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A HiSeq flowcell. Credit: Fiona Byrne. Toggle to view hero caption Advanced Sequencing : Publications Lab MenuLab Menu Overview Applications Equipment Publications Members Breadcrumb Home Research Platforms & facilities Advanced Sequencing Publications Publications Displaying 1 - 10 of 132Last updated : 10 August 2020 02:55 An optimized protocol for ChIP-Seq from human embryonic stem cell cultures Authors (2)Adrienne SullivanSilvia Santos STAR Protocols Published 17 July 2020 Crick labs/ facilitiesSilvia SantosAdvanced SequencingBioinformatics and BiostatisticsFull details Combined targeting of G protein-coupled receptor and EGF receptor signaling overcomes resistance to PI3K pathway inhibitors in PTEN-null triple negative breast cancer Authors (7)Davide ZecchinChristopher Moore Fanourios Michailidis Stuart HorswellSareena RanaMichael HowellJulian Downward EMBO Molecular Medicine Published 16 July 2020 Crick labs/ facilitiesJulian DownwardBioinformatics and BiostatisticsHigh Throughput ScreeningAdvanced SequencingCell ServicesExperimental HistopathologyGenomics/Equipment ParkBiological Research FacilityFull details Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers Authors (341) Catherine F Houlihan Nina Vora Thomas Byrne Dan Lewer Gavin Kelly Judith Heaney[...] Andrew Hayward Richard Gilson Gavin KellyFiona Roberts Emine Hatipoglu The Lancet Published 25 July 2020 Crick labs/ facilitiesLuiz Pedro CarvalhoMike BlackmanDominique BonnetPeter Cherepanov Steve GamblinMaximiliano GutierrezGeorge KassiotisPaul NurseAnne O’GarraVenizelos PapayannopoulosLucia Prieto-GodinoPeter RatcliffeCaetano Reis e SousaErik SahaiCharles SwantonMoritz TreeckJames TurnerJernej UleKaren VousdenAndreas WackSonia GandhiRupert BealeAdam SaterialeAdvanced SequencingCell ServicesBioinformatics and BiostatisticsElectron MicroscopyExperimental HistopathologyFlow CytometryGenomics/Equipment ParkHigh Throughput ScreeningMetabolomicsPeptide ChemistryStructural BiologyFermentationWorldwide Influenza CentreHuman Embryonic Stem CellScientific computingFull details Restriction of memory B cell differentiation at the germinal center B cell positive selection stage Authors (13) Amparo Toboso-Navasa Arief Gunawan Giulia Morlino Rinako Nakagawa Andrea Taddei Djamil Damry[...] Martin JanzGeorge Kassiotis Robert Brink Martin EilersDinis Calado Journal of Experimental Medicine Published 6 July 2020 Crick labs/ facilitiesDinis CaladoGeorge KassiotisBioinformatics and BiostatisticsAdvanced SequencingLight MicroscopyExperimental HistopathologyFlow CytometryBiological Research FacilityFull details CARD14E138A signalling in keratinocytes induces TNF-dependent skin and systemic inflammation Authors (7)Joan Manils Louise V WebbAshleigh Howes Julia Janzen Stefan Boeing Anne M BowcockSteve Ley eLife Published 29 June 2020 Crick labs/ facilitiesBioinformatics and BiostatisticsAdvanced SequencingExperimental HistopathologyFlow CytometryBiological Research FacilityFull details Transcriptomic analysis reveals diverse gene expression changes in airway macrophages during experimental allergic airway disease Authors (3) William J BranchettAnne O'Garra Clare M Lloyd Wellcome Open Research Published 22 June 2020 Crick labs/ facilitiesAnne O’GarraAdvanced SequencingFull details Scalable and robust SARS-CoV-2 testing in an academic center Authors (81) The Crick COVID-19 Consortium Jim Aitken Karen AmbroseSam BarrellRupert BealeGanka Bineva-Todd[...]Philip WalkerSophia Ward Wai Keong WongJoshua WrightMary Wu Nature Biotechnology Published 18 June 2020 Crick labs/ facilitiesPeter Cherepanov Steve GamblinGeorge KassiotisVenizelos PapayannopoulosPeter RatcliffeCaetano Reis e SousaCharles SwantonJames TurnerAndreas WackSonia GandhiRupert BealeAdvanced SequencingGenomics/Equipment ParkHigh Throughput ScreeningMetabolomicsPeptide ChemistryStructural BiologyFermentationScientific computingFull details γδ T cells compose a developmentally regulated intrauterine population and protect against vaginal candidiasis Authors (18) L Monin DS Ushakov H Arnesen N Bah A Jandke M Muñoz-Ruiz[...] M Curtis H Carlsen U Steinhoff P BoysenAdrian Hayday Mucosal Immunology Published 29 May 2020 Crick labs/ facilitiesAdrian HaydayBioinformatics and BiostatisticsExperimental HistopathologyAdvanced SequencingFlow CytometryBiological Research FacilityFull details The BCL-2 pathway preserves mammalian genome integrity by eliminating recombination-defective oocytes Authors (12)Elias Elinati Agata P ZielinskaAfshan McCarthy Nada KubikovaValdone MaciulyteShantha Mahadevaiah[...]Andrew Ojarikre Dagan WellsKathy Niakan Melina SchuhJames Turner Nature Communications Published 25 May 2020 Crick labs/ facilitiesKathy NiakanJames TurnerAdvanced SequencingLight MicroscopyExperimental HistopathologyBiological Research FacilityFull details Unintended on-target chromosomal instability following CRISPR/Cas9 single gene targeting Authors (5)Aśka PrzewrockaAndrew RowanRachel Rosenthal N KanuCharles Swanton Annals of Oncology Published 15 May 2020 Crick labs/ facilitiesCharles SwantonAdvanced SequencingHigh Throughput ScreeningFull details Pagination Current page 1 Page 2 Page 3 Page 4 Page 5 Page 6 Page 7 Page 8 Page 9 … Next page Next Last page Last Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
An optimized protocol for ChIP-Seq from human embryonic stem cell cultures Authors (2)Adrienne SullivanSilvia Santos STAR Protocols Published 17 July 2020 Crick labs/ facilitiesSilvia SantosAdvanced SequencingBioinformatics and BiostatisticsFull details
Combined targeting of G protein-coupled receptor and EGF receptor signaling overcomes resistance to PI3K pathway inhibitors in PTEN-null triple negative breast cancer Authors (7)Davide ZecchinChristopher Moore Fanourios Michailidis Stuart HorswellSareena RanaMichael HowellJulian Downward EMBO Molecular Medicine Published 16 July 2020 Crick labs/ facilitiesJulian DownwardBioinformatics and BiostatisticsHigh Throughput ScreeningAdvanced SequencingCell ServicesExperimental HistopathologyGenomics/Equipment ParkBiological Research FacilityFull details
Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers Authors (341) Catherine F Houlihan Nina Vora Thomas Byrne Dan Lewer Gavin Kelly Judith Heaney[...] Andrew Hayward Richard Gilson Gavin KellyFiona Roberts Emine Hatipoglu The Lancet Published 25 July 2020 Crick labs/ facilitiesLuiz Pedro CarvalhoMike BlackmanDominique BonnetPeter Cherepanov Steve GamblinMaximiliano GutierrezGeorge KassiotisPaul NurseAnne O’GarraVenizelos PapayannopoulosLucia Prieto-GodinoPeter RatcliffeCaetano Reis e SousaErik SahaiCharles SwantonMoritz TreeckJames TurnerJernej UleKaren VousdenAndreas WackSonia GandhiRupert BealeAdam SaterialeAdvanced SequencingCell ServicesBioinformatics and BiostatisticsElectron MicroscopyExperimental HistopathologyFlow CytometryGenomics/Equipment ParkHigh Throughput ScreeningMetabolomicsPeptide ChemistryStructural BiologyFermentationWorldwide Influenza CentreHuman Embryonic Stem CellScientific computingFull details
Restriction of memory B cell differentiation at the germinal center B cell positive selection stage Authors (13) Amparo Toboso-Navasa Arief Gunawan Giulia Morlino Rinako Nakagawa Andrea Taddei Djamil Damry[...] Martin JanzGeorge Kassiotis Robert Brink Martin EilersDinis Calado Journal of Experimental Medicine Published 6 July 2020 Crick labs/ facilitiesDinis CaladoGeorge KassiotisBioinformatics and BiostatisticsAdvanced SequencingLight MicroscopyExperimental HistopathologyFlow CytometryBiological Research FacilityFull details
CARD14E138A signalling in keratinocytes induces TNF-dependent skin and systemic inflammation Authors (7)Joan Manils Louise V WebbAshleigh Howes Julia Janzen Stefan Boeing Anne M BowcockSteve Ley eLife Published 29 June 2020 Crick labs/ facilitiesBioinformatics and BiostatisticsAdvanced SequencingExperimental HistopathologyFlow CytometryBiological Research FacilityFull details
Transcriptomic analysis reveals diverse gene expression changes in airway macrophages during experimental allergic airway disease Authors (3) William J BranchettAnne O'Garra Clare M Lloyd Wellcome Open Research Published 22 June 2020 Crick labs/ facilitiesAnne O’GarraAdvanced SequencingFull details
Scalable and robust SARS-CoV-2 testing in an academic center Authors (81) The Crick COVID-19 Consortium Jim Aitken Karen AmbroseSam BarrellRupert BealeGanka Bineva-Todd[...]Philip WalkerSophia Ward Wai Keong WongJoshua WrightMary Wu Nature Biotechnology Published 18 June 2020 Crick labs/ facilitiesPeter Cherepanov Steve GamblinGeorge KassiotisVenizelos PapayannopoulosPeter RatcliffeCaetano Reis e SousaCharles SwantonJames TurnerAndreas WackSonia GandhiRupert BealeAdvanced SequencingGenomics/Equipment ParkHigh Throughput ScreeningMetabolomicsPeptide ChemistryStructural BiologyFermentationScientific computingFull details
γδ T cells compose a developmentally regulated intrauterine population and protect against vaginal candidiasis Authors (18) L Monin DS Ushakov H Arnesen N Bah A Jandke M Muñoz-Ruiz[...] M Curtis H Carlsen U Steinhoff P BoysenAdrian Hayday Mucosal Immunology Published 29 May 2020 Crick labs/ facilitiesAdrian HaydayBioinformatics and BiostatisticsExperimental HistopathologyAdvanced SequencingFlow CytometryBiological Research FacilityFull details
The BCL-2 pathway preserves mammalian genome integrity by eliminating recombination-defective oocytes Authors (12)Elias Elinati Agata P ZielinskaAfshan McCarthy Nada KubikovaValdone MaciulyteShantha Mahadevaiah[...]Andrew Ojarikre Dagan WellsKathy Niakan Melina SchuhJames Turner Nature Communications Published 25 May 2020 Crick labs/ facilitiesKathy NiakanJames TurnerAdvanced SequencingLight MicroscopyExperimental HistopathologyBiological Research FacilityFull details
Unintended on-target chromosomal instability following CRISPR/Cas9 single gene targeting Authors (5)Aśka PrzewrockaAndrew RowanRachel Rosenthal N KanuCharles Swanton Annals of Oncology Published 15 May 2020 Crick labs/ facilitiesCharles SwantonAdvanced SequencingHigh Throughput ScreeningFull details
