Publications

Characterization of Nigerian breast cancer reveals prevalent homologous recombination deficiency and aggressive molecular features

Authors (54)

Jason J Pitt
Markus Riester
Yonglan Zheng
Toshio F Yoshimatsu
Ayodele Sanni
Olayiwola Oluwasola
[...]
Nasiru Ibrahim
Kevin P White
Dezheng Huo
Olufunmilayo I Olopade
Jordi Barretina

Nature Communications

Published 16 October 2018

Crick labs

Peter Van Loo

Full details

Timing somatic events in the evolution of cancer

Authors (2)

Genome Biology

Published 24 July 2018

Crick labs

Peter Van Loo

Full details

Recurrent rearrangements of FOS and FOSB define osteoblastoma

Authors (22)

Matthew Fittall
William Mifsud
Nischalan Pillay
Hongtao Ye
Anna-Christina Strobl
Annelien Verfaillie
[...]
Peter Van Loo
Cristina R Antonescu
Peter J Campbell
Adrienne M Flanagan
Sam Behjati

Nature Communications

Published 1 June 2018

Crick labs

Peter Van Loo

Full details

Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets

Authors (88)

David C Wedge
Gunes Gundem
Thomas Mitchell
Dan J Woodcock
Inigo Martincorena
Mohammed Ghori
[...]
Christopher S Foster
Daniel S Brewer
David E Neal
Colin S Cooper
Rosalind A Eeles

Nature Genetics

Published 1 May 2018

Crick labs

Peter Van Loo

Full details

Deterministic evolutionary trajectories influence primary tumor growth: TRACERx Renal

Authors (71)

Samra Turajlic
Hang Xu
Kevin Litchfield
Andrew Rowan
Stuart Horswell
Tim Chambers
[...]
Peter Van Loo
Peter Campbell
James Larkin
Charles Swanton
TRACERx Renal Consortium

Cell

Published 19 April 2018

Crick labs/ facilities

Full details

How subclonal modeling is changing the metastatic paradigm

Authors (6)

Geoff Macintyre
Peter Van Loo
Niall M Corcoran
David C Wedge
Florian Markowetz
Christopher M Hovens

Clinical cancer research

Published 18 November 2017

Crick labs

Peter Van Loo

Full details

Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors

Authors (18)

Jiqiu Cheng
Jonas Demeulemeester
David C Wedge
Hans Kristian Vollan
Jason J Pitt
Hege G Russnes
[...]
Vessela N Kristensen
Michael R Stratton
Ole Christian Lingjærde
Yves Moreau
Peter Van Loo

Nature Communications

Published 31 October 2017

Crick labs

Peter Van Loo

Full details

Allele-specific HLA loss and immune escape in lung cancer evolution

Authors (12)

Nicholas McGranahan
Rachel Rosenthal
Crispin T Hiley
Andrew Rowan
Thomas BK Watkins
Gareth A Wilson
[...]
Selvaraju Veeriah
Peter Van Loo
Javier Herrero
Charles Swanton
TRACERx Consortium

Cell

Published 30 November 2017

Crick labs

Full details

Universal patterns of selection in cancer and somatic tissues

Authors (9)

Iñigo Martincorena
Keiran M Raine
Moritz Gerstung
Kevin J Dawson
Kerstin Haase
Peter Van Loo
Helen Davies
Michael R Stratton
Peter J Campbell

Cell

Published 14 June 2018

Crick labs

Peter Van Loo

Full details

Appraising the relevance of DNA copy number loss and gain in prostate cancer using whole genome DNA sequence data

Authors (57)

Niedzica Camacho
Peter Van Loo
Sandra Edwards
Jonathan D Kay
Lucy Matthews
Kerstin Haase
[...]
Ultan McDermott
David E Neal
Rosalind Eeles
Colin S Cooper
Daniel S Brewer

PLOS Genetics

Published 25 September 2017

Crick labs

Peter Van Loo

Full details

Genomic evolution of breast cancer metastasis and relapse

Authors (30)

Lucy R Yates
Stian Knappskog
David Wedge
James HR Farmery
Santiago Gonzalez
Inigo Martincorena
[...]
John W Martens
Andrea L Richardson
Andrew Tutt
Per Eystein Lønning
Peter J Campbell

Cancer Cell

Published 14 August 2017

Crick labs

Peter Van Loo

Full details

Intratumoural evolutionary landscape of high-risk prostate cancer: the PROGENY study of genomic and immune parameters

Authors (34)

M Linch
G Goh
Crispin Hiley
Y Shanmugabavan
N McGranahan
Andrew Rowan
[...]
SA Quezada
T Marafioti
M Gerlinger
HU Ahmed
Charles Swanton

Annals of Oncology

Published 1 October 2017

Crick labs/ facilities

Full details

Recurrent mutation of IGF signalling genes and distinct patterns of genomic rearrangement in osteosarcoma

Authors (33)

Sam Behjati
Patrick S Tarpey
Kerstin Haase
Hongtao Ye
Matthew D Young
Ludmil B Alexandrov
[...]
Roberto Tirabosco
Peter Van Loo
Michael R Stratton
Adrienne M Flanagan
Peter J Campbell

Nature Communications

Published 23 June 2017

Crick labs

Peter Van Loo

Full details

Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution

Authors (105)

Christopher Abbosh
Nicolai Birkbak
Gareth Wilson
Mariam Jamal-Hanjani
Tudor Constantin
Raheleh Salari
[...]
Jacqui A Shaw
Bernhard G Zimmermann
The TRACERx Consortium
The PEACE Consortium
Charles Swanton

Nature

Published 25 May 2017

Crick labs/ facilities

Full details

Tracking the evolution of non-small-cell lung cancer

Authors (84)

Mariam Jamal-Hanjani
Gareth A Wilson
Nicholas McGranahan
Nicolai Birkbak
Tom Watkins
Selvaraju Veeriah
[...]
Peter Van Loo
Caroline Dive
Allan Hackshaw
Charles Swanton
The TRACERx Consortium

New England Journal of Medicine

Published 26 April 2017

Crick labs/ facilities

Full details

Principles of reconstructing the subclonal architecture of cancers

Authors (3)

Stefan C Dentro
David C Wedge
Peter Van Loo

Cold Spring Harbor Perspectives in Medicine

Published 7 March 2017

Crick labs

Peter Van Loo

Full details

Tracing the origin of disseminated tumor cells in breast cancer using single-cell sequencing

Authors (20)

Jonas Demeulemeester
Parveen Kumar
Elen K Møller
Silje Nord
David C Wedge
April Peterson
[...]
Kevin P White
Vessela N Kristensen
Peter Van Loo
Thierry Voet
Bjørn Naume

Genome Biology

Published 9 December 2016

Crick labs

Peter Van Loo

Full details

ascatNgs: identifying somatically acquired copy-number alterations from whole-genome sequencing data

Authors (10)

Keiran M Raine
Peter Van Loo
David C Wedge
David Jones
Andrew Menzies
Adam P Butler
Jon W Teague
Patrick Tarpey
Serena Nik-Zainal
Peter J Campbell

Current Protocols in Bioinformatics

Published 8 December 2016

Crick labs

Peter Van Loo

Full details

Mutational signatures associated with tobacco smoking in human cancer

Authors (14)

Ludmil B Alexandrov
Young Seok Ju
Kerstin Haase
Peter Van Loo
Inigo Martincorena
Serena Nik-Zainal
[...]
Tatsuhiro Shibata
Peter J Campbell
Paolo Vineis
David H Phillips
Michael R Stratton

Science

Published 4 November 2016

Crick labs

Peter Van Loo

Full details

Mutational signatures of ionizing radiation in second malignancies

Authors (34)

Sam Behjati
Gunes Gundem
David C Wedge
Nicola D Roberts
Patrick S Tarpey
Susanna L Cooke
[...]
Andrea L Richardson
Adrienne M Flanagan
Michael R Stratton
Peter J Campbell
ICGC Prostate Group

Nature Communications

Published 12 September 2016

Crick labs

Peter Van Loo

Full details

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Characterization of Nigerian breast cancer reveals prevalent homologous recombination deficiency and aggressive molecular features

Timing somatic events in the evolution of cancer

Recurrent rearrangements of FOS and FOSB define osteoblastoma

Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets

Deterministic evolutionary trajectories influence primary tumor growth: TRACERx Renal

How subclonal modeling is changing the metastatic paradigm

Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors

Allele-specific HLA loss and immune escape in lung cancer evolution

Universal patterns of selection in cancer and somatic tissues

Appraising the relevance of DNA copy number loss and gain in prostate cancer using whole genome DNA sequence data

Genomic evolution of breast cancer metastasis and relapse

Intratumoural evolutionary landscape of high-risk prostate cancer: the PROGENY study of genomic and immune parameters

Recurrent mutation of IGF signalling genes and distinct patterns of genomic rearrangement in osteosarcoma

Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution

Tracking the evolution of non-small-cell lung cancer

Principles of reconstructing the subclonal architecture of cancers

Tracing the origin of disseminated tumor cells in breast cancer using single-cell sequencing

ascatNgs: identifying somatically acquired copy-number alterations from whole-genome sequencing data

Mutational signatures associated with tobacco smoking in human cancer

Mutational signatures of ionizing radiation in second malignancies

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Postdoctoral clinical fellows

Hello Brain!

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Year published

Research topics

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