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Bioinformatic visualisation of protein binding along a human chromosome, courtesy of Federico Agostini and Nick Luscombe. Toggle to view hero caption Bioinformatics and Biostatistics : Publications Lab MenuLab Menu Overview Publications Breadcrumb Home Research Platforms & facilities Bioinformatics and Biostatistics Publications Publications Displaying 1 - 10 of 247Last updated : 13 August 2020 03:39 Butyrophilin-like proteins display combinatorial diversity in selecting and maintaining signature intraepithelial γδ T cell compartments Authors (12) Anett Jandke Daisy Melandri Leticia Monin Dmitry S Ushakov Adam G Laing Pierre Vantourout[...] Takeshi Nitta Tomoya Narita Hiroshi Takayanagi Regina FeederleAdrian Hayday Nature Communications Published 28 July 2020 Crick labs/ facilitiesAdrian HaydayBioinformatics and BiostatisticsCell ServicesExperimental HistopathologyFlow CytometryGenomics/Equipment ParkProteomicsBiological Research FacilityFull details An optimized protocol for ChIP-Seq from human embryonic stem cell cultures Authors (2)Adrienne SullivanSilvia Santos STAR Protocols Published 17 July 2020 Crick labs/ facilitiesSilvia SantosAdvanced SequencingBioinformatics and BiostatisticsFull details Combined targeting of G protein-coupled receptor and EGF receptor signaling overcomes resistance to PI3K pathway inhibitors in PTEN-null triple negative breast cancer Authors (7)Davide ZecchinChristopher Moore Fanourios Michailidis Stuart HorswellSareena RanaMichael HowellJulian Downward EMBO Molecular Medicine Published 16 July 2020 Crick labs/ facilitiesJulian DownwardBioinformatics and BiostatisticsHigh Throughput ScreeningAdvanced SequencingCell ServicesExperimental HistopathologyGenomics/Equipment ParkBiological Research FacilityFull details Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers Authors (341) Catherine F Houlihan Nina Vora Thomas Byrne Dan Lewer Gavin Kelly Judith Heaney[...] Andrew Hayward Richard Gilson Gavin KellyFiona Roberts Emine Hatipoglu The Lancet Published 25 July 2020 Crick labs/ facilitiesLuiz Pedro CarvalhoMike BlackmanDominique BonnetPeter Cherepanov Steve GamblinMaximiliano GutierrezGeorge KassiotisPaul NurseAnne O’GarraVenizelos PapayannopoulosLucia Prieto-GodinoPeter RatcliffeCaetano Reis e SousaErik SahaiCharles SwantonMoritz TreeckJames TurnerJernej UleKaren VousdenAndreas WackSonia GandhiRupert BealeAdam SaterialeAdvanced SequencingCell ServicesBioinformatics and BiostatisticsElectron MicroscopyExperimental HistopathologyFlow CytometryGenomics/Equipment ParkHigh Throughput ScreeningMetabolomicsPeptide ChemistryStructural BiologyFermentationWorldwide Influenza CentreHuman Embryonic Stem CellScientific computingFull details Restriction of memory B cell differentiation at the germinal center B cell positive selection stage Authors (13) Amparo Toboso-Navasa Arief Gunawan Giulia Morlino Rinako Nakagawa Andrea Taddei Djamil Damry[...] Martin JanzGeorge Kassiotis Robert Brink Martin EilersDinis Calado Journal of Experimental Medicine Published 6 July 2020 Crick labs/ facilitiesDinis CaladoGeorge KassiotisBioinformatics and BiostatisticsAdvanced SequencingLight MicroscopyExperimental HistopathologyFlow CytometryBiological Research FacilityFull details CARD14E138A signalling in keratinocytes induces TNF-dependent skin and systemic inflammation Authors (7)Joan Manils Louise V WebbAshleigh Howes Julia Janzen Stefan Boeing Anne M BowcockSteve Ley eLife Published 29 June 2020 Crick labs/ facilitiesBioinformatics and BiostatisticsAdvanced SequencingExperimental HistopathologyFlow CytometryBiological Research FacilityFull details The transcription co-repressors MTG8 and MTG16 regulate exit of intestinal stem cells from their niche and differentiation into enterocyte vs secretory lineages Authors (11)Anna Baulies DomenechNikos Angelis Valentina FoglizzoE. Thomas Danielsen Harshil PatelLaura Novellasdemunt VilasecaAnia KucharskaJoana Do Vale Viegas Silva CarvalhoEmma Nye Paolo De CoppiVivian Li Gastroenterology Published 15 June 2020 Crick labs/ facilitiesVivian LiBioinformatics and BiostatisticsExperimental HistopathologyFull details Evidence that STK19 is not an NRAS-dependent melanoma driver Authors (11) Marta Rodríguez-Martínez Thierry Boissiére Melvin Noe GonzalezKevin Litchfield Richard MitterJane Walker Svend KjœrSoly IsmailJulian DownwardCharles SwantonJesper Svejstrup Cell Published 11 June 2020 Crick labs/ facilitiesJulian DownwardJesper SvejstrupCharles SwantonBioinformatics and BiostatisticsStructural BiologyCell ServicesProteomicsFull details Type I and III interferons disrupt lung epithelial repair during recovery from viral infection Authors (8)Jack MajorStefania Crotta Miriam Llorian Teresa M McCabe Hans Henrik Gad Simon L Priestnall Rune HartmannAndreas Wack Science Published 11 June 2020 Crick labs/ facilitiesAndreas WackBioinformatics and BiostatisticsExperimental HistopathologyFlow CytometryBiological Research FacilityFull details Development of a cell-free split-luciferase biochemical assay as a tool for screening for inhibitors of challenging protein-protein interaction targets Authors (11) Rachel Cooley Neesha Kara Ning Sze Hui Jonathan TartChloe RoustanRoger GeorgeDavid Hancock Brock F Binkowski Keith V WoodSoly IsmailJulian Downward Wellcome Open Research Published 2 June 2020 Crick labs/ facilitiesJulian DownwardStructural BiologyCell ServicesBioinformatics and BiostatisticsGenomics/Equipment ParkFull details Pagination Current page 1 Page 2 Page 3 Page 4 Page 5 Page 6 Page 7 Page 8 Page 9 … Next page Next Last page Last Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Butyrophilin-like proteins display combinatorial diversity in selecting and maintaining signature intraepithelial γδ T cell compartments Authors (12) Anett Jandke Daisy Melandri Leticia Monin Dmitry S Ushakov Adam G Laing Pierre Vantourout[...] Takeshi Nitta Tomoya Narita Hiroshi Takayanagi Regina FeederleAdrian Hayday Nature Communications Published 28 July 2020 Crick labs/ facilitiesAdrian HaydayBioinformatics and BiostatisticsCell ServicesExperimental HistopathologyFlow CytometryGenomics/Equipment ParkProteomicsBiological Research FacilityFull details
An optimized protocol for ChIP-Seq from human embryonic stem cell cultures Authors (2)Adrienne SullivanSilvia Santos STAR Protocols Published 17 July 2020 Crick labs/ facilitiesSilvia SantosAdvanced SequencingBioinformatics and BiostatisticsFull details
Combined targeting of G protein-coupled receptor and EGF receptor signaling overcomes resistance to PI3K pathway inhibitors in PTEN-null triple negative breast cancer Authors (7)Davide ZecchinChristopher Moore Fanourios Michailidis Stuart HorswellSareena RanaMichael HowellJulian Downward EMBO Molecular Medicine Published 16 July 2020 Crick labs/ facilitiesJulian DownwardBioinformatics and BiostatisticsHigh Throughput ScreeningAdvanced SequencingCell ServicesExperimental HistopathologyGenomics/Equipment ParkBiological Research FacilityFull details
Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers Authors (341) Catherine F Houlihan Nina Vora Thomas Byrne Dan Lewer Gavin Kelly Judith Heaney[...] Andrew Hayward Richard Gilson Gavin KellyFiona Roberts Emine Hatipoglu The Lancet Published 25 July 2020 Crick labs/ facilitiesLuiz Pedro CarvalhoMike BlackmanDominique BonnetPeter Cherepanov Steve GamblinMaximiliano GutierrezGeorge KassiotisPaul NurseAnne O’GarraVenizelos PapayannopoulosLucia Prieto-GodinoPeter RatcliffeCaetano Reis e SousaErik SahaiCharles SwantonMoritz TreeckJames TurnerJernej UleKaren VousdenAndreas WackSonia GandhiRupert BealeAdam SaterialeAdvanced SequencingCell ServicesBioinformatics and BiostatisticsElectron MicroscopyExperimental HistopathologyFlow CytometryGenomics/Equipment ParkHigh Throughput ScreeningMetabolomicsPeptide ChemistryStructural BiologyFermentationWorldwide Influenza CentreHuman Embryonic Stem CellScientific computingFull details
Restriction of memory B cell differentiation at the germinal center B cell positive selection stage Authors (13) Amparo Toboso-Navasa Arief Gunawan Giulia Morlino Rinako Nakagawa Andrea Taddei Djamil Damry[...] Martin JanzGeorge Kassiotis Robert Brink Martin EilersDinis Calado Journal of Experimental Medicine Published 6 July 2020 Crick labs/ facilitiesDinis CaladoGeorge KassiotisBioinformatics and BiostatisticsAdvanced SequencingLight MicroscopyExperimental HistopathologyFlow CytometryBiological Research FacilityFull details
CARD14E138A signalling in keratinocytes induces TNF-dependent skin and systemic inflammation Authors (7)Joan Manils Louise V WebbAshleigh Howes Julia Janzen Stefan Boeing Anne M BowcockSteve Ley eLife Published 29 June 2020 Crick labs/ facilitiesBioinformatics and BiostatisticsAdvanced SequencingExperimental HistopathologyFlow CytometryBiological Research FacilityFull details
The transcription co-repressors MTG8 and MTG16 regulate exit of intestinal stem cells from their niche and differentiation into enterocyte vs secretory lineages Authors (11)Anna Baulies DomenechNikos Angelis Valentina FoglizzoE. Thomas Danielsen Harshil PatelLaura Novellasdemunt VilasecaAnia KucharskaJoana Do Vale Viegas Silva CarvalhoEmma Nye Paolo De CoppiVivian Li Gastroenterology Published 15 June 2020 Crick labs/ facilitiesVivian LiBioinformatics and BiostatisticsExperimental HistopathologyFull details
Evidence that STK19 is not an NRAS-dependent melanoma driver Authors (11) Marta Rodríguez-Martínez Thierry Boissiére Melvin Noe GonzalezKevin Litchfield Richard MitterJane Walker Svend KjœrSoly IsmailJulian DownwardCharles SwantonJesper Svejstrup Cell Published 11 June 2020 Crick labs/ facilitiesJulian DownwardJesper SvejstrupCharles SwantonBioinformatics and BiostatisticsStructural BiologyCell ServicesProteomicsFull details
Type I and III interferons disrupt lung epithelial repair during recovery from viral infection Authors (8)Jack MajorStefania Crotta Miriam Llorian Teresa M McCabe Hans Henrik Gad Simon L Priestnall Rune HartmannAndreas Wack Science Published 11 June 2020 Crick labs/ facilitiesAndreas WackBioinformatics and BiostatisticsExperimental HistopathologyFlow CytometryBiological Research FacilityFull details
Development of a cell-free split-luciferase biochemical assay as a tool for screening for inhibitors of challenging protein-protein interaction targets Authors (11) Rachel Cooley Neesha Kara Ning Sze Hui Jonathan TartChloe RoustanRoger GeorgeDavid Hancock Brock F Binkowski Keith V WoodSoly IsmailJulian Downward Wellcome Open Research Published 2 June 2020 Crick labs/ facilitiesJulian DownwardStructural BiologyCell ServicesBioinformatics and BiostatisticsGenomics/Equipment ParkFull details
