The Advanced Sequencing Team at Crick provides high-quality Next Generation Sequence (NGS) data from a state-of-the-art, multi-platform core facility.
We offer complete project management, from initial project planning and submission with the researcher, through sample preparation and sequencing, and onward to data analysis, which can be performed by the Bioinformatics STP.
We have expertise in a wide range of NGS applications including RNA-Seq, ChIP-Seq, single cell sequencing (10X), genomic sequencing and capture methods.
We run multiple Illumina platforms as well as Ion Torrent and Nanopore.
We also constantly evaluate new technologies and platforms, and automate some of the more laborious of sample prep methods, such as the enrichment protocols offered by Agilent and Illumina.
We are happy to accept pre-made libraries as well as raw samples, all of which undergo an initial, as well as continuous, quality control assessment.
We mostly perform individual projects designed to address a specific biological question but are also supporting long-term efforts within the Crick:
- Exome and targeted sequencing for the TRACERx consortium
- CRISPR screening for the Genetic Modification Service (GeMS)
- Virus sequencing for the Worldwide Influenza Centre
We work only with scientists from the Crick and regretfully cannot accept outside submissions.