Publications

Beyond the primary tumour: Rethinking biomarker strategies in recurrent renal cell carcinoma

Authors (3)

Zayd Tippu
Lewis Au
Samra Turajlic

European Urology

Published 26 June 2026

Crick labs

Samra Turajlic

Full details

Advanced imaging of immune cells for human kidney disease

Authors (7)

Candice Roufosse
Omar Bouricha
Alana Burrell
Maria Prendecki
Samra Turajlic
Tabitha Turner-Stokes
Lucy Collinson

Trends in Molecular Medicine

Published 29 May 2026

Crick labs/ facilities

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Use of circulating tumour DNA to prospectively guide a switch from targeted to immune therapy in BRAF mutant advanced melanoma: the randomised phase II CAcTUS trial

Authors (24)

Rebecca J Lee
Dominic G Rothwell
Nigel Smith
Shien Chow
Juan Delgado-SanMartin
Hitesh Mistry
[...]
Samra Turajlic
Florent Mouliere
Richard Marais
Caroline Dive
Paul Lorigan

Nature Communications

Published 21 May 2026

Crick labs

Samra Turajlic

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Immunotherapy drug target identification using machine learning and patient-derived tumour explant validation

Authors (20)

Marcellus Augustine
Nuno Rocha Nene
Hongchang Fu
Christopher L Pinder
Lorena Ligammari
Alexander P Simpson
[...]
Sergio A Quezada
Nicholas McGranahan
Chris Watkins
Charles Swanton
Kevin Litchfield

Nature Machine Intelligence

Published 1 May 2026

Crick labs/ facilities

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Distinct functions of PBRM1 and BAP1 reconcile the course of kidney cancer evolution and disease progression

Preprint

Authors (35)

Daqi Deng
Geoffrey Feng
Annika Fendler
Yuliia Dovga
Fiona Byrne
Charlotte Spencer
[...]
Leo Bickley
Sarah Rudman
Axel Bex
James Larkin
Samra Turajlic

bioRxiv

Published 3 May 2026

Crick labs/ facilities

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Intratumoural bacteria promote myeloid inflammation and disease progression in clear cell Renal Cell Carcinoma: TRACERx Renal

Preprint

Authors (29)

Alice Martin
Anne-Laure Cattin
Parise Lockwood
Martha A Zepeda-Rivera
Clara Becker
Taja Barber
[...]
Sarah Rudman
James Larkin
Kevin Litchfield
Maximiliano Gutierrez
Samra Turajlic

SSRN

Published 2 May 2026

Crick labs/ facilities

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Evolutionary characterization of lung cancer metastasis

Authors (66)

Sonya Hessey
Abigail Bunkum
Ariana Huebner
Kerstin Haase
Kristiana Grigoriadis
Cristina Naceur-Lombardelli
[...]
David A Moore
Simone Zaccaria
Nicholas McGranahan
Charles Swanton
Mariam Jamal-Hanjani

Nature

Published 21 May 2026

Crick labs/ facilities

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Zenodo deposit: Evolutionary Characterisation of Lung Cancer Metastasis

Authors (3)

Ariana Huebner
Kristiana Grigoriadis
Charles Swanton

Zenodo

Published 24 April 2026

Crick labs/ facilities

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Immunometabolic gatekeeping: How tissue metabolism conditions tumor immunity

Authors (7)

Naomi van den Berg
Matous Elphick
Kevin Mulder
Omar Bouricha
Omid Sadeghi-Alavijeh
Xiao Fu
Samra Turajlic

Cancer Cell

Published 13 April 2026

Crick labs

Samra Turajlic

Full details

Efficacy and safety of stereotactic radiosurgery (SRS) in the management of brain metastases in patients with metastatic melanoma

Authors (16)

DJ McMahon
M Aboulela
J De Boisanger
JJ Soto-Castillo
C Beland
S Cheruvu
[...]
L Pickering
L Welsh
N Rosenfelder
J Larkin
F Solda

British Journal of Radiology

Published 1 May 2026

Crick labs

Samra Turajlic

Full details

Contrasting features of papillary and chromophobe renal cell carcinoma revealed by whole genome sequencing

Authors (16)

Richard Culliford
Charlie Mills
Daniel Chubb
Ben Kinnersley
Amit Sud
Alex J Cornish
[...]
Kevin Litchfield
David C Wedge
James Larkin
Samra Turajlic
Richard S Houlston

Molecular Cancer Research

Published 1 May 2026

Crick labs

Samra Turajlic

Full details

Cross-presentation of dead cell-associated antigens shapes the neoantigenic landscape of tumor immunity

Authors (21)

Jonathan Lim
Oliver Schulz
Irene Lobon
Tom Castro Dopico
Luis Zapata
Evangelos Giampazolias
[...]
Stephanie Maiocco
Raj Mehta
Jessica Strid
Samra Turajlic
Caetano Reis e Sousa

Nature Immunology

Published 1 January 2026

Crick labs/ facilities

Full details

Data associated with: Somatic evolution following cancer treatment in normal tissue

Authors (1)

Charles Swanton

European Genome-phenome Archive (EGA)

Published 24 December 2025

Crick labs/ facilities

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TRACERx as an optimized paradigm for understanding cancer evolution

Authors (3)

Annual Review of Cancer Biology

Published 1 May 2026

Crick labs/ facilities

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Long-term real-world survival outcomes with dual immune checkpoint blockade in synchronous metastatic renal cell carcinoma: Implications for the design of prospective cytoreductive nephrectomy trials

Authors (15)

L Bickley
EE Fransen van de Putte
L van den Brink
L Marandino
JC van der Mijn
S Wilgenhof
[...]
PJ Zondervan
NM Graafland
Z Tippu
Samra Turajlic
A Bex

European Urology Open Science

Published 1 January 2026

Crick labs

Samra Turajlic

Full details

Code associated with: Somatic evolution following cancer treatment in normal tissue

Authors (1)

Charles Swanton

GitHub

Published 10 December 2025

Crick labs/ facilities

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Somatic evolution following cancer treatment in normal tissue

Authors (23)

Oriol Pich
Sophie Ward
Andrew Rowan
Cristina Naceur-Lombardelli
Oliver Shutkever
Carlos Martinez-Ruiz
[...]
Crispin T Hiley
PEACE Consortium
Charles Swanton
Mariam Jamal-Hanjani
Nicholas McGranahan

Nature

Published 21 May 2026

Crick labs/ facilities

Full details

EGA entry EGAD00001015763: PEACE (Posthumous Evaluation of Advanced Cancer Environment) whole exome sequencing data

Authors (1)

Charles Swanton

European Genome-phenome Archive (EGA)

Published 27 October 2025

Crick labs/ facilities

Full details

EGA entry EGAS00001008217: PEACE lung - Whole exome multiregion sequencing data

Authors (1)

Charles Swanton

European Genome-phenome Archive (EGA)

Published 27 October 2025

Crick labs/ facilities

Full details

Combining immunotherapies with standard therapies in the treatment of cancer

Authors (3)

Elizabeth Appleton
Jennifer Thomas
Samra Turajlic

Encyclopedia of Immunobiology

Published 1 January 2026

Crick labs

Samra Turajlic

Full details

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Lab content

Beyond the primary tumour: Rethinking biomarker strategies in recurrent renal cell carcinoma

Advanced imaging of immune cells for human kidney disease

Use of circulating tumour DNA to prospectively guide a switch from targeted to immune therapy in BRAF mutant advanced melanoma: the randomised phase II CAcTUS trial

Immunotherapy drug target identification using machine learning and patient-derived tumour explant validation

Distinct functions of PBRM1 and BAP1 reconcile the course of kidney cancer evolution and disease progression

Intratumoural bacteria promote myeloid inflammation and disease progression in clear cell Renal Cell Carcinoma: TRACERx Renal

Evolutionary characterization of lung cancer metastasis

Zenodo deposit: Evolutionary Characterisation of Lung Cancer Metastasis

Immunometabolic gatekeeping: How tissue metabolism conditions tumor immunity

Efficacy and safety of stereotactic radiosurgery (SRS) in the management of brain metastases in patients with metastatic melanoma

Contrasting features of papillary and chromophobe renal cell carcinoma revealed by whole genome sequencing

Cross-presentation of dead cell-associated antigens shapes the neoantigenic landscape of tumor immunity

Data associated with: Somatic evolution following cancer treatment in normal tissue

TRACERx as an optimized paradigm for understanding cancer evolution

Long-term real-world survival outcomes with dual immune checkpoint blockade in synchronous metastatic renal cell carcinoma: Implications for the design of prospective cytoreductive nephrectomy trials

Code associated with: Somatic evolution following cancer treatment in normal tissue

Somatic evolution following cancer treatment in normal tissue

EGA entry EGAD00001015763: PEACE (Posthumous Evaluation of Advanced Cancer Environment) whole exome sequencing data

EGA entry EGAS00001008217: PEACE lung - Whole exome multiregion sequencing data

Combining immunotherapies with standard therapies in the treatment of cancer

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Research partnerships

Technical training

We Go Way Back

About us

The Crick magazine

Lab content

Publications

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