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Breadcrumb Simon Boulton Boulton lab DSB Repair Metabolism Laboratory : Publications Lab contentLab contentIn this section Overview Vacancies Areas of interest Publications Members DNA damage in mouse embryonic stem cells. Credit: Paulina Marzec. Toggle to view hero caption PublicationsYear published2023 (1)2021 (1)2020 (1)2019 (1)2017 (1)2015 (2)2013 (1)2010 (1) Facet Year publishedResearch topicsBiochemistry & Proteomics (5)Cell Biology (5)Cell Cycle & Chromosomes (5)Genetics & Genomics (5)Genome Integrity & Repair (5)Model Organisms (5)Chemical Biology & High Throughput (3)Computational & Systems Biology (3)Developmental Biology (1)Gene Expression (1)Neurosciences (1)Signalling & Oncogenes (1)Structural Biology & Biophysics (1)Synthetic Biology (1) Facet Research topicsPublication typeJournal article (9)Primary research (8)Editorial (1) Facet Publication typeJournal (-)Nature (9) Facet Journal Publications Displaying 1 - 9 of 9Last updated : 29 March 2024 03:07 Structure and function of the RAD51B-RAD51C-RAD51D-XRCC2 tumour suppressor Authors (10)Luke GreenhoughEric Chih-Chao LiangOndrej BelanSimone Kunzelmann Sarah MaslenMonica Rodrigo BrenniRoopesh AnandMark SkehelSimon BoultonStephen West Nature Published 20 July 2023 Crick labs/ facilitiesStephen WestSimon BoultonStructural BiologyProteomicsElectron MicroscopyFull details HELQ is a dual-function DSB repair enzyme modulated by RPA and RAD51 Authors (10)Roopesh Anand Erika BuechelmaierOndrej BelanMatt NewtonAleksandra Vancevska Artur KaczmarczykTohru Takaki David S Rueda Simon N PowellSimon Boulton Nature Published 13 January 2022 Crick labsSimon BoultonFull details TRF2-independent chromosome end protection during pluripotency Authors (13)Phil Ruis David Van LyValerie Borel Georgia R KaferAfshan Mccarthy Steven Howell[...]James BriscoeKathy NiakanPaulina Marzec Anthony J CesareSimon Boulton Nature Published 7 January 2021 Crick labs/ facilitiesKathy NiakanJames BriscoeSimon BoultonProteomicsGenetic Modification ServiceBiological Research FacilityFull details CDK phosphorylation of TRF2 controls t-loop dynamics during the cell cycle Authors (12) Grzegorz SarekPanagiotis KotsantisPhil Ruis David Van Ly Pol MargalefValerie Borel[...] Helen R FlynnBram Snijders Dipanjan Chowdhury Anthony J CesareSimon Boulton Nature Published 13 November 2019 Crick labs/ facilitiesSimon BoultonProteomicsFull details Regulation of DNA repair pathway choice in S and G2 phases by the NHEJ inhibitor CYREN Authors (11) Nausica Arnoult Adriana Correia Jiao Ma Anna Merlo Sara Garcia-GomezMarija Maric Marco Tognetti Christopher W BennerSimon Boulton Alan Saghatelian Jan Karlseder Nature Published 28 September 2017 Crick labsSimon BoultonFull details REV7 counteracts DNA double-strand break resection and affects PARP inhibition Authors (30) Guotai Xu J Ross Chapman Inger Brandsma Jingsong Yuan Martin Mistrik Peter Bouwman[...] Dik C van Gent Jiri Bartek Jos Jonkers Piet Borst Sven Rottenberg Nature Published 28 May 2015 Crick labsSimon BoultonFull details Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair Authors (12) Raphael Ceccaldi Jessica C Liu Ravindra Amunugama Ildiko Hajdu Benjamin Primack Mark IR Petalcorin[...] Panagiotis A Konstantinopoulos Stephen J ElledgeSimon Boulton Timur Yusufzai Alan D D'Andrea Nature Published 12 February 2015 Crick labsSimon BoultonFull details HELQ promotes RAD51 paralogue-dependent repair to avert germ cell loss and tumorigenesis Authors (14) Carrie A Adelman Rafal L LoloNicolai Birkbak Olga Murina Kenichiro Matsuzaki Zuzana Horejsi[...] Gordon Stamp Alan D'Andrea Alessandro A SartoriCharles SwantonSimon Boulton Nature Published 17 October 2013 Crick labs/ facilitiesCharles SwantonSimon BoultonExperimental HistopathologyFull details DNA repair: Decision at the break point Authors (1)Simon Boulton Nature Published 20 May 2010 Crick labsSimon BoultonFull details Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Structure and function of the RAD51B-RAD51C-RAD51D-XRCC2 tumour suppressor Authors (10)Luke GreenhoughEric Chih-Chao LiangOndrej BelanSimone Kunzelmann Sarah MaslenMonica Rodrigo BrenniRoopesh AnandMark SkehelSimon BoultonStephen West Nature Published 20 July 2023 Crick labs/ facilitiesStephen WestSimon BoultonStructural BiologyProteomicsElectron MicroscopyFull details
HELQ is a dual-function DSB repair enzyme modulated by RPA and RAD51 Authors (10)Roopesh Anand Erika BuechelmaierOndrej BelanMatt NewtonAleksandra Vancevska Artur KaczmarczykTohru Takaki David S Rueda Simon N PowellSimon Boulton Nature Published 13 January 2022 Crick labsSimon BoultonFull details
TRF2-independent chromosome end protection during pluripotency Authors (13)Phil Ruis David Van LyValerie Borel Georgia R KaferAfshan Mccarthy Steven Howell[...]James BriscoeKathy NiakanPaulina Marzec Anthony J CesareSimon Boulton Nature Published 7 January 2021 Crick labs/ facilitiesKathy NiakanJames BriscoeSimon BoultonProteomicsGenetic Modification ServiceBiological Research FacilityFull details
CDK phosphorylation of TRF2 controls t-loop dynamics during the cell cycle Authors (12) Grzegorz SarekPanagiotis KotsantisPhil Ruis David Van Ly Pol MargalefValerie Borel[...] Helen R FlynnBram Snijders Dipanjan Chowdhury Anthony J CesareSimon Boulton Nature Published 13 November 2019 Crick labs/ facilitiesSimon BoultonProteomicsFull details
Regulation of DNA repair pathway choice in S and G2 phases by the NHEJ inhibitor CYREN Authors (11) Nausica Arnoult Adriana Correia Jiao Ma Anna Merlo Sara Garcia-GomezMarija Maric Marco Tognetti Christopher W BennerSimon Boulton Alan Saghatelian Jan Karlseder Nature Published 28 September 2017 Crick labsSimon BoultonFull details
REV7 counteracts DNA double-strand break resection and affects PARP inhibition Authors (30) Guotai Xu J Ross Chapman Inger Brandsma Jingsong Yuan Martin Mistrik Peter Bouwman[...] Dik C van Gent Jiri Bartek Jos Jonkers Piet Borst Sven Rottenberg Nature Published 28 May 2015 Crick labsSimon BoultonFull details
Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair Authors (12) Raphael Ceccaldi Jessica C Liu Ravindra Amunugama Ildiko Hajdu Benjamin Primack Mark IR Petalcorin[...] Panagiotis A Konstantinopoulos Stephen J ElledgeSimon Boulton Timur Yusufzai Alan D D'Andrea Nature Published 12 February 2015 Crick labsSimon BoultonFull details
HELQ promotes RAD51 paralogue-dependent repair to avert germ cell loss and tumorigenesis Authors (14) Carrie A Adelman Rafal L LoloNicolai Birkbak Olga Murina Kenichiro Matsuzaki Zuzana Horejsi[...] Gordon Stamp Alan D'Andrea Alessandro A SartoriCharles SwantonSimon Boulton Nature Published 17 October 2013 Crick labs/ facilitiesCharles SwantonSimon BoultonExperimental HistopathologyFull details
DNA repair: Decision at the break point Authors (1)Simon Boulton Nature Published 20 May 2010 Crick labsSimon BoultonFull details