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Goehring lab
Polarity and Patterning Networks Laboratory
: Publications

An asymmetric pattern of PAR proteins emerges in the fertilized egg of the nematode worm C. elegans, that defines the anterior (head) to posterior (tail) axis of the embryo, and reorganizes the cell’s interior so that it can divide into two daughter cells with different sizes and fates. A similar patterning process plays key roles in the organization of cells within the human embryo and many different types of cells in our bodies.

Publications

Displaying 1 - 20 of 26

Last updated : 02 October 2023 02:40

Cleavage furrow-directed cortical flows bias PAR polarization pathways to link cell polarity to cell division

Authors (7)

Current Biology

Published 19 September 2023

Crick labs

Nathan Goehring

Design principles for selective polarization of PAR proteins by cortical flows

Authors (9)

The Journal of Cell Biology

Published 7 August 2023

Crick labs

Nathan Goehring

An analog sensitive allele permits rapid and reversible chemical inhibition of PKC-3 activity in C. elegans

Authors (4)

MicroPublication Biology

Published 4 August 2022

Crick labs

Nathan Goehring

SAIBR: a simple, platform-independent method for spectral autofluorescence correction

Authors (8)

Published 15 July 2022

Crick labs/ facilities

Objective comparison of methods to decode anomalous diffusion

Authors (34)

Gorka Muñoz-Gil
Giovanni Volpe
Miguel Angel Garcia-March
Erez Aghion
Aykut Argun
Chang Beom Hong
[...]
Giorgio Volpe
Artur Widera
Maciej Lewenstein
Ralf Metzler
Carlo Manzo

Nature Communications

Published 29 October 2021

Crick labs

Nathan Goehring

The first steps in the life of a worm: Themes and variations in asymmetric division in C. elegans and other nematodes

Authors (2)

Marie Delattre
Nathan Goehring

Current Topics in Developmental Biology

Published 1 January 2021

Crick labs

Nathan Goehring

Intracellular morphogens: Specifying patterns at the subcellular scale

Authors (2)

Lars Hubatsch
Nathan Goehring

Current Topics in Developmental Biology

Published 1 January 2020

Crick labs

Nathan Goehring

Patterning and polarization of cells by intracellular flows

Authors (3)

Current Opinion in Cell Biology

Published 1 February 2020

Crick labs

Nathan Goehring

A cell-size threshold limits cell polarity and asymmetric division potential

Authors (7)

Published 1 October 2019

Crick labs

Nathan Goehring

Switching states: dynamic remodelling of polarity complexes as a toolkit for cell polarization

Authors (2)

Florent Peglion
Nathan Goehring

Current Opinion in Cell Biology

Published 1 October 2019

Crick labs

Nathan Goehring

Anterior-enriched filopodia create appearance of asymmetric membrane microdomains in polarizing C. elegans zygotes

Authors (7)

Nisha Hirani
Rukshala Illukkumbura
Tom Bland
Grégoire Mathonnet
Delphine Suhner
Anne-Cecile Reymann
Nathan Goehring

Journal of Cell Science

Published 15 July 2019

Crick labs

Nathan Goehring

Regulated activation of the PAR polarity network ensures a timely and specific response to spatial cues

Authors (7)

Current Biology

Published 17 June 2019

Crick labs

Nathan Goehring

Guiding self-organized pattern formation in cell polarity establishment

Authors (7)

Peter Gross
K Vijay Kumar
Nathan Goehring
Justin S Bois
Carsten Hoege
Frank Jülicher
Stephan W Grill

Published 1 March 2019

Crick labs

Nathan Goehring

aPKC cycles between functionally distinct PAR protein assemblies to drive cell polarity

Authors (12)

Josana Rodriguez
Florent Peglion
Jack Martin
Lars Hubatsch
Jake Reich
Nisha Hirani
[...]
Jon Roffey
Artur Ribeiro Fernandes
Daniel St Johnston
Julie Ahringer
Nathan Goehring

Developmental Cell

Published 21 August 2017

Crick labs

Nathan Goehring

Intracellular scaling mechanisms

Authors (2)

Simone Reber
Nathan Goehring

Cold Spring Harbor Perspectives in Biology

Published 7 August 2015

Crick labs

Nathan Goehring

PAR polarity: from complexity to design principles

Authors (1)

Nathan Goehring

Experimental Cell Research

Published 1 November 2014

Crick labs

Nathan Goehring

Parameter-space topology of models for cell polarity

Authors (5)

PK Trong
EM Nicola
Nathan Goehring
KV Kumar
SW Grill

New Journal of Physics

Published 1 January 2014

Crick labs

Nathan Goehring

Cell polarity: mechanochemical patterning

Authors (2)

Nathan Goehring
Stephan W Grill

Trends in Cell Biology

Published 1 February 2013

Crick labs

Nathan Goehring

Organelle growth control through limiting pools of cytoplasmic components

Authors (2)

Nathan Goehring
Anthony A Hyman

Current Biology

Published 8 May 2012

Crick labs

Nathan Goehring

Polarization of PAR proteins by advective triggering of a pattern-forming system

Authors (7)

Nathan Goehring
Philipp Khuc Trong
Justin S Bois
Debanjan Chowdhury
Ernesto M Nicola
Anthony A Hyman
Stephan W Grill

Published 25 November 2011

Crick labs

Nathan Goehring