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Advanced Sequencing : Publications

Publications

Rohlwink,Ursula K; Figaji,Anthony; Wilkinson,Katalin A; Horswell,Stuart; Sesay,Abdul K; Deffur,Armin; et al

Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity.

Nature Communications (2019) 10, 3767

Singhania,Akul; Graham,Christine M; Gabryšová,Leona; Moreira-Teixeira,Lúcia; Stavropoulos,Evangelos; Pitt,Jonathan M; et al

Transcriptional profiling unveils type I and II interferon networks in blood and tissues across diseases.

Nature Communications (2019) 10, 2887

Rosenthal,Rachel; Cadieux,Elizabeth Larose; Salgado,Roberto; Bakir,Maise Al; Moore,David A; Hiley,Crispin T; et al

Neoantigen-directed immune escape in lung cancer evolution

Nature (2019) 567, 479-485

van der Hooft,Justin JJ; Goldstone,Robert J; Harris,Susan; Burgess,Karl EV; Smith,David GE

Substantial extracellular metabolic differences found between phylogenetically closely related probiotic and pathogenic strains of Escherichia coli.

Frontiers in Microbiology (2019) 10, 252

Gabryšová,Leona; Alvarez-Martinez,Marisol; Luisier,Raphaëlle; Cox,Luke S; Sodenkamp,Jan; Hosking,Caroline; et al

c-Maf controls immune responses by regulating disease-specific gene networks and repressing IL-2 in CD4+ T cells

Nature Immunology (2018) 19, 497-507

Turajlic,Samra; Xu,Hang; Litchfield,Kevin; Rowan,Andrew; Horswell,Stuart; Chambers,Tim; et al

Deterministic evolutionary trajectories influence primary tumor growth: TRACERx Renal

Cell (2018) 173, 595-610.e11

Zatreanu,Diana; Han,Zhong; Mitter,Richard; Tumini,Emanuela; Williams,Hannah; Gregersen,Lea; et al

Elongation factor TFIIS prevents transcription stress and R-loop accumulation to maintain genome stability

Molecular Cell (2019) 76, Epub ahead of print

Young,Joanna; Dominicus,Caia; Wagener,Jeanette; Butterworth,Simon; Ye,Xingda; Kelly,Gavin; et al

A CRISPR platform for targeted in vivo screens identifies Toxoplasma gondii virulence factors in mice.

Nature Communications (2019) 10, 3963

Mortimer,Thomas; Wainwright,Elanor N; Patel,Harshil; Siow,Bernard M; Jaunmuktane,Zane; Brandner,Sebastian; et al

Redistribution of EZH2 promotes malignant phenotypes by rewiring developmental programmes.

EMBO Reports (2019) e48155

Ombrato,Luigi; Nolan,Emma; Kurelac,Ivana; Mavousian,Antranik; Bridgeman,Victoria Louise; Heinze,Ivonne; et al

Metastatic-niche labelling reveals parenchymal cells with stem features.

Nature (2019) 572, 603-608

Bonnefont,Jerome; Tiberi,Luca; van den Ameele,Jelle; Potier,Delphine; Gaber,Zachary B; Lin,Xionghui; et al

Cortical neurogenesis requires Bcl6-mediated transcriptional repression of multiple self-renewal-promoting extrinsic pathways.

Neuron (2019) 103, Epub ahead of print

Mourikis,Thanos P; Benedetti,Lorena; Foxall,Elizabeth; Temelkovski,Damjan; Nulsen,Joel; Perner,Juliane; et al

Patient-specific cancer genes contribute to recurrently perturbed pathways and establish therapeutic vulnerabilities in esophageal adenocarcinoma.

Nature Communications (2019) 10, 3101