Publications

The rates of adult neurogenesis and oligodendrogenesis are linked to cell cycle regulation through p27-dependent gene repression of SOX2

Authors (13)

Ana Domingo-Muelas
Jose Manuel Morante-Redolat
Veronica Moncho Amor
Antonio Jordán-Pla
Ana Pérez-Villalba
Pau Carrillo-Barberà
[...]
Martina Kirstein
Oriol Bachs
Sacri R Ferrón
Robin Lovell-Badge
Isabel Fariñas

Cellular and Molecular Life Sciences

Published 11 January 2023

Crick labs

Robin Lovell-Badge

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In vitro cellular reprogramming to model gonad development and its disorders

Authors (21)

Nitzan Gonen
Caroline Eozenou
Richard Mitter
Maëva Elzaiat
Isabelle Stévant
Rona Aviram
[...]
Samy Gobaa
Jim Smith
Kenneth McElreavey
Robin Lovell-Badge
Anu Bashamboo

Science advances

Published 4 January 2023

Crick labs/ facilities

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Hypomorphic and dominant-negative impact of truncated SOX9 dysregulates Hedgehog-Wnt signaling, causing campomelia

Authors (12)

Tiffany YK Au
Raymond KH Yip
Sarah L Wynn
Tiong Y Tan
Alex Fu
Yu Hong Geng
[...]
Ben Niu
Kevin Y Yip
Martin CH Cheung
Robin Lovell-Badge
Kathryn SE Cheah

Proceedings of the National Academy of Sciences of USA

Published 3 January 2023

Crick labs

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SOX9 and SOX10 control fluid homeostasis in the inner ear for hearing through independent and cooperative mechanisms

Authors (16)

Irene YY Szeto
Daniel KH Chu
Peikai Chen
Ka Chi Chu
Tiffany YK Au
Keith KH Leung
[...]
Ralf Jauch
Bernd Fritzsch
Mai Har Sham
Robin Lovell-Badge
Kathryn SE Cheah

Proceedings of the National Academy of Sciences of USA

Published 15 November 2022

Crick labs

Robin Lovell-Badge

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A new understanding, guided by single-cell sequencing, of the establishment and maintenance of the ovarian reserve in mammals

Authors (7)

Emily Frost
Emmalee A Ford
Alexandra E Peters
Robin Lovell-Badge
Gunes Taylor
Eileen A McLaughlin
Jessie M Sutherland

Sexual Development

Published 19 September 2022

Crick labs

Robin Lovell-Badge

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The cortical hem lacks stem cell potential despite expressing SOX9 and HOPX

Authors (5)

Developmental Neurobiology

Published 1 October 2022

Crick labs/ facilities

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TRIM28-dependent SUMOylation protects the adult ovary from activation of the testicular pathway

Authors (17)

Moïra Rossitto
Stephanie Déjardin
Chris M Rands
Stephanie Le Gras
Roberta Migale
Sina Rafiee
[...]
Dagmar Wilhelm
Robin Lovell-Badge
Brigitte Boizet-Bonhoure
Serge Nef
Francis Poulat

Nature Communications

Published 29 July 2022

Crick labs

Robin Lovell-Badge

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The properties and functions of glial cell types of the hypothalamic median eminence

Authors (3)

Frontiers in Endocrinology

Published 27 July 2022

Crick labs

Robin Lovell-Badge

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A homozygous Y443C variant in the RNPC3 is associated with severe syndromic congenital hypopituitarism and diffuse brain atrophy

Authors (7)

Diğdem Bezen
Orkide Kutlu
Stephane Mouilleron
Karine Rizzoti
Mehul Dattani
Tulay Guran
Gözde Yeşil

American Journal of Medical Genetics Part A

Published 1 September 2022

Crick labs/ facilities

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High SOX9 maintains glioma stem cell activity through a regulatory loop involving STAT3 and PML

Authors (14)

Paula Aldaz
Natalia Martín‐Martín
Ander Saenz‐Antoñanzas
Estefania Carrasco‐Garcia
María Álvarez‐Satta
Alejandro Elúa‐Pinin
[...]
Nicolás Samprón
Jürgen Hench
Robin Lovell-Badge
Arkaitz Carracedo
Ander Matheu

International Journal of Molecular Sciences

Published 19 April 2022

Crick labs

Robin Lovell-Badge

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SOX9 triggers different epithelial to mesenchymal transition states to promote pancreatic cancer progression

Authors (16)

Estefania Carrasco-Garcia
Lidia Lopez
Veronica Moncho Amor
Fernando Carazo
Paula Aldaz
Manuel Collado
[...]
Ángel Rubio
Manuel Serrano
Charles H Lawrie
Robin Lovell-Badge
Ander Matheu

Cancers

Published 12 February 2022

Crick labs/ facilities

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Pathogenic variants in RNPC3 are associated with hypopituitarism and primary ovarian insufficiency

Authors (30)

Leyla Akin
Karine Rizzoti
Louise C Gregory
Beatriz Corredor
Polona Le Quesne Stabej
Hywel Williams
[...]
Luis A Pérez-Jurado
Iain Robinson
Robin Lovell-Badge
Jesús Argente
Mehul T Dattani

Genetics in Medicine

Published 1 February 2022

Crick labs/ facilities

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Long-range regulation of key sex determination genes

Authors (3)

Sexual Development

Published 1 December 2021

Crick labs

Robin Lovell-Badge

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ISSCR guidelines uphold human right to science for benefit of all

Authors (3)

Zubin Master
Robin Lovell-Badge
Bartha Knoppers

Nature

Published 22 July 2021

Crick labs

Robin Lovell-Badge

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New guidelines for stem cell and embryo research from the ISSCR

Authors (3)

Eric Anthony
Robin Lovell-Badge
Sean J Morrison

Cell Stem Cell

Published 3 June 2021

Crick labs

Robin Lovell-Badge

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ISSCR guidelines for stem cell research and clinical translation: The 2021 update

Authors (47)

Robin Lovell-Badge
Eric Anthony
Roger A Barker
Tania Bubela
Ali H Brivanlou
Melissa Carpenter
[...]
Jun Takahashi
Fuchou Tang
Leigh Turner
Patricia J Zettler
Xiaomei Zhai

Stem Cell Reports

Published 8 June 2021

Crick labs

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Stem-cell guidelines: why it was time for an update

Authors (1)

Robin Lovell-Badge

Nature

Published 27 May 2021

Crick labs

Robin Lovell-Badge

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Editorial: Plasticity in the vertebrate pituitary, including regulatory mechanisms

Authors (3)

Romain Fontaine
Karine Rizzoti
Finn-Arne Weltzien

Frontiers in Endocrinology

Published 1 May 2021

Crick labs

Robin Lovell-Badge

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Two alternative methods for the retrieval of somatic cell populations from the mouse ovary

Authors (9)

Emily Frost
EA Ford
Gunes Taylor
S Boeing
EL Beckett
SD Roman
Robin Lovell-Badge
EA Mclaughlin
JM Sutherland

Molecular Human Reproduction

Published 1 June 2021

Crick labs/ facilities

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Novel tools and investigative approaches for the study of oligodendrocyte precursor cells (NG2-Glia) in CNS development and disease

Authors (3)

Frontiers in Cellular Neuroscience

Published 1 April 2021

Crick labs

Robin Lovell-Badge

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PhD student recruitment

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Coronavirus (COVID-19) research

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Publications

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The rates of adult neurogenesis and oligodendrogenesis are linked to cell cycle regulation through p27-dependent gene repression of SOX2

In vitro cellular reprogramming to model gonad development and its disorders

Hypomorphic and dominant-negative impact of truncated SOX9 dysregulates Hedgehog-Wnt signaling, causing campomelia

SOX9 and SOX10 control fluid homeostasis in the inner ear for hearing through independent and cooperative mechanisms

A new understanding, guided by single-cell sequencing, of the establishment and maintenance of the ovarian reserve in mammals

The cortical hem lacks stem cell potential despite expressing SOX9 and HOPX

TRIM28-dependent SUMOylation protects the adult ovary from activation of the testicular pathway

The properties and functions of glial cell types of the hypothalamic median eminence

A homozygous Y443C variant in the RNPC3 is associated with severe syndromic congenital hypopituitarism and diffuse brain atrophy

High SOX9 maintains glioma stem cell activity through a regulatory loop involving STAT3 and PML

SOX9 triggers different epithelial to mesenchymal transition states to promote pancreatic cancer progression

Pathogenic variants in RNPC3 are associated with hypopituitarism and primary ovarian insufficiency

Long-range regulation of key sex determination genes

ISSCR guidelines uphold human right to science for benefit of all

New guidelines for stem cell and embryo research from the ISSCR

ISSCR guidelines for stem cell research and clinical translation: The 2021 update

Stem-cell guidelines: why it was time for an update

Editorial: Plasticity in the vertebrate pituitary, including regulatory mechanisms

Two alternative methods for the retrieval of somatic cell populations from the mouse ovary

Novel tools and investigative approaches for the study of oligodendrocyte precursor cells (NG2-Glia) in CNS development and disease

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Research case studies

PhD student recruitment

Cut + Paste exhibition

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Research topics

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