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Breadcrumb Vassilis Pachnis Pachnis lab Development and Homeostasis of the Nervous System Laboratory : Publications Lab contentLab contentIn this section Overview Vacancies Areas of interest Publications Members A group of neurons (blue), glial cells (green) and immune cells (red) within the gut wall. Image captured at the Crick by PhD student Ana Oliveira. Toggle to view hero caption PublicationsYear published2023 (3)2022 (5)2021 (1)2020 (4)2019 (2)2018 (2)2017 (4)2016 (8)2015 (7)2014 (5)2013 (2)2012 (5)2011 (5)2010 (2) Facet Year publishedResearch topicsDevelopmental Biology (35)Genetics & Genomics (35)Model Organisms (35)Neurosciences (35)Stem Cells (35)Chemical Biology & High Throughput (6)Computational & Systems Biology (6)Genome Integrity & Repair (6)Tumour Biology (6)Imaging (4)Human Biology & Physiology (3)Immunology (3)Cell Biology (2)Signalling & Oncogenes (2)Gene Expression (1) Facet Research topicsPublication typeJournal article (55)Primary research (38)Review (12)Commentary (3)Method (2) Facet Publication typeJournalDevelopmental Biology (5)Nature (4)BMC Biology (3)Cerebral Cortex (3)Journal of Clinical Investigation (3)Cell Reports (2)Gastroenterology (2)Glia (2)Nature Communications (2)Science (2)Stem Cells (2)American Journal of Human Genetics (1)Annals of the Rheumatic Diseases (1)Cell Cycle (1)Cell Stem Cell (1)Current Opinion in Immunology (1)Current Opinion in Pharmacology (1)Development (1)eLife (1)Frontiers in Molecular Neuroscience (1)Gut Microbes (1)Immunity (1)Journal of Allergy and Clinical Immunology (1)Journal of Experimental Neuroscience (1)Journal of Immunology (1)Journal of Neuroscience (1)Journal of Visualized Experiments (1)Nature Immunology (1)Nature Protocols (1)Neuron (1)PLOS Genetics (1)PLOS ONE (1)Proceedings of the National Academy of Sciences of the United States of America (1)Proceedings of the National Academy of Sciences of USA (1)Science advances (1)Science Signaling (1) Facet Journal Publications Displaying 1 - 20 of 55Last updated : 11 December 2023 03:44 A branching model of lineage differentiation underpinning the neurogenic potential of enteric glia Authors (15) Anna LaddachSong Hui ChngReena LasradoFranze ProgatzkyMichael Shapiro Alek Erickson[...] Jens Kleinjung Stefan BoeingSila Ultanir Igor AdameykoVassilis Pachnis Nature Communications Published 22 September 2023 Crick labs/ facilitiesSila UltanirVassilis PachnisBioinformatics and BiostatisticsFlow CytometryBiological Research FacilityAdvanced SequencingFull details Boundaries and integration between microbiota, the nervous system, and immunity Authors (3) Andrew J MacphersonVassilis Pachnis Marco Prinz Immunity Published 8 August 2023 Crick labsVassilis PachnisFull details IFN-γ–dependent interactions between tissue-intrinsic γδ T cells and tissue-infiltrating CD8 T cells limit allergic contact dermatitis Authors (15)Miguel Munoz-Ruiz Miriam LlorianRocco D'Antuono Anna Pavlova Anna Maria MavrigiannakiDuncan McKenzie[...] Daniel Davies Mariam Jamal-Hanjani Anett Jandke Dmitry S UshakovAdrian Hayday Journal of Allergy and Clinical Immunology Published 1 December 2023 Crick labs/ facilitiesVassilis PachnisAdrian HaydayLight MicroscopyBioinformatics and BiostatisticsFull details MTG8 interacts with LHX6 to specify cortical interneuron subtype identity Authors (11) Zeinab Asgarian Marcio Guiomar Oliveira Agata Stryjewska Ioannis Maragkos Anna Noren Rubin Lorenza MagnoVassilis Pachnis Mohammadmersad Ghorbani Scott Wayne Hiebert Myrto Denaxa Nicoletta Kessaris Nature Communications Published 5 September 2022 Crick labsVassilis PachnisFull details Molecular profiling of enteric nervous system cell lineages Authors (10)Yuuki ObataAlvaro Castano MedinaTodd FallesenAna Bon Frauches Oliveira Stefan BoeingAlmaz HuseynovaSarah MccallumReena LasradoTiffany HeanueVassilis Pachnis Nature Protocols Published 1 August 2022 Crick labs/ facilitiesSila UltanirVassilis PachnisLight MicroscopyBioinformatics and BiostatisticsScientific computingFull details Multiple roles of Ret signalling during enteric neurogenesis Authors (5) Dipa Natarajan Conor McCann Justine DattaniVassilis Pachnis Nikhil Thapar Frontiers in Molecular Neuroscience Published 27 May 2022 Crick labs/ facilitiesVassilis PachnisFlow CytometryFull details The role of enteric glia in intestinal immunity Authors (2)Franze ProgatzkyVassilis Pachnis Current Opinion in Immunology Published 1 August 2022 Crick labsVassilis PachnisFull details Enteric glia bring fresh WNT to the intestinal stem cell niche Authors (2)Franze ProgatzkyVassilis Pachnis Cell Stem Cell Published 6 January 2022 Crick labsVassilis PachnisFull details Regulation of intestinal immunity and tissue repair by enteric glia Authors (18)Franze ProgatzkyMichael ShapiroSong Hui Chng Bethania Garcia-CassaniCajsa Classon Selin Sevgi[...] Lewis J Entwistle Alejandro Suárez-Bonnet Mark WilsonBrigitta StockingerVassilis Pachnis Nature Published 20 October 2021 Crick labs/ facilitiesGitta StockingerVassilis PachnisExperimental HistopathologyBioinformatics and BiostatisticsFlow CytometryBiological Research FacilityAdvanced SequencingFull details Enteric glia as a source of neural progenitors in adult zebrafish Authors (13)Sarah MccallumYuuki Obata Evangelia Fourli Stefan BoeingChris PeddieQiling Xu[...]Lucy Collinson David Wilkinson Carmen PinVassilis PachnisTiffany Heanue eLife Published 27 August 2020 Crick labs/ facilitiesDavid WilkinsonVassilis PachnisElectron MicroscopyBioinformatics and BiostatisticsLight MicroscopyFlow CytometryBiological Research FacilityAdvanced SequencingFull details Linking neurons to immunity: Lessons from Hydra Authors (2)Yuuki ObataVassilis Pachnis Proceedings of the National Academy of Sciences of USA Published 18 August 2020 Crick labsVassilis PachnisFull details Enteric nervous system: lessons from neurogenesis for reverse engineering and disease modelling and treatment Authors (2)Song Hui ChngVassilis Pachnis Current Opinion in Pharmacology Published 30 March 2020 Crick labsVassilis PachnisFull details Neuronal programming by microbiota regulates intestinal physiology Authors (18)Yuuki ObataAlvaro Castano Medina Stefan BoeingAna Bon Frauches Oliveira Candice FungTodd Fallesen[...] Pieter Vanden Berghe Andrew J MurrayBrigitta Stockinger Andrew J MacphersonVassilis Pachnis Nature Published 13 February 2020 Crick labs/ facilitiesGitta StockingerVassilis PachnisLight MicroscopyBioinformatics and BiostatisticsAdvanced SequencingFull details Transplantation of chemogenetically engineered cortical interneuron progenitors into early postnatal mouse brains Authors (4) Myrto Denaxa Guilherme Neves Juan BurroneVassilis Pachnis Journal of Visualized Experiments Published 26 August 2019 Crick labsVassilis PachnisFull details Structurally defined signaling in neuro-glia units in the enteric nervous system Authors (8) Werend Boesmans Marlene M Hao Candice Fung Zhiling Li Chris Van den Haute Jan TackVassilis Pachnis Pieter Vanden Berghe Glia Published 1 June 2019 Crick labsVassilis PachnisFull details Homeostatic regulation of interneuron apoptosis during cortical development Authors (4) Myrto Denaxa Guilherme Neves Juan BurroneVassilis Pachnis Journal of Experimental Neuroscience Published 5 July 2018 Crick labsVassilis PachnisFull details Modulation of apoptosis controls inhibitory interneuron number in the cortex Authors (7) Myrto Denaxa Guilherme Neves Adam Rabinowitz Sarah Kemlo Petros Liodis Juan BurroneVassilis Pachnis Cell Reports Published 13 February 2018 Crick labs/ facilitiesVassilis PachnisBioinformatics and BiostatisticsFull details Transcription and signaling regulators in developing neuronal subtypes of mouse and human enteric nervous system Authors (9) Fatima Memic Viktoria Knoflach Khomgrit Morarach Rebecca Sadler Catia Laranjeira Jens Hjerling-Leffler Erik SundströmVassilis Pachnis Ulrika Marklund Gastroenterology Published 12 October 2017 Crick labsVassilis PachnisFull details Lhx6-positive GABA-releasing neurons of the zona incerta promote sleep Authors (15) Kai Liu Juhyun Kim Dong Won Kim Yi Stephanie Zhang Hechen Bao Myrto Denaxa[...]Vassilis Pachnis Samer Hattar Juan Song Solange P Brown Seth Blackshaw Nature Published 31 August 2017 Crick labsVassilis PachnisFull details Lineage-dependent spatial and functional organization of the mammalian enteric nervous system Authors (12)Reena Lasrado Werend Boesmans Jens Kleinjung Carmen PinDonald Bell Leena Bhaw[...] Hui Zong Liqun Luo Hans Clevers Pieter Vanden BergheVassilis Pachnis Science Published 19 May 2017 Crick labs/ facilitiesVassilis PachnisLight MicroscopyFlow CytometryBiological Research FacilityAdvanced SequencingFull details Pagination Current page 1 Page 2 Page 3 Next page Next Last page Last Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
A branching model of lineage differentiation underpinning the neurogenic potential of enteric glia Authors (15) Anna LaddachSong Hui ChngReena LasradoFranze ProgatzkyMichael Shapiro Alek Erickson[...] Jens Kleinjung Stefan BoeingSila Ultanir Igor AdameykoVassilis Pachnis Nature Communications Published 22 September 2023 Crick labs/ facilitiesSila UltanirVassilis PachnisBioinformatics and BiostatisticsFlow CytometryBiological Research FacilityAdvanced SequencingFull details
Boundaries and integration between microbiota, the nervous system, and immunity Authors (3) Andrew J MacphersonVassilis Pachnis Marco Prinz Immunity Published 8 August 2023 Crick labsVassilis PachnisFull details
IFN-γ–dependent interactions between tissue-intrinsic γδ T cells and tissue-infiltrating CD8 T cells limit allergic contact dermatitis Authors (15)Miguel Munoz-Ruiz Miriam LlorianRocco D'Antuono Anna Pavlova Anna Maria MavrigiannakiDuncan McKenzie[...] Daniel Davies Mariam Jamal-Hanjani Anett Jandke Dmitry S UshakovAdrian Hayday Journal of Allergy and Clinical Immunology Published 1 December 2023 Crick labs/ facilitiesVassilis PachnisAdrian HaydayLight MicroscopyBioinformatics and BiostatisticsFull details
MTG8 interacts with LHX6 to specify cortical interneuron subtype identity Authors (11) Zeinab Asgarian Marcio Guiomar Oliveira Agata Stryjewska Ioannis Maragkos Anna Noren Rubin Lorenza MagnoVassilis Pachnis Mohammadmersad Ghorbani Scott Wayne Hiebert Myrto Denaxa Nicoletta Kessaris Nature Communications Published 5 September 2022 Crick labsVassilis PachnisFull details
Molecular profiling of enteric nervous system cell lineages Authors (10)Yuuki ObataAlvaro Castano MedinaTodd FallesenAna Bon Frauches Oliveira Stefan BoeingAlmaz HuseynovaSarah MccallumReena LasradoTiffany HeanueVassilis Pachnis Nature Protocols Published 1 August 2022 Crick labs/ facilitiesSila UltanirVassilis PachnisLight MicroscopyBioinformatics and BiostatisticsScientific computingFull details
Multiple roles of Ret signalling during enteric neurogenesis Authors (5) Dipa Natarajan Conor McCann Justine DattaniVassilis Pachnis Nikhil Thapar Frontiers in Molecular Neuroscience Published 27 May 2022 Crick labs/ facilitiesVassilis PachnisFlow CytometryFull details
The role of enteric glia in intestinal immunity Authors (2)Franze ProgatzkyVassilis Pachnis Current Opinion in Immunology Published 1 August 2022 Crick labsVassilis PachnisFull details
Enteric glia bring fresh WNT to the intestinal stem cell niche Authors (2)Franze ProgatzkyVassilis Pachnis Cell Stem Cell Published 6 January 2022 Crick labsVassilis PachnisFull details
Regulation of intestinal immunity and tissue repair by enteric glia Authors (18)Franze ProgatzkyMichael ShapiroSong Hui Chng Bethania Garcia-CassaniCajsa Classon Selin Sevgi[...] Lewis J Entwistle Alejandro Suárez-Bonnet Mark WilsonBrigitta StockingerVassilis Pachnis Nature Published 20 October 2021 Crick labs/ facilitiesGitta StockingerVassilis PachnisExperimental HistopathologyBioinformatics and BiostatisticsFlow CytometryBiological Research FacilityAdvanced SequencingFull details
Enteric glia as a source of neural progenitors in adult zebrafish Authors (13)Sarah MccallumYuuki Obata Evangelia Fourli Stefan BoeingChris PeddieQiling Xu[...]Lucy Collinson David Wilkinson Carmen PinVassilis PachnisTiffany Heanue eLife Published 27 August 2020 Crick labs/ facilitiesDavid WilkinsonVassilis PachnisElectron MicroscopyBioinformatics and BiostatisticsLight MicroscopyFlow CytometryBiological Research FacilityAdvanced SequencingFull details
Linking neurons to immunity: Lessons from Hydra Authors (2)Yuuki ObataVassilis Pachnis Proceedings of the National Academy of Sciences of USA Published 18 August 2020 Crick labsVassilis PachnisFull details
Enteric nervous system: lessons from neurogenesis for reverse engineering and disease modelling and treatment Authors (2)Song Hui ChngVassilis Pachnis Current Opinion in Pharmacology Published 30 March 2020 Crick labsVassilis PachnisFull details
Neuronal programming by microbiota regulates intestinal physiology Authors (18)Yuuki ObataAlvaro Castano Medina Stefan BoeingAna Bon Frauches Oliveira Candice FungTodd Fallesen[...] Pieter Vanden Berghe Andrew J MurrayBrigitta Stockinger Andrew J MacphersonVassilis Pachnis Nature Published 13 February 2020 Crick labs/ facilitiesGitta StockingerVassilis PachnisLight MicroscopyBioinformatics and BiostatisticsAdvanced SequencingFull details
Transplantation of chemogenetically engineered cortical interneuron progenitors into early postnatal mouse brains Authors (4) Myrto Denaxa Guilherme Neves Juan BurroneVassilis Pachnis Journal of Visualized Experiments Published 26 August 2019 Crick labsVassilis PachnisFull details
Structurally defined signaling in neuro-glia units in the enteric nervous system Authors (8) Werend Boesmans Marlene M Hao Candice Fung Zhiling Li Chris Van den Haute Jan TackVassilis Pachnis Pieter Vanden Berghe Glia Published 1 June 2019 Crick labsVassilis PachnisFull details
Homeostatic regulation of interneuron apoptosis during cortical development Authors (4) Myrto Denaxa Guilherme Neves Juan BurroneVassilis Pachnis Journal of Experimental Neuroscience Published 5 July 2018 Crick labsVassilis PachnisFull details
Modulation of apoptosis controls inhibitory interneuron number in the cortex Authors (7) Myrto Denaxa Guilherme Neves Adam Rabinowitz Sarah Kemlo Petros Liodis Juan BurroneVassilis Pachnis Cell Reports Published 13 February 2018 Crick labs/ facilitiesVassilis PachnisBioinformatics and BiostatisticsFull details
Transcription and signaling regulators in developing neuronal subtypes of mouse and human enteric nervous system Authors (9) Fatima Memic Viktoria Knoflach Khomgrit Morarach Rebecca Sadler Catia Laranjeira Jens Hjerling-Leffler Erik SundströmVassilis Pachnis Ulrika Marklund Gastroenterology Published 12 October 2017 Crick labsVassilis PachnisFull details
Lhx6-positive GABA-releasing neurons of the zona incerta promote sleep Authors (15) Kai Liu Juhyun Kim Dong Won Kim Yi Stephanie Zhang Hechen Bao Myrto Denaxa[...]Vassilis Pachnis Samer Hattar Juan Song Solange P Brown Seth Blackshaw Nature Published 31 August 2017 Crick labsVassilis PachnisFull details
Lineage-dependent spatial and functional organization of the mammalian enteric nervous system Authors (12)Reena Lasrado Werend Boesmans Jens Kleinjung Carmen PinDonald Bell Leena Bhaw[...] Hui Zong Liqun Luo Hans Clevers Pieter Vanden BergheVassilis Pachnis Science Published 19 May 2017 Crick labs/ facilitiesVassilis PachnisLight MicroscopyFlow CytometryBiological Research FacilityAdvanced SequencingFull details