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Breadcrumb Bioinformatics and Biostatistics Bioinformatics and Biostatistics : Publications Lab contentLab contentIn this section Overview Publications Members Bioinformatic visualisation of protein binding along a human chromosome, courtesy of Federico Agostini and Nick Luscombe. Toggle to view hero caption Publications Displaying 1 - 10 of 424Last updated : 29 September 2023 03:06 A branching model of lineage differentiation underpinning the neurogenic potential of enteric glia Authors (15) Anna LaddachSong Hui ChngReena LasradoFranze ProgatzkyMichael Shapiro Alek Erickson[...] Jens Kleinjung Stefan BoeingSila Ultanir Igor AdameykoVassilis Pachnis Nature Communications Published 22 September 2023 Crick labs/ facilitiesSila UltanirVassilis PachnisBioinformatics and BiostatisticsFlow CytometryBiological Research FacilityAdvanced SequencingFull details Conserved γδ T cell selection by BTNL proteins limits progression of human inflammatory bowel disease Authors (14) Robin J Dart Iva Zlatareva Pierre Vantourout Efstathios Theodoridis Ariella Amar Shichina Kannambath[...] Christopher A Lamb Miles Parkes Peter M Irving Natalie J PrescottAdrian Hayday Science Published 15 September 2023 Crick labs/ facilitiesAdrian HaydayBioinformatics and BiostatisticsAdvanced SequencingFull details Mosaic BRAF fusions are a recurrent cause of congenital melanocytic naevi targetable by MEK inhibition Authors (18) Sara Barberan Martin Satyamaanasa PolubothuAlicia BruzosGavin Kelly Stuart HorswellAimie Sauvadet[...] Nicole Knöpfel Neil Bulstrode Alan Pittman Iwei YehVeronica Kinsler Journal of Investigative Dermatology Published 15 September 2023 Crick labs/ facilitiesVeronica KinslerBioinformatics and BiostatisticsFull details DNA-directed termination of RNA polymerase II transcription Authors (8) Zhong Han George A Moore Richard Mitter David Lopez MartinezLi Wan A Barbara Dirac Svejstrup David S RuedaJesper Svejstrup Molecular Cell Published 21 September 2023 Crick labs/ facilitiesJesper SvejstrupBioinformatics and BiostatisticsFermentationAdvanced SequencingFull details The master energy homeostasis regulator PGC-1α exhibits an mRNA nuclear export function Authors (16)Simeon Mihaylov Lydia M Castelli Ya-Hui Lin Aytac Gül Nikita Soni Christopher Hastings[...] Oliver Bandmann Tatyana A Shelkovnikova Heather MortiboysSila Ultanir Guillaume M Hautbergue Nature Communications Published 7 September 2023 Crick labs/ facilitiesSila UltanirFrancois GuillemotProteomicsBioinformatics and BiostatisticsFull details Defining the identity and the niches of epithelial stem cells with highly pleiotropic multilineage potency in the human thymus Authors (17)Roberta Ragazzini Stefan BoeingLuca ZanieriMary Green Giuseppe D’Agostino Kerol Bartolovic[...] David Scoville Andy NamAdrian HaydayDominique BonnetPaola Bonfanti Developmental Cell Published 30 August 2023 Crick labs/ facilitiesAdrian HaydayDominique BonnetPaola BonfantiFlow CytometryExperimental HistopathologyBioinformatics and BiostatisticsLight MicroscopyAdvanced SequencingFull details Endothelial AHR activity prevents lung barrier disruption in viral infection Authors (13)Jack MajorStefania CrottaKatja Finsterbusch Probir ChakravartyKathleen ShahBruno Goncalves Frederico[...] Lucy Meader Alejandro Suarez-BonnetSimon PriestnallBrigitta StockingerAndreas Wack Nature Published 16 August 2023 Crick labs/ facilitiesAndreas WackGitta StockingerCaetano Reis e SousaLight MicroscopyExperimental HistopathologyBioinformatics and BiostatisticsFlow CytometryBiological Research FacilityAdvanced SequencingFull details Interferon-g-dependent interactions between tissue-intrinsic γδ T cells and tissue-infiltrating CD8 T cells limit acute contact dermatitis Authors (15)Miguel Munoz-Ruiz Miriam LlorianRocco D'Antuono Anna Pavlova Anna Maria MavrigiannakiDuncan McKenzie[...] Daniel Davies Mariam Jamal-Hanjani Anett Jandke Dmitry S UshakovAdrian Hayday Journal of Allergy and Clinical Immunology Published 8 August 2023 Crick labs/ facilitiesVassilis PachnisAdrian HaydayLight MicroscopyBioinformatics and BiostatisticsFull details Gastruloid-derived primordial germ cell-like cells develop dynamically within integrated tissues Authors (5) Christopher B Cooke Christopher BarringtonPeter Baillie-Benson Jennifer NicholsNaomi Moris Development Published 1 September 2023 Crick labs/ facilitiesNaomi MorisBioinformatics and BiostatisticsLight MicroscopyFlow CytometryAdvanced SequencingFull details The transcriptional landscape of endogenous retroelements delineates esophageal adenocarcinoma subtypes Authors (11)Anastasiya KazachenkaJane LoongJan AttigGeorge YoungPiyali Ganguli Ginny Devonshire Nicola Grehan The OCCAMS ConsortiumFrancesca Ciccarelli Rebecca C FitzgeraldGeorge Kassiotis NAR Cancer Published 1 September 2023 Crick labs/ facilitiesGeorge KassiotisFrancesca CiccarelliBioinformatics and BiostatisticsScientific computingCell ServicesAdvanced SequencingFull details Pagination Current page 1 Page 2 Page 3 Page 4 Page 5 Page 6 Page 7 Page 8 Page 9 … Next page Next Last page Last Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
A branching model of lineage differentiation underpinning the neurogenic potential of enteric glia Authors (15) Anna LaddachSong Hui ChngReena LasradoFranze ProgatzkyMichael Shapiro Alek Erickson[...] Jens Kleinjung Stefan BoeingSila Ultanir Igor AdameykoVassilis Pachnis Nature Communications Published 22 September 2023 Crick labs/ facilitiesSila UltanirVassilis PachnisBioinformatics and BiostatisticsFlow CytometryBiological Research FacilityAdvanced SequencingFull details
Conserved γδ T cell selection by BTNL proteins limits progression of human inflammatory bowel disease Authors (14) Robin J Dart Iva Zlatareva Pierre Vantourout Efstathios Theodoridis Ariella Amar Shichina Kannambath[...] Christopher A Lamb Miles Parkes Peter M Irving Natalie J PrescottAdrian Hayday Science Published 15 September 2023 Crick labs/ facilitiesAdrian HaydayBioinformatics and BiostatisticsAdvanced SequencingFull details
Mosaic BRAF fusions are a recurrent cause of congenital melanocytic naevi targetable by MEK inhibition Authors (18) Sara Barberan Martin Satyamaanasa PolubothuAlicia BruzosGavin Kelly Stuart HorswellAimie Sauvadet[...] Nicole Knöpfel Neil Bulstrode Alan Pittman Iwei YehVeronica Kinsler Journal of Investigative Dermatology Published 15 September 2023 Crick labs/ facilitiesVeronica KinslerBioinformatics and BiostatisticsFull details
DNA-directed termination of RNA polymerase II transcription Authors (8) Zhong Han George A Moore Richard Mitter David Lopez MartinezLi Wan A Barbara Dirac Svejstrup David S RuedaJesper Svejstrup Molecular Cell Published 21 September 2023 Crick labs/ facilitiesJesper SvejstrupBioinformatics and BiostatisticsFermentationAdvanced SequencingFull details
The master energy homeostasis regulator PGC-1α exhibits an mRNA nuclear export function Authors (16)Simeon Mihaylov Lydia M Castelli Ya-Hui Lin Aytac Gül Nikita Soni Christopher Hastings[...] Oliver Bandmann Tatyana A Shelkovnikova Heather MortiboysSila Ultanir Guillaume M Hautbergue Nature Communications Published 7 September 2023 Crick labs/ facilitiesSila UltanirFrancois GuillemotProteomicsBioinformatics and BiostatisticsFull details
Defining the identity and the niches of epithelial stem cells with highly pleiotropic multilineage potency in the human thymus Authors (17)Roberta Ragazzini Stefan BoeingLuca ZanieriMary Green Giuseppe D’Agostino Kerol Bartolovic[...] David Scoville Andy NamAdrian HaydayDominique BonnetPaola Bonfanti Developmental Cell Published 30 August 2023 Crick labs/ facilitiesAdrian HaydayDominique BonnetPaola BonfantiFlow CytometryExperimental HistopathologyBioinformatics and BiostatisticsLight MicroscopyAdvanced SequencingFull details
Endothelial AHR activity prevents lung barrier disruption in viral infection Authors (13)Jack MajorStefania CrottaKatja Finsterbusch Probir ChakravartyKathleen ShahBruno Goncalves Frederico[...] Lucy Meader Alejandro Suarez-BonnetSimon PriestnallBrigitta StockingerAndreas Wack Nature Published 16 August 2023 Crick labs/ facilitiesAndreas WackGitta StockingerCaetano Reis e SousaLight MicroscopyExperimental HistopathologyBioinformatics and BiostatisticsFlow CytometryBiological Research FacilityAdvanced SequencingFull details
Interferon-g-dependent interactions between tissue-intrinsic γδ T cells and tissue-infiltrating CD8 T cells limit acute contact dermatitis Authors (15)Miguel Munoz-Ruiz Miriam LlorianRocco D'Antuono Anna Pavlova Anna Maria MavrigiannakiDuncan McKenzie[...] Daniel Davies Mariam Jamal-Hanjani Anett Jandke Dmitry S UshakovAdrian Hayday Journal of Allergy and Clinical Immunology Published 8 August 2023 Crick labs/ facilitiesVassilis PachnisAdrian HaydayLight MicroscopyBioinformatics and BiostatisticsFull details
Gastruloid-derived primordial germ cell-like cells develop dynamically within integrated tissues Authors (5) Christopher B Cooke Christopher BarringtonPeter Baillie-Benson Jennifer NicholsNaomi Moris Development Published 1 September 2023 Crick labs/ facilitiesNaomi MorisBioinformatics and BiostatisticsLight MicroscopyFlow CytometryAdvanced SequencingFull details
The transcriptional landscape of endogenous retroelements delineates esophageal adenocarcinoma subtypes Authors (11)Anastasiya KazachenkaJane LoongJan AttigGeorge YoungPiyali Ganguli Ginny Devonshire Nicola Grehan The OCCAMS ConsortiumFrancesca Ciccarelli Rebecca C FitzgeraldGeorge Kassiotis NAR Cancer Published 1 September 2023 Crick labs/ facilitiesGeorge KassiotisFrancesca CiccarelliBioinformatics and BiostatisticsScientific computingCell ServicesAdvanced SequencingFull details
