaullMatt Renshaw Rebecca A Lees Roland A Fleck Helen R SaibilBram Snijders David A BakerMichael Blackman mBio Published 1 March 2021 Crick labs/ facilitiesMike BlackmanProteomicsLight MicroscopyFull details The malaria parasite sheddase SUB2 governs host red blood cell membrane sealing at invasion Authors (7) Christine R Collins Fiona Hackett Steven A HowellBram SnijdersMatt RussellLucy CollinsonMichael Blackman eLife Published 8 December 2020 Crick labs/ facilitiesMike BlackmanProteomicsElectron MicroscopyFull details Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers Authors (341) Catherine F Houlihan Nina Vora Thomas Byrne Dan LewerGavin Kelly Judith Heaney[...] Andrew Hayward Richard Gilson Gavin KellyFiona Roberts Emine Hatipoglu The Lancet Published 25 July 2020 Crick labs/ facilitiesAndreas WackKaren VousdenJernej UleJames TurnerMoritz TreeckCharles SwantonAdam SaterialeErik SahaiCaetano Reis e SousaPeter RatcliffeLucia Prieto-GodinoVenizelos PapayannopoulosAnne O’GarraPaul NurseGeorge KassiotisMaximiliano GutierrezSonia GandhiSteve GamblinPeter Cherepanov Luiz Pedro CarvalhoDominique BonnetMike BlackmanRupert BealeWorldwide Influenza CentreStructural BiologyMetabolomicsHuman Embryonic Stem CellHigh Throughput ScreeningGenetic Modification ServiceFlow CytometryFermentationExperimental HistopathologyElectron MicroscopyCell ServicesBiological Research FacilityBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details A lipocalin mediates unidirectional heme biomineralization in malaria parasites Authors (11) Joachim M Matz Benjamin Drepper Thorsten B Blum Eric van Genderen Alana Burrell Peer Martin Thomas StachLucy Collinson Jan Pieter Abrahams Kai MatuschewskiMichael Blackman Proceedings of the National Academy of Sciences of USA Published 14 July 2020 Crick labs/ facilitiesMike BlackmanElectron MicroscopyLight MicroscopyFull details The Plasmodium falciparum rhoptry bulb protein RAMA plays an essential role in rhoptry neck morphogenesis and host red blood cell invasion Authors (7) Emma S SherlingAbigail PerrinEllen KnuepferMatt RussellLucy Collinson Louis H MillerMichael Blackman PLOS Pathogens Published 6 September 2019 Crick labs/ facilitiesTony HolderMike BlackmanElectron MicroscopyFull details The actinomyosin motor drives malaria parasite red blood cell invasion but not egress Authors (6)Abigail Perrin Christine R CollinsMatt RussellLucy Collinson David A BakerMichael Blackman mBio Published 3 July 2018 Crick labs/ facilitiesMike BlackmanElectron MicroscopyFull details Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Global analysis of putative phospholipases in Plasmodium falciparum reveals an essential role of the phosphoinositide-specific phospholipase C in parasite maturation Authors (13) Paul-Christian BurdaAbhinay Ramaprasad Sabrina Bielfeld Emma Pietsch Anna Woitalla Christoph Söhnchen[...]Aaron SaitLucy Collinson Dominik SchwudkeMichael Blackman Tim-Wolf Gilberger mBio Published 31 August 2023 Crick labs/ facilitiesMike BlackmanElectron MicroscopyFull details
The role of Plasmodium V-ATPase in vacuolar physiology and antimalarial drug uptake Authors (8) Arne Alder Cecilia P SanchezMatt RussellLucy Collinson Michael LanzerMichael Blackman Tim-Wolf Gilberger Joachim M Matz Proceedings of the National Academy of Sciences of USA Published 25 July 2023 Crick labs/ facilitiesMike BlackmanElectron MicroscopyFull details
Independent SARS-CoV-2 staff testing protected academic and health-care institutions in northwest London Authors (54) Chris BaileyTheo Sanderson Hermaleigh Townsley Jacki Goldman James RM BlackGeorge Young[...]Jerome NicodSonia GandhiDavid LV Bauer Emma C WallCharles Swanton The Lancet Published 1 July 2023 Crick labs/ facilitiesSamra TurajlicCharles SwantonSam RodriquesSonia GandhiSteve GamblinMike BlackmanRupert BealeDavid LV BauerWorldwide Influenza CentreStructural BiologyMetabolomicsHigh Throughput ScreeningFlow CytometryBioinformatics and BiostatisticsAdvanced SequencingScientific computingBiological Research FacilityFull details
A choline-releasing glycerophosphodiesterase essential for phosphatidylcholine biosynthesis and blood stage development in the malaria parasite Authors (11)Abhinay Ramaprasad Paul-Christian BurdaEnrica CalvaniAaron SaitSusana Palma-DuranChrislaine Withers-Martinez Fiona HackettJames MacraeLucy Collinson Tim Wolf GilbergerMichael Blackman eLife Published 28 December 2022 Crick labs/ facilitiesMike BlackmanMetabolomicsElectron MicroscopyLight MicroscopyFull details
Inhibition of protein N-myristoylation blocks Plasmodium falciparum intraerythrocytic development, egress and invasion Authors (12) Anja C SchlottEllen KnuepferJudith GreenPhilip Hobson Aaron J Borg Julia Morales-Sanfrutos[...]Catherine MaclachlanLucy CollinsonBram Snijders Edward W TateAnthony Holder PLOS Biology Published 25 October 2021 Crick labs/ facilitiesEd TateTony HolderMike BlackmanProteomicsFlow CytometryElectron MicroscopyAdvanced SequencingFull details
Malaria parasite schizont egress antigen-1 plays an essential role in nuclear segregation during schizogony Authors (10)Abigail Perrin Claudine BissonPeter FaullMatt Renshaw Rebecca A Lees Roland A Fleck Helen R SaibilBram Snijders David A BakerMichael Blackman mBio Published 1 March 2021 Crick labs/ facilitiesMike BlackmanProteomicsLight MicroscopyFull details
The malaria parasite sheddase SUB2 governs host red blood cell membrane sealing at invasion Authors (7) Christine R Collins Fiona Hackett Steven A HowellBram SnijdersMatt RussellLucy CollinsonMichael Blackman eLife Published 8 December 2020 Crick labs/ facilitiesMike BlackmanProteomicsElectron MicroscopyFull details
Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers Authors (341) Catherine F Houlihan Nina Vora Thomas Byrne Dan LewerGavin Kelly Judith Heaney[...] Andrew Hayward Richard Gilson Gavin KellyFiona Roberts Emine Hatipoglu The Lancet Published 25 July 2020 Crick labs/ facilitiesAndreas WackKaren VousdenJernej UleJames TurnerMoritz TreeckCharles SwantonAdam SaterialeErik SahaiCaetano Reis e SousaPeter RatcliffeLucia Prieto-GodinoVenizelos PapayannopoulosAnne O’GarraPaul NurseGeorge KassiotisMaximiliano GutierrezSonia GandhiSteve GamblinPeter Cherepanov Luiz Pedro CarvalhoDominique BonnetMike BlackmanRupert BealeWorldwide Influenza CentreStructural BiologyMetabolomicsHuman Embryonic Stem CellHigh Throughput ScreeningGenetic Modification ServiceFlow CytometryFermentationExperimental HistopathologyElectron MicroscopyCell ServicesBiological Research FacilityBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details
A lipocalin mediates unidirectional heme biomineralization in malaria parasites Authors (11) Joachim M Matz Benjamin Drepper Thorsten B Blum Eric van Genderen Alana Burrell Peer Martin Thomas StachLucy Collinson Jan Pieter Abrahams Kai MatuschewskiMichael Blackman Proceedings of the National Academy of Sciences of USA Published 14 July 2020 Crick labs/ facilitiesMike BlackmanElectron MicroscopyLight MicroscopyFull details
The Plasmodium falciparum rhoptry bulb protein RAMA plays an essential role in rhoptry neck morphogenesis and host red blood cell invasion Authors (7) Emma S SherlingAbigail PerrinEllen KnuepferMatt RussellLucy Collinson Louis H MillerMichael Blackman PLOS Pathogens Published 6 September 2019 Crick labs/ facilitiesTony HolderMike BlackmanElectron MicroscopyFull details
The actinomyosin motor drives malaria parasite red blood cell invasion but not egress Authors (6)Abigail Perrin Christine R CollinsMatt RussellLucy Collinson David A BakerMichael Blackman mBio Published 3 July 2018 Crick labs/ facilitiesMike BlackmanElectron MicroscopyFull details