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Bioinformatics and Biostatistics : Publications

Publications

Touati,Sandra A; Hofbauer,Lorena; Jones,Andrew W; Snijders,Ambrosius P; Kelly,Gavin; Uhlmann,Frank

Cdc14 and PP2A phosphatases cooperate to shape phosphoproteome dynamics during mitotic exit.

Cell Reports (2019) 29, 2105-2119.e4

Zatreanu,Diana; Han,Zhong; Mitter,Richard; Tumini,Emanuela; Williams,Hannah; Gregersen,Lea; et al

Elongation factor TFIIS prevents transcription stress and R-loop accumulation to maintain genome stability

Molecular Cell (2019) 76, 57-69.e9

Molina-Arcas,Miriam; Moore,Christopher; Rana,Sareena; van Maldegem,Febe; Mugarza,Edurne; Romero-Clavijo,Pablo; et al

Development of combination therapies to maximize the impact of KRAS-G12C inhibitors in lung cancer

Science Translational Medicine (2019) 11, eaaw7999

Young,Joanna; Dominicus,Caia; Wagener,Jeanette; Butterworth,Simon; Ye,Xingda; Kelly,Gavin; et al

A CRISPR platform for targeted in vivo screens identifies Toxoplasma gondii virulence factors in mice.

Nature Communications (2019) 10, 3963

Ombrato,Luigi; Nolan,Emma; Kurelac,Ivana; Mavousian,Antranik; Bridgeman,Victoria Louise; Heinze,Ivonne; et al

Metastatic-niche labelling reveals parenchymal cells with stem features.

Nature (2019) 572, 603-608

Rohlwink,Ursula K; Figaji,Anthony; Wilkinson,Katalin A; Horswell,Stuart; Sesay,Abdul K; Deffur,Armin; et al

Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity.

Nature Communications (2019) 10, 3767

Wershof,Esther; Park,Danielle; Jenkins,Robert P; Barry,David J; Sahai,Erik; Bates,Paul A

Matrix feedback enables diverse higher-order patterning of the extracellular matrix.

PLoS Computational Biology (2019) 15, e1007251

Blomfield,Isabelle M; Rocamonde,Brenda; Masdeu,Maria Del Mar; Mulugeta,Eskeatnaf; Vaga,Stefania; van den Berg,Debbie LC; et al

Id4 promotes the elimination of the pro-activation factor Ascl1 to maintain quiescence of adult hippocampal stem cells.

Elife (2019) 8, Epub ahead of print

Diring,Jessica; Mouilleron,Stephane; McDonald,Neil Q; Treisman,Richard

RPEL-family rhoGAPs link Rac/Cdc42 GTP loading to G-actin availability.

Nature Cell Biology (2019) 21, 845-855

Greenwood,Daniel J; Dos Santos,Mariana Silva; Huang,Song; Russell,Matthew RG; Collinson,Lucy M; MacRae,James I; et al

Subcellular antibiotic visualization reveals a dynamic drug reservoir in infected macrophages.

Science (2019) 364, 1279-1282

Burnham,Daniel R; Kose,Hazal B; Hoyle,Rebecca B; Yardimci,Hasan

The mechanism of DNA unwinding by the eukaryotic replicative helicase.

Nature Communications (2019) 10, 2159

Wallbank,Bethan A; Dominicus,Caia S; Broncel,Malgorzata; Legrave,Nathalie; MacRae,James I; Staines,Henry M; et al

Characterisation of the Toxoplasma gondii tyrosine transporter and its phosphorylation by the calcium-dependent protein kinase 3

Molecular Microbiology (2019) 111, 1167-1181