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Breadcrumb Bioinformatics and Biostatistics Bioinformatics and Biostatistics : Publications Lab contentLab contentIn this section Overview Publications Members Bioinformatic visualisation of protein binding along a human chromosome, courtesy of Federico Agostini and Nick Luscombe. Toggle to view hero caption Publications Displaying 11 - 20 of 444Last updated : 17 April 2024 03:06 Detection of chromosomal aneuploidy in ancient genomes Authors (31)Kyriaki AnastasiadouMarina Soares Da SilvaThomas BoothLeo Speidel Tony Audsley Christopher Barrington[...] Malin Holst Louise Loe Ian Armit Rick SchultingPontus Skoglund Communications Biology Published 11 January 2024 Crick labs/ facilitiesPontus SkoglundBioinformatics and BiostatisticsAdvanced SequencingFull details The artificial intelligence-based model ANORAK improves histopathological grading of lung adenocarcinoma Authors (20) Xiaoxi Pan Khalid AbdulJabbar Jose Coelho-Lima Anca-Ioana Grapa Hanyun Zhang Alvin Ho Kwan Cheung[...] TRACERx ConsortiumCharles Swanton Yinyin Yuan John Le Quesne David A Moore Nature Cancer Published 1 February 2024 Crick labs/ facilitiesPeter Van LooSamra TurajlicCharles SwantonErik SahaiGeorge KassiotisFlow CytometryExperimental HistopathologyBiological Research FacilityBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details Perlecan (HSPG2) promotes structural, contractile, and metabolic development of human cardiomyocytes Authors (18) Benjamin B Johnson Marie-Victoire CossonLorenza Iolanda Tsansizi Terri L HolmesTegan Gilmore Katherine Hampton[...] John Whitelock Linda Troeberg Stuart A Rushworth Andreia S Bernardo James GW Smith Cell Reports Published 23 January 2024 Crick labs/ facilitiesJim SmithHigh Throughput ScreeningBioinformatics and BiostatisticsStructural BiologyMaking LabAdvanced SequencingFull details An individual with Sarmatian-related ancestry in Roman Britain Authors (14)Marina Soares Da SilvaThomas Booth Joanna MooreKyriaki Anastasiadou Don WalkerAlexandre Gilardet[...] Michael Henderson Alex Smith David Bowsher Janet MontgomeryPontus Skoglund Current Biology Published 8 January 2024 Crick labs/ facilitiesPontus SkoglundBioinformatics and BiostatisticsScientific computingAdvanced SequencingFull details T cell migration requires ion and water influx to regulate actin polymerization Authors (13)Leon De BoerLesley Vanes Serena MelgratiJoshua Biggs O'MayDarryl HaywardPaul Driscoll[...] Renata Magueta Alexander MorrellJames MacraeRobert KoechlVictor Tybulewicz Nature Communications Published 6 December 2023 Crick labs/ facilitiesVictor TybulewiczMetabolomicsLight MicroscopyFlow CytometryBiological Research FacilityBioinformatics and BiostatisticsFull details The -KTS splice variant of WT1 is essential for ovarian determination in mice Authors (20) Elodie P Gregoire Marie-Cécile De CianRoberta Migale Aitana Perea-Gomez Sébastien Schaub Natividad Bellido-Carreras[...]Robin Lovell-Badge Serge Nef Frédéric Chalmel Andreas Schedl Marie-Christine Chaboissier Science Published 3 November 2023 Crick labs/ facilitiesRobin Lovell-BadgeBioinformatics and BiostatisticsFlow CytometryBiological Research FacilityAdvanced SequencingFull details Circulating neutrophils from patients with early breast cancer have distinct subtype-dependent phenotypes Authors (9)Anisha Ramessur Bana AmbasagerIker Valle AramburuFrederick Peakman Kelly Gleason Christoph LehmannVenizelos Papayannopoulos Raoul Charles CoombesIlaria Malanchi Breast Cancer Research Published 19 October 2023 Crick labs/ facilitiesVenizelos PapayannopoulosIlaria MalanchiFlow CytometryBiological Research FacilityBioinformatics and BiostatisticsFull details Establishment of dsDNA-dsDNA interactions by the condensin complex Authors (8)Tony TangGeorge Pobegalov Hideki Tanizawa Zhuo A Chen Juri RappsilberMaxim Molodtsov Ken-ichi NomaFrank Uhlmann Molecular Cell Published 1 November 2023 Crick labs/ facilitiesFrank UhlmannMaxim MolodtsovFermentationBioinformatics and BiostatisticsFull details Hormone-mediated neural remodeling orchestrates parenting onset during pregnancy Authors (10)Rachida AmmariFrancesco MonacaMingran CaoEstelle NassarPatty Wai Nicholas A Del Grosso Matthew LeeNeven BorakDeborah Schneider-LuftmanJonny Kohl Science Published 6 October 2023 Crick labs/ facilitiesJohannes KohlBioinformatics and BiostatisticsMaking LabLight MicroscopyGenetic Modification ServiceExperimental HistopathologyBiological Research FacilityFull details SOX9-positive pituitary stem cells differ according to their position in the gland and maintenance of their progeny depends on context Authors (4)Karine Rizzoti Probir ChakravartyDaniel SheridanRobin Lovell-Badge Science advances Published 4 October 2023 Crick labs/ facilitiesRobin Lovell-BadgeBioinformatics and BiostatisticsLight MicroscopyExperimental HistopathologyBiological Research FacilityAdvanced SequencingFull details Pagination First page First Previous page Previous Page 1 Current page 2 Page 3 Page 4 Page 5 Page 6 Page 7 Page 8 Page 9 … Next page Next Last page Last Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Detection of chromosomal aneuploidy in ancient genomes Authors (31)Kyriaki AnastasiadouMarina Soares Da SilvaThomas BoothLeo Speidel Tony Audsley Christopher Barrington[...] Malin Holst Louise Loe Ian Armit Rick SchultingPontus Skoglund Communications Biology Published 11 January 2024 Crick labs/ facilitiesPontus SkoglundBioinformatics and BiostatisticsAdvanced SequencingFull details
The artificial intelligence-based model ANORAK improves histopathological grading of lung adenocarcinoma Authors (20) Xiaoxi Pan Khalid AbdulJabbar Jose Coelho-Lima Anca-Ioana Grapa Hanyun Zhang Alvin Ho Kwan Cheung[...] TRACERx ConsortiumCharles Swanton Yinyin Yuan John Le Quesne David A Moore Nature Cancer Published 1 February 2024 Crick labs/ facilitiesPeter Van LooSamra TurajlicCharles SwantonErik SahaiGeorge KassiotisFlow CytometryExperimental HistopathologyBiological Research FacilityBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details
Perlecan (HSPG2) promotes structural, contractile, and metabolic development of human cardiomyocytes Authors (18) Benjamin B Johnson Marie-Victoire CossonLorenza Iolanda Tsansizi Terri L HolmesTegan Gilmore Katherine Hampton[...] John Whitelock Linda Troeberg Stuart A Rushworth Andreia S Bernardo James GW Smith Cell Reports Published 23 January 2024 Crick labs/ facilitiesJim SmithHigh Throughput ScreeningBioinformatics and BiostatisticsStructural BiologyMaking LabAdvanced SequencingFull details
An individual with Sarmatian-related ancestry in Roman Britain Authors (14)Marina Soares Da SilvaThomas Booth Joanna MooreKyriaki Anastasiadou Don WalkerAlexandre Gilardet[...] Michael Henderson Alex Smith David Bowsher Janet MontgomeryPontus Skoglund Current Biology Published 8 January 2024 Crick labs/ facilitiesPontus SkoglundBioinformatics and BiostatisticsScientific computingAdvanced SequencingFull details
T cell migration requires ion and water influx to regulate actin polymerization Authors (13)Leon De BoerLesley Vanes Serena MelgratiJoshua Biggs O'MayDarryl HaywardPaul Driscoll[...] Renata Magueta Alexander MorrellJames MacraeRobert KoechlVictor Tybulewicz Nature Communications Published 6 December 2023 Crick labs/ facilitiesVictor TybulewiczMetabolomicsLight MicroscopyFlow CytometryBiological Research FacilityBioinformatics and BiostatisticsFull details
The -KTS splice variant of WT1 is essential for ovarian determination in mice Authors (20) Elodie P Gregoire Marie-Cécile De CianRoberta Migale Aitana Perea-Gomez Sébastien Schaub Natividad Bellido-Carreras[...]Robin Lovell-Badge Serge Nef Frédéric Chalmel Andreas Schedl Marie-Christine Chaboissier Science Published 3 November 2023 Crick labs/ facilitiesRobin Lovell-BadgeBioinformatics and BiostatisticsFlow CytometryBiological Research FacilityAdvanced SequencingFull details
Circulating neutrophils from patients with early breast cancer have distinct subtype-dependent phenotypes Authors (9)Anisha Ramessur Bana AmbasagerIker Valle AramburuFrederick Peakman Kelly Gleason Christoph LehmannVenizelos Papayannopoulos Raoul Charles CoombesIlaria Malanchi Breast Cancer Research Published 19 October 2023 Crick labs/ facilitiesVenizelos PapayannopoulosIlaria MalanchiFlow CytometryBiological Research FacilityBioinformatics and BiostatisticsFull details
Establishment of dsDNA-dsDNA interactions by the condensin complex Authors (8)Tony TangGeorge Pobegalov Hideki Tanizawa Zhuo A Chen Juri RappsilberMaxim Molodtsov Ken-ichi NomaFrank Uhlmann Molecular Cell Published 1 November 2023 Crick labs/ facilitiesFrank UhlmannMaxim MolodtsovFermentationBioinformatics and BiostatisticsFull details
Hormone-mediated neural remodeling orchestrates parenting onset during pregnancy Authors (10)Rachida AmmariFrancesco MonacaMingran CaoEstelle NassarPatty Wai Nicholas A Del Grosso Matthew LeeNeven BorakDeborah Schneider-LuftmanJonny Kohl Science Published 6 October 2023 Crick labs/ facilitiesJohannes KohlBioinformatics and BiostatisticsMaking LabLight MicroscopyGenetic Modification ServiceExperimental HistopathologyBiological Research FacilityFull details
SOX9-positive pituitary stem cells differ according to their position in the gland and maintenance of their progeny depends on context Authors (4)Karine Rizzoti Probir ChakravartyDaniel SheridanRobin Lovell-Badge Science advances Published 4 October 2023 Crick labs/ facilitiesRobin Lovell-BadgeBioinformatics and BiostatisticsLight MicroscopyExperimental HistopathologyBiological Research FacilityAdvanced SequencingFull details