Publications

Expanded directly binds conserved regions of Fat to restrain growth via the Hippo pathway

Authors (9)

Alexander D Fulford
Leonie Enderle
Jannette Rusch
Didier Hodzic
Maxine Holder
Alex Earl
Robin Hyunseo Oh
Nicolas Tapon
Helen McNeill

The Journal of Cell Biology

Published 1 May 2023

Crick labs

Nic Tapon

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Co-option of epidermal cells enables touch sensing

Authors (7)

Nature Cell Biology

Published 1 April 2023

Crick labs/ facilities

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Phosphorylation-linked complex profiling identifies assemblies required for Hippo signal integration

Authors (14)

Federico Uliana
Rodolfo Ciuffa
Ranjan Mishra
Andrea Fossati
Fabian Frommelt
Sabrina Keller
[...]
Nevena Srejic
Matthias Peter
Nicolas Tapon
Ruedi Aebersold
Matthias Gstaiger

Molecular Systems Biology

Published 12 April 2023

Crick labs

Nic Tapon

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Photoablation at single cell resolution and its application in the Drosophila epidermis and peripheral nervous system

Authors (3)

Frontiers in Physiology

Published 4 January 2023

Crick labs/ facilities

Full details

ECM degradation in the Drosophila abdominal epidermis initiates tissue growth that ceases with rapid cell-cycle exit

Authors (11)

Current Biology

Published 28 March 2022

Crick labs/ facilities

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RASSF8-mediated transport of Echinoid via the exocyst promotes Drosophila wing elongation and epithelial ordering

Authors (8)

Development

Published 15 October 2021

Crick labs/ facilities

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Casein kinase 1 family proteins promote Slimb-dependent Expanded degradation

Authors (6)

Alexander D Fulford
Maxine Holder
David Frith
Bram Snijders
Nicolas Tapon
Paulo S Ribeiro

eLife

Published 30 September 2019

Crick labs/ facilities

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Hippo signalling during development

Authors (2)

Development

Published 16 September 2019

Crick labs

Nic Tapon

Full details

ASPP proteins discriminate between PP1 catalytic subunits through their SH3 domain and the PP1 C-tail

Authors (15)

M Teresa Bertran
Stephane Mouilleron
Yanxiang Zhou
Rakhi Bajaj
Federico Uliana
Ganesan Senthil Kumar
[...]
Nicola O'Reilly
Matthias Gstaiger
Rebecca Page
Wolfgang Peti
Nicolas Tapon

Nature Communications

Published 15 February 2019

Crick labs/ facilities

Full details

Stability and roughness of interfaces in mechanically regulated tissues

Authors (2)

Physical Review Letters

Published 7 December 2018

Crick labs

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Apical and basal matrix remodeling control epithelial morphogenesis

Authors (9)

Maria Carmen Diaz De La Loza
RP Ray
P Ganguly
S Alt
John Davis
A Hoppe
Nicolas Tapon
Guillaume Salbreux
BJ Thompson

Developmental Cell

Published 2 July 2018

Crick labs

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Mechanical strain regulates the Hippo pathway in Drosophila

Authors (6)

Development

Published 8 March 2018

Crick labs/ facilities

Full details

Upstairs, downstairs: spatial regulation of Hippo signalling

Authors (3)

Alexander Fulford
Nicolas Tapon
Paulo S Ribeiro

Current Opinion in Cell Biology

Published 16 November 2017

Crick labs

Nic Tapon

Full details

Stable MOB1 interaction with Hippo/MST is not essential for development and tissue growth control

Authors (15)

Yavuz Kulaberoglu
Kui Lin
Maxine Holder
Zhongchao Gai
Marta Gomez
Belul Assefa Shifa
[...]
Ewan St John Smith
Ivana Bjedov
Nicolas Tapon
Geng Wu
Alexander Hergovich

Nature Communications

Published 25 September 2017

Crick labs

Nic Tapon

Full details

Meru couples planar cell polarity with apical-basal polarity during asymmetric cell division

Authors (6)

Jennifer J Banerjee
Birgit Aerne
Maxine Holder
Simon Hauri
Matthias Gstaiger
Nicolas Tapon

eLife

Published 30 June 2017

Crick labs/ facilities

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EpiTools: an open-source image analysis toolkit for quantifying epithelial growth dynamics

Authors (8)

Davide Heller
Andreas Hoppe
Simon Restrepo
Lorenzo Gatti
Alexander L Tournier
Nicolas Tapon
Konrad Basler
Yanlan Mao

Developmental Cell

Published 11 January 2016

Crick labs

Nic Tapon

Full details

The Hippo pathway core cassette regulates asymmetric cell division

Authors (6)

Alyona Keder
Noemí Rives-Quinto
Birgit Aerne
Maribel Franco
Nicolas Tapon
Ana Carmena

Current Biology

Published 2 November 2015

Crick labs

Nic Tapon

Full details

Differential control of Yorkie activity by LKB1/AMPK and the Hippo/Warts cascade in the central nervous system

Authors (3)

Proceedings of the National Academy of Sciences of the United States of America

Published 15 September 2015

Crick labs/ facilities

Full details

Patterned anchorage to the apical extracellular matrix defines tissue shape in the developing appendages of Drosophila

Authors (7)

Robert P Ray
Alexis Matamoro-Vidal
Paulo S Ribeiro
Nicolas Tapon
David Houle
Isaac Salazar-Ciudad
Barry J Thompson

Developmental Cell

Published 10 August 2015

Crick labs

Full details

Hippo stabilises its adaptor Salvador by antagonising the HECT ubiquitin ligase Herc4

Authors (4)

Birgit Aerne
Ieva Gailite
David Sims
Nicolas Tapon

PLOS ONE

Published 30 June 2015

Crick labs

Nic Tapon

Full details

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Expanded directly binds conserved regions of Fat to restrain growth via the Hippo pathway

Co-option of epidermal cells enables touch sensing

Phosphorylation-linked complex profiling identifies assemblies required for Hippo signal integration

Photoablation at single cell resolution and its application in the Drosophila epidermis and peripheral nervous system

ECM degradation in the Drosophila abdominal epidermis initiates tissue growth that ceases with rapid cell-cycle exit

RASSF8-mediated transport of Echinoid via the exocyst promotes Drosophila wing elongation and epithelial ordering

Casein kinase 1 family proteins promote Slimb-dependent Expanded degradation

Hippo signalling during development

ASPP proteins discriminate between PP1 catalytic subunits through their SH3 domain and the PP1 C-tail

Stability and roughness of interfaces in mechanically regulated tissues

Apical and basal matrix remodeling control epithelial morphogenesis

Mechanical strain regulates the Hippo pathway in Drosophila

Upstairs, downstairs: spatial regulation of Hippo signalling

Stable MOB1 interaction with Hippo/MST is not essential for development and tissue growth control

Meru couples planar cell polarity with apical-basal polarity during asymmetric cell division

EpiTools: an open-source image analysis toolkit for quantifying epithelial growth dynamics

The Hippo pathway core cassette regulates asymmetric cell division

Differential control of Yorkie activity by LKB1/AMPK and the Hippo/Warts cascade in the central nervous system

Patterned anchorage to the apical extracellular matrix defines tissue shape in the developing appendages of Drosophila

Hippo stabilises its adaptor Salvador by antagonising the HECT ubiquitin ligase Herc4

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