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Breadcrumb Patricia Barral Barral lab Immune Responses to Lipids Laboratory : Publications Lab contentLab contentIn this section Overview Areas of interest Publications Members Vacancies Image shows a section of intestinal tissue (blue) with mucus-producing cells (goblet cells, yellow). Toggle to view hero caption PublicationsYear published2023 (2)2022 (1)2020 (1)2019 (1)2018 (2)2017 (1)2013 (1)2012 (4)2010 (3) Facet Year publishedResearch topicsImmunology (8)Model Organisms (8)Tumour Biology (3)Chemical Biology & High Throughput (2)Computational & Systems Biology (2)Genetics & Genomics (2)Genome Integrity & Repair (2)Human Biology & Physiology (2)Infectious Disease (2)Imaging (1)Microfabrication & Bioengineering (1) Facet Research topicsPublication typeJournal article (16)Primary research (12)Review (2)Commentary (1)Method (1) Facet Publication typeJournalEMBO Journal (2)Nature Immunology (2)Cell (1)Cell Reports (1)Current Opinion in Immunology (1)eLife (1)EMBO Reports (1)FEBS Journal (1)Immunity (1)Journal of Experimental Medicine (1)Journal of Visualized Experiments (1)Molecular Cell (1)Nature Communications (1)Science (1) Facet Journal Publications Displaying 1 - 16 of 16Last updated : 30 November 2023 02:25 Interplay between CXCR4 and CCR2 regulates bone marrow exit of dendritic cell progenitors Authors (11)Mariana Pereira Da CostaCarlos Munoz MinuttiCecile PiotEvangelos GiampazoliasAna Matos Cardoso Da SilvaMar Cabeza CabrerizoNeil RogersMarta de Lebrusant FernandezChrysante IliakisAndreas WackCaetano Reis e Sousa Cell Reports Published 29 August 2023 Crick labs/ facilitiesAndreas WackCaetano Reis e SousaPatricia BarralFlow CytometryBiological Research FacilityFull details Type I interferons drive MAIT cell functions againstbacterial pneumonia Authors (12)Juan Carlos Lopez Rodriguez Steven J Hancock Kelin LiStefania Crotta Christopher Barrington Alejandro Suárez-Bonnet[...] Jeffrey AubéAndreas Wack Paul Klenerman Jose A BengoecheaPatricia Barral Journal of Experimental Medicine Published 2 October 2023 Crick labs/ facilitiesAndreas WackPatricia BarralExperimental HistopathologyBioinformatics and BiostatisticsLight MicroscopyFlow CytometryBiological Research FacilityAdvanced SequencingFull details CD1d-dependent rewiring of lipid metabolism in macrophages regulates innate immune responses Authors (10)Phillip BraileyLauren EvansJuan Carlos Lopez Rodriguez Anthony Sinadinos Victoria TyrrelGavin Kelly Valerie O'Donnell Peter Ghazal Susan JohnPatricia Barral Nature Communications Published 7 November 2022 Crick labs/ facilitiesPatricia BarralBioinformatics and BiostatisticsLight MicroscopyFlow CytometryBiological Research FacilityAdvanced SequencingFull details NKT cells and the regulation of intestinal immunity: a two-way street Authors (3)Phillip BraileyMarta de Lebrusant FernandezPatricia Barral FEBS Journal Published 1 May 2020 Crick labsPatricia BarralFull details Tissue-specific shaping of the TCR repertoire and antigen specificity of iNKT cells Authors (11)Rebeca Jimeno LumerasMarta de Lebrusant Fernandez Christian Margreitter Beth Lucas Natacha VeerapenGavin Kelly Gurdyal S Besra Franca Fraternali Jo Spencer Graham AndersonPatricia Barral eLife Published 16 December 2019 Crick labs/ facilitiesPatricia BarralBioinformatics and BiostatisticsFull details Quantitative polymerase chain reaction-based analyses of murine intestinal microbiota after oral antibiotic treatment Authors (3)Rebeca Jimeno LumerasPhillip BraileyPatricia Barral Journal of Visualized Experiments Published 17 November 2018 Crick labsPatricia BarralFull details CD1d-mediated lipid presentation by CD11c+ cells regulates intestinal homeostasis Authors (8) Julia Sáez de Guinoa Rebeca Jimeno Mauro Gaya David Kipling María José Garzón Deborah Dunn-Walters Carles UbedaPatricia Barral EMBO Journal Published 1 March 2018 Crick labsPatricia BarralFull details Initiation of antiviral B cell immunity relies on innate signals from spatially positioned NKT cells Authors (18) Mauro GayaPatricia Barral Marianne Burbage Shweta AggarwalBeatriz Montaner Andrew Warren Navia[...] Dan H Barouch Alex K Shalek Andreas Bruckbauer Jessica Strid Facundo D Batista Cell Published 25 January 2018 Crick labs/ facilitiesPatricia BarralFlow CytometryBiological Research FacilityFull details RIF1 is essential for 53BP1-dependent nonhomologous end joining and suppression of DNA double-strand break resection Authors (10) J Ross ChapmanPatricia Barral Jean-Baptiste Vannier Valérie Borel Martin Steger Antonia Tomas-Loba Alessandro A Sartori Ian R Adams Facundo D BatistaSimon Boulton Molecular Cell Published 7 March 2013 Crick labsSimon BoultonPatricia BarralFull details The location of splenic NKT cells favours their rapid activation by blood-borne antigen Authors (5)Patricia Barral María Dolores Sánchez-Niño Nico van Rooijen Vincenzo Cerundolo Facundo D Batista EMBO Journal Published 16 May 2012 Crick labsPatricia BarralFull details Neutrophils—the unexpected helpers of B-cell activation Authors (3) Naomi E HarwoodPatricia Barral Facundo D Batista EMBO Reports Published 1 February 2012 Crick labsPatricia BarralFull details Asymmetric segregation of polarized antigen on B cell division shapes presentation capacity Authors (10) Olivier Thaunat Aitor G GranjaPatricia Barral Andrew FilbyBeatriz MontanerLucy Collinson Nuria Martinez-Martin Naomi E Harwood Andreas Bruckbauer Facundo D Batista Science Published 27 January 2012 Crick labs/ facilitiesPatricia BarralFlow CytometryElectron MicroscopyFull details Identification of Bcl-6-dependent follicular helper NKT cells that provide cognate help for B cell responses Authors (15) Pheh-Ping ChangPatricia Barral Jessica Fitch Alvin Pratama Cindy S Ma Axel Kallies[...] Stephen L Nutt Robert Brink Dale I Godfrey Facundo D BatistaCarola Vinuesa Nature Immunology Published 1 January 2012 Crick labsPatricia BarralFull details Synthetic iNKT cell-agonists as vaccine adjuvants — finding the balance Authors (3) Vincenzo CerundoloPatricia Barral Facundo D Batista Current Opinion in Immunology Published 1 June 2010 Crick labsPatricia BarralFull details CD169+ macrophages present lipid antigens to mediate early activation of iNKT cells in lymph nodes Authors (7)Patricia Barral Paolo Polzella Andreas Bruckbauer Nico van Rooijen Gurdyal S Besra Vincenzo Cerundolo Facundo D Batista Nature Immunology Published 1 April 2010 Crick labsPatricia BarralFull details The membrane skeleton controls diffusion dynamics and signaling through the B cell receptor Authors (8) Bebhinn Treanor David Depoil Aitor Gonzalez-GranjaPatricia Barral Michele Weber Omer Dushek Andreas Bruckbauer Facundo D Batista Immunity Published 26 February 2010 Crick labsPatricia BarralFull details Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Interplay between CXCR4 and CCR2 regulates bone marrow exit of dendritic cell progenitors Authors (11)Mariana Pereira Da CostaCarlos Munoz MinuttiCecile PiotEvangelos GiampazoliasAna Matos Cardoso Da SilvaMar Cabeza CabrerizoNeil RogersMarta de Lebrusant FernandezChrysante IliakisAndreas WackCaetano Reis e Sousa Cell Reports Published 29 August 2023 Crick labs/ facilitiesAndreas WackCaetano Reis e SousaPatricia BarralFlow CytometryBiological Research FacilityFull details
Type I interferons drive MAIT cell functions againstbacterial pneumonia Authors (12)Juan Carlos Lopez Rodriguez Steven J Hancock Kelin LiStefania Crotta Christopher Barrington Alejandro Suárez-Bonnet[...] Jeffrey AubéAndreas Wack Paul Klenerman Jose A BengoecheaPatricia Barral Journal of Experimental Medicine Published 2 October 2023 Crick labs/ facilitiesAndreas WackPatricia BarralExperimental HistopathologyBioinformatics and BiostatisticsLight MicroscopyFlow CytometryBiological Research FacilityAdvanced SequencingFull details
CD1d-dependent rewiring of lipid metabolism in macrophages regulates innate immune responses Authors (10)Phillip BraileyLauren EvansJuan Carlos Lopez Rodriguez Anthony Sinadinos Victoria TyrrelGavin Kelly Valerie O'Donnell Peter Ghazal Susan JohnPatricia Barral Nature Communications Published 7 November 2022 Crick labs/ facilitiesPatricia BarralBioinformatics and BiostatisticsLight MicroscopyFlow CytometryBiological Research FacilityAdvanced SequencingFull details
NKT cells and the regulation of intestinal immunity: a two-way street Authors (3)Phillip BraileyMarta de Lebrusant FernandezPatricia Barral FEBS Journal Published 1 May 2020 Crick labsPatricia BarralFull details
Tissue-specific shaping of the TCR repertoire and antigen specificity of iNKT cells Authors (11)Rebeca Jimeno LumerasMarta de Lebrusant Fernandez Christian Margreitter Beth Lucas Natacha VeerapenGavin Kelly Gurdyal S Besra Franca Fraternali Jo Spencer Graham AndersonPatricia Barral eLife Published 16 December 2019 Crick labs/ facilitiesPatricia BarralBioinformatics and BiostatisticsFull details
Quantitative polymerase chain reaction-based analyses of murine intestinal microbiota after oral antibiotic treatment Authors (3)Rebeca Jimeno LumerasPhillip BraileyPatricia Barral Journal of Visualized Experiments Published 17 November 2018 Crick labsPatricia BarralFull details
CD1d-mediated lipid presentation by CD11c+ cells regulates intestinal homeostasis Authors (8) Julia Sáez de Guinoa Rebeca Jimeno Mauro Gaya David Kipling María José Garzón Deborah Dunn-Walters Carles UbedaPatricia Barral EMBO Journal Published 1 March 2018 Crick labsPatricia BarralFull details
Initiation of antiviral B cell immunity relies on innate signals from spatially positioned NKT cells Authors (18) Mauro GayaPatricia Barral Marianne Burbage Shweta AggarwalBeatriz Montaner Andrew Warren Navia[...] Dan H Barouch Alex K Shalek Andreas Bruckbauer Jessica Strid Facundo D Batista Cell Published 25 January 2018 Crick labs/ facilitiesPatricia BarralFlow CytometryBiological Research FacilityFull details
RIF1 is essential for 53BP1-dependent nonhomologous end joining and suppression of DNA double-strand break resection Authors (10) J Ross ChapmanPatricia Barral Jean-Baptiste Vannier Valérie Borel Martin Steger Antonia Tomas-Loba Alessandro A Sartori Ian R Adams Facundo D BatistaSimon Boulton Molecular Cell Published 7 March 2013 Crick labsSimon BoultonPatricia BarralFull details
The location of splenic NKT cells favours their rapid activation by blood-borne antigen Authors (5)Patricia Barral María Dolores Sánchez-Niño Nico van Rooijen Vincenzo Cerundolo Facundo D Batista EMBO Journal Published 16 May 2012 Crick labsPatricia BarralFull details
Neutrophils—the unexpected helpers of B-cell activation Authors (3) Naomi E HarwoodPatricia Barral Facundo D Batista EMBO Reports Published 1 February 2012 Crick labsPatricia BarralFull details
Asymmetric segregation of polarized antigen on B cell division shapes presentation capacity Authors (10) Olivier Thaunat Aitor G GranjaPatricia Barral Andrew FilbyBeatriz MontanerLucy Collinson Nuria Martinez-Martin Naomi E Harwood Andreas Bruckbauer Facundo D Batista Science Published 27 January 2012 Crick labs/ facilitiesPatricia BarralFlow CytometryElectron MicroscopyFull details
Identification of Bcl-6-dependent follicular helper NKT cells that provide cognate help for B cell responses Authors (15) Pheh-Ping ChangPatricia Barral Jessica Fitch Alvin Pratama Cindy S Ma Axel Kallies[...] Stephen L Nutt Robert Brink Dale I Godfrey Facundo D BatistaCarola Vinuesa Nature Immunology Published 1 January 2012 Crick labsPatricia BarralFull details
Synthetic iNKT cell-agonists as vaccine adjuvants — finding the balance Authors (3) Vincenzo CerundoloPatricia Barral Facundo D Batista Current Opinion in Immunology Published 1 June 2010 Crick labsPatricia BarralFull details
CD169+ macrophages present lipid antigens to mediate early activation of iNKT cells in lymph nodes Authors (7)Patricia Barral Paolo Polzella Andreas Bruckbauer Nico van Rooijen Gurdyal S Besra Vincenzo Cerundolo Facundo D Batista Nature Immunology Published 1 April 2010 Crick labsPatricia BarralFull details
The membrane skeleton controls diffusion dynamics and signaling through the B cell receptor Authors (8) Bebhinn Treanor David Depoil Aitor Gonzalez-GranjaPatricia Barral Michele Weber Omer Dushek Andreas Bruckbauer Facundo D Batista Immunity Published 26 February 2010 Crick labsPatricia BarralFull details