Ultanir lab

Kinases and Brain Development Laboratory

: Areas of interest

We propose using our kinase substrate identification method to reveal the substrates and phosphorylation sites of CDKL5.

Mechanistic target of rapamycin (mTOR) is a serine/threonine protein kinase which regulates cell growth downstream of nutrition availability and plays roles in neural stem cell proliferation and differentiation.

TRAF2 And Nck Interacting Kinase (TNIK) is a serine/threonine kinase in the Ste20-like family of kinases. 

Nuclear Dbf2 Related (NDR) kinases NDR1 and NDR2 are part of the AGC group of serine/ threonine kinases and together with LATS1/2 form the NDR family of kinase.