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Advanced Sequencing : Publications

Publications

Rohlwink,Ursula K; Figaji,Anthony; Wilkinson,Katalin A; Horswell,Stuart; Sesay,Abdul K; Deffur,Armin; et al

Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity.

Nature Communications (2019) 10, 3767

Singhania,Akul; Graham,Christine M; Gabryšová,Leona; Moreira-Teixeira,Lúcia; Stavropoulos,Evangelos; Pitt,Jonathan M; et al

Transcriptional profiling unveils type I and II interferon networks in blood and tissues across diseases.

Nature Communications (2019) 10, 2887

Rosenthal,Rachel; Cadieux,Elizabeth Larose; Salgado,Roberto; Bakir,Maise Al; Moore,David A; Hiley,Crispin T; et al

Neoantigen-directed immune escape in lung cancer evolution

Nature (2019) 567, 479-485

van der Hooft,Justin JJ; Goldstone,Robert J; Harris,Susan; Burgess,Karl EV; Smith,David GE

Substantial extracellular metabolic differences found between phylogenetically closely related probiotic and pathogenic strains of Escherichia coli.

Frontiers in Microbiology (2019) 10, 252

Bagnati,Marta; Moreno-Moral,Aida; Ko,Jeong-Hun; Nicod,Jérôme; Harmston,Nathan; Imprialou,Martha; et al

Systems genetics identifies a macrophage cholesterol network associated with physiological wound healing.

JCI Insight (2019) 4, e125736

Gabryšová,Leona; Alvarez-Martinez,Marisol; Luisier,Raphaëlle; Cox,Luke S; Sodenkamp,Jan; Hosking,Caroline; et al

c-Maf controls immune responses by regulating disease-specific gene networks and repressing IL-2 in CD4+ T cells

Nature Immunology (2018) 19, 497-507

Zatreanu,Diana; Han,Zhong; Mitter,Richard; Tumini,Emanuela; Williams,Hannah; Gregersen,Lea; et al

Elongation factor TFIIS prevents transcription stress and R-loop accumulation to maintain genome stability

Molecular Cell (2019) 76, 57-69.e9

Blomfield,Isabelle M; Rocamonde,Brenda; Masdeu,Maria Del Mar; Mulugeta,Eskeatnaf; Vaga,Stefania; van den Berg,Debbie LC; et al

Id4 promotes the elimination of the pro-activation factor Ascl1 to maintain quiescence of adult hippocampal stem cells.

Elife (2019) 8, Epub ahead of print

Bonnefont,Jerome; Tiberi,Luca; van den Ameele,Jelle; Potier,Delphine; Gaber,Zachary B; Lin,Xionghui; et al

Cortical neurogenesis requires Bcl6-mediated transcriptional repression of multiple self-renewal-promoting extrinsic pathways.

Neuron (2019) 103, 1096-1108.e4

Gentsch,George E; Spruce,Thomas; Owens,Nick DL; Smith,James C

Maternal pluripotency factors initiate extensive chromatin remodelling to predefine first response to inductive signals.

Nature Communications (2019) 10, 4269

Molina-Arcas,Miriam; Moore,Christopher; Rana,Sareena; van Maldegem,Febe; Mugarza,Edurne; Romero-Clavijo,Pablo; et al

Development of combination therapies to maximize the impact of KRAS-G12C inhibitors in lung cancer

Science Translational Medicine (2019) 11, eaaw7999

Young,Joanna; Dominicus,Caia; Wagener,Jeanette; Butterworth,Simon; Ye,Xingda; Kelly,Gavin; et al

A CRISPR platform for targeted in vivo screens identifies Toxoplasma gondii virulence factors in mice.

Nature Communications (2019) 10, 3963