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Breadcrumb Robert J Wilkinson Wilkinson lab Tuberculosis Laboratory : Publications Lab contentLab contentIn this section Overview Areas of interest Publications Members Vacancies News Khayelitsha, South Africa: a peri-urban township of around 400000 people 30 km from the centre of Cape Town. In Khayelitsha the chances of developing tuberculosis in any year are around 1%, much higher if a person is HIV-coinfected. Toggle to view hero caption PublicationsYear published (-)2017 (22) Facet Year publishedResearch topicsHuman Biology & Physiology (22)Immunology (22)Infectious Disease (22)Model Organisms (22)Cell Biology (1)Computational & Systems Biology (1) Facet Research topicsPublication typeJournal article (22)Primary research (17)Review (3)Commentary (1)Method (1) Facet Publication typeJournalClinical Infectious Diseases (4)Frontiers in Immunology (3)Journal of Infectious Diseases (2)Annals of the American Thoracic Society (1)Cell Host & Microbe (1)European Journal of Immunology (1)European Respiratory Journal (1)Experimental and Molecular Pathology (1)Gates Open Research (1)International Journal of Cardiology Heart & Vasculature (1)Journal of Acquired Immune Deficiency Syndromes (1)Journal of Clinical Microbiology (1)Journal of Immunology (1)Molecular Biology and Evolution (1)Nature Reviews Neurology (1)Open Forum Infectious Diseases (1) Facet Journal Publications Displaying 1 - 20 of 22Last updated : 20 April 2024 03:29 Aiming at the global elimination of viral hepatitis: Challenges along the care continuum Authors (16) Alastair Heffernan Ella Barber Nicola A Cook Asmaa I Gomaa Yolande X Harley Christopher R Jones[...] Mark W Sonderup C Wendy Spearman Imam WakedRobert Wilkinson Simon D Taylor-Robinson Open Forum Infectious Diseases Published 1 January 2018 Crick labsRobert J WilkinsonFull details Using biomarkers to predict TB treatment duration (Predict TB): a prospective, randomized, noninferiority, treatment shortening clinical trial Authors (36) Ray Y Chen Laura E Via Lori E Dodd Gerhard Walzl Stephanus T Malherbe André G Loxton[...] Kriti Arora Bronwyn Smith Jill Winter Clifton E Barry Predict TB Study Group Gates Open Research Published 6 November 2017 Crick labsRobert J WilkinsonFull details Effect of prednisolone on inflammatory markers in pericardial tuberculosis: A pilot study Authors (7) J ShenjeRachel Lai IL Ross BM MayosiRobert Wilkinson M NtsekheKatalin Wilkinson International Journal of Cardiology Heart & Vasculature Published 1 March 2018 Crick labsRobert J WilkinsonFull details Effect of HIV on the frequency and number of Mycobacterium tuberculosis-specific CD4+ T cells in blood and the airways during latent M. tuberculosis infection Authors (15) Rubina Bunjun Catherine Riou Andreia P Soares Narjis Thawer Tracey L Müller Agano Kiravu[...] Florian von Groote-Bidlingmaier Willem Hanekom Gerhard WalzlRobert Wilkinson Wendy A Burgers Journal of Infectious Diseases Published 15 December 2017 Crick labsRobert J WilkinsonFull details TBVAC2020: Advancing tuberculosis vaccines from discovery to clinical development Authors (17) Stefan HE Kaufmann Hazel M Dockrell Nick Drager Mei Mei Ho Helen McShane Olivier Neyrolles[...] Frank AW Verreck Ann Williams TBVAC2020 ConsortiumKatalin WilkinsonRobert Wilkinson Frontiers in Immunology Published 4 October 2017 Crick labsRobert J WilkinsonFull details Tuberculous meningitis Authors (12)Robert Wilkinson Ursula Rohlwink Usha Kant Misra Reinout van Crevel Nguyen Thi Hoang Mai Kelly E Dooley[...] Anthony Figaji Rada Savic Regan Solomons Guy E Thwaites Tuberculous Meningitis International Research Consortium Nature Reviews Neurology Published 8 September 2017 Crick labsRobert J WilkinsonFull details Analysis of the phenotype of Mycobacterium tuberculosis-specific CD4+ T cells to discriminate latent from active tuberculosis in HIV-uninfected and HIV-infected individuals Authors (5) C Riou N Berkowitz R Goliath WA BurgersRobert Wilkinson Frontiers in Immunology Published 10 August 2017 Crick labsRobert J WilkinsonFull details Characterization of Mycobacterium tuberculosis-specific cells using MHC class II tetramers reveals phenotypic differences related to HIV infection and tuberculosis disease Authors (8) Natalie Strickland Tracey L Müller Natacha Berkowitz Rene Goliath Mary N CarringtonRobert Wilkinson Wendy A Burgers Catherine Riou Journal of Immunology Published 1 October 2017 Crick labsRobert J WilkinsonFull details Low frequency of acquired isoniazid and rifampicin resistance in rifampicin-susceptible pulmonary tuberculosis in a setting of high HIV-1 infection and tuberculosis coprevalence Authors (6) Neesha Rockwood Frederick Sirgel Elizabeth Streicher Robin Warren Graeme MeintjesRobert Wilkinson Journal of Infectious Diseases Published 15 September 2017 Crick labsRobert J WilkinsonFull details Trilateral overlap of tuberculosis, diabetes and HIV-1 in a high-burden African setting: implications for TB control Authors (6) Tolu Oni Natacha Berkowitz Mmamapudi Kubjane Rene Goliath Naomi S LevittRobert Wilkinson European Respiratory Journal Published 1 July 2017 Crick labsRobert J WilkinsonFull details Biomarkers of cerebral injury and inflammation in pediatric tuberculous meningitis Authors (7) Ursula K Rohlwink Katya MauffKatalin Wilkinson Nico Enslin Emmanuel WegoyeRobert Wilkinson Anthony A Figaji Clinical Infectious Diseases Published 15 October 2017 Crick labsRobert J WilkinsonFull details Mycobacterium tuberculosis induction of heme oxygenase-1 expression is dependent on oxidative stress and reflects treatment outcomes Authors (15) Neesha Rockwood Diego L Costa Eduardo P Amaral Elsa Du Bruyn Andre Kubler Leonardo Gil-Santana[...]Katalin Wilkinson William R Bishai Alan SherRobert Wilkinson Bruno B Andrade Frontiers in Immunology Published 12 May 2017 Crick labsRobert J WilkinsonFull details A Rab20-dependent membrane trafficking pathway controls M. tuberculosis replication by regulating phagosome spaciousness and integrity Authors (9) Laura Schnettger Angela Rodgers Urska RepnikRachel Lai Gang Pei Martijn VerdoesRobert Wilkinson Douglas B YoungMaximiliano Gutierrez Cell Host & Microbe Published 10 May 2017 Crick labs/ facilitiesRobert J WilkinsonMaximiliano GutierrezLight MicroscopyBiological Research FacilityFull details Matrix degradation in human immunodeficiency virus type 1-associated tuberculosis and tuberculosis immune reconstitution inflammatory syndrome: a prospective observational study Authors (12) Naomi F WalkerKatalin Wilkinson Graeme Meintjes Liku B Tezera Rene Goliath Janique M Peyper[...] Charles Opondo Anna K CoussensRobert Wilkinson Jon S Friedland Paul T Elkington Clinical Infectious Diseases Published 1 July 2017 Crick labsRobert J WilkinsonFull details Minimizing tuberculosis risk in patients receiving anti-TNF therapy Authors (2) Hanif EsmailRobert Wilkinson Annals of the American Thoracic Society Published 1 May 2017 Crick labsRobert J WilkinsonFull details Mortality in severe human immunodeficiency virus-tuberculosis associates with innate immune activation and dysfunction of monocytes Authors (14) Saskia Janssen Charlotte Schutz Amy Ward Elisa NemesKatalin Wilkinson James Scriven[...] Rosie BurtonRobert Wilkinson Martin P Grobusch Tom Van der Poll Graeme Meintjes Clinical Infectious Diseases Published 1 July 2017 Crick labsRobert J WilkinsonFull details The CSF immune response in HIV-1-associated cryptococcal meningitis: macrophage activation, correlates of disease severity and effect of antiretroviral therapy Authors (10) James E Scriven Lisa M Graham Charlotte Schutz Thomas J ScribaKatalin WilkinsonRobert Wilkinson David R Boulware Britta C Urban Graeme Meintjes David G Lalloo Journal of Acquired Immune Deficiency Syndromes Published 1 July 2017 Crick labsRobert J WilkinsonFull details The influence of HIV on the evolution of Mycobacterium tuberculosis Authors (15) Anastasia S Koch Daniela Brites David StuckiJoanna Evans Ronnett Seldon Alexa Heekes[...] Valerie Mizrahi Julian Parkhill Sebastien Gagneux Darren P MartinRobert Wilkinson Molecular Biology and Evolution Published 1 July 2017 Crick labsRobert J WilkinsonFull details Utility of second-generation line probe assay (Hain MTBDRplus) directly on 2-month sputum specimens for monitoring tuberculosis treatment response Authors (6) Neesha Rockwood Justyna Wojno Yonas Ghebrekristos Mark P Nicol Graeme MeintjesRobert Wilkinson Journal of Clinical Microbiology Published 1 May 2017 Crick labsRobert J WilkinsonFull details Concentration-dependent antagonism and culture conversion in pulmonary tuberculosis Authors (9) Neesha Rockwood Jotam G Pasipanodya Paolo Denti Frederick Sirgel Maia Lesosky Tawanda Gumbo Graeme Meintjes Helen McIlleronRobert Wilkinson Clinical Infectious Diseases Published 15 May 2017 Crick labsRobert J WilkinsonFull details Pagination Current page 1 Page 2 Next page Next Last page Last Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Aiming at the global elimination of viral hepatitis: Challenges along the care continuum Authors (16) Alastair Heffernan Ella Barber Nicola A Cook Asmaa I Gomaa Yolande X Harley Christopher R Jones[...] Mark W Sonderup C Wendy Spearman Imam WakedRobert Wilkinson Simon D Taylor-Robinson Open Forum Infectious Diseases Published 1 January 2018 Crick labsRobert J WilkinsonFull details
Using biomarkers to predict TB treatment duration (Predict TB): a prospective, randomized, noninferiority, treatment shortening clinical trial Authors (36) Ray Y Chen Laura E Via Lori E Dodd Gerhard Walzl Stephanus T Malherbe André G Loxton[...] Kriti Arora Bronwyn Smith Jill Winter Clifton E Barry Predict TB Study Group Gates Open Research Published 6 November 2017 Crick labsRobert J WilkinsonFull details
Effect of prednisolone on inflammatory markers in pericardial tuberculosis: A pilot study Authors (7) J ShenjeRachel Lai IL Ross BM MayosiRobert Wilkinson M NtsekheKatalin Wilkinson International Journal of Cardiology Heart & Vasculature Published 1 March 2018 Crick labsRobert J WilkinsonFull details
Effect of HIV on the frequency and number of Mycobacterium tuberculosis-specific CD4+ T cells in blood and the airways during latent M. tuberculosis infection Authors (15) Rubina Bunjun Catherine Riou Andreia P Soares Narjis Thawer Tracey L Müller Agano Kiravu[...] Florian von Groote-Bidlingmaier Willem Hanekom Gerhard WalzlRobert Wilkinson Wendy A Burgers Journal of Infectious Diseases Published 15 December 2017 Crick labsRobert J WilkinsonFull details
TBVAC2020: Advancing tuberculosis vaccines from discovery to clinical development Authors (17) Stefan HE Kaufmann Hazel M Dockrell Nick Drager Mei Mei Ho Helen McShane Olivier Neyrolles[...] Frank AW Verreck Ann Williams TBVAC2020 ConsortiumKatalin WilkinsonRobert Wilkinson Frontiers in Immunology Published 4 October 2017 Crick labsRobert J WilkinsonFull details
Tuberculous meningitis Authors (12)Robert Wilkinson Ursula Rohlwink Usha Kant Misra Reinout van Crevel Nguyen Thi Hoang Mai Kelly E Dooley[...] Anthony Figaji Rada Savic Regan Solomons Guy E Thwaites Tuberculous Meningitis International Research Consortium Nature Reviews Neurology Published 8 September 2017 Crick labsRobert J WilkinsonFull details
Analysis of the phenotype of Mycobacterium tuberculosis-specific CD4+ T cells to discriminate latent from active tuberculosis in HIV-uninfected and HIV-infected individuals Authors (5) C Riou N Berkowitz R Goliath WA BurgersRobert Wilkinson Frontiers in Immunology Published 10 August 2017 Crick labsRobert J WilkinsonFull details
Characterization of Mycobacterium tuberculosis-specific cells using MHC class II tetramers reveals phenotypic differences related to HIV infection and tuberculosis disease Authors (8) Natalie Strickland Tracey L Müller Natacha Berkowitz Rene Goliath Mary N CarringtonRobert Wilkinson Wendy A Burgers Catherine Riou Journal of Immunology Published 1 October 2017 Crick labsRobert J WilkinsonFull details
Low frequency of acquired isoniazid and rifampicin resistance in rifampicin-susceptible pulmonary tuberculosis in a setting of high HIV-1 infection and tuberculosis coprevalence Authors (6) Neesha Rockwood Frederick Sirgel Elizabeth Streicher Robin Warren Graeme MeintjesRobert Wilkinson Journal of Infectious Diseases Published 15 September 2017 Crick labsRobert J WilkinsonFull details
Trilateral overlap of tuberculosis, diabetes and HIV-1 in a high-burden African setting: implications for TB control Authors (6) Tolu Oni Natacha Berkowitz Mmamapudi Kubjane Rene Goliath Naomi S LevittRobert Wilkinson European Respiratory Journal Published 1 July 2017 Crick labsRobert J WilkinsonFull details
Biomarkers of cerebral injury and inflammation in pediatric tuberculous meningitis Authors (7) Ursula K Rohlwink Katya MauffKatalin Wilkinson Nico Enslin Emmanuel WegoyeRobert Wilkinson Anthony A Figaji Clinical Infectious Diseases Published 15 October 2017 Crick labsRobert J WilkinsonFull details
Mycobacterium tuberculosis induction of heme oxygenase-1 expression is dependent on oxidative stress and reflects treatment outcomes Authors (15) Neesha Rockwood Diego L Costa Eduardo P Amaral Elsa Du Bruyn Andre Kubler Leonardo Gil-Santana[...]Katalin Wilkinson William R Bishai Alan SherRobert Wilkinson Bruno B Andrade Frontiers in Immunology Published 12 May 2017 Crick labsRobert J WilkinsonFull details
A Rab20-dependent membrane trafficking pathway controls M. tuberculosis replication by regulating phagosome spaciousness and integrity Authors (9) Laura Schnettger Angela Rodgers Urska RepnikRachel Lai Gang Pei Martijn VerdoesRobert Wilkinson Douglas B YoungMaximiliano Gutierrez Cell Host & Microbe Published 10 May 2017 Crick labs/ facilitiesRobert J WilkinsonMaximiliano GutierrezLight MicroscopyBiological Research FacilityFull details
Matrix degradation in human immunodeficiency virus type 1-associated tuberculosis and tuberculosis immune reconstitution inflammatory syndrome: a prospective observational study Authors (12) Naomi F WalkerKatalin Wilkinson Graeme Meintjes Liku B Tezera Rene Goliath Janique M Peyper[...] Charles Opondo Anna K CoussensRobert Wilkinson Jon S Friedland Paul T Elkington Clinical Infectious Diseases Published 1 July 2017 Crick labsRobert J WilkinsonFull details
Minimizing tuberculosis risk in patients receiving anti-TNF therapy Authors (2) Hanif EsmailRobert Wilkinson Annals of the American Thoracic Society Published 1 May 2017 Crick labsRobert J WilkinsonFull details
Mortality in severe human immunodeficiency virus-tuberculosis associates with innate immune activation and dysfunction of monocytes Authors (14) Saskia Janssen Charlotte Schutz Amy Ward Elisa NemesKatalin Wilkinson James Scriven[...] Rosie BurtonRobert Wilkinson Martin P Grobusch Tom Van der Poll Graeme Meintjes Clinical Infectious Diseases Published 1 July 2017 Crick labsRobert J WilkinsonFull details
The CSF immune response in HIV-1-associated cryptococcal meningitis: macrophage activation, correlates of disease severity and effect of antiretroviral therapy Authors (10) James E Scriven Lisa M Graham Charlotte Schutz Thomas J ScribaKatalin WilkinsonRobert Wilkinson David R Boulware Britta C Urban Graeme Meintjes David G Lalloo Journal of Acquired Immune Deficiency Syndromes Published 1 July 2017 Crick labsRobert J WilkinsonFull details
The influence of HIV on the evolution of Mycobacterium tuberculosis Authors (15) Anastasia S Koch Daniela Brites David StuckiJoanna Evans Ronnett Seldon Alexa Heekes[...] Valerie Mizrahi Julian Parkhill Sebastien Gagneux Darren P MartinRobert Wilkinson Molecular Biology and Evolution Published 1 July 2017 Crick labsRobert J WilkinsonFull details
Utility of second-generation line probe assay (Hain MTBDRplus) directly on 2-month sputum specimens for monitoring tuberculosis treatment response Authors (6) Neesha Rockwood Justyna Wojno Yonas Ghebrekristos Mark P Nicol Graeme MeintjesRobert Wilkinson Journal of Clinical Microbiology Published 1 May 2017 Crick labsRobert J WilkinsonFull details
Concentration-dependent antagonism and culture conversion in pulmonary tuberculosis Authors (9) Neesha Rockwood Jotam G Pasipanodya Paolo Denti Frederick Sirgel Maia Lesosky Tawanda Gumbo Graeme Meintjes Helen McIlleronRobert Wilkinson Clinical Infectious Diseases Published 15 May 2017 Crick labsRobert J WilkinsonFull details