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Ratcliffe lab
Hypoxia Biology Laboratory
: Publications

Publications

Displaying 1 - 7 of 7

Last updated : 19 April 2024 02:32

Co-incidence of RCC-susceptibility polymorphisms with HIF cis-acting sequences supports a pathway tuning model of cancer

Authors (10)

Virginia Schmid
Veronique N Lafleur
Olivia Lombardi
Ran Li
Rafik Salama
Leandro Colli
Hani Choudhry
Stephen Chanock
Peter Ratcliffe
David R Mole

Scientific Reports

Published 10 December 2019

Crick labs

Peter Ratcliffe

Structure-activity relationship and crystallographic studies on 4-hydroxypyrimidine HIF prolyl hydroxylase domain inhibitors

Authors (13)

James P Holt-Martyn
Rasheduzzaman Chowdhury
Anthony Tumber
Tzu-Lan Yeh
Martine I Abboud
Kerstin Lippl
[...]
Jr Figg
Michael A McDonough
Christopher W Pugh
Peter Ratcliffe
Christopher J Schofield

Published 5 February 2020

Crick labs

Peter Ratcliffe

Lack of activity of recombinant HIF prolyl hydroxylases (PHDs) on reported non-HIF substrates

Authors (11)

Matthew Cockman
Kerstin Lippl
Ya-Min Tian
Hamish Pegg
William D Figg
Martine I Abboud
Raphael Heilig
Roman Fischer
Johanna Myllyharju
Christopher J Schofield
Peter Ratcliffe

eLife

Published 10 September 2019

Crick labs/ facilities

Mechanisms of hypoxia signalling: new implications for nephrology

Authors (2)

Johannes Schödel
Peter Ratcliffe

Nature Reviews Nephrology

Published 1 October 2019

Crick labs

Peter Ratcliffe

Conserved N-terminal cysteine dioxygenases transduce responses to hypoxia in animals and plants

Authors (10)

Norma Masson
Thomas P Keeley
Beatrice Giuntoli
Mark D White
Mikel Lavilla Puerta
Pierdomenico Perata
Richard J Hopkinson
Emily Flashman
Francesco Licausi
Peter Ratcliffe

Published 5 July 2019

Crick labs

Peter Ratcliffe

Systemic silencing of Phd2 causes reversible immune regulatory dysfunction

Authors (25)

Atsushi Yamamoto
Joanna Hester
Philip S Macklin
Kento Kawai
Masateru Uchiyama
Daniel Biggs
[...]
Cheryl L Scudamore
Elizabeth Soilleux
Fadi Issa
Peter Ratcliffe
Chris W Pugh

Journal of Clinical Investigation

Published 3 September 2019

Crick labs

Peter Ratcliffe

Inherent DNA-binding specificities of the HIF-1α and HIF-2α transcription factors in chromatin

Authors (11)

James A Smythies
Min Sun
Norma Masson
Rafik Salama
Peter D Simpson
Elizabeth Murray
Viviana Neumann
Matthew Cockman
Hani Choudhry
Peter Ratcliffe
David R Mole

Published 1 January 2019

Crick labs

Peter Ratcliffe