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Breadcrumb Advanced Sequencing Advanced Sequencing : Publications Lab contentLab contentIn this section Overview Applications Equipment Publications Members A HiSeq flowcell. Credit: Fiona Byrne. Toggle to view hero caption Publications Displaying 81 - 90 of 350Last updated : 25 April 2024 02:22 Early functional mismatch between breast cancer cells and their tumour microenvironment suppresses long term growth Authors (7)Anna Perdrix Rosell Oscar Maiques Joshua Alexander James Martin Probir ChakravartyLuigi Ombrato Victoria Sanz-MorenoIlaria Malanchi Cancer Letters Published 28 September 2022 Crick labs/ facilitiesIlaria MalanchiBioinformatics and BiostatisticsFlow CytometryExperimental HistopathologyBiological Research FacilityAdvanced SequencingFull details GREM1 is required to maintain cellular heterogeneity in pancreatic cancer Authors (21) Linxiang Lan Theodore Evan Huafu Li Aasia Hussain E Josue Ruiz May Zaw Thin[...]Emma Nye Yulong He Changhua Zhang Anguraj SadanandamAxel Behrens Nature Published 7 July 2022 Crick labs/ facilitiesIlaria MalanchiGeorge KassiotisAxel BehrensExperimental HistopathologyBioinformatics and BiostatisticsLight MicroscopyFlow CytometryBiological Research FacilityAdvanced SequencingFull details Disrupted control of origin activation compromises genome integrity upon destabilization of Polε and dysfunction of the TRP53-CDKN1A/P21 axis Authors (12)Valerie BorelStefan Boeing Niek Van Wietmarschen Sriram Sridharan Bethany Rebekah Hill Luigi Ombrato[...]Deb JacksonRobert GoldstoneSimon Boulton Andre Nussenzweig Roberto Bellelli Cell Reports Published 31 May 2022 Crick labs/ facilitiesSimon BoultonBioinformatics and BiostatisticsAdvanced SequencingFull details A family of conserved bacterial virulence factors dampens interferon responses by blocking calcium signaling Authors (24) Noémie Alphonse Joseph J Wanford Andrew A Voak Jack Gay Shayla Venkhaya Owen Burroughs[...] Martin W Berchtold Julien RC BergeronAndreas Wack Cammie F Lesser Charlotte Odendall Cell Published 23 June 2022 Crick labs/ facilitiesAndreas WackBioinformatics and BiostatisticsExperimental HistopathologyAdvanced SequencingFull details Sox2 levels regulate the chromatin occupancy of WNT mediators in epiblast progenitors responsible for vertebrate body formation Authors (7)Robert Blassberg Harshil Patel Thomas Watson Mina GoutiVicki MetzisJoaquina Delas VivesJames Briscoe Nature Cell Biology Published 1 May 2022 Crick labs/ facilitiesJames BriscoeBioinformatics and BiostatisticsFlow CytometryAdvanced SequencingFull details Single cell analyses identify a highly regenerative and homogenous human CD34+ hematopoietic stem cell population Authors (9) Fernando Anjos-Afonso Florian Buettner Syed A MianHefin RhysJimena Perez-LloretManuel Garcia Albornoz Namrata RastogiLinda Ariza-McnaughtonDominique Bonnet Nature Communications Published 19 April 2022 Crick labs/ facilitiesDominique BonnetFlow CytometryAdvanced SequencingBiological Research FacilityFull details USP25 promotes pathological HIF-1-driven metabolic reprogramming and is a potential therapeutic target in pancreatic cancer Authors (19)Jessica Nelson May Zaw ThinTheo Evan Steven HowellMary WuBruna Almeida[...]Bram Snijders Andreas Prachalias Yoh Zen Debashis SarkerAxel Behrens Nature Communications Published 19 April 2022 Crick labs/ facilitiesPeter RatcliffeAxel BehrensProteomicsMetabolomicsHigh Throughput ScreeningExperimental HistopathologyBioinformatics and BiostatisticsAdvanced SequencingFull details Cell-intrinsic aryl hydrocarbon receptor signalling is required for the resolution of injury-induced colonic stem cells Authors (15)Kathleen ShahMuralidhara Maradana M Joaquina Delàs Amina Metidji Frederike GraelmannMiriam Llorian Sopena[...]Gavin KellyChris Cheshire Deendyal Bhurta Sandip B BharateBrigitta Stockinger Nature Communications Published 5 April 2022 Crick labs/ facilitiesGitta StockingerNicholas LuscombeJames BriscoeBioinformatics and BiostatisticsLight MicroscopyFlow CytometryExperimental HistopathologyBiological Research FacilityAdvanced SequencingFull details Rostrocaudal patterning and neural crest differentiation of human pre-neural spinal cord progenitors in vitro Authors (8)Fay CooperGeorge Gentsch Richard MitterCamille BouissouLyn Healy Ana Hernandez RodriguezJim Smith Andreia S Bernardo Stem Cell Reports Published 12 April 2022 Crick labs/ facilitiesJim SmithHuman Embryonic Stem CellBioinformatics and BiostatisticsLight MicroscopyAdvanced SequencingFull details A network of transcription factors governs the dynamics of NODAL/Activin transcriptional responses Authors (7)Davide Coda Harshil PatelIlaria Gori Tessa E GaarenstroomOk-Ryul SongMichael HowellCaroline Hill Journal of Cell Science Published 15 April 2022 Crick labs/ facilitiesCaroline HillHigh Throughput ScreeningBioinformatics and BiostatisticsFlow CytometryCell ServicesAdvanced SequencingFull details Pagination First page First Previous page Previous … Page 5 Page 6 Page 7 Page 8 Current page 9 Page 10 Page 11 Page 12 Page 13 … Next page Next Last page Last Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Early functional mismatch between breast cancer cells and their tumour microenvironment suppresses long term growth Authors (7)Anna Perdrix Rosell Oscar Maiques Joshua Alexander James Martin Probir ChakravartyLuigi Ombrato Victoria Sanz-MorenoIlaria Malanchi Cancer Letters Published 28 September 2022 Crick labs/ facilitiesIlaria MalanchiBioinformatics and BiostatisticsFlow CytometryExperimental HistopathologyBiological Research FacilityAdvanced SequencingFull details
GREM1 is required to maintain cellular heterogeneity in pancreatic cancer Authors (21) Linxiang Lan Theodore Evan Huafu Li Aasia Hussain E Josue Ruiz May Zaw Thin[...]Emma Nye Yulong He Changhua Zhang Anguraj SadanandamAxel Behrens Nature Published 7 July 2022 Crick labs/ facilitiesIlaria MalanchiGeorge KassiotisAxel BehrensExperimental HistopathologyBioinformatics and BiostatisticsLight MicroscopyFlow CytometryBiological Research FacilityAdvanced SequencingFull details
Disrupted control of origin activation compromises genome integrity upon destabilization of Polε and dysfunction of the TRP53-CDKN1A/P21 axis Authors (12)Valerie BorelStefan Boeing Niek Van Wietmarschen Sriram Sridharan Bethany Rebekah Hill Luigi Ombrato[...]Deb JacksonRobert GoldstoneSimon Boulton Andre Nussenzweig Roberto Bellelli Cell Reports Published 31 May 2022 Crick labs/ facilitiesSimon BoultonBioinformatics and BiostatisticsAdvanced SequencingFull details
A family of conserved bacterial virulence factors dampens interferon responses by blocking calcium signaling Authors (24) Noémie Alphonse Joseph J Wanford Andrew A Voak Jack Gay Shayla Venkhaya Owen Burroughs[...] Martin W Berchtold Julien RC BergeronAndreas Wack Cammie F Lesser Charlotte Odendall Cell Published 23 June 2022 Crick labs/ facilitiesAndreas WackBioinformatics and BiostatisticsExperimental HistopathologyAdvanced SequencingFull details
Sox2 levels regulate the chromatin occupancy of WNT mediators in epiblast progenitors responsible for vertebrate body formation Authors (7)Robert Blassberg Harshil Patel Thomas Watson Mina GoutiVicki MetzisJoaquina Delas VivesJames Briscoe Nature Cell Biology Published 1 May 2022 Crick labs/ facilitiesJames BriscoeBioinformatics and BiostatisticsFlow CytometryAdvanced SequencingFull details
Single cell analyses identify a highly regenerative and homogenous human CD34+ hematopoietic stem cell population Authors (9) Fernando Anjos-Afonso Florian Buettner Syed A MianHefin RhysJimena Perez-LloretManuel Garcia Albornoz Namrata RastogiLinda Ariza-McnaughtonDominique Bonnet Nature Communications Published 19 April 2022 Crick labs/ facilitiesDominique BonnetFlow CytometryAdvanced SequencingBiological Research FacilityFull details
USP25 promotes pathological HIF-1-driven metabolic reprogramming and is a potential therapeutic target in pancreatic cancer Authors (19)Jessica Nelson May Zaw ThinTheo Evan Steven HowellMary WuBruna Almeida[...]Bram Snijders Andreas Prachalias Yoh Zen Debashis SarkerAxel Behrens Nature Communications Published 19 April 2022 Crick labs/ facilitiesPeter RatcliffeAxel BehrensProteomicsMetabolomicsHigh Throughput ScreeningExperimental HistopathologyBioinformatics and BiostatisticsAdvanced SequencingFull details
Cell-intrinsic aryl hydrocarbon receptor signalling is required for the resolution of injury-induced colonic stem cells Authors (15)Kathleen ShahMuralidhara Maradana M Joaquina Delàs Amina Metidji Frederike GraelmannMiriam Llorian Sopena[...]Gavin KellyChris Cheshire Deendyal Bhurta Sandip B BharateBrigitta Stockinger Nature Communications Published 5 April 2022 Crick labs/ facilitiesGitta StockingerNicholas LuscombeJames BriscoeBioinformatics and BiostatisticsLight MicroscopyFlow CytometryExperimental HistopathologyBiological Research FacilityAdvanced SequencingFull details
Rostrocaudal patterning and neural crest differentiation of human pre-neural spinal cord progenitors in vitro Authors (8)Fay CooperGeorge Gentsch Richard MitterCamille BouissouLyn Healy Ana Hernandez RodriguezJim Smith Andreia S Bernardo Stem Cell Reports Published 12 April 2022 Crick labs/ facilitiesJim SmithHuman Embryonic Stem CellBioinformatics and BiostatisticsLight MicroscopyAdvanced SequencingFull details
A network of transcription factors governs the dynamics of NODAL/Activin transcriptional responses Authors (7)Davide Coda Harshil PatelIlaria Gori Tessa E GaarenstroomOk-Ryul SongMichael HowellCaroline Hill Journal of Cell Science Published 15 April 2022 Crick labs/ facilitiesCaroline HillHigh Throughput ScreeningBioinformatics and BiostatisticsFlow CytometryCell ServicesAdvanced SequencingFull details