Boulton lab
DSB Repair Metabolism Laboratory
: Publications

Publications

Displaying 61 - 80 of 103

Last updated : 19 April 2024 02:55

Repair, reuse, recycle: The expanding role of autophagy in genome maintenance

Authors (2)

G Hewitt
VI Korolchuk

Trends in Cell Biology

Published 1 May 2017

Crick labs

Simon Boulton

Full details

MRE11 stability is regulated by CK2-dependent interaction with R2TP complex

Authors (8)

P von Morgen
K Burdova
TG Flower
Nicola O'Reilly
Simon Boulton
SJ Smerdon
L Macurek
Z Hořejší

Oncogene

Published 1 August 2017

Crick labs/ facilities

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Human RIF1 and protein phosphatase 1 stimulate DNA replication origin licensing but suppress origin activation

Authors (10)

Shin-ichiro Hiraga
Tony Ly
Javier Garzón
Zuzana Horejsí
Yoshi-nobu Ohkubo
Akinori Endo
Chikashi Obuse
Simon Boulton
Angus I Lamond
Anne D Donaldson

EMBO Reports

Published 1 March 2017

Crick labs

Simon Boulton

Full details

A polar and nucleotide-dependent mechanism of action for RAD51 paralogs in RAD51 filament remodeling

Authors (9)

Martin RG Taylor
Mário Špírek
Chu Jian Ma
Raffaella Carzaniga
Tohru Takaki
Lucy Collinson
Eric C Greene
Lumir Krejci
Simon Boulton

Molecular Cell

Published 1 December 2016

Crick labs/ facilities

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Mechanism and regulation of DNA-protein crosslink repair by the DNA-dependent metalloprotease SPRTN

Authors (13)

Julian Stingele
Roberto Bellelli
Ferdinand Alte
Graeme Hewitt
Grzegorz Sarek
Sarah L Maslen
[...]
Svend Kjaer
John A Tainer
Mark Skehel
Michael Groll
Simon Boulton

Molecular Cell

Published 17 November 2016

Crick labs/ facilities

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FANCJ suppresses microsatellite instability and lymphomagenesis independent of the Fanconi anemia pathway

Authors (5)

Kenichiro Matsuzaki
Valerie Borel
Carrie A Adelman
Detlev Schindler
Simon Boulton

Genes & Development

Published 15 December 2015

Crick labs/ facilities

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Molecular basis of telomere dysfunction in human genetic diseases

Authors (4)

Grzegorz Sarek
Paulina Marzec
Pol Margalef
Simon Boulton

Nature Structural & Molecular Biology

Published 4 November 2015

Crick labs

Simon Boulton

Full details

REC-1 and HIM-5 distribute meiotic crossovers and function redundantly in meiotic double-strand break formation in Caenorhabditis elegans

Authors (9)

George Chung
Ann M Rose
Mark IR Petalcorin
Julie S Martin
Zebulin Kessler
Luis Sanchez-Pulido
Chris P Ponting
Judith L Yanowitz
Simon Boulton

Genes & Development

Published 15 September 2015

Crick labs

Simon Boulton

Full details

Rad51 paralogs remodel pre-synaptic Rad51 filaments to stimulate homologous recombination

Authors (11)

Martin RG Taylor
Mário Špírek
Kathy R Chaurasiya
Jordan D Ward
Raffaella Carzaniga
Xiong Yu
Edward H Egelman
Lucy Collinson
David Rueda
Lumir Krejci
Simon Boulton

Cell

Published 16 July 2015

Crick labs/ facilities

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BOD1L is required to suppress deleterious resection of stressed replication forks

Authors (14)

Martin R Higgs
John J Reynolds
Alicja Winczura
Andrew N Blackford
Valerie Borel
Edward S Miller
[...]
Nicholas J Davies
Tatjana Stankovic
Simon Boulton
Wojciech Niedzwiedz
Grant S Stewart

Molecular Cell

Published 6 August 2015

Crick labs

Simon Boulton

Full details

REV7 counteracts DNA double-strand break resection and affects PARP inhibition

Authors (30)

Guotai Xu
J Ross Chapman
Inger Brandsma
Jingsong Yuan
Martin Mistrik
Peter Bouwman
[...]
Dik C van Gent
Jiri Bartek
Jos Jonkers
Piet Borst
Sven Rottenberg

Nature

Published 28 May 2015

Crick labs

Simon Boulton

Full details

Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair

Authors (12)

Raphael Ceccaldi
Jessica C Liu
Ravindra Amunugama
Ildiko Hajdu
Benjamin Primack
Mark IR Petalcorin
[...]
Panagiotis A Konstantinopoulos
Stephen J Elledge
Simon Boulton
Timur Yusufzai
Alan D D'Andrea

Nature

Published 12 February 2015

Crick labs

Simon Boulton

Full details

TRF2 recruits RTEL1 to telomeres in S phase to promote t-loop unwinding

Authors (5)

Grzegorz Sarek
Jean-Baptiste Vannier
Stephanie Panier
John H Petrini
Simon Boulton

Molecular Cell

Published 19 February 2015

Crick labs

Simon Boulton

Full details

The leukemia-associated Rho guanine nucleotide exchange factor LARG is required for efficient replication stress signaling

Authors (8)

Ryan D Beveridge
Christopher J Staples
Abhijit A Patil
Katie N Myers
Sarah Maslen
Mark Skehel
Simon Boulton
Spencer J Collis

Cell Cycle

Published 1 November 2014

Crick labs

Simon Boulton

Full details

Ccdc13 is a novel human centriolar satellite protein required for ciliogenesis and genome stability

Authors (13)

Christopher J Staples
Katie N Myers
Ryan DD Beveridge
Abhijit A Patil
Anna E Howard
Giancarlo Barone
[...]
Michael Howell
Sarah Maslen
Mark Skehel
Simon Boulton
Spencer J Collis

Journal of Cell Science

Published 1 July 2014

Crick labs/ facilities

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Metabolism of DNA secondary structures at the eukaryotic replication fork

Authors (3)

Ana María León-Ortiz
Jennifer Svendsen
Simon Boulton

DNA Repair

Published 1 July 2014

Crick labs

Simon Boulton

Full details

RTEL1: functions of a disease-associated helicase

Authors (3)

Jean-Baptiste Vannier
Grzegorz Sarek
Simon Boulton

Trends in Cell Biology

Published 1 July 2014

Crick labs

Simon Boulton

Full details

Phosphorylation-dependent PIH1D1 interactions define substrate specificity of the R2TP cochaperone complex

Authors (10)

Zuzana Hořejší
Lasse Stach
Thomas G Flower
Dhira Joshi
Helen Flynn
Mark Skehel
Nicola O'Reilly
Roksana Ogrodowicz
Stephen J Smerdon
Simon Boulton

Cell Reports

Published 18 March 2014

Crick labs/ facilities

Full details

RTEL1 inhibits trinucleotide repeat expansions and fragility

Authors (7)

Aisling Frizzell
Jennifer HG Nguyen
Mark IR Petalcorin
Katherine D Turner
Simon Boulton
Catherine H Freudenreich
Robert S Lahue

Cell Reports

Published 13 March 2014

Crick labs

Simon Boulton

Full details

Double-strand break repair: 53BP1 comes into focus

Authors (2)

Stephanie Panier
Simon Boulton

Nature Reviews Molecular Cell Biology

Published 1 January 2014

Crick labs

Simon Boulton

Full details

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Boulton lab
DSB Repair Metabolism Laboratory
: Publications

Lab content

Publications

Year published

Research topics

Publication type

Journal

Repair, reuse, recycle: The expanding role of autophagy in genome maintenance

MRE11 stability is regulated by CK2-dependent interaction with R2TP complex

Human RIF1 and protein phosphatase 1 stimulate DNA replication origin licensing but suppress origin activation

A polar and nucleotide-dependent mechanism of action for RAD51 paralogs in RAD51 filament remodeling

Mechanism and regulation of DNA-protein crosslink repair by the DNA-dependent metalloprotease SPRTN

FANCJ suppresses microsatellite instability and lymphomagenesis independent of the Fanconi anemia pathway

Molecular basis of telomere dysfunction in human genetic diseases

REC-1 and HIM-5 distribute meiotic crossovers and function redundantly in meiotic double-strand break formation in Caenorhabditis elegans

Rad51 paralogs remodel pre-synaptic Rad51 filaments to stimulate homologous recombination

BOD1L is required to suppress deleterious resection of stressed replication forks

REV7 counteracts DNA double-strand break resection and affects PARP inhibition

Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair

TRF2 recruits RTEL1 to telomeres in S phase to promote t-loop unwinding

The leukemia-associated Rho guanine nucleotide exchange factor LARG is required for efficient replication stress signaling

Ccdc13 is a novel human centriolar satellite protein required for ciliogenesis and genome stability

Metabolism of DNA secondary structures at the eukaryotic replication fork

RTEL1: functions of a disease-associated helicase

Phosphorylation-dependent PIH1D1 interactions define substrate specificity of the R2TP cochaperone complex

RTEL1 inhibits trinucleotide repeat expansions and fragility

Double-strand break repair: 53BP1 comes into focus

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Research case studies

Postdoctoral clinical fellows

Hello Brain!

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About us

Lab content

Publications

Year published

Research topics

Publication type

Journal

Publications

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