Luscombe lab

Bioinformatics and Computational Biology Laboratory

: Gene regulation in disease states

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We will apply our basic knowledge of gene regulation to disease systems. There are indications that bacterial infections cause changes to the host's regulatory system, so affecting expression patterns. We have initiated collaborations with Richard Hayward (University College London) to apply genomic techniques to investigate the prevalence of these effects, and the influence they have on the progression of bacterial infections.