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Breadcrumb Stephen West West lab DNA Recombination and Repair Laboratory : Publications Lab contentLab contentIn this section Overview Areas of interest Publications Members Vacancies Lab news Alumni Cell unable to complete the recombinational repair process shows abnormalities at cell division. Toggle to view hero caption PublicationsYear published2023 (6)2022 (4)2021 (4)2020 (3)2018 (3)2017 (6)2016 (2)2015 (3)2014 (9)2013 (5)2012 (2)2011 (3)2010 (8) Facet Year publishedResearch topicsBiochemistry & Proteomics (30)Cell Biology (30)Cell Cycle & Chromosomes (30)Genetics & Genomics (30)Genome Integrity & Repair (30)Structural Biology & Biophysics (30)Chemical Biology & High Throughput (7)Model Organisms (7)Computational & Systems Biology (5)Tumour Biology (4)Human Biology & Physiology (3)Developmental Biology (2)Imaging (2)Immunology (2)Infectious Disease (2)Metabolism (2)Signalling & Oncogenes (2) Facet Research topicsPublication typeJournal article (58)Primary research (41)Review (10)Method (4)Commentary (2)Obituary (1) Facet Publication typeJournalCell Reports (6)Molecular Cell (6)Nucleic Acids Research (4)DNA Repair (3)Methods in Enzymology (3)Nature (3)Nature Structural & Molecular Biology (3)Proceedings of the National Academy of Sciences of USA (3)Cell (2)Cold Spring Harbor Symposia on Quantitative Biology (2)Genes & Development (2)Human Molecular Genetics (2)Molecular and Cellular Biology (2)Nature Communications (2)Science (2)Advanced Science (1)Analytical Biochemistry (1)Cell Cycle (1)Cell Research (1)Cold Spring Harbor Perspectives in Biology (1)Critical Reviews in Biochemistry and Molecular Biology (1)Nature Cell Biology (1)Nature Reviews Cancer (1)Oncotarget (1)Proceedings of the National Academy of Sciences of the United States of America (1)Structure (1)Trends in Biochemical Sciences (1)Trends in Cancer (1) Facet Journal Publications Displaying 41 - 58 of 58Last updated : 29 March 2024 03:23 Coordinated actions of SLX1-SLX4 and MUS81-EME1 for Holliday junction resolution in human cells Authors (4) Haley DM Wyatt Shriparna Sarbajna Joao MatosStephen West Molecular Cell Published 24 October 2013 Crick labsStephen WestFull details Architecture and DNA recognition elements of the Fanconi anemia FANCM-FAAP24 complex Authors (7) Rachel Coulthard Andrew J Deans Paolo Swuec Maureen BowlesAlessandro CostaStephen WestNeil McDonald Structure Published 3 September 2013 Crick labsStephen WestNeil McDonaldAlessandro CostaFull details DNA-dependent SUMO modification of PARP-1 Authors (7) Nicola Zilio Chris T Williamson Sebastian EustermannRajvee Shah PunatarStephen West David Neuhaus Helle D Ulrich DNA Repair Published 1 September 2013 Crick labsStephen WestFull details Cell-cycle kinases coordinate the resolution of recombination intermediates with chromosome segregation Authors (3) Joao Matos Miguel G BlancoStephen West Cell Reports Published 11 July 2013 Crick labsStephen WestFull details Senataxin, defective in the neurodegenerative disorder ataxia with oculomotor apraxia 2, lies at the interface of transcription and the DNA damage response Authors (2) Özlem YüceStephen West Molecular and Cellular Biology Published 1 January 2013 Crick labs/ facilitiesStephen WestCell ServicesFull details Distinct roles of Mus81, Yen1, Slx1-Slx4, and Rad1 nucleases in the repair of replication-born double-strand breaks by sister chromatid exchange Authors (8) Sandra Muñoz-Galván Cristina Tous Miguel G Blanco Erin K Schwartz Kirk T EhmsenStephen West Wolf-Dietrich Heyer Andrés Aguilera Molecular and Cellular Biology Published 1 May 2012 Crick labsStephen WestFull details The DNA translocase activity of FANCM protects stalled replication forks Authors (6) Andrew N Blackford Rebekka A Schwab Jadwiga Nieminuszczy Andrew J DeansStephen West Wojciech Niedzwiedz Human Molecular Genetics Published 1 May 2012 Crick labsStephen WestFull details Regulatory control of the resolution of DNA recombination intermediates during meiosis and mitosis Authors (5) Joao Matos Miguel G Blanco Sarah MaslenMark SkehelStephen West Cell Published 30 September 2011 Crick labsStephen WestFull details DNA interstrand crosslink repair and cancer Authors (2) Andrew J DeansStephen West Nature Reviews Cancer Published 1 July 2011 Crick labsStephen WestFull details Aberrant chromosome morphology in human cells defective for Holliday junction resolution Authors (3) Thomas Wechsler Scott NewmanStephen West Nature Published 31 March 2011 Crick labsStephen WestFull details The breast cancer tumor suppressor BRCA2 promotes the specific targeting of RAD51 to single-stranded DNA Authors (7) Tina Thorslund Michael J McIlwraith Sarah A Compton Sergey Lekomtsev Mark Petronczki Jack D GriffithStephen West Nature Structural & Molecular Biology Published 1 October 2010 Crick labsStephen WestFull details InTERTpreting telomerase structure and function Authors (3) Haley DM WyattStephen West Tara L Beattie Nucleic Acids Research Published 1 September 2010 Crick labsStephen WestFull details Mechanism of Holliday junction resolution by the human GEN1 protein Authors (8) Ulrich Rass Sarah A Compton Joao Matos Martin R Singleton Stephen CY Ip Miguel G Blanco Jack D GriffithStephen West Genes & Development Published 15 July 2010 Crick labsStephen WestMartin SingletonFull details Identification of KIAA1018/FAN1, a DNA repair nuclease recruited to DNA damage by monoubiquitinated FANCD2 Authors (12) Craig MacKay Anne-Cécile Déclais Cecilia Lundin Ana Agostinho Andrew J Deans Thomas J MacArtney[...] Anton GartnerStephen West Thomas Helleday David MJ Lilley John Rouse Cell Published 9 July 2010 Crick labsStephen WestFull details Functional overlap between the structure-specific nucleases Yen1 and Mus81-Mms4 for DNA-damage repair in S. cerevisiae Authors (5) Miguel G Blanco Joao Matos Ulrich Rass Stephen CY IpStephen West DNA Repair Published 4 April 2010 Crick labsStephen WestFull details The human Holliday junction resolvase GEN1 rescues the meiotic phenotype of a Schizosaccharomyces pombe mus81 mutant Authors (3) Alexander LorenzStephen West Matthew C Whitby Nucleic Acids Research Published 1 April 2010 Crick labsStephen WestFull details RTEL-1 enforces meiotic crossover interference and homeostasis Authors (10) Jillian L Youds David G Mets Michael J McIlwraith Julie S Martin Jordan D Ward Nigel J ONeil Ann M RoseStephen West Barbara J MeyerSimon Boulton Science Published 5 March 2010 Crick labsStephen WestSimon BoultonFull details Solution structures of the two PBZ domains from human APLF and their interaction with poly(ADP-ribose) Authors (8) Sebastian Eustermann Christoph Brockmann Pawan Vinod Mehrotra Ji-Chun Yang David LoakesStephen West Ivan Ahel David Neuhaus Nature Structural & Molecular Biology Published 1 February 2010 Crick labsStephen WestFull details Pagination First page First Previous page Previous Page 1 Page 2 Current page 3 Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Coordinated actions of SLX1-SLX4 and MUS81-EME1 for Holliday junction resolution in human cells Authors (4) Haley DM Wyatt Shriparna Sarbajna Joao MatosStephen West Molecular Cell Published 24 October 2013 Crick labsStephen WestFull details
Architecture and DNA recognition elements of the Fanconi anemia FANCM-FAAP24 complex Authors (7) Rachel Coulthard Andrew J Deans Paolo Swuec Maureen BowlesAlessandro CostaStephen WestNeil McDonald Structure Published 3 September 2013 Crick labsStephen WestNeil McDonaldAlessandro CostaFull details
DNA-dependent SUMO modification of PARP-1 Authors (7) Nicola Zilio Chris T Williamson Sebastian EustermannRajvee Shah PunatarStephen West David Neuhaus Helle D Ulrich DNA Repair Published 1 September 2013 Crick labsStephen WestFull details
Cell-cycle kinases coordinate the resolution of recombination intermediates with chromosome segregation Authors (3) Joao Matos Miguel G BlancoStephen West Cell Reports Published 11 July 2013 Crick labsStephen WestFull details
Senataxin, defective in the neurodegenerative disorder ataxia with oculomotor apraxia 2, lies at the interface of transcription and the DNA damage response Authors (2) Özlem YüceStephen West Molecular and Cellular Biology Published 1 January 2013 Crick labs/ facilitiesStephen WestCell ServicesFull details
Distinct roles of Mus81, Yen1, Slx1-Slx4, and Rad1 nucleases in the repair of replication-born double-strand breaks by sister chromatid exchange Authors (8) Sandra Muñoz-Galván Cristina Tous Miguel G Blanco Erin K Schwartz Kirk T EhmsenStephen West Wolf-Dietrich Heyer Andrés Aguilera Molecular and Cellular Biology Published 1 May 2012 Crick labsStephen WestFull details
The DNA translocase activity of FANCM protects stalled replication forks Authors (6) Andrew N Blackford Rebekka A Schwab Jadwiga Nieminuszczy Andrew J DeansStephen West Wojciech Niedzwiedz Human Molecular Genetics Published 1 May 2012 Crick labsStephen WestFull details
Regulatory control of the resolution of DNA recombination intermediates during meiosis and mitosis Authors (5) Joao Matos Miguel G Blanco Sarah MaslenMark SkehelStephen West Cell Published 30 September 2011 Crick labsStephen WestFull details
DNA interstrand crosslink repair and cancer Authors (2) Andrew J DeansStephen West Nature Reviews Cancer Published 1 July 2011 Crick labsStephen WestFull details
Aberrant chromosome morphology in human cells defective for Holliday junction resolution Authors (3) Thomas Wechsler Scott NewmanStephen West Nature Published 31 March 2011 Crick labsStephen WestFull details
The breast cancer tumor suppressor BRCA2 promotes the specific targeting of RAD51 to single-stranded DNA Authors (7) Tina Thorslund Michael J McIlwraith Sarah A Compton Sergey Lekomtsev Mark Petronczki Jack D GriffithStephen West Nature Structural & Molecular Biology Published 1 October 2010 Crick labsStephen WestFull details
InTERTpreting telomerase structure and function Authors (3) Haley DM WyattStephen West Tara L Beattie Nucleic Acids Research Published 1 September 2010 Crick labsStephen WestFull details
Mechanism of Holliday junction resolution by the human GEN1 protein Authors (8) Ulrich Rass Sarah A Compton Joao Matos Martin R Singleton Stephen CY Ip Miguel G Blanco Jack D GriffithStephen West Genes & Development Published 15 July 2010 Crick labsStephen WestMartin SingletonFull details
Identification of KIAA1018/FAN1, a DNA repair nuclease recruited to DNA damage by monoubiquitinated FANCD2 Authors (12) Craig MacKay Anne-Cécile Déclais Cecilia Lundin Ana Agostinho Andrew J Deans Thomas J MacArtney[...] Anton GartnerStephen West Thomas Helleday David MJ Lilley John Rouse Cell Published 9 July 2010 Crick labsStephen WestFull details
Functional overlap between the structure-specific nucleases Yen1 and Mus81-Mms4 for DNA-damage repair in S. cerevisiae Authors (5) Miguel G Blanco Joao Matos Ulrich Rass Stephen CY IpStephen West DNA Repair Published 4 April 2010 Crick labsStephen WestFull details
The human Holliday junction resolvase GEN1 rescues the meiotic phenotype of a Schizosaccharomyces pombe mus81 mutant Authors (3) Alexander LorenzStephen West Matthew C Whitby Nucleic Acids Research Published 1 April 2010 Crick labsStephen WestFull details
RTEL-1 enforces meiotic crossover interference and homeostasis Authors (10) Jillian L Youds David G Mets Michael J McIlwraith Julie S Martin Jordan D Ward Nigel J ONeil Ann M RoseStephen West Barbara J MeyerSimon Boulton Science Published 5 March 2010 Crick labsStephen WestSimon BoultonFull details
Solution structures of the two PBZ domains from human APLF and their interaction with poly(ADP-ribose) Authors (8) Sebastian Eustermann Christoph Brockmann Pawan Vinod Mehrotra Ji-Chun Yang David LoakesStephen West Ivan Ahel David Neuhaus Nature Structural & Molecular Biology Published 1 February 2010 Crick labsStephen WestFull details