Tybulewicz lab
Immune Cell Biology Laboratory & Down Syndrome Laboratory
: Publications

Publications

Displaying 61 - 80 of 91

Last updated : 19 April 2024 03:31

A key regulatory role for Vav1 in controlling lipopolysaccharide endotoxemia via macrophage-derived IL-6

Authors (9)

Stefanie Zenker
Julia Panteleev-Ivlev
Stefan Wirtz
Tadamitsu Kishimoto
Maximilian J Waldner
Olga Ksionda
Victor Tybulewicz
Markus F Neurath
Imke Atreya

Journal of Immunology

Published 14 February 2014

Crick labs

Victor Tybulewicz

Full details

Automatic structural parcellation of mouse brain MRI using multi-atlas label fusion

Authors (11)

Da Ma
Manuel J Cardoso
Marc Modat
Nick Powell
Jack Wells
Holly Holmes
Frances Wiseman
Victor Tybulewicz
Elizabeth Fisher
Mark F Lythgoe
Sébastien Ourselin

PLOS ONE

Published 1 January 2014

Crick labs

Victor Tybulewicz

Full details

Phosphorylation of the adaptor ASC acts as a molecular switch that controls the formation of speck-like aggregates and inflammasome activity

Authors (10)

Hideki Hara
Kohsuke Tsuchiya
Ikuo Kawamura
Rendong Fang
Eduardo Hernandez-Cuellar
Yanna Shen
Junichiro Mizuguchi
Edina Schweighoffer
Victor Tybulewicz
Masao Mitsuyama

Nature Immunology

Published 3 November 2013

Crick labs

Victor Tybulewicz

Full details

Protein profiles in Tc1 mice implicate novel pathway perturbations in the Down syndrome brain

Authors (7)

Md Mahiuddin Ahmed
A Ranjitha Dhanasekaran
Suhong Tong
Frances K Wiseman
Elizabeth MC Fisher
Victor Tybulewicz
Katheleen J Gardiner

Human Molecular Genetics

Published 24 January 2013

Crick labs

Victor Tybulewicz

Full details

Alterations to dendritic spine morphology, but not dendrite patterning, of cortical projection neurons in Tc1 and Ts1Rhr mouse models of Down Syndrome

Authors (8)

Matilda A Haas
Donald Bell
Amy Slender
Eva Lana-Elola
Sheona Watson-Scales
Elizabeth MC Fisher
Victor Tybulewicz
Francois Guillemot

PLOS ONE

Published 1 January 2013

Crick labs/ facilities

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Massively parallel sequencing reveals the complex structure of an irradiated human chromosome on a mouse background in the Tc1 model of Down syndrome

Authors (22)

Susan M Gribble
Frances K Wiseman
Stephen Clayton
Elena Prigmore
Elizabeth Langley
Fengtang Yang
[...]
Ruby Banerjee
Kai Rothkamm
Victor Tybulewicz
Elizabeth MC Fisher
Nigel P Carter

PLOS ONE

Published 1 January 2013

Crick labs

Victor Tybulewicz

Full details

The BAFF receptor transduces survival signals by co-opting the B cell receptor signaling pathway

Authors (7)

Edina Schweighoffer
Lesley Vanes
Josquin Nys
Doreen Cantrell
Scott McCleary
Nicholas Smithers
Victor Tybulewicz

Immunity

Published 1 January 2013

Crick labs

Victor Tybulewicz

Full details

Overexpression of the Hspa13 (Stch) gene reduces prion disease incubation time in mice

Authors (14)

Julia Grizenkova
Shaheen Akhtar
Holger Hummerich
Andrew Tomlinson
Emmanuel A Asante
Adam Wenborn
[...]
Elizabeth MC Fisher
Victor Tybulewicz
Sebastian Brandner
John Collinge
Sarah E Lloyd

Proceedings of the National Academy of Sciences of the United States of America

Published 6 August 2012

Crick labs

Victor Tybulewicz

Full details

Altered regulation of tau phosphorylation in a mouse model of down syndrome aging

Authors (9)

O Sheppard
F Plattner
A Rubin
A Slender
JM Linehan
S Brandner
Victor Tybulewicz
EMC Fisher
FK Wiseman

Neurobiology of Aging

Published 1 January 2012

Crick labs

Victor Tybulewicz

Full details

CLEC-2 and Syk in the megakaryocytic/platelet lineage are essential for development

Authors (16)

Brenda A Finney
Edina Schweighoffer
Leyre Navarro-Núñez
Cecile Bénézech
Francesca Barone
Craig E Hughes
[...]
Gerard B Nash
Nicholas Smithers
Caetano Reis e Sousa
Victor Tybulewicz
Steve P Watson

Blood

Published 1 January 2012

Crick labs

Full details

Genomically humanized mice: technologies and promises

Authors (5)

Anny Devoy
Rosie KA Bunton-Stasyshyn
Victor Tybulewicz
Andrew JH Smith
Elizabeth MC Fisher

Nature Reviews Genetics

Published 1 January 2012

Crick labs

Victor Tybulewicz

Full details

Mechanism and function of Vav1 localization in TCR signaling

Authors (10)

O Ksionda
A Saveliev
R Kochl
J Rapley
M Faroudi
JE Smith-Garvin
C Wulfing
Katrin Rittinger
T Carter
Victor Tybulewicz

Journal of Cell Science

Published 1 January 2012

Crick labs

Full details

Mouse models of aneuploidy

Authors (5)

O Sheppard
FK Wiseman
A Ruparelia
Victor Tybulewicz
EMC Fisher

Scientific World Journal

Published 1 January 2012

Crick labs

Victor Tybulewicz

Full details

Vav1 GEF activity is required for T cell mediated allograft rejection

Authors (9)

Dirk Haubert
Jianping Li
Alexander Saveliev
Thomas Calzascia
Esther Sutter
Barbara Metzler
Daniel Kaiser
Victor Tybulewicz
Gisbert Weckbecker

Transplant Immunology

Published 1 January 2012

Crick labs

Victor Tybulewicz

Full details

Itk controls the spatiotemporal organization of T cell activation

Authors (9)

Kentner L Singleton
Monica Gosh
Radhika D Dandekar
Byron B Au-Yeung
Olga Ksionda
Victor Tybulewicz
Amnon Altman
Deborah J Fowell
Christoph Wülfing

Science Signaling

Published 4 October 2011

Crick labs

Victor Tybulewicz

Full details

Down syndrome: searching for the genetic culprits

Authors (4)

Eva Lana-Elola
Sheona D Watson-Scales
Elizabeth MC Fisher
Victor Tybulewicz

Disease Models & Mechanisms

Published 1 September 2011

Crick labs

Victor Tybulewicz

Full details

Rac1-dependent cell cycle exit of MGE precursors and GABAergic interneuron migration to the cortex

Authors (7)

Marina Vidaki
Simona Tivodar
Katerina Doulgeraki
Victor Tybulewicz
Nicoletta Kessaris
Vassilis Pachnis
Domna Karagogeos

Cerebral Cortex

Published 20 June 2011

Crick labs

Full details

Structural correlates of active-staining following magnetic resonance microscopy in the mouse brain

Authors (10)

JO Cleary
FK Wiseman
FC Norris
AN Price
M Choy
Victor Tybulewicz
RJ Ordidge
S Brandner
EMC Fisher
MF Lythgoe

NeuroImage

Published 1 June 2011

Crick labs

Victor Tybulewicz

Full details

Restoration of pattern recognition receptor costimulation to treat chromoblastomycosis, a chronic fungal infection of the skin

Authors (10)

M da Gloria Sousa
DM Reid
Edina Schweighoffer
Victor Tybulewicz
J Ruland
J Langhorne
S Yamasaki
PR Taylor
SR Almeida
GD Brown

Cell Host & Microbe

Published 1 May 2011

Crick labs

Victor Tybulewicz

Full details

The telomeric part of the human chromosome 21 from Cstb to Prmt2 is not necessary for the locomotor and short-term memory deficits observed in the Tc1 mouse model of Down syndrome

Authors (7)

A Duchon
S Pothion
V Brault
AJ Sharp
Victor Tybulewicz
EMC Fisher
Y Herault

Behavioural Brain Research

Published 1 March 2011

Crick labs

Victor Tybulewicz

Full details

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Tybulewicz lab
Immune Cell Biology Laboratory & Down Syndrome Laboratory
: Publications

Lab content

Publications

Year published

Research topics

Publication type

Journal

A key regulatory role for Vav1 in controlling lipopolysaccharide endotoxemia via macrophage-derived IL-6

Automatic structural parcellation of mouse brain MRI using multi-atlas label fusion

Phosphorylation of the adaptor ASC acts as a molecular switch that controls the formation of speck-like aggregates and inflammasome activity

Protein profiles in Tc1 mice implicate novel pathway perturbations in the Down syndrome brain

Alterations to dendritic spine morphology, but not dendrite patterning, of cortical projection neurons in Tc1 and Ts1Rhr mouse models of Down Syndrome

Massively parallel sequencing reveals the complex structure of an irradiated human chromosome on a mouse background in the Tc1 model of Down syndrome

The BAFF receptor transduces survival signals by co-opting the B cell receptor signaling pathway

Overexpression of the Hspa13 (Stch) gene reduces prion disease incubation time in mice

Altered regulation of tau phosphorylation in a mouse model of down syndrome aging

CLEC-2 and Syk in the megakaryocytic/platelet lineage are essential for development

Genomically humanized mice: technologies and promises

Mechanism and function of Vav1 localization in TCR signaling

Mouse models of aneuploidy

Vav1 GEF activity is required for T cell mediated allograft rejection

Itk controls the spatiotemporal organization of T cell activation

Down syndrome: searching for the genetic culprits

Rac1-dependent cell cycle exit of MGE precursors and GABAergic interneuron migration to the cortex

Structural correlates of active-staining following magnetic resonance microscopy in the mouse brain

Restoration of pattern recognition receptor costimulation to treat chromoblastomycosis, a chronic fungal infection of the skin

The telomeric part of the human chromosome 21 from Cstb to Prmt2 is not necessary for the locomotor and short-term memory deficits observed in the Tc1 mouse model of Down syndrome

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Postdoctoral clinical fellows

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About us

Lab content

Publications

Year published

Research topics

Publication type

Journal

Publications

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