Research case studies Explore a selection of reports that spotlight particular areas of research at the Crick over the past five years.
Postdoctoral clinical fellows Opportunities for postdoctoral clinicians to consolidate their research experience.
Breadcrumb Peter Ratcliffe Ratcliffe lab Hypoxia Biology Laboratory : Publications Lab contentLab contentIn this section Overview Areas of interest Publications Members Vacancies Cell proliferation (blue nuclei) with excessive vascularisation (in red): early stage cancer in a hypoxic state. Toggle to view hero caption PublicationsYear published (-)2018 (2) Facet Year publishedResearch topicsBiochemistry & Proteomics (2)Cell Biology (2)Metabolism (2)Signalling & Oncogenes (2) Facet Research topicsPublication typeJournal article (2)Primary research (2) Facet Publication typeJournalJournal of Physiology (1)Nature Chemical Biology (1) Facet Journal Publications Displaying 1 - 2 of 2Last updated : 20 April 2024 02:53 PHD2 inactivation in Type I cells drives HIF-2α dependent multilineage hyperplasia and the formation of paraganglioma-like carotid bodies Authors (13) James W FieldingEmma Hodson Xiaotong Cheng David JP Ferguson Luise Eckardt Julie Adam[...] Indrika Ratnayaka Christopher W Pugh Keith J BucklerPeter Ratcliffe Tammie Bishop Journal of Physiology Published 14 September 2018 Crick labsPeter RatcliffeFull details The Jumonji-C oxygenase JMJD7 catalyzes (3S)-lysyl hydroxylation of TRAFAC GTPases Authors (23) Suzana Markolovic Qinqin Zhuang Sarah E Wilkins Charlotte D Eaton Martine I Abboud Maximiliano J Katz[...] Roman Fischer Pablo Wappner Rasheduzzaman Chowdhury Mathew L Coleman Christopher J Schofield Nature Chemical Biology Published 18 June 2018 Crick labsKaren VousdenPeter RatcliffeFull details Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
PHD2 inactivation in Type I cells drives HIF-2α dependent multilineage hyperplasia and the formation of paraganglioma-like carotid bodies Authors (13) James W FieldingEmma Hodson Xiaotong Cheng David JP Ferguson Luise Eckardt Julie Adam[...] Indrika Ratnayaka Christopher W Pugh Keith J BucklerPeter Ratcliffe Tammie Bishop Journal of Physiology Published 14 September 2018 Crick labsPeter RatcliffeFull details
The Jumonji-C oxygenase JMJD7 catalyzes (3S)-lysyl hydroxylation of TRAFAC GTPases Authors (23) Suzana Markolovic Qinqin Zhuang Sarah E Wilkins Charlotte D Eaton Martine I Abboud Maximiliano J Katz[...] Roman Fischer Pablo Wappner Rasheduzzaman Chowdhury Mathew L Coleman Christopher J Schofield Nature Chemical Biology Published 18 June 2018 Crick labsKaren VousdenPeter RatcliffeFull details