Blackman lab
Malaria Biochemistry Laboratory
: Publications

Publications

Displaying 41 - 60 of 102

Last updated : 23 April 2024 02:22

Characterization of P. falciparum dipeptidyl aminopeptidase 3 specificity identifies differences in amino acid preferences between peptide-based substrates and covalent inhibitors

Authors (16)

Laura E de Vries
Mateo I Sanchez
Katarzyna Groborz
Laurie Kuppens
Marcin Poreba
Christine Lehmann
[...]
Martin Horn
Michael Mares
Matthew Bogyo
Marcin Drag
Edgar Deu Sandoval

FEBS Journal

Published 1 October 2019

Crick labs

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Cyclic AMP signalling controls key components of malaria parasite host cell invasion machinery

Authors (14)

Avnish Patel
Abigail Perrin
Helen R Flynn
Claudine Bisson
Chrislaine Withers-Martinez
Moritz Treeck
[...]
Andres Ramos
Tim W Gilberger
Bram Snijders
Michael Blackman
David A Baker

PLOS Biology

Published 10 May 2019

Crick labs/ facilities

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The Plasmodium berghei serine protease PbSUB1 plays an important role in male gamete egress

Authors (7)

Tomasino Pace
Felicia Grasso
Grazia Camarda
Catherine Suarez
Michael Blackman
Marta Ponzi
Anna Olivieri

Cellular Microbiology

Published 1 July 2019

Crick labs

Mike Blackman

Full details

Phosphodiesterase beta is the master regulator of cAMP signalling during malaria parasite invasion

Authors (10)

Christian Flueck
Laura G Drought
Andrew Jones
Avnish Patel
Abigail Perrin
Eloise M Walker
Stephanie Nofal
Bram Snijders
Michael Blackman
David A Baker

PLOS Biology

Published 22 February 2019

Crick labs/ facilities

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Peptidomimetic plasmepsin inhibitors with potent anti-malarial activity and selectivity against cathepsin D

Authors (11)

Rimants Zogota
Linda Kinena
Chrislaine Withers-Martinez
Michael Blackman
Raitis Bobrovs
Teodors Pantelejevs
Iveta Kanepe-Lapsa
Vita Ozola
Kristaps Jaudzems
Edgars Suna
Aigars Jirgensons

European Journal of Medicinal Chemistry

Published 1 January 2019

Crick labs

Mike Blackman

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Essentiality of Plasmodium falciparum plasmepsin V

Authors (5)

Nonlawat Boonyalai
Christine R Collins
Fiona Hackett
Chrislaine Withers-Martinez
Michael Blackman

PLOS ONE

Published 5 December 2018

Crick labs

Mike Blackman

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Essential role of Plasmodium perforin-like protein 4 in ookinete midgut passage

Authors (11)

Elena Deligianni
Natalie C Silmon de Monerri
Paul J McMillan
Lucia Bertuccini
Fabiana Superti
Maria Manola
Lefteris Spanos
Christos Louis
Michael Blackman
Leann Tilley
Inga Siden-Kiamos

PLOS ONE

Published 13 August 2018

Crick labs

Mike Blackman

Full details

The actinomyosin motor drives malaria parasite red blood cell invasion but not egress

Authors (6)

Abigail Perrin
Christine R Collins
Matt Russell
Lucy Collinson
David A Baker
Michael Blackman

mBio

Published 3 July 2018

Crick labs/ facilities

Full details

Identification and validation of a novel panel of Plasmodium knowlesi biomarkers of serological exposure

Authors (10)

Lou S Herman
Kimberly Fornace
Jody Phelan
Matthew J Grigg
Nicholas M Anstey
Timothy William
Robert W Moon
Michael Blackman
Chris J Drakeley
Kevin KA Tetteh

PLoS Neglected Tropical Diseases

Published 14 June 2018

Crick labs

Mike Blackman

Full details

Plasmodium falciparum dipeptidyl aminopeptidase 3 activity is important for efficient erythrocyte invasion by the malaria parasite

Authors (7)

Christine Lehmann
Ser Ying Tan
Laura E de Vries
Ilaria Russo
Mateo I Sanchez
Daniel E Goldberg
Edgar Deu Sandoval

PLOS Pathogens

Published 16 May 2018

Crick labs

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A protease cascade regulates release of the human malaria parasite Plasmodium falciparum from host red blood cells

Authors (12)

James A Thomas
Ser Ying Tan
Claudine Bisson
Aaron Borg
Trishant R Umrekar
Fiona Hackett
[...]
Gema Vizcay-Barrena
Roland A Fleck
Bram Snijders
Helen R Saibil
Michael Blackman

Nature Microbiology

Published 1 April 2018

Crick labs/ facilities

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A reference genome and methylome for the Plasmodium knowlesi A1-H.1 line

Authors (13)

Ernest Diez Benavente
Paola Florez de Sessions
Robert W Moon
Munira Grainger
Anthony Holder
Michael Blackman
[...]
Arnab Pain
Colin J Sutherland
Martin L Hibberd
Susana Campino
Taane G Clark

International Journal for Parasitology

Published 1 March 2018

Crick labs

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A multistage antimalarial targets the plasmepsins IX and X essential for invasion and egress

Authors (12)

Paco Pino
Reto Caldelari
Budhaditya Mukherjee
Juha Vahokoski
Natacha Klages
Bohumil Maco
[...]
Michael Blackman
Inari Kursula
Volker Heussler
Mathieu Brochet
Dominique Soldati-Favre

Science

Published 27 October 2017

Crick labs

Mike Blackman

Full details

Analysis of nuclear and organellar genomes of Plasmodium knowlesi in humans reveals ancient population structure and recent recombination among host-specific subpopulations

Authors (12)

Ernest Diez Benavente
Paola Florez de Sessions
Robert W Moon
Anthony Holder
Michael Blackman
Cally Roper
[...]
Arnab Pain
Colin J Sutherland
Martin L Hibberd
Susana Campino
Taane G Clark

PLOS Genetics

Published 18 September 2017

Crick labs

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The Plasmodium falciparum pseudoprotease SERA5 regulates the kinetics and efficiency of malaria parasite egress from host erythrocytes

Authors (5)

Christine R Collins
Fiona Hackett
Jonathan Atid
Ser Ying Tan
Michael Blackman

PLOS Pathogens

Published 6 July 2017

Crick labs

Mike Blackman

Full details

Generating conditional gene knockouts in Plasmodium - a toolkit to produce stable DiCre recombinase-expressing parasite lines using CRISPR/Cas9

Authors (4)

Ellen Knuepfer
Marta Napiorkowska
Christiaan Van Ooij
Anthony Holder

Scientific Reports

Published 20 June 2017

Crick labs/ facilities

Full details

Parasitophorous vacuole poration precedes its rupture and rapid host erythrocyte cytoskeleton collapse in Plasmodium falciparum egress

Authors (12)

Victoria L Hale
Jean M Watermeyer
Fiona Hackett
Gema Vizcay-Barrena
Christiaan Van Ooij
James A Thomas
[...]
Maria Harkiolaki
Elizabeth Duke
Roland A Fleck
Michael Blackman
Helen R Saibil

Proceedings of the National Academy of Sciences of the United States of America

Published 28 March 2017

Crick labs

Mike Blackman

Full details

The Plasmodium falciparum rhoptry protein RhopH3 plays essential roles in host cell invasion and nutrient uptake

Authors (6)

Emma S Sherling
Ellen Knuepfer
Joseph A Brzostowski
Louis H Miller
Michael Blackman
Christiaan van Ooij

eLife

Published 2 March 2017

Crick labs/ facilities

Full details

Targeted deletion of a Plasmodium site-2 protease impairs life cycle progression in the mammalian host

Authors (7)

Konstantinos Kousis
Evi Goulielmaki
Anna Chalari
Chrislaine Withers-Martinez
Inga Siden-Kiamos
Kai Matuschewski
Thanasis G Loukeris

PLOS ONE

Published 20 January 2017

Crick labs

Mike Blackman

Full details

Combining traditional medicine and modern chemistry to fight malaria

Authors (1)

Christiaan van Ooij

Annals of Translational Medicine

Published 1 December 2016

Crick labs

Mike Blackman

Full details

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Blackman lab
Malaria Biochemistry Laboratory
: Publications

Lab content

Publications

Year published

Research topics

Publication type

Journal

Characterization of P. falciparum dipeptidyl aminopeptidase 3 specificity identifies differences in amino acid preferences between peptide-based substrates and covalent inhibitors

Cyclic AMP signalling controls key components of malaria parasite host cell invasion machinery

The Plasmodium berghei serine protease PbSUB1 plays an important role in male gamete egress

Phosphodiesterase beta is the master regulator of cAMP signalling during malaria parasite invasion

Peptidomimetic plasmepsin inhibitors with potent anti-malarial activity and selectivity against cathepsin D

Essentiality of Plasmodium falciparum plasmepsin V

Essential role of Plasmodium perforin-like protein 4 in ookinete midgut passage

The actinomyosin motor drives malaria parasite red blood cell invasion but not egress

Identification and validation of a novel panel of Plasmodium knowlesi biomarkers of serological exposure

Plasmodium falciparum dipeptidyl aminopeptidase 3 activity is important for efficient erythrocyte invasion by the malaria parasite

A protease cascade regulates release of the human malaria parasite Plasmodium falciparum from host red blood cells

A reference genome and methylome for the Plasmodium knowlesi A1-H.1 line

A multistage antimalarial targets the plasmepsins IX and X essential for invasion and egress

Analysis of nuclear and organellar genomes of Plasmodium knowlesi in humans reveals ancient population structure and recent recombination among host-specific subpopulations

The Plasmodium falciparum pseudoprotease SERA5 regulates the kinetics and efficiency of malaria parasite egress from host erythrocytes

Generating conditional gene knockouts in Plasmodium - a toolkit to produce stable DiCre recombinase-expressing parasite lines using CRISPR/Cas9

Parasitophorous vacuole poration precedes its rupture and rapid host erythrocyte cytoskeleton collapse in Plasmodium falciparum egress

The Plasmodium falciparum rhoptry protein RhopH3 plays essential roles in host cell invasion and nutrient uptake

Targeted deletion of a Plasmodium site-2 protease impairs life cycle progression in the mammalian host

Combining traditional medicine and modern chemistry to fight malaria

The Francis Crick Institute is a unique partnership between

Research case studies

Postdoctoral clinical fellows

Hello Brain!

News and reports

About us

Lab content

Publications

Year published

Research topics

Publication type

Journal

Publications

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