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Breadcrumb Samra Turajlic Turajlic lab Cancer Dynamics Laboratory : Publications Lab contentLab contentIn this section Overview Publications Areas of interest Vacancies Members Publications Displaying 1 - 20 of 111Last updated : 24 April 2024 03:23 Therapeutic inhibition of monocyte recruitment prevents checkpoint inhibitor-induced hepatitis Authors (13) Cathrin LC Gudd Eoin Mitchell Stephen R Atkinson Marie-Anne MawhinSamra Turajlic James Larkin[...] Nick Powell Charalambos G Antoniades Kevin J Woollard Lucia A Possamai Evangelos Triantafyllou Journal for ImmunoTherapy of Cancer Published 4 April 2024 Crick labsSamra TurajlicFull details Nilotinib in KIT-driven advanced melanoma: Results from the phase II single-arm NICAM trial Authors (23) James Larkin Richard Marais Nuria Porta David Gonzalez de Castro Lisa Parsons Christina Messiou[...] Christian Ottensmeier Ruth Plummer Judith Bliss Sara ValpioneSamra Turajlic Cell Reports Medicine Published 19 March 2024 Crick labsSamra TurajlicFull details The artificial intelligence-based model ANORAK improves histopathological grading of lung adenocarcinoma Authors (20) Xiaoxi Pan Khalid AbdulJabbar Jose Coelho-Lima Anca-Ioana Grapa Hanyun Zhang Alvin Ho Kwan Cheung[...] TRACERx ConsortiumCharles Swanton Yinyin Yuan John Le Quesne David A Moore Nature Cancer Published 1 February 2024 Crick labs/ facilitiesPeter Van LooSamra TurajlicCharles SwantonErik SahaiGeorge KassiotisFlow CytometryExperimental HistopathologyBiological Research FacilityBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details Response to the letter entitled ‘On finding acceptance’ Authors (5) KHJ Lim CB Westphalen J Mateo M Lambertini T Amaral ESMO Open Published 1 December 2023 Crick labsSamra TurajlicFull details Artificial intelligence for predictive biomarker discovery in immuno-oncology: a systematic review Authors (30) A Prelaj V Miskovic M Zanitti F Trovo C Genova G Viscardi[...] F de Braud MC Garassino G Pentheroudakis C Spencer ALG Pedrocchi Annals of Oncology Published 1 January 2024 Crick labsSamra TurajlicFull details Young oncologists' perspective on the role and future of the clinician-scientist in oncology Authors (30) KHJ Lim CB Westphalen AS Berghoff C Cardone EA Connolly DC Güven[...] E de Azambuja A Cervantes M Lambertini J Mateo T Amaral ESMO Open Published 1 October 2023 Crick labsSamra TurajlicFull details Interpretability of radiomics models is improved when using feature group selection strategies for predicting molecular and clinical targets in clear-cell renal cell carcinoma: insights from the TRACERx Renal study Authors (16) Matthew R Orton Evan Hann Simon J DoranScott Shepherd Derfel Ap Dafydd Charlotte E Spencer[...] Christina Messiou James LarkinSamra Turajlic TRACERx Renal Consortium Dow-Mu Koh Cancer Imaging Published 14 August 2023 Crick labsSamra TurajlicFull details Copy number architectures define treatment-mediated selection of lethal prostate cancer clones Authors (24) AM Mahedi Hasan Paolo Cremaschi Daniel Wetterskog Anuradha Jayaram Stephen Q Wong Scott Williams[...]Charles Swanton Mariam Jamal-Hanjani Stefano Lise Shahneen Sandhu Gerhardt Attard Nature Communications Published 10 August 2023 Crick labs/ facilitiesPeter Van LooSamra TurajlicCharles SwantonPeter ParkerExperimental HistopathologyBiological Research FacilityAdvanced SequencingFull details Interferon signaling promotes tolerance to chromosomal instability during metastatic evolution in renal cancer Authors (44) Luigi Perelli Federica Carbone Li Zhang Justin K Huang Courtney Le Hania Khan[...] Andrea Viale Christopher A Bristow Nizar M Tannir Alessandro Carugo Giannicola Genovese Nature Cancer Published 1 July 2023 Crick labsSamra TurajlicFull details Independent SARS-CoV-2 staff testing protected academic and health-care institutions in northwest London Authors (54) Chris BaileyTheo Sanderson Hermaleigh Townsley Jacki Goldman James RM BlackGeorge Young[...]Jerome NicodSonia GandhiDavid LV Bauer Emma C WallCharles Swanton The Lancet Published 1 July 2023 Crick labs/ facilitiesSamra TurajlicCharles SwantonSam RodriquesSonia GandhiSteve GamblinMike BlackmanRupert BealeDavid LV BauerWorldwide Influenza CentreStructural BiologyMetabolomicsHigh Throughput ScreeningFlow CytometryBioinformatics and BiostatisticsAdvanced SequencingScientific computingBiological Research FacilityFull details Immuno-oncology approaches in uveal melanoma: tebentafusp and beyond Authors (4) C Gerard B Shum P NathanSamra Turajlic Immuno-Oncology and Technology Published 1 September 2023 Crick labsSamra TurajlicFull details Sotrovimab restores neutralization against current Omicron subvariants in patients with blood cancer Authors (67)Mary WuScott Shepherd Annika FendlerEdward CarrLewis Au Ruth Harvey[...] Emma Nicholson James Larkin Emma C WallSamra Turajlic CAPTURE consortium Cancer Cell Published 8 May 2023 Crick labs/ facilitiesSamra TurajlicCharles SwantonNicola LewisGeorge KassiotisSonia GandhiSteve GamblinRupert BealeDavid LV BauerWorldwide Influenza CentreMetabolomicsHigh Throughput ScreeningBioinformatics and BiostatisticsScientific computingFull details Antibodies against endogenous retroviruses promote lung cancer immunotherapy Authors (51)Kevin NgJesse BoumelhaKatey EnfieldJorge Almagro Hongui Cha Oriol Pich[...] Se-Hoon LeeSamra TurajlicCharles SwantonJulian DownwardGeorge Kassiotis Nature Published 20 April 2023 Crick labs/ facilitiesRobert J WilkinsonPeter Van LooSamra TurajlicCharles SwantonGeorge KassiotisJulian DownwardAxel BehrensFlow CytometryExperimental HistopathologyBioinformatics and BiostatisticsAdvanced SequencingScientific computingProteomicsLight MicroscopyCell ServicesBiological Research FacilityFull details Late-stage metastatic melanoma emerges through a diversity of evolutionary pathways Authors (71)Lavina SpainAlex CoultonIrene LobonAndrew RowanDesiree SchnidrigScott Shepherd[...] Kevin LitchfieldCharles Swanton Mariam Jamal-Hanjani The PEACE ConsortiumSamra Turajlic Cancer Discovery Published 1 June 2023 Crick labs/ facilitiesSamra TurajlicCharles SwantonExperimental HistopathologyFull details TCR sequencing: applications in immuno-oncology research Authors (5) ÁF Sanromán K JoshiLewis Au B ChainSamra Turajlic Immuno-Oncology and Technology Published 1 March 2023 Crick labsSamra TurajlicFull details Relatlimab and nivolumab in the treatment of melanoma Authors (3)Lewis Au James LarkinSamra Turajlic Cell Published 22 December 2022 Crick labsSamra TurajlicFull details The road to systemic therapy in von Hippel-Lindau (VHL) disease: Are we there yet? Authors (3)Scott Shepherd William M DrakeSamra Turajlic European Journal of Cancer Published 1 March 2023 Crick labsSamra TurajlicFull details Checkpoint inhibitor therapy and psoriasis: a case series Authors (8) Khawar Hussain Alpa Kanji Shirin Zaheri Dalila Malek Monica Terlizzo Justin WeirSamra Turajlic Louise Fearfield Clinical and Experimental Dermatology Published 29 November 2022 Crick labsSamra TurajlicFull details The spectrum of cardiovascular complications related to immune-checkpoint inhibitor treatment : Including myocarditis and the new entity of non inflammatory left ventricular dysfunction Authors (17) Maria Sol Andres Sivatharshini Ramalingam Stuart D Rosen John Baksi Rajdeep Khattar Yulia Kirichenko[...]Samra Turajlic Lisa Pickering Sanjay Popat James Larkin Alexander R Lyon Cardio-Oncology Published 24 November 2022 Crick labsSamra TurajlicFull details The WHO 2022 classification of penile and scrotal cancers: updates and evolution Authors (16) S Menon H Moch DM Berney IA Cree JR Srigley T Tsuzuki[...]Samra Turajlic PH Tan MR Raspollini SK Tickoo MB Amin Histopathology Published 1 March 2023 Crick labsSamra TurajlicFull details Pagination Current page 1 Page 2 Page 3 Page 4 Page 5 Page 6 Next page Next Last page Last Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Therapeutic inhibition of monocyte recruitment prevents checkpoint inhibitor-induced hepatitis Authors (13) Cathrin LC Gudd Eoin Mitchell Stephen R Atkinson Marie-Anne MawhinSamra Turajlic James Larkin[...] Nick Powell Charalambos G Antoniades Kevin J Woollard Lucia A Possamai Evangelos Triantafyllou Journal for ImmunoTherapy of Cancer Published 4 April 2024 Crick labsSamra TurajlicFull details
Nilotinib in KIT-driven advanced melanoma: Results from the phase II single-arm NICAM trial Authors (23) James Larkin Richard Marais Nuria Porta David Gonzalez de Castro Lisa Parsons Christina Messiou[...] Christian Ottensmeier Ruth Plummer Judith Bliss Sara ValpioneSamra Turajlic Cell Reports Medicine Published 19 March 2024 Crick labsSamra TurajlicFull details
The artificial intelligence-based model ANORAK improves histopathological grading of lung adenocarcinoma Authors (20) Xiaoxi Pan Khalid AbdulJabbar Jose Coelho-Lima Anca-Ioana Grapa Hanyun Zhang Alvin Ho Kwan Cheung[...] TRACERx ConsortiumCharles Swanton Yinyin Yuan John Le Quesne David A Moore Nature Cancer Published 1 February 2024 Crick labs/ facilitiesPeter Van LooSamra TurajlicCharles SwantonErik SahaiGeorge KassiotisFlow CytometryExperimental HistopathologyBiological Research FacilityBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details
Response to the letter entitled ‘On finding acceptance’ Authors (5) KHJ Lim CB Westphalen J Mateo M Lambertini T Amaral ESMO Open Published 1 December 2023 Crick labsSamra TurajlicFull details
Artificial intelligence for predictive biomarker discovery in immuno-oncology: a systematic review Authors (30) A Prelaj V Miskovic M Zanitti F Trovo C Genova G Viscardi[...] F de Braud MC Garassino G Pentheroudakis C Spencer ALG Pedrocchi Annals of Oncology Published 1 January 2024 Crick labsSamra TurajlicFull details
Young oncologists' perspective on the role and future of the clinician-scientist in oncology Authors (30) KHJ Lim CB Westphalen AS Berghoff C Cardone EA Connolly DC Güven[...] E de Azambuja A Cervantes M Lambertini J Mateo T Amaral ESMO Open Published 1 October 2023 Crick labsSamra TurajlicFull details
Interpretability of radiomics models is improved when using feature group selection strategies for predicting molecular and clinical targets in clear-cell renal cell carcinoma: insights from the TRACERx Renal study Authors (16) Matthew R Orton Evan Hann Simon J DoranScott Shepherd Derfel Ap Dafydd Charlotte E Spencer[...] Christina Messiou James LarkinSamra Turajlic TRACERx Renal Consortium Dow-Mu Koh Cancer Imaging Published 14 August 2023 Crick labsSamra TurajlicFull details
Copy number architectures define treatment-mediated selection of lethal prostate cancer clones Authors (24) AM Mahedi Hasan Paolo Cremaschi Daniel Wetterskog Anuradha Jayaram Stephen Q Wong Scott Williams[...]Charles Swanton Mariam Jamal-Hanjani Stefano Lise Shahneen Sandhu Gerhardt Attard Nature Communications Published 10 August 2023 Crick labs/ facilitiesPeter Van LooSamra TurajlicCharles SwantonPeter ParkerExperimental HistopathologyBiological Research FacilityAdvanced SequencingFull details
Interferon signaling promotes tolerance to chromosomal instability during metastatic evolution in renal cancer Authors (44) Luigi Perelli Federica Carbone Li Zhang Justin K Huang Courtney Le Hania Khan[...] Andrea Viale Christopher A Bristow Nizar M Tannir Alessandro Carugo Giannicola Genovese Nature Cancer Published 1 July 2023 Crick labsSamra TurajlicFull details
Independent SARS-CoV-2 staff testing protected academic and health-care institutions in northwest London Authors (54) Chris BaileyTheo Sanderson Hermaleigh Townsley Jacki Goldman James RM BlackGeorge Young[...]Jerome NicodSonia GandhiDavid LV Bauer Emma C WallCharles Swanton The Lancet Published 1 July 2023 Crick labs/ facilitiesSamra TurajlicCharles SwantonSam RodriquesSonia GandhiSteve GamblinMike BlackmanRupert BealeDavid LV BauerWorldwide Influenza CentreStructural BiologyMetabolomicsHigh Throughput ScreeningFlow CytometryBioinformatics and BiostatisticsAdvanced SequencingScientific computingBiological Research FacilityFull details
Immuno-oncology approaches in uveal melanoma: tebentafusp and beyond Authors (4) C Gerard B Shum P NathanSamra Turajlic Immuno-Oncology and Technology Published 1 September 2023 Crick labsSamra TurajlicFull details
Sotrovimab restores neutralization against current Omicron subvariants in patients with blood cancer Authors (67)Mary WuScott Shepherd Annika FendlerEdward CarrLewis Au Ruth Harvey[...] Emma Nicholson James Larkin Emma C WallSamra Turajlic CAPTURE consortium Cancer Cell Published 8 May 2023 Crick labs/ facilitiesSamra TurajlicCharles SwantonNicola LewisGeorge KassiotisSonia GandhiSteve GamblinRupert BealeDavid LV BauerWorldwide Influenza CentreMetabolomicsHigh Throughput ScreeningBioinformatics and BiostatisticsScientific computingFull details
Antibodies against endogenous retroviruses promote lung cancer immunotherapy Authors (51)Kevin NgJesse BoumelhaKatey EnfieldJorge Almagro Hongui Cha Oriol Pich[...] Se-Hoon LeeSamra TurajlicCharles SwantonJulian DownwardGeorge Kassiotis Nature Published 20 April 2023 Crick labs/ facilitiesRobert J WilkinsonPeter Van LooSamra TurajlicCharles SwantonGeorge KassiotisJulian DownwardAxel BehrensFlow CytometryExperimental HistopathologyBioinformatics and BiostatisticsAdvanced SequencingScientific computingProteomicsLight MicroscopyCell ServicesBiological Research FacilityFull details
Late-stage metastatic melanoma emerges through a diversity of evolutionary pathways Authors (71)Lavina SpainAlex CoultonIrene LobonAndrew RowanDesiree SchnidrigScott Shepherd[...] Kevin LitchfieldCharles Swanton Mariam Jamal-Hanjani The PEACE ConsortiumSamra Turajlic Cancer Discovery Published 1 June 2023 Crick labs/ facilitiesSamra TurajlicCharles SwantonExperimental HistopathologyFull details
TCR sequencing: applications in immuno-oncology research Authors (5) ÁF Sanromán K JoshiLewis Au B ChainSamra Turajlic Immuno-Oncology and Technology Published 1 March 2023 Crick labsSamra TurajlicFull details
Relatlimab and nivolumab in the treatment of melanoma Authors (3)Lewis Au James LarkinSamra Turajlic Cell Published 22 December 2022 Crick labsSamra TurajlicFull details
The road to systemic therapy in von Hippel-Lindau (VHL) disease: Are we there yet? Authors (3)Scott Shepherd William M DrakeSamra Turajlic European Journal of Cancer Published 1 March 2023 Crick labsSamra TurajlicFull details
Checkpoint inhibitor therapy and psoriasis: a case series Authors (8) Khawar Hussain Alpa Kanji Shirin Zaheri Dalila Malek Monica Terlizzo Justin WeirSamra Turajlic Louise Fearfield Clinical and Experimental Dermatology Published 29 November 2022 Crick labsSamra TurajlicFull details
The spectrum of cardiovascular complications related to immune-checkpoint inhibitor treatment : Including myocarditis and the new entity of non inflammatory left ventricular dysfunction Authors (17) Maria Sol Andres Sivatharshini Ramalingam Stuart D Rosen John Baksi Rajdeep Khattar Yulia Kirichenko[...]Samra Turajlic Lisa Pickering Sanjay Popat James Larkin Alexander R Lyon Cardio-Oncology Published 24 November 2022 Crick labsSamra TurajlicFull details
The WHO 2022 classification of penile and scrotal cancers: updates and evolution Authors (16) S Menon H Moch DM Berney IA Cree JR Srigley T Tsuzuki[...]Samra Turajlic PH Tan MR Raspollini SK Tickoo MB Amin Histopathology Published 1 March 2023 Crick labsSamra TurajlicFull details
