Blackman lab
Malaria Biochemistry Laboratory
: Publications

Publications

Displaying 61 - 80 of 102

Last updated : 19 April 2024 03:05

Variant exported blood-stage proteins encoded by Plasmodium multigene families are expressed in liver stages where they are exported into the parasitophorous vacuole

Authors (20)

Aurélie Fougère
Andrew P Jackson
Dafni Paraskevi Bechtsi
Joanna AM Braks
Takeshi Annoura
Jannik Fonager
[...]
Ulrike Böhme
Christiaan van Ooij
Thomas D Otto
Chris J Janse
Blandine Franke-Fayard

PLOS Pathogens

Published 16 November 2016

Crick labs

Mike Blackman

Full details

Regulation and essentiality of the StAR-related lipid transfer (START) domain-containing phospholipid transfer protein PFA0210c in malaria parasites

Authors (6)

Ross J Hill
Alessa Ringel
Ellen Knuepfer
Robert W Moon
Michael Blackman
Christiaan van Ooij

Journal of Biological Chemistry

Published 11 November 2016

Crick labs

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Host cell remodeling by pathogens: the exomembrane system in Plasmodium-infected erythrocytes

Authors (2)

Emma S Sherling
Christiaan van Ooij

FEMS Microbiology Reviews

Published 1 September 2016

Crick labs

Mike Blackman

Full details

Development and application of a simple plaque assay for the human malaria parasite Plasmodium falciparum

Authors (8)

James A Thomas
Christine R Collins
Sujaan Das
Fiona Hackett
Arnault Graindorge
Donald Bell
Edgar Deu Sandoval
Michael Blackman

PLOS ONE

Published 22 June 2016

Crick labs/ facilities

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Normocyte-binding protein required for human erythrocyte invasion by the zoonotic malaria parasite Plasmodium knowlesi

Authors (17)

Robert W Moon
Hazem Sharaf
Claire H Hastings
Yung Shwen Ho
Mridul B Nair
Zineb Rchiad
[...]
Neil Almond
Yee Ling Lau
Arnab Pain
Michael Blackman
Anthony Holder

Proceedings of the National Academy of Sciences of the United States of America

Published 28 June 2016

Crick labs

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A versatile strategy for rapid conditional genome engineering using loxP sites in a small synthetic intron in Plasmodium falciparum

Authors (6)

Matthew L Jones
Sujaan Das
Hugo Belda
Christine R Collins
Michael Blackman
Moritz Treeck

Scientific Reports

Published 19 February 2016

Crick labs

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In silico study of subtilisin-like protease 1 (SUB1) from different Plasmodium species in complex with peptidyl-difluorostatones and characterization of potent pan-SUB1 inhibitors

Authors (8)

Simone Brogi
Simone Giovani
Margherita Brindisi
Sandra Gemma
Ettore Novellino
Giuseppe Campiani
Michael Blackman
Stefania Butini

Journal of Molecular Graphics & Modelling

Published 1 March 2016

Crick labs

Mike Blackman

Full details

Fragment-based discovery of 2-aminoquinazolin-4(3H)-ones as novel class nonpeptidomimetic inhibitors of the plasmepsins I, II, and IV

Authors (12)

Dace Rasina
Martins Otikovs
Janis Leitans
Rosario Recacha
Oleksandr V Borysov
Iveta Kanepe-Lapsa
[...]
Teodors Pantelejevs
Kaspars Tars
Michael Blackman
Kristaps Jaudzems
Aigars Jirgensons

Journal of Medicinal Chemistry

Published 14 January 2016

Crick labs

Mike Blackman

Full details

A spiral scaffold underlies cytoadherent knobs in Plasmodium falciparum-infected erythrocytes

Authors (9)

Jean M Watermeyer
Victoria L Hale
Fiona Hackett
Daniel K Clare
Erin E Cutts
Ioannis Vakonakis
Roland A Fleck
Michael Blackman
Helen R Saibil

Blood

Published 21 January 2016

Crick labs

Mike Blackman

Full details

Processing of Plasmodium falciparum merozoite surface protein MSP1 activates a spectrin-binding function enabling parasite egress from RBCs

Authors (14)

Sujaan Das
Nadine Hertrich
Abigail Perrin
Chrislaine Withers-Martinez
Christine R Collins
Matthew L Jones
[...]
Helen R Saibil
Gavin J Wright
Moritz Treeck
Christian Epp
Michael Blackman

Cell Host & Microbe

Published 14 October 2015

Crick labs/ facilities

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Carbamoyl triazoles, known serine protease inhibitors, are a potent new class of antimalarials

Authors (23)

Matthew McConville
Jorge Fernández
Íñigo Angulo-Barturen
Noemi Bahamontes-Rosa
Lluis Ballell-Pages
Pablo Castañeda
[...]
Giancarlo A Biagini
Neil G Berry
Michael Blackman
Félix Calderón
Paul M O'Neill

Journal of Medicinal Chemistry

Published 27 August 2015

Crick labs

Mike Blackman

Full details

Conditional U1 gene silencing in Toxoplasma gondii

Authors (11)

Manuela S Pieperhoff
Gurman S Pall
Elena Jiménez-Ruiz
Sujaan Das
Carmen Melatti
Matthew Gow
Eleanor H Wong
Joanne Heng
Sylke Müller
Michael Blackman
Markus Meissner

PLOS ONE

Published 19 June 2015

Crick labs

Mike Blackman

Full details

Plasmodium falciparum subtilisin-like protease 1: discovery of potent difluorostatone-based inhibitors

Authors (9)

Simone Giovani
Maria Penzo
Stefania Butini
Margherita Brindisi
Sandra Gemma
Ettore Novellino
Giuseppe Campiani
Michael Blackman
Simone Brogi

RSC Advances

Published 19 February 2015

Crick labs

Mike Blackman

Full details

Plasmodium falciparum SERA5 plays a non-enzymatic role in the malarial asexual blood-stage lifecycle

Authors (11)

Robert Stallmach
Manoli Kavishwar
Chrislaine Withers-Martinez
Fiona Hackett
Christine R Collins
Steven A Howell
Sharon Yeoh
Ellen Knuepfer
Avshalom J Atid
Anthony Holder
Michael Blackman

Molecular Microbiology

Published 1 April 2015

Crick labs/ facilities

Full details

Quinoxaline-based inhibitors of malarial protease PfSUB1

Authors (7)

SS Kher
M Penzo
S Fulle
JP Ebejer
PW Finn
Michael Blackman
A Jirgensons

Chemistry of Heterocyclic Compounds

Published 1 January 2015

Crick labs

Mike Blackman

Full details

Substrate derived peptidic α-ketoamides as inhibitors of the malarial protease PfSUB1

Authors (6)

Samir S Kher
Maria Penzo
Simone Fulle
Paul W Finn
Michael Blackman
Aigars Jirgensons

Bioorganic & Medicinal Chemistry Letters

Published 7 August 2014

Crick labs

Mike Blackman

Full details

Rational design of the first difluorostatone-based PfSUB1 inhibitors

Authors (10)

Simone Giovani
Maria Penzo
Simone Brogi
Margherita Brindisi
Sandra Gemma
Ettore Novellino
Luisa Savini
Michael Blackman
Giuseppe Campiani
Stefania Butini

Bioorganic & Medicinal Chemistry Letters

Published 23 May 2014

Crick labs

Mike Blackman

Full details

Plasmepsin inhibitory activity and structure-guided optimization of a potent hydroxyethylamine-based antimalarial hit

Authors (12)

K Jaudzems
K Tars
G Maurops
N Ivdra
M Otikovs
J Leitans
[...]
I Domraceva
I Mutule
P Trapencieris
Michael Blackman
A Jirgensons

ACS Medicinal Chemistry Letters

Published 1 April 2014

Crick labs

Mike Blackman

Full details

Cyclic nucleotide (cAMP and cGMP) assays and capture ELISA for quantitative analysis of Plasmodium falciparum blood-stage egress

Authors (4)

Fiona Hackett
Christine R Collins
Malcolm Strath
Michael Blackman

Bio-Protocol

Published 5 March 2014

Crick labs

Mike Blackman

Full details

Human red blood cell-adapted Plasmodium knowlesi parasites: a new model system for malaria research

Authors (6)

Christof Grüring
Robert W Moon
Caeul Lim
Anthony Holder
Michael Blackman
Manoj T Duraisingh

Cellular Microbiology

Published 9 February 2014

Crick labs

Full details

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Blackman lab
Malaria Biochemistry Laboratory
: Publications

Lab content

Publications

Year published

Research topics

Publication type

Journal

Variant exported blood-stage proteins encoded by Plasmodium multigene families are expressed in liver stages where they are exported into the parasitophorous vacuole

Regulation and essentiality of the StAR-related lipid transfer (START) domain-containing phospholipid transfer protein PFA0210c in malaria parasites

Host cell remodeling by pathogens: the exomembrane system in Plasmodium-infected erythrocytes

Development and application of a simple plaque assay for the human malaria parasite Plasmodium falciparum

Normocyte-binding protein required for human erythrocyte invasion by the zoonotic malaria parasite Plasmodium knowlesi

A versatile strategy for rapid conditional genome engineering using loxP sites in a small synthetic intron in Plasmodium falciparum

In silico study of subtilisin-like protease 1 (SUB1) from different Plasmodium species in complex with peptidyl-difluorostatones and characterization of potent pan-SUB1 inhibitors

Fragment-based discovery of 2-aminoquinazolin-4(3H)-ones as novel class nonpeptidomimetic inhibitors of the plasmepsins I, II, and IV

A spiral scaffold underlies cytoadherent knobs in Plasmodium falciparum-infected erythrocytes

Processing of Plasmodium falciparum merozoite surface protein MSP1 activates a spectrin-binding function enabling parasite egress from RBCs

Carbamoyl triazoles, known serine protease inhibitors, are a potent new class of antimalarials

Conditional U1 gene silencing in Toxoplasma gondii

Plasmodium falciparum subtilisin-like protease 1: discovery of potent difluorostatone-based inhibitors

Plasmodium falciparum SERA5 plays a non-enzymatic role in the malarial asexual blood-stage lifecycle

Quinoxaline-based inhibitors of malarial protease PfSUB1

Substrate derived peptidic α-ketoamides as inhibitors of the malarial protease PfSUB1

Rational design of the first difluorostatone-based PfSUB1 inhibitors

Plasmepsin inhibitory activity and structure-guided optimization of a potent hydroxyethylamine-based antimalarial hit

Cyclic nucleotide (cAMP and cGMP) assays and capture ELISA for quantitative analysis of Plasmodium falciparum blood-stage egress

Human red blood cell-adapted Plasmodium knowlesi parasites: a new model system for malaria research

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Research case studies

Postdoctoral clinical fellows

Hello Brain!

News and reports

About us

Lab content

Publications

Year published

Research topics

Publication type

Journal

Publications

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