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Breadcrumb Bioinformatics and Biostatistics Bioinformatics and Biostatistics : Publications Lab contentLab contentIn this section Overview Publications Members Bioinformatic visualisation of protein binding along a human chromosome, courtesy of Federico Agostini and Nick Luscombe. Toggle to view hero caption Publications Displaying 41 - 50 of 445Last updated : 23 April 2024 02:05 Replisome-cohesin interactions provided by the Tof1-Csm3 and Mrc1 cohesion establishment factors Authors (6)Sudikchya ShresthaMasashi Minamino Zhuo A ChenCeline Bouchoux Juri RappsilberFrank Uhlmann Chromosoma Published 1 June 2023 Crick labs/ facilitiesFrank UhlmannFermentationBioinformatics and BiostatisticsFull details Generation of left ventricle-like cardiomyocytes with improved structural, functional, and metabolic maturity from human pluripotent stem cells Authors (18) Nicola Dark Marie-Victoire CossonLorenza Iolanda Tsansizi Thomas J Owen Elisa Ferraro Alice J Francis[...] Elisabeth Ehler Richard Mitter Sian E HardingJim Smith Andreia S Bernardo Cell Reports Methods Published 24 April 2023 Crick labs/ facilitiesJames TurnerJim SmithElectron MicroscopyBioinformatics and BiostatisticsFull details Integrated transcriptome landscape of ALS identifies genome instability linked to TDP-43 pathology Authors (14)Oliver ZiffJacob NeevesJamie MitchellGiulia Tyzack Carlos Martinez-Ruiz Raphaelle Luisier[...]Simon Boulton Ammar Al-ChalabiGavin Kelly Jack HumphreyRickie Patani Nature Communications Published 20 April 2023 Crick labs/ facilitiesJernej UleRickie PataniSimon BoultonBioinformatics and BiostatisticsScientific computingFull details Sotrovimab restores neutralization against current Omicron subvariants in patients with blood cancer Authors (67)Mary WuScott Shepherd Annika FendlerEdward CarrLewis Au Ruth Harvey[...] Emma Nicholson James Larkin Emma C WallSamra Turajlic CAPTURE consortium Cancer Cell Published 8 May 2023 Crick labs/ facilitiesSamra TurajlicCharles SwantonNicola LewisGeorge KassiotisSonia GandhiSteve GamblinRupert BealeDavid LV BauerWorldwide Influenza CentreMetabolomicsHigh Throughput ScreeningBioinformatics and BiostatisticsScientific computingFull details Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA Authors (55) Christopher AbboshAlexander Frankell Thomas Harrison Judit Kisistok Aaron Garnett Laura Johnson[...] Mariam Jamal-Hanjani TRACERx ConsortiumNicolai Birkbak Nicholas McGranahanCharles Swanton Nature Published 20 April 2023 Crick labs/ facilitiesPeter Van LooCharles SwantonGeorge KassiotisGerard EvanFlow CytometryExperimental HistopathologyBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details Antibodies against endogenous retroviruses promote lung cancer immunotherapy Authors (51)Kevin NgJesse BoumelhaKatey EnfieldJorge Almagro Hongui Cha Oriol Pich[...] Se-Hoon LeeSamra TurajlicCharles SwantonJulian DownwardGeorge Kassiotis Nature Published 20 April 2023 Crick labs/ facilitiesRobert J WilkinsonPeter Van LooSamra TurajlicCharles SwantonGeorge KassiotisJulian DownwardAxel BehrensFlow CytometryExperimental HistopathologyBioinformatics and BiostatisticsAdvanced SequencingScientific computingProteomicsLight MicroscopyCell ServicesBiological Research FacilityFull details Body composition and lung cancer-associated cachexia in TRACERx Authors (44)Othman Al-Sawaf Jakob Weiss Marcin Skrzypski Jie Min LamTakahiro Karasaki Francisco Zambrana[...]Nicolai Birkbak Hugo JWL Aerts TRACERx Consortium Mariam Jamal-HanjaniCharles Swanton Nature Medicine Published 1 April 2023 Crick labs/ facilitiesPeter Van LooCharles SwantonGeorge KassiotisFlow CytometryExperimental HistopathologyBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details Evolutionary characterization of lung adenocarcinoma morphology in TRACERx Authors (53)Takahiro Karasaki David A Moore Selvaraju Veeriah Cristina Naceur-Lombardelli Antonia Toncheva Neil Magno[...] Andrew G Nicholson TRACERx Consortium Nicholas McGranahanCharles Swanton Mariam Jamal-Hanjani Nature Medicine Published 1 April 2023 Crick labs/ facilitiesPeter Van LooCharles SwantonGeorge KassiotisFlow CytometryExperimental HistopathologyBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details Genomic-transcriptomic evolution in lung cancer and metastasis Authors (47) Carlos Martínez-Ruiz James RM Black Clare Puttick Mark S HillJonas DemeulemeesterElizabeth Larose Cadieux[...] Peter Van Loo Mariam Jamal-Hanjani TRACERx Consortium Charles Swanton Nicholas McGranahan Nature Published 20 April 2023 Crick labs/ facilitiesPeter Van LooCharles SwantonGeorge KassiotisJulian DownwardFlow CytometryExperimental HistopathologyBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details The evolution of lung cancer and impact of subclonal selection in TRACERx Authors (81)Alexander FrankellMichelle DietzenMaise Al BakirEmilia LimTakahiro KarasakiSophie Ward[...] Simone Zaccaria TRACERx Consortium Mariam Jamal-Hanjani Nicholas McGranahanCharles Swanton Nature Published 20 April 2023 Crick labs/ facilitiesPeter Van LooCharles SwantonGeorge KassiotisFlow CytometryExperimental HistopathologyBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details Pagination First page First Previous page Previous Page 1 Page 2 Page 3 Page 4 Current page 5 Page 6 Page 7 Page 8 Page 9 … Next page Next Last page Last Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Replisome-cohesin interactions provided by the Tof1-Csm3 and Mrc1 cohesion establishment factors Authors (6)Sudikchya ShresthaMasashi Minamino Zhuo A ChenCeline Bouchoux Juri RappsilberFrank Uhlmann Chromosoma Published 1 June 2023 Crick labs/ facilitiesFrank UhlmannFermentationBioinformatics and BiostatisticsFull details
Generation of left ventricle-like cardiomyocytes with improved structural, functional, and metabolic maturity from human pluripotent stem cells Authors (18) Nicola Dark Marie-Victoire CossonLorenza Iolanda Tsansizi Thomas J Owen Elisa Ferraro Alice J Francis[...] Elisabeth Ehler Richard Mitter Sian E HardingJim Smith Andreia S Bernardo Cell Reports Methods Published 24 April 2023 Crick labs/ facilitiesJames TurnerJim SmithElectron MicroscopyBioinformatics and BiostatisticsFull details
Integrated transcriptome landscape of ALS identifies genome instability linked to TDP-43 pathology Authors (14)Oliver ZiffJacob NeevesJamie MitchellGiulia Tyzack Carlos Martinez-Ruiz Raphaelle Luisier[...]Simon Boulton Ammar Al-ChalabiGavin Kelly Jack HumphreyRickie Patani Nature Communications Published 20 April 2023 Crick labs/ facilitiesJernej UleRickie PataniSimon BoultonBioinformatics and BiostatisticsScientific computingFull details
Sotrovimab restores neutralization against current Omicron subvariants in patients with blood cancer Authors (67)Mary WuScott Shepherd Annika FendlerEdward CarrLewis Au Ruth Harvey[...] Emma Nicholson James Larkin Emma C WallSamra Turajlic CAPTURE consortium Cancer Cell Published 8 May 2023 Crick labs/ facilitiesSamra TurajlicCharles SwantonNicola LewisGeorge KassiotisSonia GandhiSteve GamblinRupert BealeDavid LV BauerWorldwide Influenza CentreMetabolomicsHigh Throughput ScreeningBioinformatics and BiostatisticsScientific computingFull details
Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA Authors (55) Christopher AbboshAlexander Frankell Thomas Harrison Judit Kisistok Aaron Garnett Laura Johnson[...] Mariam Jamal-Hanjani TRACERx ConsortiumNicolai Birkbak Nicholas McGranahanCharles Swanton Nature Published 20 April 2023 Crick labs/ facilitiesPeter Van LooCharles SwantonGeorge KassiotisGerard EvanFlow CytometryExperimental HistopathologyBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details
Antibodies against endogenous retroviruses promote lung cancer immunotherapy Authors (51)Kevin NgJesse BoumelhaKatey EnfieldJorge Almagro Hongui Cha Oriol Pich[...] Se-Hoon LeeSamra TurajlicCharles SwantonJulian DownwardGeorge Kassiotis Nature Published 20 April 2023 Crick labs/ facilitiesRobert J WilkinsonPeter Van LooSamra TurajlicCharles SwantonGeorge KassiotisJulian DownwardAxel BehrensFlow CytometryExperimental HistopathologyBioinformatics and BiostatisticsAdvanced SequencingScientific computingProteomicsLight MicroscopyCell ServicesBiological Research FacilityFull details
Body composition and lung cancer-associated cachexia in TRACERx Authors (44)Othman Al-Sawaf Jakob Weiss Marcin Skrzypski Jie Min LamTakahiro Karasaki Francisco Zambrana[...]Nicolai Birkbak Hugo JWL Aerts TRACERx Consortium Mariam Jamal-HanjaniCharles Swanton Nature Medicine Published 1 April 2023 Crick labs/ facilitiesPeter Van LooCharles SwantonGeorge KassiotisFlow CytometryExperimental HistopathologyBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details
Evolutionary characterization of lung adenocarcinoma morphology in TRACERx Authors (53)Takahiro Karasaki David A Moore Selvaraju Veeriah Cristina Naceur-Lombardelli Antonia Toncheva Neil Magno[...] Andrew G Nicholson TRACERx Consortium Nicholas McGranahanCharles Swanton Mariam Jamal-Hanjani Nature Medicine Published 1 April 2023 Crick labs/ facilitiesPeter Van LooCharles SwantonGeorge KassiotisFlow CytometryExperimental HistopathologyBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details
Genomic-transcriptomic evolution in lung cancer and metastasis Authors (47) Carlos Martínez-Ruiz James RM Black Clare Puttick Mark S HillJonas DemeulemeesterElizabeth Larose Cadieux[...] Peter Van Loo Mariam Jamal-Hanjani TRACERx Consortium Charles Swanton Nicholas McGranahan Nature Published 20 April 2023 Crick labs/ facilitiesPeter Van LooCharles SwantonGeorge KassiotisJulian DownwardFlow CytometryExperimental HistopathologyBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details
The evolution of lung cancer and impact of subclonal selection in TRACERx Authors (81)Alexander FrankellMichelle DietzenMaise Al BakirEmilia LimTakahiro KarasakiSophie Ward[...] Simone Zaccaria TRACERx Consortium Mariam Jamal-Hanjani Nicholas McGranahanCharles Swanton Nature Published 20 April 2023 Crick labs/ facilitiesPeter Van LooCharles SwantonGeorge KassiotisFlow CytometryExperimental HistopathologyBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details
