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Breadcrumb Sonia Gandhi Gandhi lab Neurodegeneration Biology Laboratory : Publications Lab contentLab contentIn this section Overview Vacancies Publications Members Dopaminergic neurons generated from human induced pluripotent stem cells. Blue stain for the nuclei and yellow stain for tyrosine hydroxylase, a dopaminergic neuron marker. Toggle to view hero caption PublicationsYear published2024 (4)2023 (9)2022 (13)2021 (12)2020 (8)2019 (2)2018 (3)2017 (1)2011 (1) Facet Year publishedResearch topicsCell Biology (52)Neurosciences (52)Stem Cells (52)Computational & Systems Biology (32)Genetics & Genomics (32)Tumour Biology (32)Chemical Biology & High Throughput (31)Genome Integrity & Repair (31)Human Biology & Physiology (30)Infectious Disease (29)Immunology (27)Signalling & Oncogenes (27)Metabolism (26)Model Organisms (26)Structural Biology & Biophysics (26)Cell Cycle & Chromosomes (25)Biochemistry & Proteomics (14)Imaging (11)Developmental Biology (10)Gene Expression (5)Synthetic Biology (3)Microfabrication & Bioengineering (2) Facet Research topicsPublication typeJournal article (53)Primary research (41)Letter (8)Method (2)Review (2) Facet Publication typeJournalThe Lancet (10)Nature Cancer (3)Cancer Cell (2)Lancet Infectious Diseases (2)Movement Disorders (2)Acta Neuropathologica (1)Acta Neuropathologica Communications (1)Brain (1)Cell Death & Disease (1)Cell Death and Differentiation (1)Cell Reports (1)Cell Reports Medicine (1)Clinical Infectious Diseases (1)Communications Biology (1)Drugs and Aging (1)eLife (1)Epilepsy and Behavior (1)FEBS Journal (1)Human Molecular Genetics (1)Lancet (1)Movement Disorders Clinical Practice (1)Nature Aging (1)Nature Biotechnology (1)Nature Chemistry (1)Nature Communications (1)Nature Machine Intelligence (1)Nature Medicine (1)Nature Neuroscience (1)npj Parkinsons Disease (1)Nucleic Acids Research (1)PLOS Biology (1)PLOS ONE (1)Science (1)Science advances (1)Science Translational Medicine (1)Scientific Reports (1)Stem Cell Research (1)The Journal of Physical Chemistry B (1)Wellcome Open Research (1) Facet Journal Publications Displaying 41 - 53 of 53Last updated : 24 April 2024 03:11 Misuse of SARS-CoV-2 testing in symptomatic health-care staff in the UK – Authors' reply Authors (8) James RM Black Chris BaileyAska PrzewrockaKrijn DijkstraSonia GandhiSteve GamblinSam BarrellCharles Swanton The Lancet Published 24 October 2020 Crick labsCharles SwantonSonia GandhiSteve GamblinFull details Opicapone efficacy and tolerability in Parkinson's disease patients reporting insufficient benefit/failure of entacapone Authors (14) P Vokurka A Barron S Sumaria L Stockford P Jarman K Bhatia[...] R WeilSonia Gandhi P Limousin P Korlipara T Foltynie Movement Disorders Clinical Practice Published 1 November 2020 Crick labsSonia GandhiFull details Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers Authors (341) Catherine F Houlihan Nina Vora Thomas Byrne Dan LewerGavin Kelly Judith Heaney[...] Andrew Hayward Richard Gilson Gavin KellyFiona Roberts Emine Hatipoglu The Lancet Published 25 July 2020 Crick labs/ facilitiesAndreas WackKaren VousdenJernej UleJames TurnerMoritz TreeckCharles SwantonAdam SaterialeErik SahaiCaetano Reis e SousaPeter RatcliffeLucia Prieto-GodinoVenizelos PapayannopoulosAnne O’GarraPaul NurseGeorge KassiotisMaximiliano GutierrezSonia GandhiSteve GamblinPeter Cherepanov Luiz Pedro CarvalhoDominique BonnetMike BlackmanRupert BealeWorldwide Influenza CentreStructural BiologyMetabolomicsHuman Embryonic Stem CellHigh Throughput ScreeningGenetic Modification ServiceFlow CytometryFermentationExperimental HistopathologyElectron MicroscopyCell ServicesBiological Research FacilityBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details Scalable and robust SARS-CoV-2 testing in an academic center Authors (81) Jim Aitken Karen Ambrose Sam BarrellRupert Beale Ganka Bineva-Todd Dhruva Biswas[...]Sophie Ward Wai Keong WongJoshua Wright Mary Wu The Crick COVID-19 Consortium Nature Biotechnology Published 1 August 2020 Crick labs/ facilitiesAndreas WackJames TurnerCharles SwantonCaetano Reis e SousaPeter RatcliffeVenizelos PapayannopoulosGeorge KassiotisSonia GandhiSteve GamblinPeter Cherepanov Rupert BealeStructural BiologyMetabolomicsHigh Throughput ScreeningGenetic Modification ServiceFermentationBiological Research FacilityAdvanced SequencingScientific computingFull details Alpha synuclein aggregation drives ferroptosis: an interplay of iron, calcium and lipid peroxidation Authors (19) Plamena R AngelovaMinee Choi Alexey V Berezhnov Mathew H Horrocks Craig D Hughes Suman De[...] Sergiy Sylantyev Evgeny V Pavlov David Klenerman Andrey Y AbramovSonia Gandhi Cell Death and Differentiation Published 1 October 2020 Crick labsSonia GandhiMike DevineFull details Beta amyloid aggregates induce sensitised TLR4 signalling causing long-term potentiation deficit and rat neuronal cell death Authors (10) Craig HughesMinee Choi Jee-Hyun Yi Seung-Chan Kim Anna Drews Peter St George-Hyslop Clare BryantSonia Gandhi Kwangwook Cho David Klenerman Communications Biology Published 18 February 2020 Crick labsSonia GandhiFull details LRRK2 deficiency induced mitochondrial Ca2+ efflux inhibition can be rescued by Na+/Ca2+/Li+ exchanger upregulation Authors (6) Marthe HR Ludtmann Marko Kostic Amy HorneSonia Gandhi Israel Sekler Andrey Y Abramov Cell Death & Disease Published 19 March 2019 Crick labsSonia GandhiFull details Picomolar concentrations of oligomeric alpha-synuclein sensitizes TLR4 to play an initiating role in Parkinson's disease pathogenesis Authors (12) Craig D HughesMinee Choi Mina Ryten Lee Hopkins Anna Drews Juan A Botía[...] Margarida Rodrigues Sarah A GaglianoSonia Gandhi Clare Bryant David Klenerman Acta Neuropathologica Published 1 January 2019 Crick labsSonia GandhiFull details Crucial role of protein oligomerization in the pathogenesis of Alzheimer's and Parkinson's diseases Authors (2)Minee ChoiSonia Gandhi FEBS Journal Published 1 October 2018 Crick labsSonia GandhiFull details A single cell high content assay detects mitochondrial dysfunction in iPSC-derived neurons with mutations in SNCA Authors (12) Daniel Little Christin Luft Olukunbi Mosaku Maëlle LorvellecZhi Yao Sébastien Paillusson[...]Sonia Gandhi Andrey Y Abramov Robin KettelerMike Devine Paul Gissen Scientific Reports Published 13 June 2018 Crick labsSonia GandhiMike DevineFull details α-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinson’s disease Authors (23) Marthe HR Ludtmann Plamena R Angelova Mathew H HorrocksMinee Choi Margarida Rodrigues Artyom Y Baev[...] Morana Jaganjac Evgeny V Pavlov David Klenerman Andrey Y AbramovSonia Gandhi Nature Communications Published 12 June 2018 Crick labsSonia GandhiMike DevineFull details Progressive motor neuron pathology and the role of astrocytes in a human stem cell model of VCP-related ALS Authors (24) Claire E Hall Zhi YaoMinee ChoiGiulia TyzackAndrea Serio Raphaelle Luisier[...] Christopher R Sibley Andras LakatosJernej UleSonia GandhiRickie Patani Cell Reports Published 30 May 2017 Crick labsJernej UleAndrea SerioRickie PataniNicholas LuscombeSonia GandhiFull details PINK1 cleavage at position A103 by the mitochondrial protease PARL Authors (12) Emma Deas Helene Plun-FavreauSonia Gandhi Howard DesmondSvend Kjaer Samantha HY Loh[...] Robert J Harvey Alexander J Whitworth L Miguel Martins Andrey Y Abramov Nicholas W Wood Human Molecular Genetics Published 1 March 2011 Crick labs/ facilitiesSonia GandhiStructural BiologyFull details Pagination First page First Previous page Previous Page 1 Page 2 Current page 3 Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Misuse of SARS-CoV-2 testing in symptomatic health-care staff in the UK – Authors' reply Authors (8) James RM Black Chris BaileyAska PrzewrockaKrijn DijkstraSonia GandhiSteve GamblinSam BarrellCharles Swanton The Lancet Published 24 October 2020 Crick labsCharles SwantonSonia GandhiSteve GamblinFull details
Opicapone efficacy and tolerability in Parkinson's disease patients reporting insufficient benefit/failure of entacapone Authors (14) P Vokurka A Barron S Sumaria L Stockford P Jarman K Bhatia[...] R WeilSonia Gandhi P Limousin P Korlipara T Foltynie Movement Disorders Clinical Practice Published 1 November 2020 Crick labsSonia GandhiFull details
Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers Authors (341) Catherine F Houlihan Nina Vora Thomas Byrne Dan LewerGavin Kelly Judith Heaney[...] Andrew Hayward Richard Gilson Gavin KellyFiona Roberts Emine Hatipoglu The Lancet Published 25 July 2020 Crick labs/ facilitiesAndreas WackKaren VousdenJernej UleJames TurnerMoritz TreeckCharles SwantonAdam SaterialeErik SahaiCaetano Reis e SousaPeter RatcliffeLucia Prieto-GodinoVenizelos PapayannopoulosAnne O’GarraPaul NurseGeorge KassiotisMaximiliano GutierrezSonia GandhiSteve GamblinPeter Cherepanov Luiz Pedro CarvalhoDominique BonnetMike BlackmanRupert BealeWorldwide Influenza CentreStructural BiologyMetabolomicsHuman Embryonic Stem CellHigh Throughput ScreeningGenetic Modification ServiceFlow CytometryFermentationExperimental HistopathologyElectron MicroscopyCell ServicesBiological Research FacilityBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details
Scalable and robust SARS-CoV-2 testing in an academic center Authors (81) Jim Aitken Karen Ambrose Sam BarrellRupert Beale Ganka Bineva-Todd Dhruva Biswas[...]Sophie Ward Wai Keong WongJoshua Wright Mary Wu The Crick COVID-19 Consortium Nature Biotechnology Published 1 August 2020 Crick labs/ facilitiesAndreas WackJames TurnerCharles SwantonCaetano Reis e SousaPeter RatcliffeVenizelos PapayannopoulosGeorge KassiotisSonia GandhiSteve GamblinPeter Cherepanov Rupert BealeStructural BiologyMetabolomicsHigh Throughput ScreeningGenetic Modification ServiceFermentationBiological Research FacilityAdvanced SequencingScientific computingFull details
Alpha synuclein aggregation drives ferroptosis: an interplay of iron, calcium and lipid peroxidation Authors (19) Plamena R AngelovaMinee Choi Alexey V Berezhnov Mathew H Horrocks Craig D Hughes Suman De[...] Sergiy Sylantyev Evgeny V Pavlov David Klenerman Andrey Y AbramovSonia Gandhi Cell Death and Differentiation Published 1 October 2020 Crick labsSonia GandhiMike DevineFull details
Beta amyloid aggregates induce sensitised TLR4 signalling causing long-term potentiation deficit and rat neuronal cell death Authors (10) Craig HughesMinee Choi Jee-Hyun Yi Seung-Chan Kim Anna Drews Peter St George-Hyslop Clare BryantSonia Gandhi Kwangwook Cho David Klenerman Communications Biology Published 18 February 2020 Crick labsSonia GandhiFull details
LRRK2 deficiency induced mitochondrial Ca2+ efflux inhibition can be rescued by Na+/Ca2+/Li+ exchanger upregulation Authors (6) Marthe HR Ludtmann Marko Kostic Amy HorneSonia Gandhi Israel Sekler Andrey Y Abramov Cell Death & Disease Published 19 March 2019 Crick labsSonia GandhiFull details
Picomolar concentrations of oligomeric alpha-synuclein sensitizes TLR4 to play an initiating role in Parkinson's disease pathogenesis Authors (12) Craig D HughesMinee Choi Mina Ryten Lee Hopkins Anna Drews Juan A Botía[...] Margarida Rodrigues Sarah A GaglianoSonia Gandhi Clare Bryant David Klenerman Acta Neuropathologica Published 1 January 2019 Crick labsSonia GandhiFull details
Crucial role of protein oligomerization in the pathogenesis of Alzheimer's and Parkinson's diseases Authors (2)Minee ChoiSonia Gandhi FEBS Journal Published 1 October 2018 Crick labsSonia GandhiFull details
A single cell high content assay detects mitochondrial dysfunction in iPSC-derived neurons with mutations in SNCA Authors (12) Daniel Little Christin Luft Olukunbi Mosaku Maëlle LorvellecZhi Yao Sébastien Paillusson[...]Sonia Gandhi Andrey Y Abramov Robin KettelerMike Devine Paul Gissen Scientific Reports Published 13 June 2018 Crick labsSonia GandhiMike DevineFull details
α-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinson’s disease Authors (23) Marthe HR Ludtmann Plamena R Angelova Mathew H HorrocksMinee Choi Margarida Rodrigues Artyom Y Baev[...] Morana Jaganjac Evgeny V Pavlov David Klenerman Andrey Y AbramovSonia Gandhi Nature Communications Published 12 June 2018 Crick labsSonia GandhiMike DevineFull details
Progressive motor neuron pathology and the role of astrocytes in a human stem cell model of VCP-related ALS Authors (24) Claire E Hall Zhi YaoMinee ChoiGiulia TyzackAndrea Serio Raphaelle Luisier[...] Christopher R Sibley Andras LakatosJernej UleSonia GandhiRickie Patani Cell Reports Published 30 May 2017 Crick labsJernej UleAndrea SerioRickie PataniNicholas LuscombeSonia GandhiFull details
PINK1 cleavage at position A103 by the mitochondrial protease PARL Authors (12) Emma Deas Helene Plun-FavreauSonia Gandhi Howard DesmondSvend Kjaer Samantha HY Loh[...] Robert J Harvey Alexander J Whitworth L Miguel Martins Andrey Y Abramov Nicholas W Wood Human Molecular Genetics Published 1 March 2011 Crick labs/ facilitiesSonia GandhiStructural BiologyFull details