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Breadcrumb Rickie Patani Patani lab Human Stem Cells and Neurodegeneration Laboratory : Publications Lab contentLab contentIn this section Overview Vacancies Lab news Publications Members Human stem cell derived spinal motor neurons (left) and astrocytes (right). Credit: Dr Giulia Tyzack (Patani Lab). Toggle to view hero caption PublicationsYear published2023 (2)2018 (1)2017 (1) Facet Year publishedResearch topicsCell Biology (4)Neurosciences (4)Stem Cells (4)Biochemistry & Proteomics (2)Computational & Systems Biology (2)Gene Expression (2)Genetics & Genomics (2)Tumour Biology (2)Cell Cycle & Chromosomes (1)Chemical Biology & High Throughput (1)Genome Integrity & Repair (1)Model Organisms (1) Facet Research topicsPublication typeJournal article (4) (-)Primary research (4) Facet Publication typeJournal (-)Nature Communications (4) Facet Journal Publications Displaying 1 - 4 of 4Last updated : 24 April 2024 03:48 The ALS/FTD-related C9orf72 hexanucleotide repeat expansion forms RNA condensates through multimolecular G-quadruplexes Authors (16) Federica RaguseoYiran Wang Jessica LiMarija Petric Howe Rubika Balendra Anouk Huyghebaert[...] Francesco A Aprile Yuval ElaniRickie Patani Lorenzo Di MicheleMarco di Antonio Nature Communications Published 13 December 2023 Crick labs/ facilitiesRickie PataniMarco Di AntonioHigh Throughput ScreeningFlow CytometryFull details Integrated transcriptome landscape of ALS identifies genome instability linked to TDP-43 pathology Authors (14)Oliver ZiffJacob NeevesJamie MitchellGiulia Tyzack Carlos Martinez-Ruiz Raphaelle Luisier[...]Simon Boulton Ammar Al-ChalabiGavin Kelly Jack HumphreyRickie Patani Nature Communications Published 20 April 2023 Crick labs/ facilitiesJernej UleRickie PataniSimon BoultonBioinformatics and BiostatisticsScientific computingFull details Intron retention and nuclear loss of SFPQ are molecular hallmarks of ALS Authors (13) Raphaelle LuisierGiulia Tyzack Claire E HallJamie MitchellHelen DevineDoaa Taha[...] Linda Greensmith Jia NewcombeJernej UleNicholas LuscombeRickie Patani Nature Communications Published 22 May 2018 Crick labsJernej UleRickie PataniNicholas LuscombeFull details A neuroprotective astrocyte state is induced by neuronal signal EphB1 but fails in ALS models Authors (13)Giulia Tyzack Claire E Hall Christopher R Sibley Tomasz Cymes Serhiy Forostyak Giulia Carlino[...] Su-Chun Zhang George M Gibbons Jia NewcombeRickie Patani András Lakatos Nature Communications Published 27 October 2017 Crick labsRickie PataniFull details Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
The ALS/FTD-related C9orf72 hexanucleotide repeat expansion forms RNA condensates through multimolecular G-quadruplexes Authors (16) Federica RaguseoYiran Wang Jessica LiMarija Petric Howe Rubika Balendra Anouk Huyghebaert[...] Francesco A Aprile Yuval ElaniRickie Patani Lorenzo Di MicheleMarco di Antonio Nature Communications Published 13 December 2023 Crick labs/ facilitiesRickie PataniMarco Di AntonioHigh Throughput ScreeningFlow CytometryFull details
Integrated transcriptome landscape of ALS identifies genome instability linked to TDP-43 pathology Authors (14)Oliver ZiffJacob NeevesJamie MitchellGiulia Tyzack Carlos Martinez-Ruiz Raphaelle Luisier[...]Simon Boulton Ammar Al-ChalabiGavin Kelly Jack HumphreyRickie Patani Nature Communications Published 20 April 2023 Crick labs/ facilitiesJernej UleRickie PataniSimon BoultonBioinformatics and BiostatisticsScientific computingFull details
Intron retention and nuclear loss of SFPQ are molecular hallmarks of ALS Authors (13) Raphaelle LuisierGiulia Tyzack Claire E HallJamie MitchellHelen DevineDoaa Taha[...] Linda Greensmith Jia NewcombeJernej UleNicholas LuscombeRickie Patani Nature Communications Published 22 May 2018 Crick labsJernej UleRickie PataniNicholas LuscombeFull details
A neuroprotective astrocyte state is induced by neuronal signal EphB1 but fails in ALS models Authors (13)Giulia Tyzack Claire E Hall Christopher R Sibley Tomasz Cymes Serhiy Forostyak Giulia Carlino[...] Su-Chun Zhang George M Gibbons Jia NewcombeRickie Patani András Lakatos Nature Communications Published 27 October 2017 Crick labsRickie PataniFull details