Research case studies Explore a selection of reports that spotlight particular areas of research at the Crick over the past five years.
Postdoctoral clinical fellows Opportunities for postdoctoral clinicians to consolidate their research experience.
Breadcrumb Robert J Wilkinson Wilkinson lab Tuberculosis Laboratory : Publications Lab contentLab contentIn this section Overview Areas of interest Publications Members Vacancies News Khayelitsha, South Africa: a peri-urban township of around 400000 people 30 km from the centre of Cape Town. In Khayelitsha the chances of developing tuberculosis in any year are around 1%, much higher if a person is HIV-coinfected. Toggle to view hero caption PublicationsYear published (-)2011 (11) Facet Year publishedPublication typeJournal article (11)Primary research (9)Review (2) Facet Publication typeJournalPLOS ONE (3)European Journal of Immunology (2)Lancet (2)Drug Discovery Today (1)Proceedings of the National Academy of Sciences of the United States of America (1)Thorax (1)Tuberculosis (1) Facet Journal Publications Displaying 1 - 11 of 11Last updated : 29 March 2024 02:11 Reciprocal seasonal variation in vitamin D status and tuberculosis notifications in Cape Town, South Africa Authors (14) Adrian R Martineau Shepherd Nhamoyebonde Tolu Oni Molebogeng X Rangaka Suzaan Marais Nonzwakazi Bangani[...] Judy Caldwell Timothy R Venton Peter M TimmsKatalin WilkinsonRobert Wilkinson Proceedings of the National Academy of Sciences of the United States of America Published 24 October 2011 Crick labsRobert J WilkinsonFull details HIV-1 infection alters CD4+ memory T cell phenotype at the site of disease in extrapulmonary tuberculosis Authors (11) K Matthews M Ntsekhe F Syed T Scriba J Russell K Tibazarwa A Deffur W Hanekom BM MayosiRobert WilkinsonKatalin Wilkinson European Journal of Immunology Published 5 October 2011 Crick labsRobert J WilkinsonFull details Predominance of interleukin-22 over interleukin-17 at the site of disease in human tuberculosis Authors (16) K MatthewsKatalin Wilkinson B Kalsdorf T Roberts A Diacon G Walzl[...] R Dawson K DhedaRobert Wilkinson WA Hanekom TJ Scriba Tuberculosis Published 16 July 2011 Crick labsRobert J WilkinsonFull details High prevalence of subclinical tuberculosis in HIV-1-infected persons without advanced immunodeficiency: implications for TB screening Authors (10) T Oni R Burke R Tsekela N Bangani R Seldon HP Gideon K WoodKatalin Wilkinson THM OttenhoffRobert Wilkinson Thorax Published 31 May 2011 Crick labsRobert J WilkinsonFull details Barriers to initiation of antiretrovirals during antituberculosis therapy in Africa Authors (6) DJ Pepper S MaraisRobert Wilkinson F Bhaijee V De Azevedo G Meintjes PLOS ONE Published 1 May 2011 Crick labsRobert J WilkinsonFull details Isoniazid preventive therapy in HIV infection Authors (2) LE DoddRobert Wilkinson Lancet Published 1 May 2011 Crick labsRobert J WilkinsonFull details Programmed Death Ligand 1 is over-expressed by neutrophils in the blood of patients with active tuberculosis Authors (11) FW McNab MPR BerryChristine Graham SAA Bloch T OniKatalin WilkinsonRobert Wilkinson OM Kon J Banchereau D ChaussabelAnne O'Garra European Journal of Immunology Published 20 April 2011 Crick labsRobert J WilkinsonAnne O’GarraFull details High-dose vitamin D3 during intensive-phase antimicrobial treatment of pulmonary tuberculosis: a double-blind randomised controlled trial Authors (26) AR Martineau PM Timms GH Bothamley Y Hanifa K Islam AP Claxton[...]Robert Wilkinson V Nikolayevskyy FA Drobniewski SM Eldridge CJ Griffiths Lancet Published 15 January 2011 Crick labsRobert J WilkinsonFull details Immune responses to the Enduring Hypoxic Response antigen Rv0188 are preferentially detected in Mycobacterium bovis infected cattle with low pathology Authors (8) Gareth J Jones Chris Pirson Hannah P GideonKatalin Wilkinson David R ShermanRobert Wilkinson R Glyn Hewinson H Martin Vordermeier PLOS ONE Published 1 January 2011 Crick labsRobert J WilkinsonFull details Presentation and outcome of tuberculous meningitis in a high HIV prevalence setting Authors (5) S Marais DJ Pepper C SchutzRobert Wilkinson G Meintjes PLOS ONE Published 1 January 2011 Crick labsRobert J WilkinsonFull details Understanding latent tuberculosis: the key to improved diagnostic and novel treatment strategies Authors (3) H Esmail CE BarryRobert Wilkinson Drug Discovery Today Published 1 January 2011 Crick labsRobert J WilkinsonFull details Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Reciprocal seasonal variation in vitamin D status and tuberculosis notifications in Cape Town, South Africa Authors (14) Adrian R Martineau Shepherd Nhamoyebonde Tolu Oni Molebogeng X Rangaka Suzaan Marais Nonzwakazi Bangani[...] Judy Caldwell Timothy R Venton Peter M TimmsKatalin WilkinsonRobert Wilkinson Proceedings of the National Academy of Sciences of the United States of America Published 24 October 2011 Crick labsRobert J WilkinsonFull details
HIV-1 infection alters CD4+ memory T cell phenotype at the site of disease in extrapulmonary tuberculosis Authors (11) K Matthews M Ntsekhe F Syed T Scriba J Russell K Tibazarwa A Deffur W Hanekom BM MayosiRobert WilkinsonKatalin Wilkinson European Journal of Immunology Published 5 October 2011 Crick labsRobert J WilkinsonFull details
Predominance of interleukin-22 over interleukin-17 at the site of disease in human tuberculosis Authors (16) K MatthewsKatalin Wilkinson B Kalsdorf T Roberts A Diacon G Walzl[...] R Dawson K DhedaRobert Wilkinson WA Hanekom TJ Scriba Tuberculosis Published 16 July 2011 Crick labsRobert J WilkinsonFull details
High prevalence of subclinical tuberculosis in HIV-1-infected persons without advanced immunodeficiency: implications for TB screening Authors (10) T Oni R Burke R Tsekela N Bangani R Seldon HP Gideon K WoodKatalin Wilkinson THM OttenhoffRobert Wilkinson Thorax Published 31 May 2011 Crick labsRobert J WilkinsonFull details
Barriers to initiation of antiretrovirals during antituberculosis therapy in Africa Authors (6) DJ Pepper S MaraisRobert Wilkinson F Bhaijee V De Azevedo G Meintjes PLOS ONE Published 1 May 2011 Crick labsRobert J WilkinsonFull details
Isoniazid preventive therapy in HIV infection Authors (2) LE DoddRobert Wilkinson Lancet Published 1 May 2011 Crick labsRobert J WilkinsonFull details
Programmed Death Ligand 1 is over-expressed by neutrophils in the blood of patients with active tuberculosis Authors (11) FW McNab MPR BerryChristine Graham SAA Bloch T OniKatalin WilkinsonRobert Wilkinson OM Kon J Banchereau D ChaussabelAnne O'Garra European Journal of Immunology Published 20 April 2011 Crick labsRobert J WilkinsonAnne O’GarraFull details
High-dose vitamin D3 during intensive-phase antimicrobial treatment of pulmonary tuberculosis: a double-blind randomised controlled trial Authors (26) AR Martineau PM Timms GH Bothamley Y Hanifa K Islam AP Claxton[...]Robert Wilkinson V Nikolayevskyy FA Drobniewski SM Eldridge CJ Griffiths Lancet Published 15 January 2011 Crick labsRobert J WilkinsonFull details
Immune responses to the Enduring Hypoxic Response antigen Rv0188 are preferentially detected in Mycobacterium bovis infected cattle with low pathology Authors (8) Gareth J Jones Chris Pirson Hannah P GideonKatalin Wilkinson David R ShermanRobert Wilkinson R Glyn Hewinson H Martin Vordermeier PLOS ONE Published 1 January 2011 Crick labsRobert J WilkinsonFull details
Presentation and outcome of tuberculous meningitis in a high HIV prevalence setting Authors (5) S Marais DJ Pepper C SchutzRobert Wilkinson G Meintjes PLOS ONE Published 1 January 2011 Crick labsRobert J WilkinsonFull details
Understanding latent tuberculosis: the key to improved diagnostic and novel treatment strategies Authors (3) H Esmail CE BarryRobert Wilkinson Drug Discovery Today Published 1 January 2011 Crick labsRobert J WilkinsonFull details