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Coronavirus (COVID-19) research Crick researchers are working at the forefront of the scientific response to answer some of the most urgent questions about the SARS-CoV-2 pathogen, from how we can improve testing, to why it’s deadly in some people but causes no symptoms in others.
Sex-reversed male XY mouse (left) and female XX mouse (right). Read the news article to find out more. Nitzan Gonen, a postdoc in Robin Lovell-Badge's lab led the researcher, working in partnership with GeMS. Toggle to view hero caption Robin Lovell-Badge : Publications Lab MenuLab Menu Overview Areas of interest Publications Members Vacancies LAB NEWS Breadcrumb Research A Z of research labs Robin Lovell Badge PublicationsYear published2021 (13)2020 (8)2019 (5)2018 (3)2017 (6)2016 (6)2015 (6)2014 (6)2013 (8)2012 (11)2011 (8)2010 (7) Facet Year publishedResearch topicsDevelopmental Biology (47)Genetics & Genomics (47)Model Organisms (47)Neurosciences (47)Stem Cells (47)Tumour Biology (47)Computational & Systems Biology (3)Gene Expression (3)Genome Integrity & Repair (3)Chemical Biology & High Throughput (2)Cell Biology (1)Cell Cycle & Chromosomes (1)Human Biology & Physiology (1)Signalling & Oncogenes (1)Synthetic Biology (1) Facet Research topicsPublication typeJournal article (87)Primary research (51)Review (22)Commentary (9)Letter (2)Editorial (1)Method (1)Obituary (1) Facet Publication typeJournalDevelopment (6)Nature (5)PLOS ONE (5)Cell Stem Cell (4)Developmental Biology (3)Nature Biotechnology (3)Cancer Research (2)Developmental Cell (2)eLife (2)International Journal of Biochemistry & Cell Biology (2)Journal of Molecular Endocrinology (2)Methods in Molecular Biology (2)Nature Methods (2)PLOS Genetics (2)Proceedings of the National Academy of Sciences of the United States of America (2)Proceedings of the National Academy of Sciences of USA (2)Science (2)Sexual Development (2)Aging Cell (1)American Journal of Bioethics (1)Animal Technology and Welfare (1)Biology of Reproduction (1)Biology of Sex Differences (1)British Journal of Cancer (1)Cancers (1)Cell (1)Cell Metabolism (1)Chromosome Research (1)Current Topics in Developmental Biology (1)Endocrine Connections (1)Endocrinology (1)European Journal of Neuroscience (1)Expert opinion on therapeutic targets (1)FEBS Journal (1)Frontiers in Cellular Neuroscience (1)Frontiers in Endocrinology (1)Frontiers in Physiology (1)Genes and Development (1)Human Gene Therapy Methods (1)Journal of Cardiovascular Translational Research (1)Journal of Clinical Investigation (1)Journal of Neuroendocrinology (1)Laboratory Animals (1)Mechanisms of Development (1)Molecular and Cellular Endocrinology (1)Molecular Human Reproduction (1)Nature Neuroscience (1)New England Journal of Medicine (1)Oncogenesis (1)Proceedings of the National Academy of Sciences (1)Reproduction Fertility and Development (1)Scientific Reports (1)Stem Cell Reports (1)The CRISPR Journal (1)Trends in Endocrinology & Metabolism (1) Facet Journal Publications Displaying 1 - 20 of 87Last updated : 06 August 2021 02:09 ISSCR guidelines uphold human right to science for benefit of all Authors (3) Zubin MasterRobin Lovell-Badge Bartha Knoppers Nature Published 22 July 2021 Crick labsRobin Lovell-BadgeFull details New guidelines for stem cell and embryo research from the ISSCR Authors (3) Eric AnthonyRobin Lovell-Badge Sean J Morrison Cell Stem Cell Published 3 June 2021 Crick labsRobin Lovell-BadgeFull details ISSCR guidelines for stem cell research and clinical translation: The 2021 update Authors (47)Robin Lovell-Badge Eric Anthony Roger A Barker Tania Bubela Ali H Brivanlou Melissa Carpenter[...] Jun Takahashi Fuchou Tang Leigh Turner Patricia J Zettler Xiaomei Zhai Stem Cell Reports Published 8 June 2021 Crick labsKathy NiakanRobin Lovell-BadgeFull details Stem-cell guidelines: why it was time for an update Authors (1)Robin Lovell-Badge Nature Published 27 May 2021 Crick labsRobin Lovell-BadgeFull details Editorial: Plasticity in the vertebrate pituitary, including regulatory mechanisms Authors (3) Romain FontaineKarine Rizzoti Finn-Arne Weltzien Frontiers in Endocrinology Published 1 May 2021 Crick labsRobin Lovell-BadgeFull details Two alternative methods for the retrieval of somatic cell populations from the mouse ovary Authors (9)Emily Frost EA FordOzlem Gunes Taylor S Boeing EL Beckett SD RomanRobin Lovell-Badge EA Mclaughlin JM Sutherland Molecular Human Reproduction Published 10 May 2021 Crick labs/ facilitiesRobin Lovell-BadgeBioinformatics and BiostatisticsFull details Novel tools and investigative approaches for the study of oligodendrocyte precursor cells (NG2-Glia) in CNS development and disease Authors (3)Christophe GalichetRichard ClaytonRobin Lovell-Badge Frontiers in Cellular Neuroscience Published 1 April 2021 Crick labsRobin Lovell-BadgeFull details Establishing and maintaining fertility: the importance of cell cycle arrest Authors (5)Emily FrostOzlem Gunes Taylor Mark A BakerRobin Lovell-Badge Jessie M Sutherland Genes and Development Published 1 May 2021 Crick labsRobin Lovell-BadgeFull details CRISPR/Cas9 deletion of SOX2 regulatory region 2 (SRR2) decreases SOX2 malignant activity in glioblastoma Authors (7) A Saenz-Antoñanzas V Moncho-Amor J Auzmendi-Iriarte A Elua-PininKarine RizzotiRobin Lovell-Badge A Matheu Cancers Published 29 March 2021 Crick labsRobin Lovell-BadgeFull details Primary sex determination in birds depends on DMRT1 dosage, but gonadal sex does not determine adult secondary sex characteristics Authors (10) Jason IoannidisOzlem Gunes Taylor Debiao Zhao Long Liu Alewo Idoko-Akoh Daoqing GongRobin Lovell-BadgeSilvana Guioli Mike J McGrew Michael Clinton Proceedings of the National Academy of Sciences of USA Published 9 March 2021 Crick labsRobin Lovell-BadgeFull details Applications of genome editing on laboratory animals Authors (2)Christophe GalichetRobin Lovell-Badge Laboratory Animals Published 17 February 2021 Crick labsRobin Lovell-BadgeFull details SOX2 is required independently in both stem and differentiated cells for pituitary tumorigenesis in p27-null mice Authors (6)Veronica Moncho Amor Probir ChakravartyChristophe Galichet Ander MatheuRobin Lovell-BadgeKarine Rizzoti Proceedings of the National Academy of Sciences of USA Published 16 February 2021 Crick labs/ facilitiesRobin Lovell-BadgeBioinformatics and BiostatisticsLight MicroscopyFlow CytometryBiological Research FacilityAdvanced SequencingFull details Dentate gyrus development requires a cortical hem-derived astrocytic scaffold Authors (4)Alessia CaramelloChristophe GalichetKarine RizzotiRobin Lovell-Badge eLife Published 4 January 2021 Crick labs/ facilitiesRobin Lovell-BadgeLight MicroscopyExperimental HistopathologyBiological Research FacilityFull details Paul S. Burgoyne (1946-2020) Authors (4)James TurnerShantha Mahadevaiah Arthur P ArnoldRobin Lovell-Badge Development Published 27 October 2020 Crick labsJames TurnerRobin Lovell-BadgeFull details Going public with your research Authors (1)Ozlem Gunes Taylor The CRISPR Journal Published 24 August 2020 Crick labsRobin Lovell-BadgeFull details Signal transducer and activator of transcription (STAT) 1 and STAT3 are expressed in the human ovary and have Janus kinase 1-independent functions in the COV434 human granulosa cell line Authors (8)Emily Frost EA Ford AE Peters NL Reed EA McLaughlin MA BakerRobin Lovell-Badge JM Sutherland Reproduction Fertility and Development Published 1 August 2020 Crick labsRobin Lovell-BadgeFull details Testis formation in XX individuals resulting from novel pathogenic variants in Wilms’ tumor 1 (WT1) gene Authors (33) Caroline EozenouNitzan Gonen Maria Sol Touzon Anne Jorgensen Svetlana A Yatsenko Leila Fusee[...] Ken McElreavey Alicia BelgoroskyRobin Lovell-Badge Aleksandar Rajkovic Anu Bashamboo Proceedings of the National Academy of Sciences Published 16 June 2020 Crick labs/ facilitiesRobin Lovell-BadgeExperimental HistopathologyBiological Research FacilityFull details Cell population characterisation and discovery using single-cell technologies in endocrine systems Authors (2) Leonard YM CheungKarine Rizzoti Journal of Molecular Endocrinology Published 1 August 2020 Crick labsRobin Lovell-BadgeFull details SOX3 promotes generation of committed spermatogonia in postnatal mouse testes Authors (7) Dale McAninch Juho-Antti Mäkelä Hue M La James N HughesRobin Lovell-Badge Robin M Hobbs Paul Q Thomas Scientific Reports Published 21 April 2020 Crick labsRobin Lovell-BadgeFull details Oestrogen in the chick embryo can induce chromosomally maleZZ left gonad epithelial cells to form an ovarian cortex that cansupport oogenesis Authors (5)Silvana Guioli Debiao Zhao Sunil Nandi Michael ClintonRobin Lovell-Badge Development Published 25 February 2020 Crick labs/ facilitiesRobin Lovell-BadgeLight MicroscopyBiological Research FacilityFull details Pagination Current page 1 Page 2 Page 3 Page 4 Page 5 Next page Next Last page Last Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
ISSCR guidelines uphold human right to science for benefit of all Authors (3) Zubin MasterRobin Lovell-Badge Bartha Knoppers Nature Published 22 July 2021 Crick labsRobin Lovell-BadgeFull details
New guidelines for stem cell and embryo research from the ISSCR Authors (3) Eric AnthonyRobin Lovell-Badge Sean J Morrison Cell Stem Cell Published 3 June 2021 Crick labsRobin Lovell-BadgeFull details
ISSCR guidelines for stem cell research and clinical translation: The 2021 update Authors (47)Robin Lovell-Badge Eric Anthony Roger A Barker Tania Bubela Ali H Brivanlou Melissa Carpenter[...] Jun Takahashi Fuchou Tang Leigh Turner Patricia J Zettler Xiaomei Zhai Stem Cell Reports Published 8 June 2021 Crick labsKathy NiakanRobin Lovell-BadgeFull details
Stem-cell guidelines: why it was time for an update Authors (1)Robin Lovell-Badge Nature Published 27 May 2021 Crick labsRobin Lovell-BadgeFull details
Editorial: Plasticity in the vertebrate pituitary, including regulatory mechanisms Authors (3) Romain FontaineKarine Rizzoti Finn-Arne Weltzien Frontiers in Endocrinology Published 1 May 2021 Crick labsRobin Lovell-BadgeFull details
Two alternative methods for the retrieval of somatic cell populations from the mouse ovary Authors (9)Emily Frost EA FordOzlem Gunes Taylor S Boeing EL Beckett SD RomanRobin Lovell-Badge EA Mclaughlin JM Sutherland Molecular Human Reproduction Published 10 May 2021 Crick labs/ facilitiesRobin Lovell-BadgeBioinformatics and BiostatisticsFull details
Novel tools and investigative approaches for the study of oligodendrocyte precursor cells (NG2-Glia) in CNS development and disease Authors (3)Christophe GalichetRichard ClaytonRobin Lovell-Badge Frontiers in Cellular Neuroscience Published 1 April 2021 Crick labsRobin Lovell-BadgeFull details
Establishing and maintaining fertility: the importance of cell cycle arrest Authors (5)Emily FrostOzlem Gunes Taylor Mark A BakerRobin Lovell-Badge Jessie M Sutherland Genes and Development Published 1 May 2021 Crick labsRobin Lovell-BadgeFull details
CRISPR/Cas9 deletion of SOX2 regulatory region 2 (SRR2) decreases SOX2 malignant activity in glioblastoma Authors (7) A Saenz-Antoñanzas V Moncho-Amor J Auzmendi-Iriarte A Elua-PininKarine RizzotiRobin Lovell-Badge A Matheu Cancers Published 29 March 2021 Crick labsRobin Lovell-BadgeFull details
Primary sex determination in birds depends on DMRT1 dosage, but gonadal sex does not determine adult secondary sex characteristics Authors (10) Jason IoannidisOzlem Gunes Taylor Debiao Zhao Long Liu Alewo Idoko-Akoh Daoqing GongRobin Lovell-BadgeSilvana Guioli Mike J McGrew Michael Clinton Proceedings of the National Academy of Sciences of USA Published 9 March 2021 Crick labsRobin Lovell-BadgeFull details
Applications of genome editing on laboratory animals Authors (2)Christophe GalichetRobin Lovell-Badge Laboratory Animals Published 17 February 2021 Crick labsRobin Lovell-BadgeFull details
SOX2 is required independently in both stem and differentiated cells for pituitary tumorigenesis in p27-null mice Authors (6)Veronica Moncho Amor Probir ChakravartyChristophe Galichet Ander MatheuRobin Lovell-BadgeKarine Rizzoti Proceedings of the National Academy of Sciences of USA Published 16 February 2021 Crick labs/ facilitiesRobin Lovell-BadgeBioinformatics and BiostatisticsLight MicroscopyFlow CytometryBiological Research FacilityAdvanced SequencingFull details
Dentate gyrus development requires a cortical hem-derived astrocytic scaffold Authors (4)Alessia CaramelloChristophe GalichetKarine RizzotiRobin Lovell-Badge eLife Published 4 January 2021 Crick labs/ facilitiesRobin Lovell-BadgeLight MicroscopyExperimental HistopathologyBiological Research FacilityFull details
Paul S. Burgoyne (1946-2020) Authors (4)James TurnerShantha Mahadevaiah Arthur P ArnoldRobin Lovell-Badge Development Published 27 October 2020 Crick labsJames TurnerRobin Lovell-BadgeFull details
Going public with your research Authors (1)Ozlem Gunes Taylor The CRISPR Journal Published 24 August 2020 Crick labsRobin Lovell-BadgeFull details
Signal transducer and activator of transcription (STAT) 1 and STAT3 are expressed in the human ovary and have Janus kinase 1-independent functions in the COV434 human granulosa cell line Authors (8)Emily Frost EA Ford AE Peters NL Reed EA McLaughlin MA BakerRobin Lovell-Badge JM Sutherland Reproduction Fertility and Development Published 1 August 2020 Crick labsRobin Lovell-BadgeFull details
Testis formation in XX individuals resulting from novel pathogenic variants in Wilms’ tumor 1 (WT1) gene Authors (33) Caroline EozenouNitzan Gonen Maria Sol Touzon Anne Jorgensen Svetlana A Yatsenko Leila Fusee[...] Ken McElreavey Alicia BelgoroskyRobin Lovell-Badge Aleksandar Rajkovic Anu Bashamboo Proceedings of the National Academy of Sciences Published 16 June 2020 Crick labs/ facilitiesRobin Lovell-BadgeExperimental HistopathologyBiological Research FacilityFull details
Cell population characterisation and discovery using single-cell technologies in endocrine systems Authors (2) Leonard YM CheungKarine Rizzoti Journal of Molecular Endocrinology Published 1 August 2020 Crick labsRobin Lovell-BadgeFull details
SOX3 promotes generation of committed spermatogonia in postnatal mouse testes Authors (7) Dale McAninch Juho-Antti Mäkelä Hue M La James N HughesRobin Lovell-Badge Robin M Hobbs Paul Q Thomas Scientific Reports Published 21 April 2020 Crick labsRobin Lovell-BadgeFull details
Oestrogen in the chick embryo can induce chromosomally maleZZ left gonad epithelial cells to form an ovarian cortex that cansupport oogenesis Authors (5)Silvana Guioli Debiao Zhao Sunil Nandi Michael ClintonRobin Lovell-Badge Development Published 25 February 2020 Crick labs/ facilitiesRobin Lovell-BadgeLight MicroscopyBiological Research FacilityFull details
