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Bioinformatics and Biostatistics : Publications

Publications

Macpherson,Jamie A; Theisen,Alina; Masino,Laura; Fets,Louise; Driscoll,Paul C; Encheva,Vesela; et al

Functional cross-talk between allosteric effects of activating and inhibiting ligands underlies PKM2 regulation.

Elife (2019) 8, Epub ahead of print

Bradley,Konrad C; Finsterbusch,Katja; Schnepf,Daniel; Crotta,Stefania; Llorian,Miriam; Davidson,Sophia; et al

Microbiota-driven tonic interferon signals in lung stromal cells protect from influenza virus infection.

Cell Reports (2019) 28, 245-256.e4

Sellers,Katherine; Allen,Thaddeus D; Bousamra,Michael; Tan,JinLian; Méndez-Lucas,Andrés; Lin,Wei; et al

Metabolic reprogramming and Notch activity distinguish between non-small cell lung cancer subtypes.

British Journal of Cancer (2019) 121, 51-64

Singhania,Akul; Graham,Christine M; Gabryšová,Leona; Moreira-Teixeira,Lúcia; Stavropoulos,Evangelos; Pitt,Jonathan M; et al

Transcriptional profiling unveils type I and II interferon networks in blood and tissues across diseases.

Nature Communications (2019) 10, 2887

Omenetti,Sara; Bussi,Claudio; Metidji,Amina; Iseppon,Andrea; Lee,Sunjae; Tolaini,Mauro; et al

The intestine harbors functionally distinct homeostatic tissue-resident and inflammatory Th17 cells.

Immunity (2019) 51, Epub ahead of print

Muñoz,Sofía; Minamino,Masashi; Casas-Delucchi,Corella S; Patel,Harshil; Uhlmann,Frank

A role for chromatin remodeling in cohesin loading onto chromosomes

Molecular Cell (2019) 74, 664-673.e5

Diring,Jessica; Mouilleron,Stephane; McDonald,Neil Q; Treisman,Richard

RPEL-family rhoGAPs link Rac/Cdc42 GTP loading to G-actin availability.

Nature Cell Biology (2019) 21, 845-855

Greenwood,Daniel J; Dos Santos,Mariana Silva; Huang,Song; Russell,Matthew RG; Collinson,Lucy M; MacRae,James I; et al

Subcellular antibiotic visualization reveals a dynamic drug reservoir in infected macrophages.

Science (2019) 364, 1279-1282

Burnham,Daniel R; Kose,Hazal B; Hoyle,Rebecca B; Yardimci,Hasan

The mechanism of DNA unwinding by the eukaryotic replicative helicase.

Nature Communications (2019) 10, 2159

Wallbank,Bethan A; Dominicus,Caia S; Broncel,Malgorzata; Legrave,Nathalie; MacRae,James I; Staines,Henry M; et al

Characterisation of the Toxoplasma gondii tyrosine transporter and its phosphorylation by the calcium-dependent protein kinase 3

Molecular Microbiology (2019) 111, 1167-1181

Chakrabarti,Anob M; Henser-Brownhill,Tristan; Monserrat,Josep; Poetsch,Anna R; Luscombe,Nicholas M; Scaffidi,Paola

Target-specific precision of CRISPR-mediated genome editing

Molecular Cell (2019) 73, 699-713.e6

Poetsch,Anna R; Boulton,Simon J; Luscombe,Nicholas M

Genomic landscape of oxidative DNA damage and repair reveals regioselective protection from mutagenesis

Genome Biology (2018) 19, 215