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Breadcrumb Steve Gamblin Gamblin lab Structural Biology of Disease Processes Laboratory : Publications Lab contentLab contentIn this section Overview Areas of interest Publications Members Vacancies Structures of proteins investigated in the Gamblin lab: AMPK, PRC2 and influenza hemagglutinin (left to right). Toggle to view hero caption PublicationsYear published (-)2022 (10) Facet Year publishedResearch topicsCell Cycle & Chromosomes (10)Infectious Disease (10)Metabolism (10)Structural Biology & Biophysics (10)Cell Biology (8)Model Organisms (8)Chemical Biology & High Throughput (7)Computational & Systems Biology (7)Genetics & Genomics (7)Immunology (7)Genome Integrity & Repair (6)Human Biology & Physiology (6)Neurosciences (6)Stem Cells (6)Tumour Biology (6)Signalling & Oncogenes (5)Biochemistry & Proteomics (3)Imaging (3)Developmental Biology (2) Facet Research topicsPublication typeJournal article (10)Primary research (7)Commentary (1)Letter (1)Method (1) Facet Publication typeJournalThe Lancet (4)Cell Reports Medicine (1)Methods in Molecular Biology (1)Nature Communications (1)Proceedings of the National Academy of Sciences of USA (1)Science Translational Medicine (1)Structure (1) Facet Journal Publications Displaying 1 - 10 of 10Last updated : 19 April 2024 02:47 Hold your horses: The receptor-binding domains of SARS-CoV-2, SARS-CoV, and hCoV-NL63 bind equine ACE2 Authors (2) Philipp NawrathAntoni Wrobel Structure Published 6 October 2022 Crick labsSteve GamblinFull details WHO's therapeutics and COVID-19 living guideline on mAbs needs to be reassessed Authors (19)Mary WuEdward Carr Ruth HarveyHarriet MearsSvend Kjaer Hermaleigh Townsley[...] Bryan WilliamsSonia GandhiCharles Swanton Emma C WallDavid LV Bauer The Lancet Published 17 December 2022 Crick labs/ facilitiesCharles SwantonNicola LewisSonia GandhiSteve GamblinRupert BealeDavid LV BauerWorldwide Influenza CentreStructural BiologyHigh Throughput ScreeningFull details Functional immune responses against SARS-CoV-2 variants of concern after fourth COVID-19 vaccine dose or infection in patients with blood cancer Authors (64)Annika FendlerScott ShepherdLewis AuMary Wu Ruth HarveyKatalin Wilkinson[...] Emma Nicholson Susanna WalkerRobert Wilkinson James LarkinSamra Turajlic Cell Reports Medicine Published 18 October 2022 Crick labs/ facilitiesRobert J WilkinsonSamra TurajlicCharles SwantonGeorge KassiotisSonia GandhiSteve GamblinRupert BealeDavid LV BauerWorldwide Influenza CentreStructural BiologyMetabolomicsHigh Throughput ScreeningScientific computingFull details Reversible structural changes in the influenza hemagglutinin precursor at membrane fusion pH Authors (7)Eva Garcia MoroJie ZhangLesley Calder Nick R BrownSteve Gamblin John J SkehelPeter Rosenthal Proceedings of the National Academy of Sciences of USA Published 16 August 2022 Crick labs/ facilitiesPeter RosenthalSteve GamblinStructural BiologyScientific computingFull details SARS-CoV-2 S2-targeted vaccination elicits broadly neutralizing antibodies Authors (21)Kevin NgNikhil FaulknerKatja FinsterbuschMary Wu Ruth HarveySaira Hussain[...]Michael Howell Hisashi AraseAndreas WackDavid LV BauerGeorge Kassiotis Science Translational Medicine Published 27 July 2022 Crick labs/ facilitiesAndreas WackCharles SwantonNicola LewisGeorge KassiotisSonia GandhiSteve GamblinPeter Cherepanov Rupert BealeDavid LV BauerWorldwide Influenza CentreStructural BiologyHigh Throughput ScreeningFlow CytometryCell ServicesBiological Research FacilityFull details Determination of histone methyltransferase structure by crystallography Authors (1)Jon Wilson Methods in Molecular Biology Published 23 June 2022 Crick labsSteve GamblinFull details Evolution of the SARS-CoV-2 spike protein in thehuman host Authors (9)Antoni WrobelDonald BentonChloe RoustanAnnabel BorgSaira Hussain Stephen R MartinPeter Rosenthal John J SkehelSteve Gamblin Nature Communications Published 4 March 2022 Crick labs/ facilitiesPeter RosenthalNicola LewisSteve GamblinDavid LV BauerWorldwide Influenza CentreStructural BiologyScientific computingFull details Omicron neutralising antibodies after third COVID-19 vaccine dose in patients with cancer Authors (62)Annika FendlerScott ShepherdLewis AuMary Wu Ruth Harvey Andreas M Schmitt[...] Emma Nicholson Susanna Walker James LarkinSamra Turajlic The CAPTURE consortium The Lancet Published 5 March 2022 Crick labs/ facilitiesRobert J WilkinsonSamra TurajlicCharles SwantonNicola LewisGeorge KassiotisSonia GandhiSteve GamblinRupert BealeDavid LV BauerWorldwide Influenza CentreStructural BiologyMetabolomicsHigh Throughput ScreeningBiological Research FacilityBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details Omicron neutralising antibodies after COVID-19 vaccination in haemodialysis patients Authors (19)Edward CarrMary Wu Ruth Harvey Roseanne E Billany Emma C WallGavin Kelly[...] Rachel B Jones Rona M Smith Stephen McAdoo Michelle WillicombeRupert Beale The Lancet Published 26 February 2022 Crick labs/ facilitiesCharles SwantonGitta StockingerNicola LewisGeorge KassiotisSonia GandhiSteve GamblinRupert BealeDavid LV BauerWorldwide Influenza CentreHigh Throughput ScreeningBioinformatics and BiostatisticsFull details Three-dose vaccination elicits neutralising antibodies against omicron Authors (26)Mary Wu Emma C WallEdward Carr Ruth Harvey Hermaleigh TownsleyHarriet Mears[...] Vincenzo Libri Bryan WilliamsSonia GandhiCharles SwantonDavid LV Bauer The Lancet Published 19 February 2022 Crick labs/ facilitiesCharles SwantonGitta StockingerNicola LewisGeorge KassiotisSonia GandhiSteve GamblinRupert BealeDavid LV BauerWorldwide Influenza CentreStructural BiologyHigh Throughput ScreeningBioinformatics and BiostatisticsScientific computingFull details Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Hold your horses: The receptor-binding domains of SARS-CoV-2, SARS-CoV, and hCoV-NL63 bind equine ACE2 Authors (2) Philipp NawrathAntoni Wrobel Structure Published 6 October 2022 Crick labsSteve GamblinFull details
WHO's therapeutics and COVID-19 living guideline on mAbs needs to be reassessed Authors (19)Mary WuEdward Carr Ruth HarveyHarriet MearsSvend Kjaer Hermaleigh Townsley[...] Bryan WilliamsSonia GandhiCharles Swanton Emma C WallDavid LV Bauer The Lancet Published 17 December 2022 Crick labs/ facilitiesCharles SwantonNicola LewisSonia GandhiSteve GamblinRupert BealeDavid LV BauerWorldwide Influenza CentreStructural BiologyHigh Throughput ScreeningFull details
Functional immune responses against SARS-CoV-2 variants of concern after fourth COVID-19 vaccine dose or infection in patients with blood cancer Authors (64)Annika FendlerScott ShepherdLewis AuMary Wu Ruth HarveyKatalin Wilkinson[...] Emma Nicholson Susanna WalkerRobert Wilkinson James LarkinSamra Turajlic Cell Reports Medicine Published 18 October 2022 Crick labs/ facilitiesRobert J WilkinsonSamra TurajlicCharles SwantonGeorge KassiotisSonia GandhiSteve GamblinRupert BealeDavid LV BauerWorldwide Influenza CentreStructural BiologyMetabolomicsHigh Throughput ScreeningScientific computingFull details
Reversible structural changes in the influenza hemagglutinin precursor at membrane fusion pH Authors (7)Eva Garcia MoroJie ZhangLesley Calder Nick R BrownSteve Gamblin John J SkehelPeter Rosenthal Proceedings of the National Academy of Sciences of USA Published 16 August 2022 Crick labs/ facilitiesPeter RosenthalSteve GamblinStructural BiologyScientific computingFull details
SARS-CoV-2 S2-targeted vaccination elicits broadly neutralizing antibodies Authors (21)Kevin NgNikhil FaulknerKatja FinsterbuschMary Wu Ruth HarveySaira Hussain[...]Michael Howell Hisashi AraseAndreas WackDavid LV BauerGeorge Kassiotis Science Translational Medicine Published 27 July 2022 Crick labs/ facilitiesAndreas WackCharles SwantonNicola LewisGeorge KassiotisSonia GandhiSteve GamblinPeter Cherepanov Rupert BealeDavid LV BauerWorldwide Influenza CentreStructural BiologyHigh Throughput ScreeningFlow CytometryCell ServicesBiological Research FacilityFull details
Determination of histone methyltransferase structure by crystallography Authors (1)Jon Wilson Methods in Molecular Biology Published 23 June 2022 Crick labsSteve GamblinFull details
Evolution of the SARS-CoV-2 spike protein in thehuman host Authors (9)Antoni WrobelDonald BentonChloe RoustanAnnabel BorgSaira Hussain Stephen R MartinPeter Rosenthal John J SkehelSteve Gamblin Nature Communications Published 4 March 2022 Crick labs/ facilitiesPeter RosenthalNicola LewisSteve GamblinDavid LV BauerWorldwide Influenza CentreStructural BiologyScientific computingFull details
Omicron neutralising antibodies after third COVID-19 vaccine dose in patients with cancer Authors (62)Annika FendlerScott ShepherdLewis AuMary Wu Ruth Harvey Andreas M Schmitt[...] Emma Nicholson Susanna Walker James LarkinSamra Turajlic The CAPTURE consortium The Lancet Published 5 March 2022 Crick labs/ facilitiesRobert J WilkinsonSamra TurajlicCharles SwantonNicola LewisGeorge KassiotisSonia GandhiSteve GamblinRupert BealeDavid LV BauerWorldwide Influenza CentreStructural BiologyMetabolomicsHigh Throughput ScreeningBiological Research FacilityBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details
Omicron neutralising antibodies after COVID-19 vaccination in haemodialysis patients Authors (19)Edward CarrMary Wu Ruth Harvey Roseanne E Billany Emma C WallGavin Kelly[...] Rachel B Jones Rona M Smith Stephen McAdoo Michelle WillicombeRupert Beale The Lancet Published 26 February 2022 Crick labs/ facilitiesCharles SwantonGitta StockingerNicola LewisGeorge KassiotisSonia GandhiSteve GamblinRupert BealeDavid LV BauerWorldwide Influenza CentreHigh Throughput ScreeningBioinformatics and BiostatisticsFull details
Three-dose vaccination elicits neutralising antibodies against omicron Authors (26)Mary Wu Emma C WallEdward Carr Ruth Harvey Hermaleigh TownsleyHarriet Mears[...] Vincenzo Libri Bryan WilliamsSonia GandhiCharles SwantonDavid LV Bauer The Lancet Published 19 February 2022 Crick labs/ facilitiesCharles SwantonGitta StockingerNicola LewisGeorge KassiotisSonia GandhiSteve GamblinRupert BealeDavid LV BauerWorldwide Influenza CentreStructural BiologyHigh Throughput ScreeningBioinformatics and BiostatisticsScientific computingFull details