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Breadcrumb Advanced Sequencing Advanced Sequencing : Publications Lab contentLab contentIn this section Overview Applications Equipment Publications Members A HiSeq flowcell. Credit: Fiona Byrne. Toggle to view hero caption Publications Displaying 71 - 80 of 346Last updated : 28 March 2024 02:30 RSC and GRFs confer promoter directionality by restricting divergent noncoding transcription Authors (6)Chun Kit WuClaudia Vivori Harshil PatelTheodora SideriFabien MorettoFolkert Van Werven Life Science Alliance Published 1 December 2022 Crick labs/ facilitiesFolkert van WervenBioinformatics and BiostatisticsFermentationAdvanced SequencingFull details The cortical hem lacks stem cell potential despite expressing SOX9 and HOPX Authors (5)Alessia CaramelloChristophe Galichet Miriam Llorian SopenaRobin Lovell-BadgeKarine Rizzoti Developmental Neurobiology Published 1 October 2022 Crick labs/ facilitiesRobin Lovell-BadgeBioinformatics and BiostatisticsLight MicroscopyBiological Research FacilityAdvanced SequencingFull details SARS-CoV-2 ORF6 disrupts innate immune signalling by inhibiting cellular mRNA export Authors (7)Ross HallAnabel GuedanMelvyn YapGeorge Young Ruth HarveyJonathan StoyeKate Bishop PLOS Pathogens Published 25 August 2022 Crick labs/ facilitiesJonathan StoyeKate BishopWorldwide Influenza CentreBioinformatics and BiostatisticsAdvanced SequencingFull details Microbe capture by splenic macrophages triggers sepsis via T cell-death-dependent neutrophil lifespan shortening Authors (16) Marianna Ioannou Dennis Hoving Iker Valle AramburuMia Temkin Nathalia M De Vasconcelos Theodora Dorita Tsourouktsoglou[...]Markus Ralser Sascha David Klaus Stahl Christian BodeVenizelos Papayannopoulos Nature Communications Published 9 August 2022 Crick labs/ facilitiesMarkus RalserVenizelos PapayannopoulosBioinformatics and BiostatisticsAdvanced SequencingFull details Therapeutic KRASG12C inhibition drives effective interferon-mediated antitumor immunity in immunogenic lung cancers Authors (14) Edurne MugarzaFebe VanMaldegemJesse BoumelhaChristopher MooreSareena Rana Miriam Llorian Sopena[...] Pablo Romero-ClavijoKarishma ValandMegan ColeMiriam Molina ArcasJulian Downward Science advances Published 22 July 2022 Crick labs/ facilitiesJulian DownwardBioinformatics and BiostatisticsFlow CytometryExperimental HistopathologyCell ServicesBiological Research FacilityAdvanced SequencingFull details The relative binding position of Nck and Grb2 adaptors impacts actin-based motility of Vaccinia virus Authors (2)Angika BasantMichael Way eLife Published 7 July 2022 Crick labs/ facilitiesMichael WayCell ServicesAdvanced SequencingFull details Early functional mismatch between breast cancer cells and their tumour microenvironment suppresses long term growth Authors (7)Anna Perdrix Rosell Oscar Maiques Joshua Alexander James Martin Probir ChakravartyLuigi Ombrato Victoria Sanz-MorenoIlaria Malanchi Cancer Letters Published 28 September 2022 Crick labs/ facilitiesIlaria MalanchiBioinformatics and BiostatisticsFlow CytometryExperimental HistopathologyBiological Research FacilityAdvanced SequencingFull details GREM1 is required to maintain cellular heterogeneity in pancreatic cancer Authors (21) Linxiang Lan Theodore Evan Huafu Li Aasia Hussain E Josue Ruiz May Zaw Thin[...]Emma Nye Yulong He Changhua Zhang Anguraj SadanandamAxel Behrens Nature Published 7 July 2022 Crick labs/ facilitiesIlaria MalanchiGeorge KassiotisAxel BehrensExperimental HistopathologyBioinformatics and BiostatisticsLight MicroscopyFlow CytometryBiological Research FacilityAdvanced SequencingFull details Disrupted control of origin activation compromises genome integrity upon destabilization of Polε and dysfunction of the TRP53-CDKN1A/P21 axis Authors (12)Valerie Borel Stefan Boeing Niek Van Wietmarschen Sriram Sridharan Bethany Rebekah Hill Luigi Ombrato[...]Deb JacksonRobert GoldstoneSimon Boulton Andre Nussenzweig Roberto Bellelli Cell Reports Published 31 May 2022 Crick labs/ facilitiesSimon BoultonBioinformatics and BiostatisticsAdvanced SequencingFull details A family of conserved bacterial virulence factors dampens interferon responses by blocking calcium signaling Authors (24) Noémie Alphonse Joseph J Wanford Andrew A Voak Jack Gay Shayla Venkhaya Owen Burroughs[...] Martin W Berchtold Julien RC BergeronAndreas Wack Cammie F Lesser Charlotte Odendall Cell Published 23 June 2022 Crick labs/ facilitiesAndreas WackBioinformatics and BiostatisticsExperimental HistopathologyAdvanced SequencingFull details Pagination First page First Previous page Previous … Page 4 Page 5 Page 6 Page 7 Current page 8 Page 9 Page 10 Page 11 Page 12 … Next page Next Last page Last Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
RSC and GRFs confer promoter directionality by restricting divergent noncoding transcription Authors (6)Chun Kit WuClaudia Vivori Harshil PatelTheodora SideriFabien MorettoFolkert Van Werven Life Science Alliance Published 1 December 2022 Crick labs/ facilitiesFolkert van WervenBioinformatics and BiostatisticsFermentationAdvanced SequencingFull details
The cortical hem lacks stem cell potential despite expressing SOX9 and HOPX Authors (5)Alessia CaramelloChristophe Galichet Miriam Llorian SopenaRobin Lovell-BadgeKarine Rizzoti Developmental Neurobiology Published 1 October 2022 Crick labs/ facilitiesRobin Lovell-BadgeBioinformatics and BiostatisticsLight MicroscopyBiological Research FacilityAdvanced SequencingFull details
SARS-CoV-2 ORF6 disrupts innate immune signalling by inhibiting cellular mRNA export Authors (7)Ross HallAnabel GuedanMelvyn YapGeorge Young Ruth HarveyJonathan StoyeKate Bishop PLOS Pathogens Published 25 August 2022 Crick labs/ facilitiesJonathan StoyeKate BishopWorldwide Influenza CentreBioinformatics and BiostatisticsAdvanced SequencingFull details
Microbe capture by splenic macrophages triggers sepsis via T cell-death-dependent neutrophil lifespan shortening Authors (16) Marianna Ioannou Dennis Hoving Iker Valle AramburuMia Temkin Nathalia M De Vasconcelos Theodora Dorita Tsourouktsoglou[...]Markus Ralser Sascha David Klaus Stahl Christian BodeVenizelos Papayannopoulos Nature Communications Published 9 August 2022 Crick labs/ facilitiesMarkus RalserVenizelos PapayannopoulosBioinformatics and BiostatisticsAdvanced SequencingFull details
Therapeutic KRASG12C inhibition drives effective interferon-mediated antitumor immunity in immunogenic lung cancers Authors (14) Edurne MugarzaFebe VanMaldegemJesse BoumelhaChristopher MooreSareena Rana Miriam Llorian Sopena[...] Pablo Romero-ClavijoKarishma ValandMegan ColeMiriam Molina ArcasJulian Downward Science advances Published 22 July 2022 Crick labs/ facilitiesJulian DownwardBioinformatics and BiostatisticsFlow CytometryExperimental HistopathologyCell ServicesBiological Research FacilityAdvanced SequencingFull details
The relative binding position of Nck and Grb2 adaptors impacts actin-based motility of Vaccinia virus Authors (2)Angika BasantMichael Way eLife Published 7 July 2022 Crick labs/ facilitiesMichael WayCell ServicesAdvanced SequencingFull details
Early functional mismatch between breast cancer cells and their tumour microenvironment suppresses long term growth Authors (7)Anna Perdrix Rosell Oscar Maiques Joshua Alexander James Martin Probir ChakravartyLuigi Ombrato Victoria Sanz-MorenoIlaria Malanchi Cancer Letters Published 28 September 2022 Crick labs/ facilitiesIlaria MalanchiBioinformatics and BiostatisticsFlow CytometryExperimental HistopathologyBiological Research FacilityAdvanced SequencingFull details
GREM1 is required to maintain cellular heterogeneity in pancreatic cancer Authors (21) Linxiang Lan Theodore Evan Huafu Li Aasia Hussain E Josue Ruiz May Zaw Thin[...]Emma Nye Yulong He Changhua Zhang Anguraj SadanandamAxel Behrens Nature Published 7 July 2022 Crick labs/ facilitiesIlaria MalanchiGeorge KassiotisAxel BehrensExperimental HistopathologyBioinformatics and BiostatisticsLight MicroscopyFlow CytometryBiological Research FacilityAdvanced SequencingFull details
Disrupted control of origin activation compromises genome integrity upon destabilization of Polε and dysfunction of the TRP53-CDKN1A/P21 axis Authors (12)Valerie Borel Stefan Boeing Niek Van Wietmarschen Sriram Sridharan Bethany Rebekah Hill Luigi Ombrato[...]Deb JacksonRobert GoldstoneSimon Boulton Andre Nussenzweig Roberto Bellelli Cell Reports Published 31 May 2022 Crick labs/ facilitiesSimon BoultonBioinformatics and BiostatisticsAdvanced SequencingFull details
A family of conserved bacterial virulence factors dampens interferon responses by blocking calcium signaling Authors (24) Noémie Alphonse Joseph J Wanford Andrew A Voak Jack Gay Shayla Venkhaya Owen Burroughs[...] Martin W Berchtold Julien RC BergeronAndreas Wack Cammie F Lesser Charlotte Odendall Cell Published 23 June 2022 Crick labs/ facilitiesAndreas WackBioinformatics and BiostatisticsExperimental HistopathologyAdvanced SequencingFull details