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Breadcrumb Steve Gamblin Gamblin lab Structural Biology of Disease Processes Laboratory : Publications Lab contentLab contentIn this section Overview Areas of interest Publications Members Vacancies Structures of proteins investigated in the Gamblin lab: AMPK, PRC2 and influenza hemagglutinin (left to right). Toggle to view hero caption PublicationsYear published2016 (1) Facet Year publishedResearch topicsCell Cycle & Chromosomes (1)Infectious Disease (1)Metabolism (1)Structural Biology & Biophysics (1) Facet Research topicsPublication typeJournal article (1)Primary research (1) Facet Publication typeJournal (-)Journal of Medicinal Chemistry (1) Facet Journal Publications Displaying 1 - 1 of 1Last updated : 25 April 2024 02:27 Identification of (R)-N-((4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-2-methyl-1-(1-(1-(2,2,2-trifluoroethyl)piperidin-4-yl)ethyl)-1H-indole-3-carboxamide (CPI-1205), a potent and selective inhibitor of histone methyltransferase EZH2, suitabl Authors (25) Rishi G Vaswani Victor S Gehling Les A Dakin Andrew S Cook Christopher G Nasveschuk Martin Duplessis[...]Ying ZhangNeil JustinShuyang ChenJon WilsonSteve Gamblin Journal of Medicinal Chemistry Published 10 November 2016 Crick labsSteve GamblinFull details Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Identification of (R)-N-((4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-2-methyl-1-(1-(1-(2,2,2-trifluoroethyl)piperidin-4-yl)ethyl)-1H-indole-3-carboxamide (CPI-1205), a potent and selective inhibitor of histone methyltransferase EZH2, suitabl Authors (25) Rishi G Vaswani Victor S Gehling Les A Dakin Andrew S Cook Christopher G Nasveschuk Martin Duplessis[...]Ying ZhangNeil JustinShuyang ChenJon WilsonSteve Gamblin Journal of Medicinal Chemistry Published 10 November 2016 Crick labsSteve GamblinFull details